Motif ID: ARID5A

Z-value: 1.650


Transcription factors associated with ARID5A:

Gene SymbolEntrez IDGene Name
ARID5A ENSG00000196843.11 ARID5A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARID5Ahg19_v2_chr2_+_97202480_972024990.364.1e-02Click!


Activity profile for motif ARID5A.

activity profile for motif ARID5A


Sorted Z-values histogram for motif ARID5A

Sorted Z-values for motif ARID5A



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_217724767 4.670 ENST00000236979.2
TNP1
transition protein 1 (during histone to protamine replacement)
chr6_-_49834240 3.718 ENST00000335847.4
CRISP1
cysteine-rich secretory protein 1
chr6_-_49834209 3.630 ENST00000507853.1
CRISP1
cysteine-rich secretory protein 1
chr3_-_150421728 3.445 ENST00000295910.6
ENST00000491361.1
FAM194A

family with sequence similarity 194, member A

chr4_-_177116772 3.345 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr1_+_40713573 3.198 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr8_+_24298531 3.162 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr7_+_142031986 2.991 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr8_+_24298597 2.794 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr18_-_61329118 2.565 ENST00000332821.8
ENST00000283752.5
SERPINB3

serpin peptidase inhibitor, clade B (ovalbumin), member 3

chr2_+_152214098 2.503 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_159848807 2.450 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr16_-_11375179 2.399 ENST00000312511.3
PRM1
protamine 1
chr5_+_159848854 2.399 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr11_+_61976137 2.358 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr11_-_26588634 2.300 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chrX_+_37850026 2.087 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr7_-_38339890 2.060 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr1_-_76398077 2.024 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chrX_+_36053908 1.948 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr3_-_150421752 1.885 ENST00000498386.1
FAM194A
family with sequence similarity 194, member A
chr10_+_127661942 1.881 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1


fibronectin type III and ankyrin repeat domains 1


chrX_+_107288239 1.865 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr16_+_86229728 1.856 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr8_+_24298438 1.854 ENST00000441335.2
ADAM7
ADAM metallopeptidase domain 7
chr20_+_31870927 1.829 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr18_-_69449517 1.817 ENST00000584810.1
RP11-723G8.2
Uncharacterized protein
chr15_+_45248880 1.805 ENST00000340827.3
C15orf43
chromosome 15 open reading frame 43
chr3_-_107596910 1.780 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635












long intergenic non-protein coding RNA 635












chrX_+_27608490 1.773 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr10_-_23528745 1.767 ENST00000376501.5
C10orf115
chromosome 10 open reading frame 115
chrX_+_36246735 1.761 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr5_-_59668541 1.739 ENST00000514552.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_131879205 1.712 ENST00000231454.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr19_-_42947121 1.707 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr2_+_79252822 1.700 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chrX_+_107288280 1.688 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr1_-_99999571 1.673 ENST00000438829.2
RP11-413P11.1
RP11-413P11.1
chr2_+_74011316 1.666 ENST00000409561.1
C2orf78
chromosome 2 open reading frame 78
chr13_+_75126978 1.665 ENST00000596240.1
ENST00000451336.2
LINC00347

long intergenic non-protein coding RNA 347

chr2_+_149974684 1.660 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr1_+_94798754 1.646 ENST00000418242.1
RP11-148B18.3
RP11-148B18.3
chr2_+_79252804 1.645 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr9_-_34381536 1.644 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24


chromosome 9 open reading frame 24


chr9_-_34381511 1.598 ENST00000379124.1
C9orf24
chromosome 9 open reading frame 24
chr10_+_118083919 1.596 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr6_-_49931818 1.593 ENST00000322066.3
DEFB114
defensin, beta 114
chr11_-_102595512 1.562 ENST00000438475.2
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr5_-_156593273 1.557 ENST00000302938.4
FAM71B
family with sequence similarity 71, member B
chrX_+_79675965 1.555 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr10_+_32856764 1.544 ENST00000375030.2
ENST00000375028.3
C10orf68

Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.

chr7_-_91808441 1.533 ENST00000437357.1
ENST00000458448.1
LRRD1

leucine-rich repeats and death domain containing 1

chr12_+_85430110 1.528 ENST00000393212.3
ENST00000393217.2
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr3_-_167191814 1.521 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr11_-_125648690 1.517 ENST00000436890.2
ENST00000358524.3
PATE2

prostate and testis expressed 2

chr20_-_5426332 1.508 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chrX_+_55246771 1.502 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chr11_+_60102304 1.502 ENST00000300182.4
MS4A6E
membrane-spanning 4-domains, subfamily A, member 6E
chr9_-_23779367 1.497 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr1_-_213020991 1.473 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chrX_+_107288197 1.454 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr11_+_60197040 1.452 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr20_+_17680587 1.418 ENST00000427254.1
ENST00000377805.3
BANF2

barrier to autointegration factor 2

chr1_+_158815588 1.407 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chrX_+_36065053 1.404 ENST00000313548.4
CHDC2
calponin homology domain containing 2
chr10_-_30918669 1.402 ENST00000375318.2
LYZL2
lysozyme-like 2
chr6_-_49712147 1.390 ENST00000433368.2
ENST00000354620.4
CRISP3

cysteine-rich secretory protein 3

chr8_-_57472154 1.390 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
LINC00968



long intergenic non-protein coding RNA 968



chrX_+_36254051 1.389 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr13_+_43355732 1.385 ENST00000313851.1
FAM216B
family with sequence similarity 216, member B
chr7_+_16566449 1.371 ENST00000401542.2
LRRC72
leucine rich repeat containing 72
chr1_-_89736434 1.366 ENST00000370459.3
GBP5
guanylate binding protein 5
chr15_+_22368478 1.355 ENST00000332663.2
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr6_+_139135648 1.345 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr4_+_71248795 1.344 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr1_-_85358850 1.336 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr16_-_52061283 1.335 ENST00000566314.1
C16orf97
chromosome 16 open reading frame 97
chr13_+_43355683 1.309 ENST00000537894.1
FAM216B
family with sequence similarity 216, member B
chr6_+_132455526 1.308 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr19_+_56368803 1.301 ENST00000587891.1
NLRP4
NLR family, pyrin domain containing 4
chr4_+_68424434 1.288 ENST00000265404.2
ENST00000396225.1
STAP1

signal transducing adaptor family member 1

chr8_-_19102999 1.272 ENST00000517949.1
RP11-1080G15.1
RP11-1080G15.1
chr16_-_58328923 1.260 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54


protease, serine, 54


chr2_-_69180083 1.259 ENST00000328895.4
GKN2
gastrokine 2
chr3_+_26735991 1.255 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr8_+_36641842 1.245 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr4_+_94125100 1.245 ENST00000512631.1
GRID2
glutamate receptor, ionotropic, delta 2
chr12_-_45269430 1.229 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr9_-_24545850 1.218 ENST00000543880.2
ENST00000418122.1
IZUMO3

IZUMO family member 3

chr10_-_22498950 1.212 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr1_+_170904612 1.211 ENST00000367759.4
ENST00000367758.3
MROH9

maestro heat-like repeat family member 9

chr3_+_14716606 1.182 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20


chromosome 3 open reading frame 20


chr5_-_61031495 1.181 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2

CTD-2170G1.2

chr3_+_94657016 1.177 ENST00000462219.1
LINC00879
long intergenic non-protein coding RNA 879
chr10_-_75118471 1.171 ENST00000340329.3
TTC18
tetratricopeptide repeat domain 18
chr20_+_55904815 1.169 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11



SPO11 meiotic protein covalently bound to DSB



chr12_+_8608522 1.167 ENST00000382073.3
CLEC6A
C-type lectin domain family 6, member A
chr17_+_61473104 1.164 ENST00000583016.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_-_46262541 1.160 ENST00000579336.1
SKAP1
src kinase associated phosphoprotein 1
chr6_-_49712072 1.154 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr7_+_142000747 1.149 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr4_-_122148620 1.143 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr9_-_107299137 1.138 ENST00000374781.2
OR13C3
olfactory receptor, family 13, subfamily C, member 3
chr3_-_157221128 1.131 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr20_+_17680599 1.129 ENST00000246090.5
BANF2
barrier to autointegration factor 2
chr11_+_60282862 1.119 ENST00000378186.2
ENST00000378185.2
ENST00000437058.2
ENST00000527948.1
MS4A13



membrane-spanning 4-domains, subfamily A, member 13



chr15_-_41522889 1.106 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1


exonuclease 3'-5' domain containing 1


chr6_-_136571400 1.101 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2


mitochondrial fission regulator 2


chr19_-_56704421 1.099 ENST00000358992.3
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr7_-_48068671 1.078 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr6_+_15401075 1.072 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr6_-_130543958 1.067 ENST00000437477.2
ENST00000439090.2
SAMD3

sterile alpha motif domain containing 3

chr7_-_16921601 1.061 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3


anterior gradient 3


chr1_-_149459549 1.059 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr22_-_50523843 1.054 ENST00000535444.1
ENST00000431262.2
MLC1

megalencephalic leukoencephalopathy with subcortical cysts 1

chr3_+_130279178 1.043 ENST00000358511.6
ENST00000453409.2
COL6A6

collagen, type VI, alpha 6

chr2_-_166930131 1.041 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr6_+_132455118 1.034 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr6_-_49712091 1.032 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr5_+_54398463 1.018 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr11_+_71544246 1.011 ENST00000328698.1
DEFB108B
defensin, beta 108B
chr12_+_9980113 1.010 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr12_+_9980069 0.995 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1


killer cell lectin-like receptor subfamily F, member 1


chr12_+_10460549 0.992 ENST00000543420.1
ENST00000543777.1
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr16_+_31366536 0.989 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_77333117 0.987 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr14_+_39944025 0.984 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr12_+_81664424 0.983 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3

RP11-121G22.3

chr19_+_55014085 0.982 ENST00000351841.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr6_-_49712123 0.975 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr16_-_58328884 0.973 ENST00000569079.1
PRSS54
protease, serine, 54
chr12_-_4758159 0.971 ENST00000545990.2
AKAP3
A kinase (PRKA) anchor protein 3
chr2_-_69180012 0.968 ENST00000481498.1
GKN2
gastrokine 2
chr5_-_131892501 0.965 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr11_+_60197069 0.963 ENST00000528905.1
ENST00000528093.1
MS4A5

membrane-spanning 4-domains, subfamily A, member 5

chrX_+_8432871 0.962 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B


variable charge, X-linked 3B


chr16_-_58328870 0.953 ENST00000543437.1
PRSS54
protease, serine, 54
chr10_+_97759848 0.940 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B


coiled-coil and C2 domain containing 2B


chr14_-_25045446 0.937 ENST00000216336.2
CTSG
cathepsin G
chr10_+_97709725 0.937 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr10_+_47746929 0.924 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr2_-_39456673 0.897 ENST00000378803.1
ENST00000395035.3
CDKL4

cyclin-dependent kinase-like 4

chr14_+_20295608 0.885 ENST00000568211.1
ENST00000315947.1
OR4N2

olfactory receptor, family 4, subfamily N, member 2

chr5_+_57787254 0.879 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GAPT


GRB2-binding adaptor protein, transmembrane


chr10_+_106113515 0.879 ENST00000369704.3
ENST00000312902.5
CCDC147

coiled-coil domain containing 147

chrX_+_55246818 0.874 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr22_-_32766972 0.873 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr8_+_7682694 0.868 ENST00000335186.2
DEFB106A
defensin, beta 106A
chr6_+_31707725 0.865 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5






mutS homolog 5






chr12_+_40787194 0.864 ENST00000425730.2
ENST00000454784.4
MUC19

mucin 19, oligomeric

chr7_-_38295997 0.857 ENST00000390334.1
TRGJP2
T cell receptor gamma joining P2
chr3_-_108672742 0.855 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr21_+_43823983 0.852 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A



ubiquitin associated and SH3 domain containing A



chr14_-_21029090 0.844 ENST00000338904.3
ENST00000554964.1
ENST00000555230.1
ENST00000557068.1
ENST00000404716.3
ENST00000556208.1
ENST00000553541.1
ENST00000429244.2
ENST00000553706.1
ENST00000557209.1
RNASE9









ribonuclease, RNase A family, 9 (non-active)









chr22_-_32767017 0.833 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr7_+_50135433 0.829 ENST00000297001.6
C7orf72
chromosome 7 open reading frame 72
chrX_-_142804516 0.828 ENST00000370498.1
SPANXN2
SPANX family, member N2
chrX_-_107682702 0.820 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr12_-_45315625 0.813 ENST00000552993.1
NELL2
NEL-like 2 (chicken)
chrX_+_114423963 0.812 ENST00000424776.3
RBMXL3
RNA binding motif protein, X-linked-like 3
chr12_-_15082050 0.812 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr2_-_46621306 0.805 ENST00000418415.1
AC016912.3
AC016912.3
chr1_+_209602771 0.799 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr12_-_45269251 0.795 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr6_-_133055896 0.794 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr17_-_71223839 0.791 ENST00000579872.1
ENST00000580032.1
FAM104A

family with sequence similarity 104, member A

chr18_-_19994830 0.790 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr4_+_100737954 0.787 ENST00000296414.7
ENST00000512369.1
DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

chr5_-_19988339 0.782 ENST00000382275.1
CDH18
cadherin 18, type 2
chrX_-_154493791 0.779 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr11_-_26744908 0.769 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr11_+_128563652 0.763 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_133084580 0.759 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr20_+_15177480 0.758 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr2_-_208989225 0.750 ENST00000264376.4
CRYGD
crystallin, gamma D
chr2_-_118943930 0.749 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1


AC093901.1


chr9_+_71357171 0.749 ENST00000440050.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr3_+_94657086 0.742 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chr2_+_90024732 0.740 ENST00000390268.2
IGKV2D-26
immunoglobulin kappa variable 2D-26
chr22_+_32754139 0.738 ENST00000382088.3
RFPL3
ret finger protein-like 3
chr6_+_26199737 0.734 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr12_+_70219052 0.725 ENST00000552032.2
ENST00000547771.2
MYRFL

myelin regulatory factor-like

chr12_-_10542617 0.719 ENST00000240618.6
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr19_+_55014013 0.705 ENST00000301202.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr12_-_10607084 0.705 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
KLRC1


killer cell lectin-like receptor subfamily C, member 1


chr14_+_22788560 0.703 ENST00000390468.1
TRAV41
T cell receptor alpha variable 41
chr15_-_58571445 0.700 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_152178320 0.698 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr7_+_135710494 0.696 ENST00000440744.2
AC024084.1
AC024084.1
chr12_-_10562356 0.693 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr8_+_55528627 0.690 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr18_+_61223393 0.687 ENST00000269491.1
ENST00000382768.1
SERPINB12

serpin peptidase inhibitor, clade B (ovalbumin), member 12

chr22_-_32860427 0.685 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC


BPI fold containing family C


chr22_-_23922448 0.674 ENST00000438703.1
ENST00000330377.2
IGLL1

immunoglobulin lambda-like polypeptide 1

chr17_-_43339453 0.669 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr2_+_101223490 0.667 ENST00000414647.1
ENST00000424342.1
AC068538.4

AC068538.4

chr14_+_56584414 0.666 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr22_-_29457832 0.664 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr7_-_130066571 0.656 ENST00000492389.1
CEP41
centrosomal protein 41kDa
chr4_-_90756769 0.656 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.5 4.7 GO:0000012 single strand break repair(GO:0000012)
0.4 1.3 GO:0032060 bleb assembly(GO:0032060)
0.4 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 7.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 1.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.3 0.9 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.2 0.7 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:0002124 territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625)
0.1 0.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.1 3.6 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0003350 cardiac right ventricle morphogenesis(GO:0003215) pulmonary myocardium development(GO:0003350)
0.1 0.5 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.1 0.6 GO:0071436 sodium ion export(GO:0071436)
0.1 0.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.1 1.2 GO:0007141 male meiosis I(GO:0007141)
0.1 0.9 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 2.4 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 1.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 1.2 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.7 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.4 GO:0002431 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 1.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.6 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.4 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.2 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 2.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 5.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.4 GO:0009629 response to gravity(GO:0009629)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298) minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 4.6 GO:0007059 chromosome segregation(GO:0007059)
0.0 2.6 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.3 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 4.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.7 GO:0034614 cellular response to reactive oxygen species(GO:0034614)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 4.6 GO:0042581 specific granule(GO:0042581)
0.2 0.5 GO:0060091 kinocilium(GO:0060091)
0.2 3.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.8 GO:0005903 brush border(GO:0005903)
0.1 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) synaptic cleft(GO:0043083) cell body membrane(GO:0044298)
0.1 0.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.7 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.2 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000267 obsolete cell fraction(GO:0000267)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 1.1 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 1.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.7 GO:0043205 fibril(GO:0043205)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.4 2.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 2.0 GO:0005497 androgen binding(GO:0005497)
0.2 1.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 1.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 2.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0031386 protein tag(GO:0031386)
0.1 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0051381 histamine binding(GO:0051381)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 5.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 9.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.8 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.0 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.7 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 4.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.7 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway