Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for CDC5L
Z-value: 2.54
Motif logo
Transcription factors associated with CDC5L
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CDC5L | hg19_v2_chr6_+_44355257_44355315 | 0.29 | 1.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_616711 Show fit | 8.34 |
ENST00000579494.1
|
clusterin-like 1 (retinal) |
|
| chr18_+_616672 Show fit | 7.97 |
ENST00000338387.7
|
clusterin-like 1 (retinal) |
|
| chr10_-_69597915 Show fit | 6.20 |
ENST00000225171.2
|
DnaJ (Hsp40) homolog, subfamily C, member 12 |
|
| chr3_+_178276488 Show fit | 5.81 |
ENST00000432997.1
ENST00000455865.1 |
potassium large conductance calcium-activated channel, subfamily M, beta member 2 |
|
| chr10_-_69597810 Show fit | 5.79 |
ENST00000483798.2
|
DnaJ (Hsp40) homolog, subfamily C, member 12 |
|
| chr7_-_16921601 Show fit | 5.11 |
ENST00000402239.3
ENST00000310398.2 ENST00000414935.1 |
anterior gradient 3 |
|
| chr8_-_124749609 Show fit | 5.06 |
ENST00000262219.6
ENST00000419625.1 |
annexin A13 |
|
| chr9_-_28670283 Show fit | 4.79 |
ENST00000379992.2
|
leucine rich repeat and Ig domain containing 2 |
|
| chr10_-_69597828 Show fit | 4.13 |
ENST00000339758.7
|
DnaJ (Hsp40) homolog, subfamily C, member 12 |
|
| chr16_+_80574854 Show fit | 3.67 |
ENST00000305904.6
ENST00000568035.1 |
dynein, light chain, roadblock-type 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CDC5L
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.1 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.3 | 5.8 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.5 | 4.8 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 4.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 4.5 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 4.4 | GO:0046710 | GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120) |
| 0.1 | 4.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 3.8 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 3.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.6 | 3.6 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 9.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.2 | 5.7 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.5 | 4.8 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.4 | 4.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 4.5 | GO:0030286 | dynein complex(GO:0030286) |
| 0.1 | 3.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 3.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.4 | 3.6 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 3.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 5.8 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.5 | 5.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.7 | 5.1 | GO:0050429 | calcium-dependent phospholipase C activity(GO:0050429) |
| 0.1 | 4.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.2 | 4.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 3.8 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 3.8 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 3.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 3.5 | GO:0045294 | alpha-catenin binding(GO:0045294) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 5.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.2 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 4.5 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 2.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 2.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 2.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.4 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 6.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 4.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 3.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 3.3 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 3.0 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.2 | 2.8 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 2.5 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 2.5 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |