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Illumina Body Map 2: averaged replicates
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Results for BARX1
Z-value: 2.11
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Transcription factors associated with BARX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BARX1 | hg19_v2_chr9_-_96717654_96717666 | 0.52 | 2.4e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_150404904 Show fit | 4.97 |
ENST00000521632.1
|
glutathione peroxidase 3 (plasma) |
|
| chr4_+_119810134 Show fit | 4.73 |
ENST00000434046.2
|
synaptopodin 2 |
|
| chr3_-_172859017 Show fit | 4.62 |
ENST00000351008.3
|
spermatogenesis associated 16 |
|
| chr8_-_124749609 Show fit | 4.42 |
ENST00000262219.6
ENST00000419625.1 |
annexin A13 |
|
| chr7_-_16921601 Show fit | 4.39 |
ENST00000402239.3
ENST00000310398.2 ENST00000414935.1 |
anterior gradient 3 |
|
| chr4_-_177162822 Show fit | 4.15 |
ENST00000512254.1
|
ankyrin repeat and SOCS box containing 5 |
|
| chr4_+_119809984 Show fit | 3.91 |
ENST00000307142.4
ENST00000448416.2 ENST00000429713.2 |
synaptopodin 2 |
|
| chr5_+_127039075 Show fit | 3.65 |
ENST00000514853.2
|
CTC-228N24.1 |
|
| chr12_-_71551652 Show fit | 3.62 |
ENST00000546561.1
|
tetraspanin 8 |
|
| chr9_-_95166976 Show fit | 3.59 |
ENST00000447356.1
|
osteoglycin |
Network of associatons between targets according to the STRING database.
First level regulatory network of BARX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.3 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 10.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.4 | 9.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 8.6 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 0.4 | 8.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 7.5 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.5 | 6.7 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 6.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.4 | 5.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 5.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 9.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 9.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 6.8 | GO:0032982 | myosin filament(GO:0032982) |
| 0.7 | 5.8 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.2 | 5.8 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.4 | 5.7 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.2 | 5.6 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 4.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 4.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 22.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 15.9 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 13.3 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 7.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.2 | 7.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 6.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 5.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 5.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 1.1 | 5.6 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.2 | 5.0 | GO:0008430 | selenium binding(GO:0008430) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 20.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 8.0 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 4.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 4.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.5 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 3.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 2.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 2.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.4 | 9.4 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 9.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 7.0 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.2 | 5.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 4.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 3.9 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 3.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 3.6 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 3.6 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |