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Illumina Body Map 2: averaged replicates

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Results for CACAGUG

Z-value: 1.02

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miRNA associated with seed CACAGUG

NamemiRBASE accession
hsa-miR-128-3p
MIMAT0000424
hsa-miR-216a-3p
MIMAT0022844
hsa-miR-3681-3p
MIMAT0018109

Activity profile of CACAGUG motif

Sorted Z-values of CACAGUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_34642656 2.96 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr14_-_30396948 2.53 ENST00000331968.5
PRKD1
protein kinase D1
chrX_+_105066524 2.49 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr6_+_41606176 2.16 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr4_+_55095264 1.95 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_-_205326022 1.90 ENST00000367155.3
KLHDC8A
kelch domain containing 8A
chr7_-_27183263 1.90 ENST00000222726.3
HOXA5
homeobox A5
chr15_+_96873921 1.89 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr16_-_65155833 1.86 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_+_139654018 1.83 ENST00000458420.3
CLSTN2
calsyntenin 2
chr12_-_88974236 1.79 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr17_-_46692287 1.78 ENST00000239144.4
HOXB8
homeobox B8
chr5_-_38595498 1.78 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr1_-_68299130 1.75 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr1_-_57045228 1.73 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr8_+_134203273 1.71 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr14_+_100259666 1.68 ENST00000262233.6
ENST00000334192.4
EML1
echinoderm microtubule associated protein like 1
chr20_+_10199468 1.68 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr19_+_15218180 1.66 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_+_12569306 1.64 ENST00000425538.1
MYOCD
myocardin
chr9_+_132934835 1.63 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr4_+_20255123 1.59 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr5_+_172068232 1.58 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr6_-_166075557 1.55 ENST00000539869.2
ENST00000366882.1
PDE10A
phosphodiesterase 10A
chr17_+_47572647 1.54 ENST00000172229.3
NGFR
nerve growth factor receptor
chr6_+_127439749 1.54 ENST00000356698.4
RSPO3
R-spondin 3
chr12_+_54422142 1.53 ENST00000243108.4
HOXC6
homeobox C6
chr9_+_116917807 1.45 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr2_-_27718052 1.45 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr7_-_27239703 1.44 ENST00000222753.4
HOXA13
homeobox A13
chr1_+_160370344 1.42 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr11_+_12695944 1.41 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_117452669 1.37 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr4_+_85504075 1.35 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr15_+_41221536 1.35 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr18_+_19749386 1.35 ENST00000269216.3
GATA6
GATA binding protein 6
chr15_+_33010175 1.34 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr5_-_121413974 1.33 ENST00000231004.4
LOX
lysyl oxidase
chr8_+_40010989 1.30 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr22_+_41956767 1.27 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr15_-_37390482 1.27 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr15_-_63674218 1.26 ENST00000178638.3
CA12
carbonic anhydrase XII
chr1_+_65613217 1.25 ENST00000545314.1
AK4
adenylate kinase 4
chr14_+_37667118 1.24 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1
mirror-image polydactyly 1
chr8_-_81787006 1.23 ENST00000327835.3
ZNF704
zinc finger protein 704
chr6_+_1312675 1.22 ENST00000296839.2
FOXQ1
forkhead box Q1
chr7_-_103629963 1.22 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr20_+_34700333 1.18 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_-_8534067 1.16 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr1_-_95392635 1.16 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr5_-_57756087 1.14 ENST00000274289.3
PLK2
polo-like kinase 2
chr10_-_131762105 1.14 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr8_+_76452097 1.13 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr17_+_72983674 1.12 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr5_-_179780312 1.11 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr3_-_164913777 1.10 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr1_-_86043921 1.10 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_119399895 1.09 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr4_+_113970772 1.07 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr12_-_77272765 1.07 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr5_-_160279207 1.07 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr1_-_51763661 1.07 ENST00000530004.1
TTC39A
tetratricopeptide repeat domain 39A
chr17_+_11144580 1.06 ENST00000441885.3
ENST00000432116.3
ENST00000409168.3
SHISA6
shisa family member 6
chr2_+_43864387 1.04 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr17_+_8924837 1.03 ENST00000173229.2
NTN1
netrin 1
chr9_-_140196703 1.03 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr18_-_30050395 1.03 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr5_-_115910630 1.03 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_225840747 1.02 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr20_+_2673383 1.02 ENST00000380648.4
ENST00000342725.5
EBF4
early B-cell factor 4
chr8_-_41166953 1.02 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr4_-_177713788 1.00 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr16_+_77822427 0.98 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr4_-_174451370 0.98 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr13_-_107187462 0.98 ENST00000245323.4
EFNB2
ephrin-B2
chr1_-_117210290 0.98 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr5_+_132149017 0.97 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr10_-_90712520 0.96 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr20_-_14318248 0.96 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr16_+_66400533 0.96 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr9_+_124413873 0.93 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr10_-_15762124 0.93 ENST00000378076.3
ITGA8
integrin, alpha 8
chr9_+_118916082 0.92 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_-_14314066 0.90 ENST00000397575.3
NFIB
nuclear factor I/B
chr16_-_70719925 0.89 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr3_+_36421826 0.88 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr4_+_81951957 0.87 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr7_+_94285637 0.87 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr17_-_50237343 0.87 ENST00000575181.1
ENST00000570565.1
CA10
carbonic anhydrase X
chr8_-_97173020 0.86 ENST00000287020.5
GDF6
growth differentiation factor 6
chr12_-_120806960 0.85 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr5_+_34656331 0.85 ENST00000265109.3
RAI14
retinoic acid induced 14
chr4_-_13546632 0.84 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chrX_-_54384425 0.84 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr2_-_166651191 0.83 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr2_-_50574856 0.82 ENST00000342183.5
NRXN1
neurexin 1
chr2_+_189839046 0.82 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr11_-_45687128 0.82 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr4_-_111119804 0.80 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr3_-_56502375 0.80 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr4_+_115519577 0.80 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr6_+_136172820 0.79 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr13_-_103053946 0.78 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr9_+_109625378 0.78 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr7_+_116312411 0.76 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr12_-_105478339 0.75 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr19_+_51815102 0.75 ENST00000270642.8
IGLON5
IgLON family member 5
chr16_+_66878814 0.75 ENST00000394069.3
CA7
carbonic anhydrase VII
chr14_+_101193164 0.74 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr7_-_123673471 0.74 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr5_+_50678921 0.72 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr1_+_110453203 0.72 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr4_-_107957454 0.71 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr14_+_37131058 0.71 ENST00000361487.6
PAX9
paired box 9
chr12_+_79258547 0.68 ENST00000457153.2
SYT1
synaptotagmin I
chr17_+_32907768 0.68 ENST00000321639.5
TMEM132E
transmembrane protein 132E
chr14_-_92413727 0.68 ENST00000267620.10
FBLN5
fibulin 5
chr21_-_39870339 0.66 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr3_-_24536253 0.65 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr5_+_148960931 0.65 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr7_-_27213893 0.65 ENST00000283921.4
HOXA10
homeobox A10
chr8_-_91997427 0.64 ENST00000517562.2
RP11-122A3.2
chromosome 8 open reading frame 88
chr4_+_184826418 0.64 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chrX_+_102631248 0.64 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_+_158114051 0.63 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_+_199996702 0.63 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_+_20522179 0.62 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr15_+_73344791 0.62 ENST00000261908.6
NEO1
neogenin 1
chrX_-_25034065 0.62 ENST00000379044.4
ARX
aristaless related homeobox
chr9_+_103790991 0.61 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr2_-_151344172 0.61 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr3_+_11034403 0.59 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr6_-_88876058 0.58 ENST00000369501.2
CNR1
cannabinoid receptor 1 (brain)
chr1_-_37499726 0.58 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chr7_+_155250824 0.58 ENST00000297375.4
EN2
engrailed homeobox 2
chr17_+_56833184 0.58 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr1_-_154474589 0.58 ENST00000304760.2
SHE
Src homology 2 domain containing E
chr2_+_232260254 0.58 ENST00000287590.5
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr2_+_206547215 0.58 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
NRP2
neuropilin 2
chr17_+_35294075 0.57 ENST00000254457.5
LHX1
LIM homeobox 1
chr8_+_28351707 0.57 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr3_-_170303845 0.55 ENST00000231706.5
SLC7A14
solute carrier family 7, member 14
chr12_-_71031220 0.55 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr5_+_42423872 0.54 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr6_+_118228657 0.54 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr14_-_59932044 0.53 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr4_+_5053162 0.53 ENST00000282908.5
STK32B
serine/threonine kinase 32B
chr20_+_24449821 0.53 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr21_-_43346790 0.52 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr17_-_78450398 0.51 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr1_+_215256467 0.51 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr14_-_27066636 0.51 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr19_-_2721412 0.51 ENST00000323469.4
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr5_+_76506706 0.51 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr3_-_32022733 0.51 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr7_+_100210133 0.51 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr1_-_161059380 0.50 ENST00000368012.3
PVRL4
poliovirus receptor-related 4
chr17_+_1958388 0.50 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr10_+_60272814 0.49 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr2_+_210636697 0.49 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr12_+_103981044 0.49 ENST00000388887.2
STAB2
stabilin 2
chr3_-_116164306 0.48 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr6_-_46293378 0.48 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr1_+_61547894 0.47 ENST00000403491.3
NFIA
nuclear factor I/A
chr20_-_41818373 0.47 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr17_-_41977964 0.47 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr14_+_33408449 0.46 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr2_-_9143786 0.46 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr1_+_205012293 0.46 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr12_-_12419703 0.46 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr10_-_81205373 0.46 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr10_-_21786179 0.45 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr16_+_1756162 0.45 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr12_+_110152033 0.45 ENST00000538780.1
FAM222A
family with sequence similarity 222, member A
chrX_+_17393543 0.45 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_99470558 0.45 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr9_+_116638562 0.44 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr9_-_93405352 0.44 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr14_-_100070363 0.44 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr21_+_35445827 0.43 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr2_-_164592497 0.43 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr12_-_82153087 0.43 ENST00000547623.1
ENST00000549396.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr5_-_93447333 0.43 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr3_-_87040233 0.42 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr2_-_25142708 0.42 ENST00000260600.5
ENST00000435135.1
ADCY3
adenylate cyclase 3
chr6_+_142622991 0.42 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr19_-_14629224 0.42 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr13_-_108518986 0.42 ENST00000375915.2
FAM155A
family with sequence similarity 155, member A
chr6_-_99873145 0.42 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr5_+_52285144 0.41 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr16_-_68482440 0.41 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr21_+_33245548 0.40 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr20_+_20348740 0.40 ENST00000310227.1
INSM1
insulinoma-associated 1
chr1_-_95007193 0.40 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr12_-_109747023 0.39 ENST00000355216.1
ENST00000299162.5
FOXN4
forkhead box N4
chr12_+_70760056 0.39 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr9_-_23821273 0.38 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr6_-_99797522 0.38 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr18_-_31803435 0.38 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4
nucleolar protein 4
chr1_+_116184566 0.38 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CACAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0060435 bronchiole development(GO:0060435)
0.6 2.5 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.6 1.8 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.5 1.6 GO:1902623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5 2.6 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.5 2.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.5 1.4 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.5 1.9 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.3 GO:0007493 endodermal cell fate determination(GO:0007493)
0.4 1.8 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.4 1.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 1.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 1.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.4 1.5 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.3 0.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.3 2.5 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.3 2.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 1.6 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 1.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.7 GO:0060913 cardiac cell fate determination(GO:0060913)
0.2 1.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.4 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.2 0.9 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.0 GO:1901490 positive regulation of mast cell chemotaxis(GO:0060754) regulation of lymphangiogenesis(GO:1901490)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.8 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.7 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.6 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 1.2 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.7 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 2.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.4 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.7 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 2.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 1.0 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.4 GO:0008306 associative learning(GO:0008306)
0.1 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.5 GO:0031133 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.9 GO:2000791 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.9 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.4 GO:0008355 olfactory learning(GO:0008355)
0.1 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0060458 right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516)
0.1 0.6 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1 0.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 1.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.3 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.0 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.1 0.3 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175) galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.1 GO:0001743 optic placode formation(GO:0001743) axial mesoderm formation(GO:0048320)
0.1 0.8 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.8 GO:0007625 grooming behavior(GO:0007625)
0.1 0.2 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.1 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1 1.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.6 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 1.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 1.4 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 1.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 2.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.3 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.5 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.5 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0060187 cell pole(GO:0060187)
0.3 0.9 GO:1990032 parallel fiber(GO:1990032)
0.2 1.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.9 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.2 GO:0097513 myosin II filament(GO:0097513)
0.2 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.6 GO:0042025 host cell nucleus(GO:0042025)
0.1 1.6 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.8 GO:0030175 filopodium(GO:0030175)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 6.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.4 1.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 1.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.3 1.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 0.8 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 1.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.8 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 2.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 2.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.7 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0098821 inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.0 0.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 1.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 11.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 2.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions