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Illumina Body Map 2: averaged replicates

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Results for BACH2

Z-value: 1.10

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.10 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006461_910065170.346.0e-02Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_95010147 2.07 ENST00000548918.1
transmembrane and coiled-coil domain family 3
chr16_+_30077098 1.91 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr2_-_220173685 1.85 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr16_+_30077055 1.72 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr12_-_95009837 1.66 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr2_+_169926047 1.46 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr12_+_7023735 1.46 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr1_+_36621174 1.44 ENST00000429533.2
MAP7 domain containing 1
chr17_-_7123021 1.41 ENST00000399510.2
discs, large homolog 4 (Drosophila)
chr12_+_7023491 1.35 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr4_+_74606223 1.27 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr3_+_187930491 1.26 ENST00000443217.1
LIM domain containing preferred translocation partner in lipoma
chr3_-_71834207 1.26 ENST00000295619.3
prokineticin 2
chr3_-_98241598 1.20 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
claudin domain containing 1
chr1_+_36621529 1.17 ENST00000316156.4
MAP7 domain containing 1
chr8_+_22844995 1.16 ENST00000524077.1
Rho-related BTB domain containing 2
chr5_-_176923846 1.15 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr5_+_175288631 1.14 ENST00000509837.1
complexin 2
chr10_+_88428206 1.13 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr1_+_154378049 1.08 ENST00000512471.1
interleukin 6 receptor
chr3_+_35685113 1.07 ENST00000419330.1
cAMP-regulated phosphoprotein, 21kDa
chr5_-_176923803 1.06 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr13_-_36429763 1.06 ENST00000379893.1
doublecortin-like kinase 1
chr12_-_76478686 1.04 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr11_-_66104237 1.04 ENST00000530056.1
Ras and Rab interactor 1
chr1_+_36621697 1.03 ENST00000373150.4
ENST00000373151.2
MAP7 domain containing 1
chr12_-_71182695 1.02 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr6_-_24877490 1.01 ENST00000540914.1
ENST00000378023.4
family with sequence similarity 65, member B
chr1_+_154377669 1.01 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr1_-_40157345 0.99 ENST00000372844.3
hippocalcin like 4
chr11_-_62457371 0.99 ENST00000317449.4
LRRN4 C-terminal like
chr20_+_44034804 0.96 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_-_18995029 0.96 ENST00000596048.1
ceramide synthase 1
chr5_+_169758393 0.95 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
chr11_+_10476851 0.95 ENST00000396553.2
adenosine monophosphate deaminase 3
chr9_-_114246332 0.94 ENST00000602978.1
KIAA0368
chr19_+_38794797 0.94 ENST00000301246.5
ENST00000588605.1
chromosome 19 open reading frame 33
chr22_+_42372764 0.93 ENST00000396426.3
ENST00000406029.1
septin 3
chr15_+_51633826 0.91 ENST00000335449.6
gliomedin
chr11_+_10477733 0.91 ENST00000528723.1
adenosine monophosphate deaminase 3
chr3_+_11178779 0.91 ENST00000438284.2
histamine receptor H1
chr16_+_89988259 0.90 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr19_+_10959043 0.89 ENST00000397820.4
chromosome 19 open reading frame 38
chr8_+_22844913 0.89 ENST00000519685.1
Rho-related BTB domain containing 2
chr11_-_66103932 0.89 ENST00000311320.4
Ras and Rab interactor 1
chr18_+_32290218 0.88 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr6_+_56819895 0.87 ENST00000370748.3
BEN domain containing 6
chr21_+_30672433 0.87 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_+_22766766 0.86 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr22_+_42372931 0.86 ENST00000328414.8
ENST00000396425.3
septin 3
chr3_+_187930429 0.86 ENST00000420410.1
LIM domain containing preferred translocation partner in lipoma
chr10_+_88428370 0.85 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LIM domain binding 3
chr5_-_41794663 0.83 ENST00000510634.1
3-oxoacid CoA transferase 1
chr17_-_18161870 0.81 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr3_-_98241358 0.80 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr16_+_58533951 0.79 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG family member 4
chr11_-_66103867 0.78 ENST00000424433.2
Ras and Rab interactor 1
chr5_+_150020240 0.78 ENST00000519664.1
synaptopodin
chr12_-_719573 0.78 ENST00000397265.3
ninjurin 2
chr17_-_27503770 0.78 ENST00000533112.1
myosin XVIIIA
chr2_-_219858123 0.77 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
crystallin, beta A2
chr11_-_62323702 0.77 ENST00000530285.1
AHNAK nucleoprotein
chr3_+_48507621 0.76 ENST00000456089.1
three prime repair exonuclease 1
chr11_+_57308979 0.75 ENST00000457912.1
smoothelin-like 1
chr9_-_35112376 0.75 ENST00000488109.2
family with sequence similarity 214, member B
chr5_+_176237478 0.74 ENST00000329542.4
unc-5 homolog A (C. elegans)
chr10_+_104155450 0.73 ENST00000471698.1
ENST00000189444.6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_-_158656488 0.72 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr5_+_110559603 0.72 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr9_-_114246635 0.72 ENST00000338205.5
KIAA0368
chr17_+_79651007 0.71 ENST00000572392.1
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr17_-_70417365 0.71 ENST00000580948.1
long intergenic non-protein coding RNA 511
chr5_-_41794313 0.70 ENST00000512084.1
3-oxoacid CoA transferase 1
chr3_-_187454281 0.70 ENST00000232014.4
B-cell CLL/lymphoma 6
chr3_-_71834318 0.69 ENST00000353065.3
prokineticin 2
chr8_+_123875624 0.68 ENST00000534247.1
zinc fingers and homeoboxes 2
chr14_+_77425972 0.68 ENST00000553613.1
RP11-7F17.7
chr3_-_98241713 0.67 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
claudin domain containing 1
chr8_+_24771265 0.67 ENST00000518131.1
ENST00000437366.2
neurofilament, medium polypeptide
chr3_-_131756559 0.67 ENST00000505957.1
copine IV
chr6_+_74405501 0.64 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr22_+_42372970 0.64 ENST00000291236.11
septin 3
chr1_-_179112189 0.64 ENST00000512653.1
ENST00000344730.3
c-abl oncogene 2, non-receptor tyrosine kinase
chr10_+_86088337 0.64 ENST00000359979.4
coiled-coil serine-rich protein 2
chr1_+_223889285 0.63 ENST00000433674.2
calpain 2, (m/II) large subunit
chr6_+_74405804 0.63 ENST00000287097.5
CD109 molecule
chr16_+_15596123 0.62 ENST00000452191.2
chromosome 16 open reading frame 45
chr6_-_119031228 0.62 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr15_-_83316087 0.61 ENST00000568757.1
cytoplasmic polyadenylation element binding protein 1
chr12_-_118490217 0.61 ENST00000542304.1
WD repeat and SOCS box containing 2
chr12_-_6809958 0.61 ENST00000320591.5
ENST00000534837.1
PILR alpha associated neural protein
chr8_-_68658578 0.61 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
carboxypeptidase A6
chr19_-_6057282 0.61 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr11_-_128894053 0.60 ENST00000392657.3
Rho GTPase activating protein 32
chr4_-_100356551 0.60 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_113698946 0.59 ENST00000397021.1
MCF.2 cell line derived transforming sequence-like
chr3_+_69134080 0.58 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr6_+_44214824 0.58 ENST00000371646.5
ENST00000353801.3
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr12_-_76478446 0.57 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr3_+_164924716 0.57 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
chr3_+_48507210 0.57 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr12_-_118490403 0.56 ENST00000535496.1
WD repeat and SOCS box containing 2
chr19_+_36630855 0.55 ENST00000589146.1
calpain, small subunit 1
chr17_+_65375082 0.55 ENST00000584471.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_68685764 0.54 ENST00000361320.4
leucine rich repeat transmembrane neuronal 3
chr7_+_143078379 0.54 ENST00000449630.1
ENST00000457235.1
zyxin
chr3_+_69134124 0.54 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr5_+_110559784 0.53 ENST00000282356.4
calcium/calmodulin-dependent protein kinase IV
chr12_+_10365082 0.52 ENST00000545859.1
GABA(A) receptor-associated protein like 1
chr12_-_76478386 0.52 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr15_-_72521017 0.52 ENST00000561609.1
pyruvate kinase, muscle
chr12_-_76478417 0.52 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr17_+_79650962 0.51 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr22_+_20861858 0.51 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr1_-_235116495 0.51 ENST00000549744.1
RP11-443B7.3
chr17_+_25799008 0.51 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr7_-_15014398 0.50 ENST00000437998.1
diacylglycerol kinase, beta 90kDa
chr9_-_34662651 0.50 ENST00000259631.4
chemokine (C-C motif) ligand 27
chr6_-_56819385 0.50 ENST00000370754.5
ENST00000449297.2
dystonin
chr4_-_100356844 0.50 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_113699029 0.49 ENST00000423251.1
MCF.2 cell line derived transforming sequence-like
chr6_+_56820018 0.49 ENST00000370746.3
BEN domain containing 6
chr10_+_86088381 0.49 ENST00000224756.8
ENST00000372088.2
coiled-coil serine-rich protein 2
chr2_+_87754989 0.49 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr3_+_164924769 0.49 ENST00000494915.1
RP11-85M11.2
chr2_+_69201705 0.49 ENST00000377938.2
gastrokine 1
chr9_-_139922726 0.49 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr15_+_89182178 0.49 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr2_-_145275109 0.48 ENST00000431672.2
zinc finger E-box binding homeobox 2
chr12_+_64846129 0.47 ENST00000540417.1
ENST00000539810.1
TANK-binding kinase 1
chr14_-_25103388 0.47 ENST00000526004.1
ENST00000415355.3
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chrX_-_129244336 0.47 ENST00000434609.1
E74-like factor 4 (ets domain transcription factor)
chr1_-_156675368 0.47 ENST00000368222.3
cellular retinoic acid binding protein 2
chr15_+_75335604 0.47 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr17_-_76921459 0.46 ENST00000262768.7
TIMP metallopeptidase inhibitor 2
chrX_-_20074895 0.46 ENST00000543767.1
MAP7 domain containing 2
chr5_+_110559312 0.45 ENST00000508074.1
calcium/calmodulin-dependent protein kinase IV
chr3_+_184534994 0.45 ENST00000441141.1
ENST00000445089.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chrX_+_150863951 0.45 ENST00000370354.1
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr19_-_36019123 0.44 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr19_+_38880695 0.44 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr3_+_174158732 0.42 ENST00000434257.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chr22_+_20862321 0.42 ENST00000541476.1
ENST00000438962.1
mediator complex subunit 15
chr1_+_223889310 0.42 ENST00000434648.1
calpain 2, (m/II) large subunit
chr19_+_36630961 0.41 ENST00000587718.1
ENST00000592483.1
ENST00000590874.1
ENST00000588815.1
calpain, small subunit 1
chr11_-_46848393 0.41 ENST00000526496.1
cytoskeleton associated protein 5
chr6_-_113953705 0.40 ENST00000452675.1
RP11-367G18.1
chr19_+_36630454 0.40 ENST00000246533.3
calpain, small subunit 1
chr1_-_223853425 0.40 ENST00000366873.2
ENST00000419193.2
calpain 8
chr12_+_64845864 0.40 ENST00000538890.1
TANK-binding kinase 1
chr2_+_87754887 0.40 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr12_+_6644443 0.40 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_27816641 0.40 ENST00000430629.2
WAS protein family, member 2
chr6_+_44215603 0.39 ENST00000371554.1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr21_+_30671690 0.39 ENST00000399921.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrY_+_15016725 0.39 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr9_+_34992846 0.39 ENST00000443266.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr14_+_22989368 0.39 ENST00000390514.1
T cell receptor alpha joining 23
chr5_+_179247759 0.39 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr11_-_65667997 0.38 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr6_+_56819773 0.38 ENST00000370750.2
BEN domain containing 6
chr4_+_123747834 0.38 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr10_+_17270214 0.38 ENST00000544301.1
vimentin
chr7_-_98467543 0.37 ENST00000345589.4
transmembrane protein 130
chr2_+_36923830 0.37 ENST00000379242.3
ENST00000389975.3
vitrin
chr17_+_30469579 0.37 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr14_-_23426322 0.37 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr14_-_25103472 0.37 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr11_-_65667884 0.36 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr2_-_220117867 0.36 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr16_-_89043377 0.36 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr3_+_184016986 0.36 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr2_-_145275211 0.36 ENST00000462355.1
zinc finger E-box binding homeobox 2
chr1_-_52344416 0.36 ENST00000544028.1
nardilysin (N-arginine dibasic convertase)
chr15_+_89182156 0.35 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr1_-_6662919 0.35 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr14_-_23426337 0.35 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr16_+_30418910 0.35 ENST00000566625.1
zinc finger protein 771
chr14_-_23426270 0.35 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr17_+_30469473 0.35 ENST00000333942.6
ENST00000358365.3
ENST00000583994.1
ENST00000545287.2
ras homolog family member T1
chr19_+_49467232 0.34 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr2_+_231921574 0.34 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr4_-_100356291 0.34 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr15_+_38988799 0.34 ENST00000318792.1
chromosome 15 open reading frame 53
chr19_+_6740888 0.33 ENST00000596673.1
thyroid hormone receptor interactor 10
chrX_-_129244454 0.33 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr14_-_51863853 0.33 ENST00000556762.1
RP11-255G12.3
chr10_-_23003460 0.33 ENST00000376573.4
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr4_+_123747979 0.33 ENST00000608478.1
fibroblast growth factor 2 (basic)
chrX_-_129244655 0.33 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr10_-_31288398 0.32 ENST00000538351.2
zinc finger protein 438
chr14_+_105147464 0.32 ENST00000540171.2
RP11-982M15.6
chr11_-_47206965 0.32 ENST00000525725.1
protein kinase C and casein kinase substrate in neurons 3
chr1_+_152881014 0.32 ENST00000368764.3
ENST00000392667.2
involucrin
chr9_-_139922631 0.32 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_46316677 0.31 ENST00000534787.1
cAMP responsive element binding protein 3-like 1
chr17_-_48785216 0.31 ENST00000285243.6
ankyrin repeat domain 40
chr10_-_73611046 0.31 ENST00000394934.1
ENST00000394936.3
prosaposin
chr11_+_59522837 0.31 ENST00000437946.2
syntaxin 3
chr7_-_98467629 0.31 ENST00000339375.4
transmembrane protein 130

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0002384 hepatic immune response(GO:0002384)
0.6 1.7 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.5 1.8 GO:1990502 dense core granule maturation(GO:1990502)
0.4 1.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 1.0 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.3 1.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3 2.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.9 GO:0006196 AMP catabolic process(GO:0006196)
0.3 1.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 1.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 0.7 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.2 0.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 3.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.7 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.7 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 1.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 1.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.7 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.1 0.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.8 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.4 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.5 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.2 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.1 0.5 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.7 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 1.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 1.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.7 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.8 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.0 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 1.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0051582 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 1.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 2.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0006986 response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:2001171 sequestering of actin monomers(GO:0042989) positive regulation of ATP biosynthetic process(GO:2001171)
0.0 1.6 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.7 GO:0034515 proteasome storage granule(GO:0034515)
0.2 0.7 GO:0097444 spine apparatus(GO:0097444)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.5 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.1 3.3 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0070652 HAUS complex(GO:0070652)
0.1 0.9 GO:0032437 cuticular plate(GO:0032437)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 4.4 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 4.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 3.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.0 GO:0043204 perikaryon(GO:0043204)
0.0 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.4 1.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.4 1.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 3.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.0 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.2 1.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.7 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.9 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL