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Illumina Body Map 2: averaged replicates

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Results for ARID5B

Z-value: 1.41

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Transcription factors associated with ARID5B

Gene Symbol Gene ID Gene Info
ENSG00000150347.10 AT-rich interaction domain 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Bhg19_v2_chr10_+_63808970_638089900.681.7e-05Click!

Activity profile of ARID5B motif

Sorted Z-values of ARID5B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_76995855 4.16 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr9_+_13446472 2.75 ENST00000428006.2
RP11-536O18.1
chr3_+_155755482 2.45 ENST00000472028.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr8_+_19759228 2.44 ENST00000520959.1
lipoprotein lipase
chr7_+_36450169 2.14 ENST00000428612.1
anillin, actin binding protein
chr14_+_32798547 2.03 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr14_+_32798462 1.87 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr17_-_3599492 1.86 ENST00000435558.1
ENST00000345901.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599696 1.84 ENST00000225328.5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_10452929 1.80 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
myosin, heavy chain 2, skeletal muscle, adult
chr11_-_111794446 1.66 ENST00000527950.1
crystallin, alpha B
chr3_+_63428752 1.62 ENST00000295894.5
synaptoporin
chr18_+_32173276 1.56 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr12_-_8814669 1.55 ENST00000535411.1
ENST00000540087.1
microfibrillar associated protein 5
chr12_-_8815215 1.54 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr11_-_102714534 1.49 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_-_8815299 1.46 ENST00000535336.1
microfibrillar associated protein 5
chr1_+_86934526 1.44 ENST00000394711.1
chloride channel accessory 1
chr10_-_98118724 1.43 ENST00000393870.2
oligodendrocytic myelin paranodal and inner loop protein
chr10_+_53806501 1.40 ENST00000373975.2
protein kinase, cGMP-dependent, type I
chr12_-_122879969 1.39 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr22_-_22090043 1.38 ENST00000403503.1
yippee-like 1 (Drosophila)
chr15_+_51669444 1.37 ENST00000396399.2
gliomedin
chrX_+_102585124 1.29 ENST00000332431.4
ENST00000372666.1
transcription elongation factor A (SII)-like 7
chr2_+_168675182 1.27 ENST00000305861.1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_-_144995074 1.22 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr15_+_51669513 1.21 ENST00000558426.1
gliomedin
chr1_-_144994909 1.20 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr2_-_214016314 1.19 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr22_-_22090064 1.17 ENST00000339468.3
yippee-like 1 (Drosophila)
chrX_+_149867681 1.16 ENST00000438018.1
ENST00000436701.1
myotubularin related protein 1
chr15_+_57891609 1.06 ENST00000569089.1
myocardial zonula adherens protein
chr7_+_143080063 1.02 ENST00000446634.1
zyxin
chr1_-_40137710 1.02 ENST00000235628.1
5'-nucleotidase, cytosolic IA
chr12_-_6809958 1.01 ENST00000320591.5
ENST00000534837.1
PILR alpha associated neural protein
chr17_-_76732928 1.00 ENST00000589768.1
cytohesin 1
chr10_-_75193308 0.99 ENST00000299432.2
MSS51 mitochondrial translational activator
chr10_-_75351088 0.99 ENST00000451492.1
ENST00000413442.1
ubiquitin specific peptidase 54
chr12_-_118796971 0.98 ENST00000542902.1
TAO kinase 3
chr14_+_22458631 0.98 ENST00000390444.1
T cell receptor alpha variable 16
chr2_-_231825668 0.98 ENST00000392039.2
G protein-coupled receptor 55
chr12_-_118796910 0.94 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr22_+_20877924 0.93 ENST00000445189.1
mediator complex subunit 15
chr5_-_88179017 0.92 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
myocyte enhancer factor 2C
chr5_+_155753745 0.92 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chrX_-_49089771 0.90 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
calcium channel, voltage-dependent, L type, alpha 1F subunit
chrX_-_11308598 0.89 ENST00000380717.3
Rho GTPase activating protein 6
chr11_+_1093318 0.89 ENST00000333592.6
mucin 2, oligomeric mucus/gel-forming
chr3_+_68053359 0.82 ENST00000478136.1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr4_-_44653636 0.82 ENST00000415895.4
ENST00000332990.5
Yip1 domain family, member 7
chr12_-_10007448 0.82 ENST00000538152.1
C-type lectin domain family 2, member B
chr12_-_48597170 0.81 ENST00000310248.2
olfactory receptor, family 10, subfamily AD, member 1
chr10_-_29923893 0.81 ENST00000355867.4
supervillin
chr5_+_161495038 0.79 ENST00000393933.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr14_+_23009190 0.79 ENST00000390532.1
T cell receptor alpha joining 5
chr4_+_95376396 0.78 ENST00000508216.1
ENST00000514743.1
PDZ and LIM domain 5
chr10_-_128210005 0.78 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
chromosome 10 open reading frame 90
chr6_+_155443048 0.77 ENST00000535583.1
T-cell lymphoma invasion and metastasis 2
chr1_+_95975672 0.76 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr9_+_77230499 0.75 ENST00000396204.2
RAR-related orphan receptor B
chr7_+_153749732 0.75 ENST00000377770.3
dipeptidyl-peptidase 6
chr5_+_161277603 0.74 ENST00000519621.1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_44889697 0.73 ENST00000443020.2
ring finger protein 220
chr1_+_78245303 0.72 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr1_-_144994840 0.72 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr6_-_15548591 0.71 ENST00000509674.1
dystrobrevin binding protein 1
chr20_+_9966728 0.71 ENST00000449270.1
RP5-839B4.8
chr2_-_74618964 0.70 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr2_-_40680578 0.70 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_168698433 0.69 ENST00000367817.3
dermatopontin
chr11_-_78052923 0.69 ENST00000340149.2
GRB2-associated binding protein 2
chr11_-_104769141 0.68 ENST00000508062.1
ENST00000422698.2
caspase 12 (gene/pseudogene)
chr1_+_47264711 0.68 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
cytochrome P450, family 4, subfamily B, polypeptide 1
chr17_-_76713100 0.67 ENST00000585509.1
cytohesin 1
chr19_+_35849362 0.66 ENST00000327809.4
free fatty acid receptor 3
chr12_+_93096619 0.66 ENST00000397833.3
chromosome 12 open reading frame 74
chr3_-_98241713 0.65 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
claudin domain containing 1
chr4_-_57524061 0.65 ENST00000508121.1
HOP homeobox
chr11_-_73882249 0.63 ENST00000535954.1
C2 calcium-dependent domain containing 3
chr5_+_175288631 0.63 ENST00000509837.1
complexin 2
chr1_-_115292591 0.62 ENST00000438362.2
cold shock domain containing E1, RNA-binding
chr7_+_31726822 0.61 ENST00000409146.3
protein phosphatase 1, regulatory subunit 17
chr3_-_98241598 0.60 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
claudin domain containing 1
chr3_-_151102529 0.60 ENST00000302632.3
purinergic receptor P2Y, G-protein coupled, 12
chr14_-_52436247 0.60 ENST00000597846.1
HCG2013195; Uncharacterized protein
chr1_+_104159999 0.60 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr4_-_159094194 0.59 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chrX_-_33229636 0.58 ENST00000357033.4
dystrophin
chr20_-_45980621 0.57 ENST00000446894.1
zinc finger, MYND-type containing 8
chr12_+_56324933 0.57 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr10_+_4828815 0.57 ENST00000533295.1
aldo-keto reductase family 1, member E2
chr2_-_74619152 0.56 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr18_+_32556892 0.56 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr1_+_158975744 0.55 ENST00000426592.2
interferon, gamma-inducible protein 16
chr6_+_80341000 0.53 ENST00000369838.4
SH3 domain binding glutamic acid-rich protein like 2
chr1_+_43855545 0.53 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr16_-_3422283 0.53 ENST00000399974.3
MT-RNR2-like 4
chr14_+_85994943 0.53 ENST00000553678.1
Uncharacterized protein
chr7_+_153749471 0.52 ENST00000406326.1
dipeptidyl-peptidase 6
chr3_-_52713729 0.52 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
polybromo 1
chr3_-_15540055 0.52 ENST00000605797.1
ENST00000435459.2
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr6_-_137494775 0.51 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
interleukin 22 receptor, alpha 2
chr1_+_6615241 0.51 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
taste receptor, type 1, member 1
chr22_+_42086547 0.50 ENST00000402966.1
chromosome 22 open reading frame 46
chr1_+_151739131 0.50 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr5_+_118691706 0.50 ENST00000415806.2
tumor necrosis factor, alpha-induced protein 8
chr1_+_32608566 0.49 ENST00000545542.1
karyopherin alpha 6 (importin alpha 7)
chr1_-_149459549 0.49 ENST00000369175.3
family with sequence similarity 72, member C
chr2_+_7118755 0.49 ENST00000433456.1
ring finger protein 144A
chr3_-_98241760 0.49 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr6_+_122720681 0.49 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr5_+_446253 0.48 ENST00000315013.5
exocyst complex component 3
chr12_+_56324756 0.48 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr19_+_38308119 0.48 ENST00000592103.1
CTD-2554C21.2
chr6_+_132891461 0.47 ENST00000275198.1
trace amine associated receptor 6
chr3_+_111805182 0.46 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52
chr5_-_88179302 0.46 ENST00000504921.2
myocyte enhancer factor 2C
chr7_-_37488777 0.46 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr19_-_45579762 0.46 ENST00000303809.2
zinc finger protein 296
chr1_+_43855560 0.45 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chrX_-_57164058 0.45 ENST00000374906.3
spindlin family, member 2A
chr1_+_78245466 0.45 ENST00000477627.2
family with sequence similarity 73, member A
chr1_-_247836365 0.45 ENST00000359688.2
olfactory receptor, family 13, subfamily G, member 1
chr17_-_36358166 0.44 ENST00000537432.1
TBC1 domain family, member 3
chr1_-_224624730 0.44 ENST00000445239.1
WD repeat domain 26
chr1_+_248128535 0.44 ENST00000366480.3
olfactory receptor, family 2, subfamily AK, member 2
chr19_+_38307999 0.44 ENST00000589653.1
ENST00000590433.1
CTD-2554C21.2
chr9_+_116267536 0.44 ENST00000374136.1
regulator of G-protein signaling 3
chr12_+_56325231 0.44 ENST00000549368.1
diacylglycerol kinase, alpha 80kDa
chr22_+_19467261 0.43 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr6_+_117198400 0.43 ENST00000332958.2
regulatory factor X, 6
chr12_-_11339543 0.42 ENST00000334266.1
taste receptor, type 2, member 42
chr1_+_87458692 0.42 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr3_-_98241358 0.42 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chrX_-_11369656 0.42 ENST00000413512.3
Rho GTPase activating protein 6
chr18_-_53303123 0.41 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr11_+_3968573 0.41 ENST00000532990.1
stromal interaction molecule 1
chr3_-_139396853 0.41 ENST00000406164.1
ENST00000406824.1
nicotinamide nucleotide adenylyltransferase 3
chr5_-_64920115 0.38 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr5_+_118668846 0.38 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chr15_+_22368478 0.37 ENST00000332663.2
olfactory receptor, family 4, subfamily M, member 2
chr9_+_114287433 0.37 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
zinc finger protein 483
chr17_-_21454898 0.36 ENST00000391411.5
ENST00000412778.3
chromosome 17 open reading frame 51
chr1_-_161337662 0.36 ENST00000367974.1
chromosome 1 open reading frame 192
chr4_-_90229142 0.34 ENST00000609438.1
GPRIN family member 3
chr6_-_30080876 0.33 ENST00000376734.3
tripartite motif containing 31
chr12_+_54366894 0.33 ENST00000546378.1
ENST00000243082.4
homeobox C11
chr1_-_157014865 0.33 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr15_-_80263506 0.33 ENST00000335661.6
BCL2-related protein A1
chr8_+_65285851 0.33 ENST00000520799.1
ENST00000521441.1
long intergenic non-protein coding RNA 966
chr12_-_10962767 0.32 ENST00000240691.2
taste receptor, type 2, member 9
chr12_+_79258444 0.32 ENST00000261205.4
synaptotagmin I
chr1_-_31538517 0.32 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
pumilio RNA-binding family member 1
chr2_+_133874577 0.31 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr12_-_43833515 0.31 ENST00000549670.1
ENST00000395541.2
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr7_-_37488834 0.30 ENST00000310758.4
engulfment and cell motility 1
chr17_+_3379284 0.30 ENST00000263080.2
aspartoacylase
chr13_+_53216565 0.30 ENST00000357495.2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr12_+_8309630 0.30 ENST00000396570.3
zinc finger protein 705A
chr11_+_30253410 0.30 ENST00000533718.1
follicle stimulating hormone, beta polypeptide
chr12_+_52281744 0.30 ENST00000301190.6
ENST00000538991.1
ankyrin repeat domain 33
chr4_-_25871127 0.28 ENST00000503085.1
RP13-494C23.1
chr2_-_114300213 0.28 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
RP11-395L14.4
chr13_-_30948036 0.27 ENST00000447147.1
ENST00000444319.1
long intergenic non-protein coding RNA 426
chr6_+_32812568 0.27 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_126661253 0.27 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
centromere protein W
chr20_-_9819674 0.26 ENST00000378429.3
p21 protein (Cdc42/Rac)-activated kinase 7
chr8_-_116504448 0.26 ENST00000518018.1
trichorhinophalangeal syndrome I
chr3_+_183770835 0.25 ENST00000318351.1
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
chrX_+_106769876 0.25 ENST00000439554.1
FERM and PDZ domain containing 3
chr12_-_15038779 0.25 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr12_-_124456598 0.25 ENST00000539761.1
ENST00000539551.1
coiled-coil domain containing 92
chrX_+_54466829 0.24 ENST00000375151.4
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr8_-_101322132 0.24 ENST00000523481.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr12_+_79258547 0.24 ENST00000457153.2
synaptotagmin I
chr15_+_25068773 0.24 ENST00000400100.1
ENST00000400098.1
small nuclear ribonucleoprotein polypeptide N
chr3_-_197024394 0.24 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
discs, large homolog 1 (Drosophila)
chr3_+_43328004 0.24 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr5_+_154393260 0.24 ENST00000435029.4
kinesin family member 4B
chr3_+_161214596 0.23 ENST00000327928.4
otolin 1
chr4_+_40201954 0.23 ENST00000511121.1
ras homolog family member H
chr7_+_143792141 0.23 ENST00000408949.2
olfactory receptor, family 2, subfamily A, member 12
chr3_+_184018352 0.22 ENST00000435761.1
ENST00000439383.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr18_+_21032781 0.21 ENST00000339486.3
RIO kinase 3
chr5_+_68462837 0.21 ENST00000256442.5
cyclin B1
chr11_-_121986923 0.21 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr11_-_73882057 0.20 ENST00000334126.7
ENST00000313663.7
C2 calcium-dependent domain containing 3
chr4_-_176812842 0.20 ENST00000507540.1
glycoprotein M6A
chr2_+_27760247 0.20 ENST00000447166.1
Uncharacterized protein
chr1_-_160231451 0.19 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr6_-_30080863 0.19 ENST00000540829.1
tripartite motif containing 31
chr1_+_152975488 0.19 ENST00000542696.1
small proline-rich protein 3
chr7_-_55620433 0.19 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr10_-_72542272 0.18 ENST00000545575.1
thymus, brain and testes associated
chr2_+_152266392 0.18 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RAP1 interacting factor homolog (yeast)
chr15_+_36994210 0.18 ENST00000562489.1
chromosome 15 open reading frame 41
chr14_-_105708942 0.17 ENST00000549655.1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr22_+_40573921 0.17 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr5_+_173763250 0.16 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
chr16_-_52061283 0.16 ENST00000566314.1
chromosome 16 open reading frame 97

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.5 3.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 2.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 1.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.7 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 2.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.4 GO:0060539 diaphragm development(GO:0060539)
0.1 1.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 2.1 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 4.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 1.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 4.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 4.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.5 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 1.0 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.1 0.4 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 1.5 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.6 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0046085 purine nucleoside monophosphate catabolic process(GO:0009128) adenosine metabolic process(GO:0046085)
0.1 1.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.7 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.0 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0009304 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 1.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 2.4 GO:1990635 proximal dendrite(GO:1990635)
0.3 0.9 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.2 3.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 4.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.0 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 3.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 2.2 GO:0009986 cell surface(GO:0009986)
0.1 1.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 2.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.8 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 4.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0017129 triglyceride binding(GO:0017129)
0.4 1.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 4.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 3.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.6 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.2 3.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 2.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.4 GO:0070402 NADPH binding(GO:0070402)
0.1 0.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 1.4 GO:0035198 miRNA binding(GO:0035198)
0.0 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK