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Illumina Body Map 2: averaged replicates

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Results for ALX1_ARX

Z-value: 1.02

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.3 ALX homeobox 1
ARX
ENSG00000004848.6 aristaless related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARXhg19_v2_chrX_-_25034065_250340880.096.3e-01Click!
ALX1hg19_v2_chr12_+_85673868_85673885-0.077.1e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_95236551 4.62 ENST00000238558.3
GSC
goosecoid homeobox
chr14_+_22631122 4.61 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr3_-_27763803 2.76 ENST00000449599.1
EOMES
eomesodermin
chr3_-_27764190 2.47 ENST00000537516.1
EOMES
eomesodermin
chr5_+_96840389 2.39 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr1_-_151148492 2.25 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr1_-_151148442 2.23 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr6_-_66417107 2.01 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr3_-_3151664 1.96 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr12_+_54410664 1.91 ENST00000303406.4
HOXC4
homeobox C4
chr3_-_157824292 1.75 ENST00000483851.2
SHOX2
short stature homeobox 2
chr1_-_92371839 1.30 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr8_-_57472154 1.25 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
LINC00968
long intergenic non-protein coding RNA 968
chr17_+_61151306 1.19 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_-_19817869 1.18 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr3_+_138340049 1.13 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr8_-_57472137 1.11 ENST00000519144.1
LINC00968
long intergenic non-protein coding RNA 968
chr2_-_89160770 1.10 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr1_+_81106951 1.10 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chrX_+_107288197 1.09 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_107288280 1.08 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr8_+_86999516 1.07 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr7_-_115799942 1.06 ENST00000484212.1
TFEC
transcription factor EC
chrX_+_107288239 1.05 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr2_+_176994408 0.94 ENST00000429017.1
ENST00000313173.4
ENST00000544999.1
HOXD8
homeobox D8
chr10_-_29923893 0.93 ENST00000355867.4
SVIL
supervillin
chr2_-_89161432 0.93 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr10_-_75226166 0.91 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr2_-_145188137 0.87 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr13_+_74805561 0.83 ENST00000419499.1
LINC00402
long intergenic non-protein coding RNA 402
chr7_+_30589829 0.83 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr12_-_57873329 0.80 ENST00000424809.2
ARHGAP9
Rho GTPase activating protein 9
chr6_-_32908792 0.79 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_-_8964580 0.79 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr6_-_32908765 0.79 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr12_-_53601055 0.77 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr4_-_36245561 0.76 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_121659052 0.75 ENST00000512105.1
CTD-2544H17.1
CTD-2544H17.1
chr1_+_170632250 0.75 ENST00000367760.3
PRRX1
paired related homeobox 1
chr7_+_93535817 0.74 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr8_-_57472049 0.73 ENST00000523786.1
ENST00000521483.1
LINC00968
long intergenic non-protein coding RNA 968
chr12_-_53601000 0.73 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr14_-_83262540 0.73 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr11_+_128563652 0.73 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chrX_-_15332665 0.72 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr12_-_91546926 0.72 ENST00000550758.1
DCN
decorin
chr18_-_44181442 0.71 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr1_-_178838404 0.71 ENST00000444255.1
ANGPTL1
angiopoietin-like 1
chr2_-_145278475 0.68 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_206557366 0.67 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_57873631 0.65 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr2_+_36923830 0.64 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr1_+_192127578 0.64 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr14_-_52436247 0.62 ENST00000597846.1
AL358333.1
HCG2013195; Uncharacterized protein
chr12_+_14572070 0.61 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_+_36923933 0.60 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr12_-_89746264 0.57 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr6_-_133055896 0.57 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr3_+_151591422 0.57 ENST00000362032.5
SUCNR1
succinate receptor 1
chr10_-_50396425 0.54 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr17_+_44588877 0.54 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr12_-_92539614 0.54 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr16_+_68119247 0.54 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr12_-_89746173 0.53 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr8_+_77318769 0.53 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr19_+_50016610 0.52 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_+_119699864 0.52 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr16_+_68119324 0.52 ENST00000349223.5
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr16_+_68119440 0.52 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_-_50396407 0.51 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr2_+_119699742 0.51 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure
chr8_-_122653630 0.50 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr12_+_122241928 0.50 ENST00000604567.1
ENST00000542440.1
SETD1B
SET domain containing 1B
chr4_-_68829226 0.49 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr1_+_186265399 0.49 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr14_-_75083313 0.49 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr16_+_53469525 0.48 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr4_+_69313145 0.48 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr16_+_22518495 0.48 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chrX_-_11284095 0.47 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr1_+_186798073 0.47 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_-_133055815 0.47 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr9_+_44867571 0.46 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr2_-_89161064 0.46 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr8_+_19759228 0.46 ENST00000520959.1
LPL
lipoprotein lipase
chr11_+_108094786 0.45 ENST00000601453.1
ATM
ataxia telangiectasia mutated
chr3_-_191000172 0.45 ENST00000427544.2
UTS2B
urotensin 2B
chr2_-_145277882 0.45 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr10_+_69865866 0.45 ENST00000354393.2
MYPN
myopalladin
chr2_+_36923901 0.45 ENST00000457137.2
VIT
vitrin
chr15_+_42066632 0.45 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr10_-_31146615 0.44 ENST00000444692.2
ZNF438
zinc finger protein 438
chr12_-_52946923 0.43 ENST00000267119.5
KRT71
keratin 71
chr3_+_121774202 0.42 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr1_+_158978768 0.42 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr8_-_6420930 0.40 ENST00000325203.5
ANGPT2
angiopoietin 2
chr4_-_143227088 0.40 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr12_-_118796910 0.40 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr17_-_60885645 0.40 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr11_-_111649015 0.40 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr5_+_137722255 0.39 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr4_-_143226979 0.37 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr6_+_34204642 0.36 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chrX_+_77166172 0.36 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr6_+_15401075 0.35 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr17_+_39261584 0.35 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr1_+_154401791 0.35 ENST00000476006.1
IL6R
interleukin 6 receptor
chr11_-_96076334 0.35 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr10_-_50396357 0.35 ENST00000453436.1
ENST00000474718.1
C10orf128
chromosome 10 open reading frame 128
chr4_-_68829144 0.35 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr22_-_30642728 0.35 ENST00000403987.3
LIF
leukemia inhibitory factor
chr7_-_55620433 0.35 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr9_-_95298254 0.35 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr17_-_60885659 0.33 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr10_+_97803151 0.32 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr17_+_74463650 0.32 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr11_-_16419067 0.32 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr3_-_186262166 0.31 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_-_60885700 0.31 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr10_-_102989551 0.31 ENST00000370193.2
LBX1
ladybird homeobox 1
chr17_-_38956205 0.31 ENST00000306658.7
KRT28
keratin 28
chr6_-_26199499 0.30 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr12_+_1099675 0.30 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr6_-_150067696 0.30 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr1_-_178840157 0.29 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr2_+_58655461 0.29 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr5_-_39270725 0.29 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr16_-_21875424 0.29 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr12_-_125052010 0.28 ENST00000458234.1
NCOR2
nuclear receptor corepressor 2
chr1_+_62439037 0.28 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr3_+_138340067 0.27 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr4_-_119759795 0.27 ENST00000419654.2
SEC24D
SEC24 family member D
chrX_+_11311533 0.27 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr7_-_33842742 0.25 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
RP11-89N17.4
chr7_+_135710494 0.25 ENST00000440744.2
AC024084.1
AC024084.1
chr2_+_54683419 0.25 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_-_52989217 0.25 ENST00000570287.2
TCF4
transcription factor 4
chr9_+_135854091 0.24 ENST00000450530.1
ENST00000534944.1
GFI1B
growth factor independent 1B transcription repressor
chrX_+_39868501 0.24 ENST00000447651.1
AC092198.1
AC092198.1
chr2_+_29001711 0.24 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr6_-_137314371 0.24 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr14_+_57671888 0.24 ENST00000391612.1
AL391152.1
AL391152.1
chr12_-_15815626 0.24 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr8_-_62602327 0.24 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr18_-_52989525 0.23 ENST00000457482.3
TCF4
transcription factor 4
chr3_+_12329358 0.23 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr3_+_12329397 0.23 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr3_-_101039402 0.22 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr10_-_99030395 0.22 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr6_-_26199471 0.22 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr4_+_76649753 0.22 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr11_-_58035732 0.22 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chrX_+_16668278 0.22 ENST00000380200.3
S100G
S100 calcium binding protein G
chr3_-_124774802 0.22 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr5_-_59783882 0.22 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_118628350 0.22 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr14_-_81425828 0.22 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr4_-_103940791 0.22 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr15_-_98836406 0.22 ENST00000560360.1
CTD-2544M6.1
CTD-2544M6.1
chr5_+_68860949 0.21 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr5_-_60411762 0.21 ENST00000594278.1
AC008498.1
AC008498.1
chr17_-_71228357 0.21 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr14_-_57197224 0.21 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr5_+_140227357 0.21 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr3_-_195310802 0.21 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr14_+_22951993 0.20 ENST00000390485.1
TRAJ53
T cell receptor alpha joining 53
chr14_-_78083112 0.20 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr2_+_161993465 0.20 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr5_+_91378410 0.19 ENST00000507217.1
RP11-348J24.2
RP11-348J24.2
chr3_-_32544900 0.19 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chrX_+_107037451 0.19 ENST00000372379.2
NCBP2L
nuclear cap binding protein subunit 2-like
chr6_-_170893268 0.19 ENST00000538195.1
PDCD2
programmed cell death 2
chr6_-_111804905 0.19 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_+_244214577 0.18 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr9_+_123884038 0.18 ENST00000373847.1
CNTRL
centriolin
chr16_+_24549014 0.18 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr2_-_145275228 0.18 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr9_+_88556444 0.18 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr5_-_134735568 0.18 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr2_+_161993412 0.18 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr21_-_43346790 0.17 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr1_+_158323755 0.17 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chr2_-_145275828 0.17 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr4_+_118955500 0.17 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_-_83769996 0.17 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr12_+_59989918 0.17 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_-_93520259 0.17 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr15_+_43477580 0.16 ENST00000356633.5
CCNDBP1
cyclin D-type binding-protein 1
chrX_+_36254051 0.16 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr2_+_102413726 0.16 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_-_118628315 0.16 ENST00000540561.1
TAOK3
TAO kinase 3
chr5_+_145826867 0.16 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr12_+_10163231 0.16 ENST00000396502.1
ENST00000338896.5
CLEC12B
C-type lectin domain family 12, member B
chr1_-_154600421 0.16 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr4_+_95128996 0.16 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_+_97709725 0.16 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr6_+_3259122 0.15 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr2_-_31440377 0.15 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr8_-_61880248 0.15 ENST00000525556.1
AC022182.3
AC022182.3
chr3_+_130569429 0.15 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.5 4.6 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.5 1.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4 4.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 2.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.3 1.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 2.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 1.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.7 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.7 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.5 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.1 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 2.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 2.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 1.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.9 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 1.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.4 2.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.8 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 3.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 5.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 5.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.5 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 2.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 2.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005262 calcium channel activity(GO:0005262) calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 5.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones