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Illumina Body Map 2: averaged replicates

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Results for ATF6

Z-value: 1.25

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Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ATF6
ENSG00000118217.5 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_161736093-0.612.4e-04Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_75233563 1.96 ENST00000342232.4
JPH1
junctophilin 1
chr14_+_24600484 1.88 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr1_-_145039949 1.86 ENST00000313382.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_+_35630628 1.74 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_35630926 1.68 ENST00000588081.1
ENST00000589121.1
FXYD1
FXYD domain containing ion transport regulator 1
chr6_-_33714752 1.67 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr11_-_119234876 1.61 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chrX_+_10126488 1.40 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr14_+_105190514 1.39 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr12_+_50497784 1.31 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chrX_-_102941596 1.30 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr1_+_233749739 1.28 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr6_+_29624898 1.28 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
MOG
myelin oligodendrocyte glycoprotein
chr16_-_66959429 1.20 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr11_-_35547151 1.19 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr11_+_113930425 1.18 ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr2_+_155555201 1.15 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr20_+_33292507 1.13 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr19_-_6502341 1.11 ENST00000598006.1
ENST00000601152.1
TUBB4A
tubulin, beta 4A class IVa
chr14_-_35183886 1.10 ENST00000298159.6
CFL2
cofilin 2 (muscle)
chr11_-_35547572 1.09 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr16_+_58535372 1.08 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr10_-_97175444 1.08 ENST00000486141.2
SORBS1
sorbin and SH3 domain containing 1
chr14_-_102976091 1.04 ENST00000286918.4
ANKRD9
ankyrin repeat domain 9
chr11_-_35547277 1.04 ENST00000527605.1
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr3_+_184529948 1.03 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr21_-_38445011 1.01 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_+_184529929 1.01 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chrX_-_102319092 1.00 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr14_-_35183755 1.00 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr12_+_56660633 1.00 ENST00000308197.5
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr7_+_128470431 1.00 ENST00000325888.8
ENST00000346177.6
FLNC
filamin C, gamma
chr18_+_32621324 0.99 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr16_-_70719925 0.96 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr17_-_66951382 0.95 ENST00000586539.1
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr11_+_113930291 0.94 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr21_-_38445470 0.94 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_56661033 0.93 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr17_-_17875688 0.91 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr3_+_50654821 0.91 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr3_-_116164306 0.90 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr17_-_66951474 0.90 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr10_+_121410882 0.89 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr5_-_78809950 0.89 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr12_+_46777450 0.88 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr15_-_75230368 0.88 ENST00000564811.1
ENST00000562233.1
ENST00000567270.1
ENST00000568783.1
COX5A
cytochrome c oxidase subunit Va
chr6_+_29624758 0.88 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
MOG
myelin oligodendrocyte glycoprotein
chr19_+_18723660 0.86 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr17_+_80693427 0.84 ENST00000300784.7
FN3K
fructosamine 3 kinase
chr8_+_9009296 0.84 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr12_+_72148614 0.83 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr6_+_29624862 0.82 ENST00000376894.4
MOG
myelin oligodendrocyte glycoprotein
chr11_+_65292538 0.82 ENST00000270176.5
ENST00000525364.1
ENST00000420247.2
ENST00000533862.1
ENST00000279270.6
ENST00000524944.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr3_-_33759541 0.80 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr19_-_6502590 0.79 ENST00000264071.2
TUBB4A
tubulin, beta 4A class IVa
chr2_-_242211359 0.77 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr5_-_37839782 0.77 ENST00000326524.2
ENST00000515058.1
GDNF
glial cell derived neurotrophic factor
chr19_+_10527449 0.76 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr3_-_33759699 0.76 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2
cytoplasmic linker associated protein 2
chr1_-_113498616 0.75 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr3_+_50654550 0.73 ENST00000430409.1
ENST00000357955.2
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr21_-_38445297 0.72 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_113498943 0.71 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr17_-_27507377 0.70 ENST00000531253.1
MYO18A
myosin XVIIIA
chr17_-_27507395 0.69 ENST00000354329.4
ENST00000527372.1
MYO18A
myosin XVIIIA
chr7_-_35293740 0.69 ENST00000408931.3
TBX20
T-box 20
chr20_-_42815733 0.69 ENST00000342272.3
JPH2
junctophilin 2
chr11_+_112097069 0.68 ENST00000280362.3
ENST00000525803.1
PTS
6-pyruvoyltetrahydropterin synthase
chrX_-_128977364 0.68 ENST00000371064.3
ZDHHC9
zinc finger, DHHC-type containing 9
chr11_+_20409070 0.67 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr11_+_20409227 0.65 ENST00000437750.2
PRMT3
protein arginine methyltransferase 3
chrX_+_122318113 0.64 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr4_+_75310851 0.64 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr7_-_100493744 0.64 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr17_+_66511224 0.64 ENST00000588178.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr22_-_44258280 0.64 ENST00000540422.1
SULT4A1
sulfotransferase family 4A, member 1
chr3_-_24536222 0.64 ENST00000415021.1
ENST00000447875.1
THRB
thyroid hormone receptor, beta
chr14_+_68086515 0.64 ENST00000261783.3
ARG2
arginase 2
chrX_+_122318006 0.63 ENST00000371266.1
ENST00000264357.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chrX_-_128977875 0.63 ENST00000406492.2
ZDHHC9
zinc finger, DHHC-type containing 9
chr22_-_44258360 0.63 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr19_-_6502304 0.61 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
TUBB4A
tubulin, beta 4A class IVa
chr11_+_28131821 0.61 ENST00000379199.2
ENST00000303459.6
METTL15
methyltransferase like 15
chr11_-_75921780 0.61 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr4_+_75311019 0.61 ENST00000502307.1
AREG
amphiregulin
chr9_+_126777676 0.60 ENST00000488674.2
LHX2
LIM homeobox 2
chrX_-_128977781 0.59 ENST00000357166.6
ZDHHC9
zinc finger, DHHC-type containing 9
chr5_-_131562935 0.58 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr2_+_223725723 0.58 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr7_+_44646177 0.57 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_156272924 0.57 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr17_+_66511540 0.57 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_141264597 0.56 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr7_+_116593536 0.56 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr16_-_73082274 0.55 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr7_+_116593433 0.55 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr10_-_118032979 0.54 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr7_+_44646162 0.54 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_24536253 0.54 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr4_-_187647773 0.54 ENST00000509647.1
FAT1
FAT atypical cadherin 1
chr3_-_121468513 0.54 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr3_+_184530173 0.53 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_+_9599540 0.53 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr7_+_116593568 0.53 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr9_+_124461603 0.53 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr10_-_74856608 0.52 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr4_-_169931231 0.52 ENST00000504561.1
CBR4
carbonyl reductase 4
chr1_+_166958497 0.52 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr11_-_77791156 0.51 ENST00000281031.4
NDUFC2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr2_-_193059634 0.51 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr20_-_34638841 0.51 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr4_+_128982416 0.51 ENST00000326639.6
LARP1B
La ribonucleoprotein domain family, member 1B
chr2_-_242255060 0.50 ENST00000413241.1
ENST00000423693.1
ENST00000428482.1
HDLBP
high density lipoprotein binding protein
chr8_+_61429728 0.50 ENST00000529579.1
RAB2A
RAB2A, member RAS oncogene family
chr11_-_59383617 0.50 ENST00000263847.1
OSBP
oxysterol binding protein
chr3_+_148709128 0.50 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1
glycogenin 1
chr9_+_133978190 0.49 ENST00000372312.3
AIF1L
allograft inflammatory factor 1-like
chr2_+_223726281 0.49 ENST00000413316.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr4_-_169931393 0.48 ENST00000504480.1
ENST00000306193.3
CBR4
carbonyl reductase 4
chr7_+_44646218 0.48 ENST00000444676.1
ENST00000222673.5
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr21_-_38445443 0.47 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_+_2269485 0.47 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
OAZ1
ornithine decarboxylase antizyme 1
chr7_+_116593292 0.46 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr11_-_77790865 0.46 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NDUFC2
NDUFC2-KCTD14
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFC2-KCTD14 readthrough
chr12_-_110011288 0.45 ENST00000540016.1
ENST00000266839.5
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr7_+_16793160 0.45 ENST00000262067.4
TSPAN13
tetraspanin 13
chr1_-_193028632 0.45 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr3_+_150264555 0.45 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr19_-_42759266 0.45 ENST00000594664.1
AC006486.9
Uncharacterized protein
chr3_-_121468602 0.44 ENST00000340645.5
GOLGB1
golgin B1
chr3_+_52740094 0.44 ENST00000602728.1
SPCS1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr5_-_132299290 0.44 ENST00000378595.3
AFF4
AF4/FMR2 family, member 4
chr22_-_39548511 0.44 ENST00000434260.1
CBX7
chromobox homolog 7
chr8_+_109455830 0.44 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr1_-_193028621 0.44 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr17_-_57184260 0.43 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr11_-_129149197 0.43 ENST00000525234.1
ARHGAP32
Rho GTPase activating protein 32
chr11_-_67407031 0.43 ENST00000335385.3
TBX10
T-box 10
chr4_-_668108 0.43 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr1_-_20812690 0.42 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_+_65292884 0.42 ENST00000527009.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr20_+_56964169 0.42 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr6_+_127587755 0.41 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr19_-_22715280 0.41 ENST00000593802.1
ZNF98
zinc finger protein 98
chr5_+_63802109 0.41 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr1_-_51425902 0.41 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr11_-_113746212 0.41 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28
ubiquitin specific peptidase 28
chr15_-_72668185 0.41 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA
hexosaminidase A (alpha polypeptide)
chr7_+_128379449 0.41 ENST00000479257.1
CALU
calumenin
chr9_+_35538616 0.40 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr17_+_21730180 0.40 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr17_+_30594823 0.40 ENST00000536287.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr10_-_27444143 0.40 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr1_-_154193091 0.40 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr16_+_14294187 0.40 ENST00000573051.1
MKL2
MKL/myocardin-like 2
chr8_+_94929273 0.39 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_51425772 0.39 ENST00000371778.4
FAF1
Fas (TNFRSF6) associated factor 1
chr4_+_128982490 0.39 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr7_+_72848092 0.39 ENST00000344575.3
FZD9
frizzled family receptor 9
chr2_-_240964716 0.39 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr6_-_151773232 0.38 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr18_-_12377001 0.38 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr1_-_193028426 0.38 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr18_-_46987000 0.38 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr3_+_150264458 0.38 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr1_-_154193009 0.38 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr7_+_92861653 0.37 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
CCDC132
coiled-coil domain containing 132
chr2_-_193059250 0.37 ENST00000409056.3
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr7_+_128379346 0.36 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr9_-_88356789 0.36 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr11_-_118927880 0.36 ENST00000527038.2
HYOU1
hypoxia up-regulated 1
chr18_-_12377283 0.36 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr1_-_94344686 0.36 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr11_-_118927561 0.36 ENST00000530473.1
HYOU1
hypoxia up-regulated 1
chr5_-_41794313 0.36 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr7_-_8302164 0.36 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr4_-_111544254 0.36 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr14_+_76776957 0.35 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr20_+_34042962 0.35 ENST00000446710.1
ENST00000420564.1
CEP250
centrosomal protein 250kDa
chr11_+_28129795 0.35 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr12_-_125398602 0.35 ENST00000541272.1
ENST00000535131.1
UBC
ubiquitin C
chr17_-_57184064 0.35 ENST00000262294.7
TRIM37
tripartite motif containing 37
chrX_+_134478706 0.34 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr6_+_127588020 0.34 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr8_+_94929110 0.34 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_42976736 0.34 ENST00000591382.1
ENST00000593072.1
ENST00000592576.1
ENST00000402521.3
EFTUD2
elongation factor Tu GTP binding domain containing 2
chr16_-_19729453 0.34 ENST00000564480.1
KNOP1
lysine-rich nucleolar protein 1
chr12_-_49412541 0.33 ENST00000547306.1
ENST00000548857.1
ENST00000551696.1
ENST00000316299.5
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr7_-_100808394 0.33 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr2_-_80531824 0.33 ENST00000295057.3
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr12_+_1100423 0.33 ENST00000592048.1
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr11_-_118927735 0.33 ENST00000526656.1
HYOU1
hypoxia up-regulated 1
chr5_-_131563474 0.33 ENST00000417528.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr1_-_160313025 0.33 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr1_+_110527308 0.32 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr4_-_111544207 0.32 ENST00000557119.2
PITX2
paired-like homeodomain 2
chr12_-_49412588 0.32 ENST00000547082.1
ENST00000395170.3
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr11_-_57417405 0.32 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr9_+_100818976 0.32 ENST00000210444.5
NANS
N-acetylneuraminic acid synthase
chr10_+_27793197 0.32 ENST00000356940.6
ENST00000535776.1
RAB18
RAB18, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.4 1.3 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.4 3.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 1.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.3 1.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 1.3 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.3 2.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 0.9 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.3 1.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.3 1.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 1.2 GO:0008050 female courtship behavior(GO:0008050)
0.2 1.4 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
0.2 0.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 2.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.5 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.7 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 1.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 2.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.3 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.8 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 3.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.8 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 0.5 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.6 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 1.5 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.3 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 2.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.0 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 1.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.6 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.5 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.1 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.8 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.2 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.3 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.5 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.7 GO:0000050 urea cycle(GO:0000050)
0.0 0.5 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 2.0 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 1.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.8 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.9 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.9 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0051348 negative regulation of transferase activity(GO:0051348)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 1.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 1.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 1.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.8 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.6 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 2.5 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.3 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.0 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0030849 autosome(GO:0030849)
0.3 2.7 GO:0033263 CORVET complex(GO:0033263)
0.3 1.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 0.7 GO:0005745 m-AAA complex(GO:0005745)
0.2 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.2 3.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 2.6 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.5 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 3.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.6 GO:0045180 basal cortex(GO:0045180)
0.1 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.2 GO:0043034 costamere(GO:0043034)
0.0 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.8 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 2.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.5 1.5 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.5 1.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.4 1.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 1.6 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.3 1.7 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.3 1.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.3 3.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.9 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 1.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 1.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.0 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 2.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 2.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.4 GO:0043531 ADP binding(GO:0043531)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 2.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 1.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.8 GO:0005048 signal sequence binding(GO:0005048)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 2.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism