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Illumina Body Map 2: averaged replicates

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Results for BACH1_NFE2_NFE2L2

Z-value: 3.18

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.11 BACH1
ENSG00000123405.9 NFE2
ENSG00000116044.11 NFE2L2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L2hg19_v2_chr2_-_178128149_178128198-0.584.9e-04Click!
BACH1hg19_v2_chr21_+_30672433_30672464-0.086.8e-01Click!
NFE2hg19_v2_chr12_-_54691668_54691725-0.077.1e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_116840728 8.22 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr16_+_30077055 8.18 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30077098 7.37 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr10_-_76868931 7.31 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr12_+_56075330 7.13 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr18_-_68004529 6.70 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr10_-_76868866 6.56 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr5_+_179247759 5.92 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr3_+_184038234 5.80 ENST00000427607.1
ENST00000457456.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr4_-_987217 5.01 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr5_-_90610200 4.83 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1
RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr17_-_33390667 4.77 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr2_-_220117867 4.56 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr20_-_634000 4.47 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr3_+_184038073 4.37 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_52344416 4.26 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr1_-_45987526 4.14 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
PRDX1
peroxiredoxin 1
chr2_+_54342574 4.13 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr17_+_4853442 3.98 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr6_+_53948328 3.91 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr12_+_10366223 3.79 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_+_160160346 3.77 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chrX_+_153770421 3.75 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr19_-_10613862 3.65 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr6_+_53948221 3.60 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr1_-_52344471 3.54 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr2_-_220083076 3.52 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_160160283 3.51 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_48057890 3.47 ENST00000434267.1
MAP4
microtubule-associated protein 4
chr22_+_21369316 3.40 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr5_-_137911049 3.39 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr8_-_30585294 3.38 ENST00000546342.1
ENST00000541648.1
ENST00000537535.1
GSR
glutathione reductase
chr10_+_115312766 3.37 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr3_+_184037466 3.36 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr20_+_48909240 3.33 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr12_+_10366016 3.20 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr14_+_58711539 3.19 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr3_+_42727011 3.19 ENST00000287777.4
KLHL40
kelch-like family member 40
chr12_+_10365082 3.09 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_+_50706866 3.07 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chrX_+_153769446 3.05 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr10_+_85899196 3.00 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr9_-_86322831 2.99 ENST00000257468.7
UBQLN1
ubiquilin 1
chr11_-_47207390 2.96 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr18_-_55253900 2.96 ENST00000585747.1
ENST00000592699.1
FECH
ferrochelatase
chr11_-_111794446 2.93 ENST00000527950.1
CRYAB
crystallin, alpha B
chr9_-_86323118 2.89 ENST00000376395.4
UBQLN1
ubiquilin 1
chr19_+_18699535 2.88 ENST00000358607.6
C19orf60
chromosome 19 open reading frame 60
chr17_+_30771279 2.83 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_-_86322516 2.82 ENST00000529923.1
UBQLN1
ubiquilin 1
chr10_+_69865866 2.81 ENST00000354393.2
MYPN
myopalladin
chr9_+_92219919 2.80 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr11_+_10477733 2.73 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr3_-_46608010 2.70 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr19_-_10613361 2.69 ENST00000591039.1
ENST00000591419.1
KEAP1
kelch-like ECH-associated protein 1
chr19_-_49658387 2.69 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr2_+_54342533 2.68 ENST00000406041.1
ACYP2
acylphosphatase 2, muscle type
chr10_-_127505167 2.67 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr8_+_123875624 2.65 ENST00000534247.1
ZHX2
zinc fingers and homeoboxes 2
chr16_+_56642041 2.64 ENST00000245185.5
MT2A
metallothionein 2A
chr8_-_30585217 2.63 ENST00000520888.1
ENST00000414019.1
GSR
glutathione reductase
chr16_+_56642489 2.62 ENST00000561491.1
MT2A
metallothionein 2A
chr8_-_30585439 2.56 ENST00000221130.5
GSR
glutathione reductase
chr12_+_10365404 2.56 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_-_10613421 2.53 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr3_+_184016986 2.52 ENST00000417952.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr14_-_23624511 2.52 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr10_-_75423560 2.51 ENST00000606523.1
SYNPO2L
synaptopodin 2-like
chr18_-_55253989 2.48 ENST00000262093.5
FECH
ferrochelatase
chr19_-_49658641 2.48 ENST00000252825.4
HRC
histidine rich calcium binding protein
chr6_-_56819385 2.43 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr12_-_122884553 2.43 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr22_+_20008678 2.41 ENST00000434168.1
TANGO2
transport and golgi organization 2 homolog (Drosophila)
chr3_+_69915363 2.36 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr16_+_74330673 2.36 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_+_156775910 2.29 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr19_+_34850385 2.27 ENST00000587521.2
ENST00000587384.1
ENST00000592277.1
GPI
glucose-6-phosphate isomerase
chr12_-_10151773 2.27 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr22_-_19466454 2.21 ENST00000494054.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr6_+_56819895 2.20 ENST00000370748.3
BEND6
BEN domain containing 6
chr19_+_18699599 2.18 ENST00000450195.2
C19orf60
chromosome 19 open reading frame 60
chr16_-_1429010 2.17 ENST00000513783.1
UNKL
unkempt family zinc finger-like
chr1_-_94374946 2.16 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chrX_+_153769409 2.15 ENST00000440286.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr1_+_214163033 2.14 ENST00000607425.1
PROX1
prospero homeobox 1
chr12_+_6644443 2.13 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr10_+_134901388 2.10 ENST00000392607.3
GPR123
G protein-coupled receptor 123
chr2_+_29353520 2.08 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr6_-_84140757 2.07 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr5_+_150020240 2.06 ENST00000519664.1
SYNPO
synaptopodin
chr3_+_69915385 2.05 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr18_-_55253830 2.04 ENST00000591215.1
FECH
ferrochelatase
chr16_+_83986827 1.98 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr4_+_22999152 1.95 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr6_-_139613269 1.92 ENST00000358430.3
TXLNB
taxilin beta
chr10_-_93392811 1.91 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr21_+_33031935 1.89 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble
chr22_+_20008646 1.86 ENST00000401833.1
TANGO2
transport and golgi organization 2 homolog (Drosophila)
chr8_-_145013711 1.84 ENST00000345136.3
PLEC
plectin
chr1_-_115238207 1.84 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr10_+_106013923 1.80 ENST00000539281.1
GSTO1
glutathione S-transferase omega 1
chr4_+_120056939 1.75 ENST00000307128.5
MYOZ2
myozenin 2
chr22_+_18893736 1.72 ENST00000331444.6
DGCR6
DiGeorge syndrome critical region gene 6
chr3_+_52812523 1.71 ENST00000540715.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr11_+_118958689 1.71 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr7_+_134212312 1.71 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr11_-_14541872 1.68 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr12_+_104680793 1.67 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1
thioredoxin reductase 1
chr2_+_71680852 1.66 ENST00000409762.1
ENST00000409582.3
ENST00000429174.2
ENST00000413539.2
ENST00000258104.3
DYSF
dysferlin
chr1_+_31885963 1.66 ENST00000373709.3
SERINC2
serine incorporator 2
chr20_+_60878005 1.65 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr1_-_109968973 1.65 ENST00000271308.4
ENST00000538610.1
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr2_+_201987200 1.62 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_+_21191341 1.62 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr1_+_76251912 1.61 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr12_-_58026451 1.60 ENST00000552350.1
ENST00000548888.1
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chrX_+_56590002 1.59 ENST00000338222.5
UBQLN2
ubiquilin 2
chr1_+_76251879 1.59 ENST00000535300.1
ENST00000319942.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr6_-_24877490 1.58 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr9_-_35071960 1.58 ENST00000417448.1
VCP
valosin containing protein
chr7_+_130794878 1.57 ENST00000416992.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr2_-_211179883 1.56 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr12_+_57522692 1.56 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr2_-_220119280 1.56 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr22_-_19466683 1.54 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr18_-_55253871 1.53 ENST00000382873.3
FECH
ferrochelatase
chr3_+_100053625 1.53 ENST00000497785.1
NIT2
nitrilase family, member 2
chr7_+_112063192 1.52 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr10_-_76995769 1.51 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr10_-_75173785 1.50 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7
chr19_+_49467232 1.49 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
CTD-2639E6.9
chr2_+_242167319 1.45 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr3_+_100053542 1.44 ENST00000394140.4
NIT2
nitrilase family, member 2
chr18_+_11857439 1.43 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr22_+_18893816 1.40 ENST00000608842.1
DGCR6
DiGeorge syndrome critical region gene 6
chr12_-_58026426 1.40 ENST00000418555.2
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr8_-_42360015 1.39 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr22_-_19466732 1.39 ENST00000263202.10
ENST00000360834.4
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr12_+_104680659 1.38 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr11_-_2924970 1.37 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr1_-_160253998 1.37 ENST00000392220.2
PEX19
peroxisomal biogenesis factor 19
chr2_+_231921574 1.35 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr17_+_18625336 1.35 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L
tripartite motif containing 16-like
chr5_-_171404730 1.34 ENST00000518752.1
FBXW11
F-box and WD repeat domain containing 11
chr8_-_145025044 1.32 ENST00000322810.4
PLEC
plectin
chr11_-_66103867 1.31 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr17_-_79604075 1.30 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr11_-_82746587 1.30 ENST00000528379.1
ENST00000534103.1
RAB30
RAB30, member RAS oncogene family
chr9_-_139922631 1.30 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr10_+_106014468 1.30 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
GSTO1
glutathione S-transferase omega 1
chr7_+_130794846 1.29 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr16_+_22308717 1.29 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr6_-_30899924 1.28 ENST00000359086.3
SFTA2
surfactant associated 2
chr22_-_19466643 1.26 ENST00000474226.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr9_-_73029540 1.25 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr8_+_21914348 1.25 ENST00000520174.1
DMTN
dematin actin binding protein
chr3_-_120365866 1.24 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr16_-_1429627 1.23 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr10_-_76995675 1.22 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr12_-_125401885 1.21 ENST00000542416.1
UBC
ubiquitin C
chr2_+_234959323 1.21 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr7_+_101460882 1.21 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr16_-_1429674 1.20 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like
chr22_-_45608237 1.20 ENST00000492273.1
KIAA0930
KIAA0930
chr7_-_42971759 1.20 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr19_-_59023348 1.20 ENST00000601355.1
ENST00000263093.2
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr8_+_21914477 1.19 ENST00000517804.1
DMTN
dematin actin binding protein
chr6_-_35888858 1.19 ENST00000507909.1
SRPK1
SRSF protein kinase 1
chr22_-_45608324 1.18 ENST00000496226.1
ENST00000251993.7
KIAA0930
KIAA0930
chr4_+_87928353 1.18 ENST00000511722.1
AFF1
AF4/FMR2 family, member 1
chr11_+_62649158 1.15 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr6_-_31745085 1.14 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr10_+_121410882 1.13 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr17_+_7123207 1.13 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr9_-_26946981 1.12 ENST00000523212.1
PLAA
phospholipase A2-activating protein
chr18_+_3252206 1.12 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_+_120315149 1.11 ENST00000184266.2
NDUFB4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr16_+_89168993 1.11 ENST00000538340.1
ENST00000543676.1
ACSF3
acyl-CoA synthetase family member 3
chr16_+_8736232 1.10 ENST00000562973.1
METTL22
methyltransferase like 22
chr7_+_150434430 1.09 ENST00000358647.3
GIMAP5
GTPase, IMAP family member 5
chr4_+_87928413 1.09 ENST00000544085.1
AFF1
AF4/FMR2 family, member 1
chr16_+_89168753 1.09 ENST00000544543.1
ACSF3
acyl-CoA synthetase family member 3
chr12_-_125399573 1.08 ENST00000339647.5
UBC
ubiquitin C
chr6_-_39902185 1.08 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
MOCS1
molybdenum cofactor synthesis 1
chr1_-_113478603 1.08 ENST00000443580.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr17_+_16284399 1.07 ENST00000535788.1
UBB
ubiquitin B
chr12_-_122238464 1.07 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr6_-_39902160 1.05 ENST00000340692.5
MOCS1
molybdenum cofactor synthesis 1
chr14_-_23504087 1.05 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr10_-_71892555 1.04 ENST00000307864.1
AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr3_+_120315160 1.04 ENST00000485064.1
ENST00000492739.1
NDUFB4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr9_-_134615326 1.04 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr2_+_173955327 1.02 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr17_+_16284104 1.01 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr17_+_18086392 1.00 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr18_+_3252265 1.00 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_160231451 1.00 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr16_-_15180257 1.00 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr3_+_183903811 0.99 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr3_-_81792780 0.99 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
1.7 5.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.5 9.0 GO:0070541 response to platinum ion(GO:0070541)
1.1 5.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.9 13.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.9 2.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.8 3.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.8 10.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.8 15.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 4.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 2.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.7 2.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.7 2.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.6 1.8 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.6 8.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.6 13.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6 2.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.6 1.7 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.5 2.2 GO:0090410 malonate catabolic process(GO:0090410)
0.5 2.2 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.5 1.6 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.5 8.2 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5 1.5 GO:0007518 myoblast fate determination(GO:0007518)
0.5 3.5 GO:0051012 microtubule sliding(GO:0051012)
0.5 3.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.5 2.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.4 4.5 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 2.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 4.6 GO:0032264 IMP salvage(GO:0032264)
0.4 2.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 1.6 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.4 1.5 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.4 1.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 5.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 2.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 3.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 5.7 GO:0043248 proteasome assembly(GO:0043248)
0.3 8.0 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 0.9 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.3 2.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 2.0 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 1.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.3 0.8 GO:0003032 detection of oxygen(GO:0003032)
0.3 1.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 3.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.3 30.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.2 2.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.7 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2 0.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.9 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 3.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.9 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 2.9 GO:0030259 lipid glycosylation(GO:0030259)
0.2 1.0 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 2.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 0.6 GO:0060931 sinoatrial node cell development(GO:0060931)
0.2 3.5 GO:0015886 heme transport(GO:0015886)
0.2 1.3 GO:0051414 response to cortisol(GO:0051414)
0.2 1.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 1.2 GO:0060356 leucine import(GO:0060356)
0.2 1.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.7 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 3.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 3.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 0.3 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.2 0.6 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 14.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 3.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 1.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 2.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.8 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 2.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 1.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 2.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.7 GO:0001778 plasma membrane repair(GO:0001778)
0.1 4.0 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.8 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442) regulation of stem cell division(GO:2000035)
0.1 1.4 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.5 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.8 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 4.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 3.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.6 GO:0072675 osteoclast fusion(GO:0072675)
0.1 1.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 3.6 GO:0033198 response to ATP(GO:0033198)
0.1 4.0 GO:0043486 histone exchange(GO:0043486)
0.1 0.9 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 13.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.5 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 2.5 GO:0015695 organic cation transport(GO:0015695)
0.1 2.3 GO:0030220 platelet formation(GO:0030220)
0.1 0.2 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0030239 myofibril assembly(GO:0030239)
0.1 1.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.7 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 1.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.3 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.5 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.5 GO:0009651 response to salt stress(GO:0009651)
0.0 1.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.0 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 1.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 7.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 1.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.8 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 2.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.5 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 10.2 GO:0032259 methylation(GO:0032259)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.9 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 2.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.4 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 1.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0098743 cell aggregation(GO:0098743)
0.0 0.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.5 5.9 GO:0044753 amphisome(GO:0044753)
1.3 3.9 GO:0034515 proteasome storage granule(GO:0034515)
0.9 7.3 GO:0014802 terminal cisterna(GO:0014802)
0.8 2.4 GO:0097444 spine apparatus(GO:0097444)
0.8 9.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.7 2.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.7 2.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.6 3.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6 6.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5 2.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.5 3.1 GO:0097513 myosin II filament(GO:0097513)
0.5 13.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 4.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 2.4 GO:0031673 H zone(GO:0031673)
0.4 9.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 5.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 14.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 5.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 5.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.3 19.2 GO:0031430 M band(GO:0031430)
0.3 2.1 GO:0097452 GAIT complex(GO:0097452)
0.3 1.6 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 2.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 0.6 GO:0005745 m-AAA complex(GO:0005745)
0.2 3.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 11.7 GO:0000502 proteasome complex(GO:0000502)
0.1 0.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 3.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.2 GO:0031672 A band(GO:0031672)
0.1 3.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 4.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 2.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 9.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.6 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 3.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 8.7 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 7.6 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 2.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 2.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 4.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 19.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 5.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.7 GO:0030315 T-tubule(GO:0030315)
0.0 1.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 7.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 4.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 2.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 6.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.8 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.0 GO:0004325 ferrochelatase activity(GO:0004325)
2.1 8.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
2.1 8.2 GO:0019862 IgA binding(GO:0019862)
1.8 9.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
1.3 15.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.2 7.0 GO:0003998 acylphosphatase activity(GO:0003998)
1.2 3.5 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.9 2.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.7 2.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.7 2.8 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.7 12.6 GO:0030957 Tat protein binding(GO:0030957)
0.6 3.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.6 1.8 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.6 3.0 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.6 1.7 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.5 2.2 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.5 13.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 2.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.5 3.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.5 2.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 3.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.5 1.5 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.5 4.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 2.3 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.4 4.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 4.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 1.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.4 2.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.4 1.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.3 1.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 11.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 1.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.3 5.3 GO:0046870 cadmium ion binding(GO:0046870)
0.3 1.6 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.3 1.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 0.9 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 2.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.7 GO:0051373 FATZ binding(GO:0051373)
0.3 1.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.3 3.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 0.8 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 0.8 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.3 0.8 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.3 2.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 0.7 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 0.7 GO:0097689 iron channel activity(GO:0097689)
0.2 2.1 GO:0050692 DBD domain binding(GO:0050692)
0.2 4.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 3.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 2.5 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 14.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 1.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 13.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 1.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.8 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 2.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 5.5 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1 3.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0070026 nitric oxide binding(GO:0070026)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 4.6 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 3.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.2 GO:0034618 arginine binding(GO:0034618)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 2.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 4.8 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 5.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 2.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 5.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 8.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328) sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 15.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 3.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 7.0 GO:0005525 GTP binding(GO:0005525)
0.0 1.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 23.6 PID TNF PATHWAY TNF receptor signaling pathway
0.2 24.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 15.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 10.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.0 PID EPO PATHWAY EPO signaling pathway
0.0 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 3.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 3.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 9.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 5.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.5 13.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.5 9.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 13.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 23.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 25.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3 11.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 6.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 4.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 7.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 4.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 3.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 4.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 8.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+