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Illumina Body Map 2: averaged replicates

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Results for CCCUGAG

Z-value: 1.34

Motif logo

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miRNA associated with seed CCCUGAG

NamemiRBASE accession
hsa-miR-125a-5p
MIMAT0000443
hsa-miR-125b-5p
MIMAT0000423
hsa-miR-4319
MIMAT0016870

Activity profile of CCCUGAG motif

Sorted Z-values of CCCUGAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_90358048 3.04 ENST00000300060.6
ENST00000560137.1
ANPEP
alanyl (membrane) aminopeptidase
chr6_-_24911195 2.51 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr17_-_61777459 2.44 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr5_-_100238956 2.37 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr15_+_81489213 2.31 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr17_-_76713100 2.27 ENST00000585509.1
CYTH1
cytohesin 1
chr3_-_13461807 2.27 ENST00000254508.5
NUP210
nucleoporin 210kDa
chr3_+_47021168 2.17 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2
neurobeachin-like 2
chr1_+_12227035 2.14 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr3_+_186648274 2.07 ENST00000169298.3
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_+_122526383 2.03 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr6_+_106546808 2.03 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_391739 1.92 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr1_+_26856236 1.91 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_+_10959043 1.82 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr6_-_16761678 1.78 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr15_+_31619013 1.56 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr3_-_183273477 1.54 ENST00000341319.3
KLHL6
kelch-like family member 6
chr2_-_163695128 1.52 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr17_-_38020392 1.49 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr19_-_11450249 1.47 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr19_+_926000 1.43 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr1_-_108507631 1.42 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr11_-_102323489 1.39 ENST00000361236.3
TMEM123
transmembrane protein 123
chr9_-_35650900 1.32 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr9_-_123476719 1.30 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr15_-_61521495 1.30 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr19_-_4066890 1.23 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr11_-_128392085 1.22 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr12_-_58240470 1.21 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_+_127391769 1.20 ENST00000393363.3
ENST00000232744.8
ENST00000453791.2
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr17_-_40540377 1.19 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr10_+_82213904 1.17 ENST00000429989.3
TSPAN14
tetraspanin 14
chr14_-_67982146 1.16 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr3_+_5229356 1.15 ENST00000256497.4
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr15_-_79383102 1.12 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr17_-_66287257 1.11 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr11_-_65381643 1.11 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr18_-_19284724 1.08 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr12_-_54779511 1.07 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr19_-_1863567 1.05 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr3_+_58223228 1.04 ENST00000478253.1
ENST00000295962.4
ABHD6
abhydrolase domain containing 6
chr8_-_63998590 1.02 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr6_-_33547975 1.01 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr10_-_73533255 1.00 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr8_-_8751068 1.00 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr9_+_79074068 1.00 ENST00000444201.2
ENST00000376730.4
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_142985308 0.99 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr5_+_56111361 0.99 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr3_-_72496035 0.98 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr5_-_175964366 0.96 ENST00000274811.4
RNF44
ring finger protein 44
chr19_+_13261216 0.95 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr16_-_85045131 0.95 ENST00000313732.4
ZDHHC7
zinc finger, DHHC-type containing 7
chr12_+_83080659 0.94 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr12_-_110318263 0.94 ENST00000318348.4
GLTP
glycolipid transfer protein
chr1_-_200379180 0.94 ENST00000294740.3
ZNF281
zinc finger protein 281
chr14_+_70078303 0.94 ENST00000342745.4
KIAA0247
KIAA0247
chr1_-_111682662 0.94 ENST00000286692.4
DRAM2
DNA-damage regulated autophagy modulator 2
chr8_-_141645645 0.94 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr5_+_156887027 0.92 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr8_-_53322303 0.92 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr13_-_53024725 0.91 ENST00000378060.4
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr6_-_32811771 0.91 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr19_-_19754404 0.91 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr1_+_47901689 0.90 ENST00000334793.5
FOXD2
forkhead box D2
chr12_+_111843749 0.90 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr8_-_66754172 0.90 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr12_+_104359576 0.89 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr20_-_62610982 0.89 ENST00000369886.3
ENST00000450107.1
SAMD10
sterile alpha motif domain containing 10
chr2_+_5832799 0.88 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr12_+_122150646 0.87 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr18_-_43652211 0.85 ENST00000589328.1
ENST00000409746.5
PSTPIP2
proline-serine-threonine phosphatase interacting protein 2
chr1_+_89990431 0.85 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr6_-_90062543 0.85 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr12_-_56224546 0.85 ENST00000357606.3
ENST00000547445.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr3_-_52090461 0.84 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr2_-_201936302 0.84 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr12_+_11802753 0.83 ENST00000396373.4
ETV6
ets variant 6
chr17_-_27507395 0.81 ENST00000354329.4
ENST00000527372.1
MYO18A
myosin XVIIIA
chr3_+_141205852 0.81 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr5_+_74632993 0.79 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr11_+_58939965 0.78 ENST00000227451.3
DTX4
deltex homolog 4 (Drosophila)
chr1_-_23857698 0.78 ENST00000361729.2
E2F2
E2F transcription factor 2
chr15_+_63481668 0.77 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr12_+_53774423 0.76 ENST00000426431.2
SP1
Sp1 transcription factor
chr6_-_30658745 0.76 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chrX_+_153639856 0.76 ENST00000426834.1
ENST00000369790.4
ENST00000454722.1
ENST00000350743.4
ENST00000299328.5
ENST00000351413.4
TAZ
tafazzin
chr11_-_78052923 0.76 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr8_+_37887772 0.76 ENST00000338825.4
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr15_-_23086394 0.74 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr1_-_21671968 0.74 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr12_+_56521840 0.73 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr12_-_68553512 0.73 ENST00000229135.3
IFNG
interferon, gamma
chr3_-_48672859 0.73 ENST00000395550.2
ENST00000455886.2
ENST00000431739.1
ENST00000426599.1
ENST00000383733.3
ENST00000420764.2
ENST00000337000.8
SLC26A6
solute carrier family 26 (anion exchanger), member 6
chr9_+_33817461 0.73 ENST00000263228.3
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr11_+_94277017 0.73 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr12_+_49932886 0.70 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_+_75526212 0.70 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr9_-_130829588 0.70 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chrX_+_78003204 0.70 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr2_+_131113580 0.70 ENST00000175756.5
PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr12_-_69326940 0.70 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr10_+_72575643 0.69 ENST00000373202.3
SGPL1
sphingosine-1-phosphate lyase 1
chr5_+_96271141 0.69 ENST00000231368.5
LNPEP
leucyl/cystinyl aminopeptidase
chrX_-_103401649 0.68 ENST00000357421.4
SLC25A53
solute carrier family 25, member 53
chr17_-_40761375 0.68 ENST00000543197.1
ENST00000309428.5
FAM134C
family with sequence similarity 134, member C
chr7_-_139876812 0.67 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr17_+_73512594 0.67 ENST00000333213.6
TSEN54
TSEN54 tRNA splicing endonuclease subunit
chr11_-_64901978 0.67 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr10_-_118764862 0.66 ENST00000260777.10
KIAA1598
KIAA1598
chr3_+_15468862 0.66 ENST00000396842.2
EAF1
ELL associated factor 1
chr1_-_207224307 0.66 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr2_-_85555385 0.65 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr5_+_80256453 0.65 ENST00000265080.4
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr14_-_73493825 0.64 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr16_-_23521710 0.64 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr2_+_12857015 0.64 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr17_-_48227877 0.64 ENST00000316878.6
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr12_+_50135588 0.64 ENST00000423828.1
ENST00000550445.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr1_+_36273743 0.64 ENST00000373210.3
AGO4
argonaute RISC catalytic component 4
chr9_+_129622904 0.64 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr7_-_143059845 0.63 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr1_+_203274639 0.63 ENST00000290551.4
BTG2
BTG family, member 2
chr12_-_51717922 0.63 ENST00000452142.2
BIN2
bridging integrator 2
chr10_-_60027642 0.63 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr17_+_61699766 0.62 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr17_+_53828381 0.62 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr12_+_68042495 0.62 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr17_-_27224621 0.62 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
FLOT2
flotillin 2
chr11_-_65769594 0.62 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chr8_-_95961578 0.62 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr2_+_47168313 0.60 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr17_-_79876010 0.60 ENST00000328666.6
SIRT7
sirtuin 7
chr22_-_37608325 0.60 ENST00000328544.3
SSTR3
somatostatin receptor 3
chr1_+_160051319 0.60 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr5_-_134788086 0.59 ENST00000537858.1
TIFAB
TRAF-interacting protein with forkhead-associated domain, family member B
chr6_-_43596899 0.58 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr5_+_110559784 0.58 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr18_+_19321281 0.58 ENST00000261537.6
MIB1
mindbomb E3 ubiquitin protein ligase 1
chr4_-_57301748 0.57 ENST00000264220.2
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr5_-_131347306 0.57 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6
acyl-CoA synthetase long-chain family member 6
chr5_+_177019159 0.57 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr1_+_178694300 0.56 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr10_-_14590644 0.56 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr19_+_13906250 0.54 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr5_+_151151471 0.54 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr16_-_2264779 0.53 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr18_+_32558208 0.53 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr2_-_158485387 0.53 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr11_+_45825896 0.53 ENST00000314134.3
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr12_+_65004292 0.53 ENST00000542104.1
ENST00000336061.2
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chr6_-_31830655 0.53 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chr5_-_133561752 0.53 ENST00000519718.1
ENST00000481195.1
CTD-2410N18.5
PPP2CA
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr7_-_106301405 0.52 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr1_+_32573636 0.52 ENST00000373625.3
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr10_-_94003003 0.52 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr16_-_71610985 0.51 ENST00000355962.4
TAT
tyrosine aminotransferase
chr1_+_26737253 0.51 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr2_+_61293021 0.51 ENST00000402291.1
KIAA1841
KIAA1841
chr5_+_133861790 0.50 ENST00000395003.1
PHF15
jade family PHD finger 2
chr8_-_67579418 0.50 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr13_-_29292956 0.50 ENST00000266943.6
SLC46A3
solute carrier family 46, member 3
chr1_-_179198702 0.50 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr2_+_7057523 0.50 ENST00000320892.6
RNF144A
ring finger protein 144A
chr22_-_37099555 0.50 ENST00000300105.6
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr17_+_2496971 0.50 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_-_39195037 0.49 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_+_19303008 0.49 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr11_-_67169253 0.49 ENST00000527663.1
ENST00000312989.7
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr13_+_41363581 0.49 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr8_-_23315190 0.48 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr6_+_18387570 0.48 ENST00000259939.3
RNF144B
ring finger protein 144B
chr14_-_91976488 0.48 ENST00000554684.1
ENST00000337238.4
ENST00000428424.2
ENST00000554511.1
SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr20_-_31071239 0.48 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr18_-_60987220 0.47 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr12_+_50690489 0.47 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr10_+_72432559 0.46 ENST00000373208.1
ENST00000373207.1
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr3_-_53381539 0.46 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A
decapping mRNA 1A
chr14_+_71374122 0.46 ENST00000304743.2
ENST00000238570.5
PCNX
pecanex homolog (Drosophila)
chr1_+_165796753 0.46 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr6_+_35995488 0.46 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chr10_+_65281123 0.45 ENST00000298249.4
ENST00000373758.4
REEP3
receptor accessory protein 3
chr12_-_117319236 0.45 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_23495340 0.45 ENST00000418342.1
LUZP1
leucine zipper protein 1
chr2_-_97535708 0.45 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr9_-_19786926 0.45 ENST00000341998.2
ENST00000286344.3
SLC24A2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr1_-_36022979 0.45 ENST00000469892.1
ENST00000325722.3
KIAA0319L
KIAA0319-like
chr17_+_38375574 0.45 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr4_+_174089904 0.45 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr11_-_36531774 0.45 ENST00000348124.5
ENST00000526995.1
TRAF6
TNF receptor-associated factor 6, E3 ubiquitin protein ligase
chr2_-_206950781 0.44 ENST00000403263.1
INO80D
INO80 complex subunit D
chr5_+_137673945 0.44 ENST00000513056.1
ENST00000511276.1
FAM53C
family with sequence similarity 53, member C
chr1_-_173174681 0.44 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr20_+_62795827 0.44 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr9_-_130497565 0.43 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
TOR2A
torsin family 2, member A
chr11_+_61447845 0.43 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr8_+_22857048 0.43 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr4_+_25235597 0.43 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr8_-_74791051 0.42 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr14_+_60715928 0.42 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A

Network of associatons between targets according to the STRING database.

First level regulatory network of CCCUGAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.6 1.9 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.0 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 1.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 0.9 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.6 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.7 GO:2000309 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.2 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 1.6 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 0.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 0.6 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.2 0.6 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.2 1.0 GO:0090212 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.2 0.8 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.6 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.2 1.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 1.5 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.2 0.9 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.5 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 0.5 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.2 0.5 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 0.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.2 0.6 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 0.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 1.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.2 GO:0030578 PML body organization(GO:0030578)
0.2 0.6 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.2 0.5 GO:0021503 neural fold bending(GO:0021503)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.2 GO:0046836 glycolipid transport(GO:0046836)
0.1 2.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.4 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.4 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.7 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.6 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.4 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.5 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 2.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.8 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 2.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 0.5 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 1.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.4 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 2.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.6 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.0 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.4 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 1.6 GO:0002467 germinal center formation(GO:0002467)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.1 0.9 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.6 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 0.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 2.4 GO:0030220 platelet formation(GO:0030220)
0.1 0.9 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.3 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.5 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.1 GO:0021699 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.1 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.3 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.7 GO:0001553 luteinization(GO:0001553)
0.0 1.5 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 2.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 2.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.6 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.4 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.3 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:1905071 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.5 GO:0061157 mRNA destabilization(GO:0061157)
0.0 2.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0051292 nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0072719 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 1.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:0071800 podosome assembly(GO:0071800)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)
0.0 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0000814 ESCRT II complex(GO:0000814)
0.3 2.6 GO:0043196 varicosity(GO:0043196)
0.3 1.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.5 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.7 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0097196 Shu complex(GO:0097196)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.8 GO:0051286 cell tip(GO:0051286)
0.1 1.5 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 1.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 3.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.3 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 3.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.2 0.9 GO:0098808 mRNA cap binding(GO:0098808)
0.2 1.6 GO:0034046 poly(G) binding(GO:0034046)
0.2 1.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 2.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 2.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.5 GO:0038100 nodal binding(GO:0038100)
0.2 0.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.7 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.3 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.5 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 1.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 4.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.2 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.5 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.6 GO:0051400 BH domain binding(GO:0051400)
0.1 0.7 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.5 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 2.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 1.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 2.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 1.8 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 2.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252) 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID EPO PATHWAY EPO signaling pathway
0.0 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 4.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 6.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis