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Illumina Body Map 2: averaged replicates

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Results for CDX1

Z-value: 1.33

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Transcription factors associated with CDX1

Gene Symbol Gene ID Gene Info
ENSG00000113722.12 caudal type homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX1hg19_v2_chr5_+_149546334_149546364-0.105.8e-01Click!

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_88427568 5.41 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr5_-_147211226 4.13 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr20_+_56136136 2.75 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr5_-_41261540 2.48 ENST00000263413.3
complement component 6
chr1_+_159557607 2.02 ENST00000255040.2
amyloid P component, serum
chr2_-_151344172 2.00 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr7_-_16840820 1.98 ENST00000450569.1
anterior gradient 2
chr11_+_114168085 1.95 ENST00000541754.1
nicotinamide N-methyltransferase
chr11_+_112046190 1.89 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
beta-carotene oxygenase 2
chr16_+_56672571 1.84 ENST00000290705.8
metallothionein 1A
chr12_-_9268707 1.83 ENST00000318602.7
alpha-2-macroglobulin
chr8_+_76452097 1.81 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr4_-_186578674 1.72 ENST00000438278.1
sorbin and SH3 domain containing 2
chr9_-_95244781 1.69 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr12_-_9268819 1.68 ENST00000404455.2
alpha-2-macroglobulin
chr4_-_110723194 1.64 ENST00000394635.3
complement factor I
chr1_+_196743912 1.62 ENST00000367425.4
complement factor H-related 3
chr3_-_196242233 1.62 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr10_-_69597915 1.58 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_108672742 1.58 ENST00000261047.3
guanylate cyclase activator 1C
chr10_-_52645416 1.52 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr4_-_110723335 1.50 ENST00000394634.2
complement factor I
chr5_+_75904918 1.49 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQ motif containing GTPase activating protein 2
chr18_-_68004529 1.48 ENST00000578633.1
RP11-484N16.1
chr4_+_74269956 1.46 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr5_+_75904950 1.43 ENST00000502745.1
IQ motif containing GTPase activating protein 2
chr11_+_112041253 1.40 ENST00000532612.1
AP002884.3
chr5_-_147211190 1.39 ENST00000510027.2
serine peptidase inhibitor, Kazal type 1
chr7_+_80275953 1.37 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr4_-_186732048 1.35 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr4_-_16085340 1.35 ENST00000508167.1
prominin 1
chr19_+_46367518 1.34 ENST00000302177.2
forkhead box A3
chr4_-_110723134 1.33 ENST00000510800.1
ENST00000512148.1
complement factor I
chr10_-_95360983 1.32 ENST00000371464.3
retinol binding protein 4, plasma
chr8_-_123706338 1.30 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr4_-_16085314 1.30 ENST00000510224.1
prominin 1
chrX_+_114874727 1.29 ENST00000543070.1
plastin 3
chr17_-_53809473 1.28 ENST00000575734.1
transmembrane protein 100
chr1_+_57320437 1.26 ENST00000361249.3
complement component 8, alpha polypeptide
chr10_-_69597810 1.26 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr20_-_7238861 1.26 ENST00000428954.1
RP11-19D2.1
chr3_+_149192475 1.25 ENST00000465758.1
transmembrane 4 L six family member 4
chr8_+_67039278 1.24 ENST00000276573.7
ENST00000350034.4
tripartite motif containing 55
chrX_+_99899180 1.23 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr4_-_186732241 1.23 ENST00000421639.1
sorbin and SH3 domain containing 2
chr16_+_82068585 1.23 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_175443943 1.22 ENST00000296522.6
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_196743943 1.21 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr3_-_168865522 1.17 ENST00000464456.1
MDS1 and EVI1 complex locus
chr12_-_91573249 1.15 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr2_-_89161432 1.15 ENST00000390242.2
immunoglobulin kappa joining 1
chrX_-_15619076 1.14 ENST00000252519.3
angiotensin I converting enzyme 2
chr3_-_108672609 1.14 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr10_-_69597828 1.13 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr4_-_71532339 1.12 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_-_92855762 1.12 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr4_-_152149033 1.11 ENST00000514152.1
SH3 domain containing 19
chr14_+_100789669 1.11 ENST00000361529.3
ENST00000557052.1
solute carrier family 25, member 47
chr4_-_71532207 1.11 ENST00000543780.1
ENST00000391614.3
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_+_69857515 1.08 ENST00000559477.1
RP11-279F6.1
chr2_-_89521942 1.07 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr4_-_100065419 1.06 ENST00000504125.1
ENST00000505590.1
alcohol dehydrogenase 4 (class II), pi polypeptide
chr11_-_2158507 1.05 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
insulin-like growth factor 2 (somatomedin A)
chr1_+_171283331 1.04 ENST00000367749.3
flavin containing monooxygenase 4
chr14_-_67878917 1.04 ENST00000216446.4
pleckstrin 2
chr1_+_81771806 1.03 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr6_-_55740352 1.01 ENST00000370830.3
bone morphogenetic protein 5
chr4_-_186733119 1.00 ENST00000419063.1
sorbin and SH3 domain containing 2
chr16_+_56685796 1.00 ENST00000334346.2
ENST00000562399.1
metallothionein 1B
chr17_-_56492989 0.99 ENST00000583753.1
ring finger protein 43
chr2_-_165424973 0.99 ENST00000543549.1
growth factor receptor-bound protein 14
chr2_-_238305397 0.99 ENST00000409809.1
collagen, type VI, alpha 3
chr10_+_85933494 0.99 ENST00000372126.3
chromosome 10 open reading frame 99
chr21_-_43735628 0.95 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr12_+_16500037 0.95 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr2_-_163008903 0.93 ENST00000418842.2
ENST00000375497.3
glucagon
chrX_+_110754888 0.93 ENST00000569275.1
ENST00000563467.1
long intergenic non-protein coding RNA 890
chr3_-_149095652 0.92 ENST00000305366.3
transmembrane 4 L six family member 1
chr21_-_43735446 0.91 ENST00000398431.2
trefoil factor 3 (intestinal)
chrX_-_15333775 0.91 ENST00000480796.1
ankyrin repeat and SOCS box containing 11
chr10_-_52645379 0.91 ENST00000395489.2
APOBEC1 complementation factor
chr11_+_112047087 0.89 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr12_-_91573132 0.89 ENST00000550563.1
ENST00000546370.1
decorin
chr15_+_71839566 0.89 ENST00000357769.4
thrombospondin, type I, domain containing 4
chr12_+_59989918 0.88 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_+_80267949 0.87 ENST00000482059.2
CD36 molecule (thrombospondin receptor)
chr1_+_212475148 0.86 ENST00000537030.3
protein phosphatase 2, regulatory subunit B', alpha
chr4_+_71063641 0.84 ENST00000514097.1
odontogenic, ameloblast asssociated
chr6_-_138866823 0.84 ENST00000342260.5
NHS-like 1
chr3_-_148939598 0.80 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr2_+_34935472 0.80 ENST00000604250.1
AC073218.2
chr3_+_135741576 0.80 ENST00000334546.2
protein phosphatase 2, regulatory subunit B'', alpha
chr4_-_100065440 0.78 ENST00000508393.1
ENST00000265512.7
alcohol dehydrogenase 4 (class II), pi polypeptide
chr11_+_114310164 0.77 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr12_+_20963632 0.77 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr7_+_80267973 0.77 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr4_-_175205407 0.77 ENST00000393674.2
F-box protein 8
chr11_-_89224508 0.77 ENST00000525196.1
NADPH oxidase 4
chr12_+_20963647 0.76 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr22_+_21128167 0.75 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_-_22444733 0.75 ENST00000508133.1
G protein-coupled receptor 125
chr3_+_119501557 0.74 ENST00000337940.4
nuclear receptor subfamily 1, group I, member 2
chr3_+_186285192 0.74 ENST00000439351.1
DnaJ (Hsp40) homolog, subfamily B, member 11
chr1_-_935491 0.73 ENST00000304952.6
hes family bHLH transcription factor 4
chr3_+_190333097 0.73 ENST00000412080.1
interleukin 1 receptor accessory protein
chr1_-_68299130 0.73 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr11_-_2182388 0.71 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr5_-_95550754 0.71 ENST00000502437.1
RP11-254I22.3
chr7_+_120629653 0.71 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr11_+_107992243 0.70 ENST00000265838.4
ENST00000299355.6
acetyl-CoA acetyltransferase 1
chr15_-_45670924 0.68 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_42358742 0.68 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr4_+_159727272 0.68 ENST00000379346.3
folliculin interacting protein 2
chr13_-_41111323 0.68 ENST00000595486.1
Uncharacterized protein
chr13_-_33780133 0.68 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr6_+_161123270 0.68 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr12_-_371994 0.67 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr1_+_223101757 0.66 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr12_+_19389814 0.66 ENST00000536974.1
pleckstrin homology domain containing, family A member 5
chr4_+_159727222 0.65 ENST00000512986.1
folliculin interacting protein 2
chr14_-_53331239 0.65 ENST00000553663.1
fermitin family member 2
chr11_-_8795787 0.65 ENST00000528196.1
ENST00000533681.1
suppression of tumorigenicity 5
chr9_-_95186739 0.65 ENST00000375550.4
osteomodulin
chr4_-_100065389 0.65 ENST00000512499.1
alcohol dehydrogenase 4 (class II), pi polypeptide
chr17_+_41005283 0.65 ENST00000592999.1
amine oxidase, copper containing 3
chr18_+_3449695 0.64 ENST00000343820.5
TGFB-induced factor homeobox 1
chr4_+_117220016 0.64 ENST00000604093.1
MT-RNR2-like 13 (pseudogene)
chr2_+_89901292 0.64 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr3_-_96337000 0.63 ENST00000600213.2
MT-RNR2-like 12 (pseudogene)
chr17_-_67057114 0.63 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr18_-_712544 0.62 ENST00000340116.7
ENST00000539164.1
ENST00000580982.1
enolase superfamily member 1
chr20_+_30795664 0.62 ENST00000375749.3
ENST00000375730.3
ENST00000539210.1
protein O-fucosyltransferase 1
chr11_+_28129795 0.62 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr18_-_712618 0.62 ENST00000583771.1
ENST00000383578.3
ENST00000251101.7
enolase superfamily member 1
chr3_-_100712352 0.62 ENST00000471714.1
ENST00000284322.5
ABI family, member 3 (NESH) binding protein
chr22_+_25595817 0.61 ENST00000215855.2
ENST00000404334.1
crystallin, beta B3
chr1_+_175036966 0.61 ENST00000239462.4
tenascin N
chr1_+_196857144 0.60 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr4_+_70146217 0.59 ENST00000335568.5
ENST00000511240.1
UDP glucuronosyltransferase 2 family, polypeptide B28
chr1_+_63073437 0.59 ENST00000593719.1
CDNA FLJ26506 fis, clone KDN07105; Uncharacterized protein
chr2_+_33359687 0.58 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr3_+_158787041 0.58 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr18_-_57027194 0.57 ENST00000251047.5
lectin, mannose-binding, 1
chr2_-_190448118 0.57 ENST00000440626.1
solute carrier family 40 (iron-regulated transporter), member 1
chr14_-_23623577 0.56 ENST00000422941.2
ENST00000453702.1
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr4_+_169418195 0.55 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr6_+_125304502 0.55 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
ring finger protein 217
chr4_-_47983519 0.55 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr4_+_169418255 0.55 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr16_+_56691606 0.54 ENST00000334350.6
metallothionein 1F
chr16_+_2014941 0.54 ENST00000531523.1
small nucleolar RNA host gene 9 (non-protein coding)
chr11_-_89224667 0.54 ENST00000393282.2
NADPH oxidase 4
chr6_-_112575912 0.54 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr12_-_9760482 0.54 ENST00000229402.3
killer cell lectin-like receptor subfamily B, member 1
chr4_-_83765613 0.53 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr5_+_138210919 0.53 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr2_+_33359646 0.53 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chrX_-_45629661 0.53 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr12_+_19358228 0.52 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr4_-_71532668 0.52 ENST00000510437.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_+_26087646 0.52 ENST00000309234.6
hemochromatosis
chrX_-_131547625 0.51 ENST00000394311.2
muscleblind-like splicing regulator 3
chr10_+_114169299 0.51 ENST00000369410.3
acyl-CoA synthetase long-chain family member 5
chr15_-_67351586 0.51 ENST00000558071.1
RP11-798K3.2
chr15_-_83474806 0.51 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr12_-_111358372 0.51 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chrX_-_131547596 0.51 ENST00000538204.1
ENST00000370849.3
muscleblind-like splicing regulator 3
chr1_+_89246647 0.51 ENST00000544045.1
protein kinase N2
chr15_+_55700741 0.51 ENST00000569691.1
chromosome 15 open reading frame 65
chr3_-_100712292 0.50 ENST00000495063.1
ENST00000530539.1
ABI family, member 3 (NESH) binding protein
chrX_-_131623982 0.50 ENST00000370844.1
muscleblind-like splicing regulator 3
chr17_+_22022437 0.50 ENST00000540040.1
MT-RNR2-like 1
chr1_+_169079823 0.49 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_-_48943706 0.49 ENST00000499247.2
transducer of ERBB2, 1
chr4_-_137842536 0.49 ENST00000512039.1
RP11-138I17.1
chr13_-_114107839 0.49 ENST00000375418.3
ADP-ribosylhydrolase like 1
chr5_+_96079240 0.49 ENST00000515663.1
calpastatin
chr16_-_1275257 0.49 ENST00000234798.4
tryptase gamma 1
chr2_-_89619904 0.47 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr13_+_49684445 0.47 ENST00000398316.3
fibronectin type III domain containing 3A
chr8_-_16035454 0.47 ENST00000355282.2
macrophage scavenger receptor 1
chr14_+_37641012 0.47 ENST00000556667.1
SLC25A21 antisense RNA 1
chrX_-_99987088 0.47 ENST00000372981.1
ENST00000263033.5
synaptotagmin-like 4
chr2_-_40657397 0.47 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_24489842 0.46 ENST00000230036.1
glycosylphosphatidylinositol specific phospholipase D1
chrM_+_14741 0.46 ENST00000361789.2
mitochondrially encoded cytochrome b
chr11_-_89224638 0.46 ENST00000535633.1
ENST00000263317.4
NADPH oxidase 4
chr1_-_156265438 0.46 ENST00000362007.1
chromosome 1 open reading frame 85
chr10_-_22292613 0.46 ENST00000376980.3
DnaJ (Hsp40) homolog, subfamily C, member 1
chr9_+_108463234 0.46 ENST00000374688.1
transmembrane protein 38B
chr18_+_55712915 0.45 ENST00000592846.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr7_+_23210760 0.45 ENST00000366347.4
Uncharacterized protein
chr5_-_79946820 0.45 ENST00000604882.1
MT-RNR2-like 2
chrX_-_109590174 0.44 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr12_-_15815626 0.44 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr6_+_26087509 0.44 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr4_-_185729602 0.44 ENST00000437665.3
acyl-CoA synthetase long-chain family member 1
chr17_-_46690839 0.43 ENST00000498634.2
homeobox B8
chr9_+_124103625 0.43 ENST00000594963.1
Uncharacterized protein
chr12_+_80730292 0.43 ENST00000298820.3
otogelin-like

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.9 2.8 GO:0042214 terpene metabolic process(GO:0042214)
0.9 5.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.7 2.8 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.5 2.6 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.5 2.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.5 1.5 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.4 0.7 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3 1.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 1.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.3 1.0 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 5.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 0.9 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.3 2.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3 2.0 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3 1.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 0.8 GO:0061508 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.3 3.0 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.7 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.2 1.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.2 0.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 0.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.2 0.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 2.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.2 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2 0.9 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.2 2.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 0.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 4.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 1.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 2.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.5 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.8 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.9 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 2.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 1.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 3.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 4.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:1902304 phosphatidylserine exposure on blood platelet(GO:0097045) positive regulation of potassium ion export(GO:1902304)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.6 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.4 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 9.3 GO:0030449 regulation of complement activation(GO:0030449)
0.1 1.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.2 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.1 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.3 GO:1902527 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:0035799 ureter maturation(GO:0035799)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.7 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.7 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.4 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.9 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 1.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775) vitamin A metabolic process(GO:0006776)
0.0 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.5 GO:0035640 exploration behavior(GO:0035640)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.5 GO:0055001 muscle cell development(GO:0055001)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0001696 gastric acid secretion(GO:0001696)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.4 3.7 GO:0005579 membrane attack complex(GO:0005579)
0.3 5.4 GO:0045179 apical cortex(GO:0045179)
0.2 3.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 3.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.0 GO:1990357 terminal web(GO:1990357)
0.1 3.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 2.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 3.5 GO:0031941 filamentous actin(GO:0031941)
0.0 11.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 5.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 6.4 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 1.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.8 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 2.5 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.8 5.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 3.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.5 2.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.4 2.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.4 1.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.3 1.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 3.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.5 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:1904854 proteasome core complex binding(GO:1904854)
0.2 0.9 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 3.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 0.6 GO:0097689 iron channel activity(GO:0097689)
0.2 1.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 1.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 5.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.5 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 2.3 GO:0016918 retinal binding(GO:0016918)
0.1 0.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.3 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.8 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.0 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 4.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.3 GO:0001848 complement binding(GO:0001848)
0.0 0.9 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 6.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 4.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 2.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 3.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 5.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 5.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 2.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 8.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 3.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 3.0 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation