Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for AHR_ARNT2
Z-value: 3.41
Motif logo
Transcription factors associated with AHR_ARNT2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ARNT2 | hg19_v2_chr15_+_80696666_80696700 | 0.76 | 4.2e-07 | Click! |
| AHR | hg19_v2_chr7_+_17338239_17338262 | -0.17 | 3.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of AHR_ARNT2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 38.4 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 20.0 | GO:0097485 | neuron projection guidance(GO:0097485) |
| 0.3 | 18.6 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 18.2 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 5.7 | 17.2 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 0.3 | 15.8 | GO:0007616 | long-term memory(GO:0007616) |
| 0.5 | 14.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 1.2 | 14.2 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.1 | 14.2 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.7 | 13.9 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 54.5 | GO:0045202 | synapse(GO:0045202) |
| 0.1 | 39.0 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.2 | 33.9 | GO:0034705 | potassium channel complex(GO:0034705) |
| 0.0 | 22.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.6 | 21.7 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 20.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 20.0 | GO:0005874 | microtubule(GO:0005874) |
| 0.1 | 18.0 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.1 | 17.5 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 1.8 | 16.5 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 44.3 | GO:0005525 | GTP binding(GO:0005525) |
| 1.3 | 38.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.4 | 25.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 23.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.2 | 17.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 1.2 | 17.4 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.5 | 17.4 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 16.3 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.8 | 15.4 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.6 | 14.5 | GO:0098988 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 37.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.3 | 12.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.2 | 11.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 10.0 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 9.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.4 | 9.2 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 7.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 6.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 6.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.6 | PID LKB1 PATHWAY | LKB1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 35.5 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.4 | 25.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.5 | 18.9 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.8 | 18.7 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.2 | 15.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.4 | 14.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.6 | 13.9 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.5 | 12.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 10.7 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.3 | 9.2 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |