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Illumina Body Map 2: averaged replicates
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Results for BARHL1
Z-value: 3.07
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Transcription factors associated with BARHL1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BARHL1 | hg19_v2_chr9_+_135458021_135458046 | -0.37 | 3.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_29171689 Show fit | 4.97 |
ENST00000237014.3
|
transthyretin |
|
| chr8_+_1993152 Show fit | 4.18 |
ENST00000262113.4
|
myomesin 2 |
|
| chr3_+_63428982 Show fit | 3.84 |
ENST00000479198.1
ENST00000460711.1 ENST00000465156.1 |
synaptoporin |
|
| chr14_+_32798462 Show fit | 3.77 |
ENST00000280979.4
|
A kinase (PRKA) anchor protein 6 |
|
| chr13_-_114107839 Show fit | 3.76 |
ENST00000375418.3
|
ADP-ribosylhydrolase like 1 |
|
| chr5_+_140593509 Show fit | 3.65 |
ENST00000341948.4
|
protocadherin beta 13 |
|
| chr13_+_30002741 Show fit | 3.61 |
ENST00000380808.2
|
microtubule associated tumor suppressor candidate 2 |
|
| chr11_+_27076764 Show fit | 3.46 |
ENST00000525090.1
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
|
| chr14_+_32798547 Show fit | 3.46 |
ENST00000557354.1
ENST00000557102.1 ENST00000557272.1 |
A kinase (PRKA) anchor protein 6 |
|
| chr8_+_1993173 Show fit | 3.44 |
ENST00000523438.1
|
myomesin 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of BARHL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 30.6 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 20.5 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.2 | 15.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 14.1 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.3 | 12.1 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.9 | 11.5 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.3 | 11.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 1.3 | 10.1 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.4 | 9.9 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 1.0 | 9.5 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 59.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 27.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 27.6 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 17.6 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 15.6 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 15.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.2 | 15.2 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.8 | 13.8 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 11.2 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.3 | 11.1 | GO:0032982 | myosin filament(GO:0032982) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 30.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.7 | 22.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 20.3 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 18.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.2 | 15.0 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 13.9 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.3 | 13.5 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.6 | 12.8 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 12.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.5 | 11.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 12.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 9.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 6.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 4.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 4.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 4.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 4.3 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 3.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.1 | 3.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 14.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.4 | 13.2 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 12.7 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 11.1 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 9.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.2 | 9.0 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 7.6 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 7.5 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.1 | 6.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |