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Illumina Body Map 2: averaged replicates

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Results for BBX

Z-value: 1.48

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Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
BBX
ENSG00000114439.14 BBX high mobility group box domain containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BBXhg19_v2_chr3_+_107241882_107241904-0.232.1e-01Click!

Activity profile of BBX motif

Sorted Z-values of BBX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 9.75 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 9.63 ENST00000302068.4
FGB
fibrinogen beta chain
chr9_-_116837249 5.88 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr6_-_25874440 4.27 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr6_-_107235331 3.58 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr3_+_81043000 3.55 ENST00000482617.1
RP11-6B4.1
RP11-6B4.1
chr20_-_7921090 3.12 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr7_+_117120106 2.96 ENST00000426809.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr6_-_107235287 2.86 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr8_-_28347737 2.45 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr16_+_56672571 2.41 ENST00000290705.8
MT1A
metallothionein 1A
chr7_+_117120017 2.22 ENST00000003084.6
ENST00000454343.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr2_+_102928009 1.95 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr7_+_128349106 1.87 ENST00000485070.1
FAM71F1
family with sequence similarity 71, member F1
chr4_-_70080449 1.70 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr2_+_197577841 1.66 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr7_-_16872932 1.63 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr19_+_49109990 1.62 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chr11_+_22689648 1.58 ENST00000278187.3
GAS2
growth arrest-specific 2
chr19_+_7828035 1.57 ENST00000327325.5
ENST00000394122.2
ENST00000248228.4
ENST00000334806.5
ENST00000359059.5
ENST00000357361.2
ENST00000596363.1
ENST00000595751.1
ENST00000596707.1
ENST00000597522.1
ENST00000595496.1
CLEC4M
C-type lectin domain family 4, member M
chr13_+_76413852 1.56 ENST00000533809.2
LMO7
LIM domain 7
chr6_-_107235378 1.46 ENST00000606430.1
RP1-60O19.1
RP1-60O19.1
chr12_-_100656134 1.35 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr4_+_88571429 1.35 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr7_-_121944491 1.35 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr4_-_186696425 1.29 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr11_+_60467142 1.27 ENST00000529752.1
MS4A8
membrane-spanning 4-domains, subfamily A, member 8
chr6_+_31895254 1.27 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr6_+_31895287 1.26 ENST00000447952.2
C2
complement component 2
chr6_-_161085291 1.23 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr1_-_198509804 1.21 ENST00000489986.1
ENST00000367382.1
ATP6V1G3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr4_-_104021009 1.17 ENST00000509245.1
ENST00000296424.4
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr12_-_21487829 1.17 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr11_-_62997124 1.10 ENST00000306494.6
SLC22A25
solute carrier family 22, member 25
chr4_-_186696561 1.09 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr9_+_35161998 1.09 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr4_-_186733363 1.09 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr14_+_38264418 1.07 ENST00000267368.7
ENST00000382320.3
TTC6
tetratricopeptide repeat domain 6
chrX_-_140786896 1.06 ENST00000370515.3
SPANXD
SPANX family, member D
chr11_+_60467047 1.04 ENST00000300226.2
MS4A8
membrane-spanning 4-domains, subfamily A, member 8
chr4_-_186696515 1.03 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_59043166 1.01 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr14_+_67656110 1.01 ENST00000524532.1
ENST00000530728.1
FAM71D
family with sequence similarity 71, member D
chr4_-_104020968 1.01 ENST00000504285.1
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr17_+_40950900 0.98 ENST00000588527.1
CNTD1
cyclin N-terminal domain containing 1
chr2_+_101437487 0.98 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chrX_-_52827141 0.98 ENST00000375511.3
SPANXN5
SPANX family, member N5
chr4_-_987217 0.95 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr4_-_186734275 0.94 ENST00000456060.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_94492674 0.91 ENST00000203664.5
ENST00000553723.1
OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr21_+_31768348 0.90 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr4_-_186696636 0.86 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_135818368 0.82 ENST00000367798.2
AHI1
Abelson helper integration site 1
chr16_-_58768177 0.81 ENST00000434819.2
ENST00000245206.5
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial
chr22_+_44319619 0.80 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr10_-_94003003 0.80 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_39734783 0.79 ENST00000552961.1
KIF21A
kinesin family member 21A
chr3_+_94657016 0.79 ENST00000462219.1
LINC00879
long intergenic non-protein coding RNA 879
chr19_+_9361606 0.79 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr3_+_51851612 0.78 ENST00000456080.1
IQCF3
IQ motif containing F3
chr4_+_174818390 0.76 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr13_+_28494130 0.73 ENST00000381033.4
PDX1
pancreatic and duodenal homeobox 1
chr4_-_186697044 0.71 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr2_+_78143006 0.71 ENST00000443419.1
AC073628.1
AC073628.1
chr1_+_51567895 0.71 ENST00000371759.2
C1orf185
chromosome 1 open reading frame 185
chr2_+_228735763 0.71 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chrX_+_140677562 0.70 ENST00000370518.3
SPANXA2
SPANX family, member A2
chr15_+_65823092 0.68 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_94657118 0.67 ENST00000466089.1
ENST00000470465.1
LINC00879
long intergenic non-protein coding RNA 879
chr2_+_102927962 0.65 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr1_+_170115142 0.64 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr6_-_88001706 0.64 ENST00000369576.2
GJB7
gap junction protein, beta 7, 25kDa
chr16_-_31564881 0.63 ENST00000567765.1
CTD-2014E2.6
CTD-2014E2.6
chr2_+_232135245 0.63 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr3_+_177534653 0.63 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr1_+_51567910 0.62 ENST00000467127.1
C1orf185
chromosome 1 open reading frame 185
chr7_-_16921601 0.59 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3
anterior gradient 3
chr18_-_56985873 0.57 ENST00000299721.3
CPLX4
complexin 4
chr2_+_179149636 0.57 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr9_-_95166841 0.56 ENST00000262551.4
OGN
osteoglycin
chr19_+_31658405 0.56 ENST00000589511.1
CTC-439O9.3
CTC-439O9.3
chr12_-_4754356 0.54 ENST00000540967.1
AKAP3
A kinase (PRKA) anchor protein 3
chr3_+_130159354 0.53 ENST00000373157.4
COL6A5
collagen, type VI, alpha 5
chr12_-_4754339 0.53 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr17_-_16256718 0.53 ENST00000476243.1
ENST00000299736.4
CENPV
centromere protein V
chr6_+_54173227 0.53 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr12_-_4754318 0.53 ENST00000536414.1
AKAP3
A kinase (PRKA) anchor protein 3
chr6_-_50016364 0.52 ENST00000322246.4
DEFB112
defensin, beta 112
chr3_+_94657086 0.51 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chr1_-_153123345 0.50 ENST00000368748.4
SPRR2G
small proline-rich protein 2G
chr9_-_95166884 0.50 ENST00000375561.5
OGN
osteoglycin
chr6_-_49712123 0.49 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr1_+_55464600 0.48 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr1_+_95616933 0.48 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr13_-_81801115 0.47 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chrX_+_144328348 0.47 ENST00000370493.3
SPANXN1
SPANX family, member N1
chr8_-_6783588 0.47 ENST00000297436.2
DEFA6
defensin, alpha 6, Paneth cell-specific
chr1_-_216978709 0.46 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr6_+_53948221 0.46 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr2_+_12246664 0.41 ENST00000449986.1
AC096559.1
AC096559.1
chr9_-_13175823 0.41 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr4_+_108910870 0.41 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chr5_+_140729649 0.40 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr14_+_20443603 0.38 ENST00000305051.5
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr6_+_29424958 0.37 ENST00000377136.1
ENST00000377133.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr3_-_168865522 0.34 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr19_+_47421933 0.33 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr4_-_103998439 0.33 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr6_+_53948328 0.33 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr1_-_247876105 0.32 ENST00000302084.2
OR6F1
olfactory receptor, family 6, subfamily F, member 1
chr22_-_39928823 0.31 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr4_-_103998060 0.28 ENST00000339611.4
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr6_-_138060103 0.28 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1
RP11-356I2.1
chr9_-_95166976 0.28 ENST00000447356.1
OGN
osteoglycin
chrX_-_153141783 0.28 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr2_+_63816295 0.27 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr5_-_119669160 0.26 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr20_-_30310693 0.26 ENST00000307677.4
ENST00000420653.1
BCL2L1
BCL2-like 1
chr20_-_30310656 0.25 ENST00000376055.4
BCL2L1
BCL2-like 1
chr1_+_52082751 0.23 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr4_+_114066764 0.22 ENST00000511380.1
ANK2
ankyrin 2, neuronal
chr15_+_54901540 0.22 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr9_-_93405352 0.21 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr15_-_96036999 0.20 ENST00000554412.2
RP11-398J10.2
RP11-398J10.2
chr7_+_5085452 0.20 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RBAK
RBAK-RBAKDN
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr1_+_229440129 0.19 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr4_+_187813673 0.19 ENST00000606881.1
RP11-11N5.3
RP11-11N5.3
chr3_+_148583043 0.19 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr1_+_192286122 0.18 ENST00000417209.2
RGS21
regulator of G-protein signaling 21
chr20_+_23420885 0.18 ENST00000246020.2
CSTL1
cystatin-like 1
chr1_+_109265033 0.18 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr18_-_68678714 0.15 ENST00000584078.1
RP11-384E22.1
RP11-384E22.1
chr11_-_18956556 0.15 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chr4_-_123542224 0.14 ENST00000264497.3
IL21
interleukin 21
chr12_-_66035968 0.12 ENST00000537250.1
RP11-230G5.2
RP11-230G5.2
chr7_-_45906045 0.12 ENST00000596600.1
AC096582.1
Uncharacterized protein
chr9_-_5833027 0.12 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr6_+_72922505 0.11 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr16_-_8622226 0.11 ENST00000568335.1
TMEM114
transmembrane protein 114
chr17_+_4853442 0.11 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr12_+_96196875 0.10 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr4_+_129349188 0.10 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr10_-_85985282 0.10 ENST00000372113.4
LRIT2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr10_-_85985294 0.09 ENST00000538192.1
LRIT2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr9_-_107361788 0.08 ENST00000374779.2
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr6_+_151358048 0.08 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_14541872 0.08 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr12_-_10978957 0.08 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr10_+_90562487 0.08 ENST00000404743.4
LIPM
lipase, family member M
chr11_+_18154059 0.07 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr3_+_127770455 0.06 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr12_-_66036137 0.06 ENST00000539653.1
ENST00000544557.1
RP11-230G5.2
RP11-230G5.2
chr12_-_99548270 0.05 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_7847519 0.05 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr4_-_987164 0.05 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr5_+_96840389 0.05 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr1_+_192544857 0.04 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr5_+_125758813 0.04 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr9_-_95244781 0.04 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr12_-_49581152 0.03 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr5_+_180794269 0.02 ENST00000456475.1
OR4F3
olfactory receptor, family 4, subfamily F, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 19.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.3 5.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.4 3.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.4 2.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 5.9 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 4.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 1.6 GO:0046968 peptide antigen transport(GO:0046968)
0.3 0.8 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.3 1.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.3 0.8 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.3 0.8 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 1.6 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 1.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 1.1 GO:2000302 regulation of synaptic vesicle priming(GO:0010807) presynaptic dense core granule exocytosis(GO:0099525) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.7 GO:0010157 response to chlorate(GO:0010157)
0.1 7.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 2.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 1.0 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 1.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 2.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.1 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 1.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.8 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 1.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 1.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 1.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.0 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.6 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 1.4 GO:0035556 intracellular signal transduction(GO:0035556)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 19.4 GO:0005577 fibrinogen complex(GO:0005577)
0.9 5.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.1 GO:0044305 calyx of Held(GO:0044305)
0.0 4.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 3.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 5.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 6.3 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0019862 IgA binding(GO:0019862)
1.3 5.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
1.0 3.1 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.9 2.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 2.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.5 4.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.3 0.8 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 7.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 1.6 GO:0046790 virion binding(GO:0046790)
0.1 19.4 GO:0051087 chaperone binding(GO:0051087)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.3 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 1.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 19.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 19.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 5.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells