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Illumina Body Map 2: averaged replicates

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Results for ACCCUGU

Z-value: 0.96

Motif logo

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miRNA associated with seed ACCCUGU

NamemiRBASE accession
hsa-miR-10a-5p
MIMAT0000253
hsa-miR-10b-5p
MIMAT0000254

Activity profile of ACCCUGU motif

Sorted Z-values of ACCCUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_45696253 2.04 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr12_+_125811162 1.85 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr5_-_160973649 1.58 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr1_-_217262969 1.58 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr3_-_9595480 1.57 ENST00000287585.6
LHFPL4
lipoma HMGIC fusion partner-like 4
chr2_-_2334888 1.56 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr8_+_1449532 1.49 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr7_-_44365020 1.46 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr4_-_100575781 1.38 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr1_+_57110972 1.38 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr2_+_166326157 1.34 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_167181917 1.33 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr6_+_107811162 1.29 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr5_+_143584814 1.28 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr4_+_47033345 1.25 ENST00000295454.3
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr17_+_4487294 1.23 ENST00000338859.4
SMTNL2
smoothelin-like 2
chr9_-_23821273 1.22 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr4_-_53525406 1.16 ENST00000451218.2
ENST00000441222.3
USP46
ubiquitin specific peptidase 46
chr1_+_110082487 1.14 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr10_-_62149433 1.14 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_47812321 1.12 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chrX_+_28605516 1.10 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr3_-_179754706 1.01 ENST00000465751.1
ENST00000467460.1
PEX5L
peroxisomal biogenesis factor 5-like
chr17_+_34058639 0.97 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr5_-_124080203 0.96 ENST00000504926.1
ZNF608
zinc finger protein 608
chr14_+_33408449 0.92 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr7_+_20370746 0.86 ENST00000222573.4
ITGB8
integrin, beta 8
chr19_-_55954230 0.84 ENST00000376325.4
SHISA7
shisa family member 7
chr14_+_85996471 0.79 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr15_-_65715401 0.77 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr6_-_11044509 0.75 ENST00000354666.3
ELOVL2
ELOVL fatty acid elongase 2
chr16_-_70719925 0.73 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr9_+_77112244 0.70 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr4_-_77135046 0.64 ENST00000264896.2
SCARB2
scavenger receptor class B, member 2
chr19_+_13135386 0.62 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_-_48143999 0.62 ENST00000439988.3
MDGA2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr19_+_10527449 0.59 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_+_134070439 0.59 ENST00000264360.5
PCDH10
protocadherin 10
chr3_+_85008089 0.58 ENST00000383699.3
CADM2
cell adhesion molecule 2
chr12_-_14956396 0.56 ENST00000535328.1
ENST00000261167.2
WBP11
WW domain binding protein 11
chr4_-_152147579 0.56 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr15_-_56209306 0.55 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_-_9970227 0.55 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr2_-_37193606 0.53 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr10_+_103113802 0.51 ENST00000370187.3
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr9_+_112403088 0.49 ENST00000448454.2
PALM2
paralemmin 2
chr11_+_66025167 0.48 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2
kinesin light chain 2
chr22_-_17602200 0.47 ENST00000399875.1
CECR6
cat eye syndrome chromosome region, candidate 6
chr1_-_85156216 0.47 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_+_22889953 0.46 ENST00000374644.4
ENST00000166244.3
ENST00000538803.1
EPHA8
EPH receptor A8
chr10_-_128994422 0.45 ENST00000522781.1
FAM196A
family with sequence similarity 196, member A
chr11_-_115375107 0.45 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr4_-_66536057 0.44 ENST00000273854.3
EPHA5
EPH receptor A5
chr2_-_69870835 0.41 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr11_+_20620946 0.41 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr9_-_127533519 0.41 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr9_+_129567282 0.41 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
ZBTB43
zinc finger and BTB domain containing 43
chr8_-_41655107 0.41 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ANK1
ankyrin 1, erythrocytic
chr4_+_184020398 0.40 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr2_+_97454321 0.40 ENST00000540067.1
CNNM4
cyclin M4
chr6_-_146135880 0.39 ENST00000237281.4
FBXO30
F-box protein 30
chr19_+_3880581 0.35 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr16_+_69599861 0.32 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_+_117002339 0.31 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr1_+_93913713 0.31 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr14_+_23775971 0.30 ENST00000250405.5
BCL2L2
BCL2-like 2
chr11_+_18344106 0.28 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr8_-_4852218 0.27 ENST00000400186.3
ENST00000602723.1
CSMD1
CUB and Sushi multiple domains 1
chr10_+_72972281 0.26 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr17_+_46125707 0.25 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr11_+_113930291 0.25 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr4_+_154125565 0.23 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr2_-_166060571 0.23 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr5_+_63461642 0.22 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr22_+_39898325 0.22 ENST00000325301.2
ENST00000404569.1
MIEF1
mitochondrial elongation factor 1
chr10_-_79686284 0.22 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr6_+_116421976 0.21 ENST00000319550.4
ENST00000419791.1
NT5DC1
5'-nucleotidase domain containing 1
chr20_+_55204351 0.21 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr8_+_22857048 0.19 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chrX_-_54384425 0.19 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr8_-_30891078 0.18 ENST00000339382.2
ENST00000475541.1
PURG
purine-rich element binding protein G
chr5_+_56205081 0.17 ENST00000285947.2
ENST00000541720.1
SETD9
SET domain containing 9
chr1_+_224301787 0.16 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr6_+_71377473 0.16 ENST00000370452.3
ENST00000316999.5
ENST00000370455.3
SMAP1
small ArfGAP 1
chrX_-_46618490 0.16 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr3_+_14989076 0.15 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr12_+_4918342 0.14 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr17_-_48207157 0.13 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr15_-_61521495 0.12 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr10_+_180987 0.12 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr17_-_49198216 0.12 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr18_-_33647487 0.11 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr9_+_100263912 0.11 ENST00000259365.4
TMOD1
tropomodulin 1
chr13_-_29069232 0.11 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr21_+_45285050 0.10 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_+_69864129 0.10 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr17_-_73775839 0.09 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr16_-_85722530 0.09 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr2_+_64681219 0.09 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr2_-_206950781 0.08 ENST00000403263.1
INO80D
INO80 complex subunit D
chr10_-_30348439 0.08 ENST00000375377.1
KIAA1462
KIAA1462
chr17_-_4167142 0.07 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr4_-_146859623 0.06 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr17_+_44928946 0.06 ENST00000290015.2
ENST00000393461.2
WNT9B
wingless-type MMTV integration site family, member 9B
chr19_-_14316980 0.05 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr6_+_15246501 0.05 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr7_-_138666053 0.05 ENST00000440172.1
ENST00000422774.1
KIAA1549
KIAA1549
chr2_+_215275771 0.05 ENST00000312504.5
ENST00000427124.1
VWC2L
von Willebrand factor C domain containing protein 2-like
chr18_+_43914159 0.04 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr19_+_13229126 0.04 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr3_-_9994021 0.04 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr1_+_89990431 0.04 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr17_+_45727204 0.03 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr7_+_94139105 0.03 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr1_+_169337172 0.03 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr2_-_164592497 0.03 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr3_+_183873098 0.02 ENST00000313143.3
DVL3
dishevelled segment polarity protein 3
chr9_-_115983641 0.02 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr4_-_111119804 0.02 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr10_-_75173785 0.01 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCCUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 2.7 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 1.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 2.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.6 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.3 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 1.2 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.4 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 1.6 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.9 GO:0090102 cochlea development(GO:0090102)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098855 HCN channel complex(GO:0098855)
0.3 0.9 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.5 GO:0016938 kinesin I complex(GO:0016938)
0.1 1.5 GO:0005883 neurofilament(GO:0005883)
0.1 2.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.4 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 1.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 1.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins