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Illumina Body Map 2: averaged replicates

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Results for CDX2

Z-value: 1.14

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
ENSG00000165556.9 caudal type homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg19_v2_chr13_-_28545276_28545276-0.291.1e-01Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_105937068 1.67 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_237167718 1.66 ENST00000464121.2
metallothionein 1H-like 1
chrX_+_105936982 1.60 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr22_+_32455111 1.59 ENST00000543737.1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_+_39944025 1.33 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr12_-_112443767 1.26 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
transmembrane protein 116
chr10_-_94301107 1.26 ENST00000436178.1
insulin-degrading enzyme
chr12_-_112443830 1.26 ENST00000550037.1
ENST00000549425.1
transmembrane protein 116
chrM_+_10464 1.17 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr10_-_103599591 1.14 ENST00000348850.5
Kv channel interacting protein 2
chr17_+_58018269 1.11 ENST00000591035.1
Uncharacterized protein
chr6_+_111408698 1.07 ENST00000368851.5
solute carrier family 16 (aromatic amino acid transporter), member 10
chr1_+_74701062 0.90 ENST00000326637.3
TNNI3 interacting kinase
chr5_+_36608280 0.90 ENST00000513646.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_72649763 0.89 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr10_-_24770632 0.88 ENST00000596413.1
AL353583.1
chr22_+_17956618 0.88 ENST00000262608.8
cat eye syndrome chromosome region, candidate 2
chr7_+_138915102 0.88 ENST00000486663.1
ubinuclein 2
chrX_-_15619076 0.88 ENST00000252519.3
angiotensin I converting enzyme 2
chr9_-_98189055 0.87 ENST00000433644.2
RP11-435O5.2
chr11_+_112047087 0.87 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr6_+_53948328 0.85 ENST00000370876.2
muscular LMNA-interacting protein
chr5_+_36606700 0.83 ENST00000416645.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_155484155 0.82 ENST00000509493.1
fibrinogen beta chain
chr2_-_40657397 0.81 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_-_108672742 0.79 ENST00000261047.3
guanylate cyclase activator 1C
chr6_+_78400375 0.79 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr4_-_140222358 0.78 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_3663212 0.78 ENST00000397067.3
ADP-ribosyltransferase 5
chr3_-_108672609 0.78 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr4_+_155484103 0.77 ENST00000302068.4
fibrinogen beta chain
chr3_-_18480173 0.75 ENST00000414509.1
SATB homeobox 1
chr9_-_28670283 0.75 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr6_+_12958137 0.70 ENST00000457702.2
ENST00000379345.2
phosphatase and actin regulator 1
chr1_+_154401791 0.69 ENST00000476006.1
interleukin 6 receptor
chr17_+_45286706 0.69 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr7_+_35756092 0.69 ENST00000458087.3
AC018647.3
chr20_-_36152914 0.68 ENST00000397131.1
bladder cancer associated protein
chr3_-_18480260 0.66 ENST00000454909.2
SATB homeobox 1
chrM_+_10053 0.63 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr6_+_47666275 0.62 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr1_+_52682052 0.62 ENST00000371591.1
zinc finger, FYVE domain containing 9
chr2_-_122262593 0.62 ENST00000418989.1
cytoplasmic linker associated protein 1
chr4_+_146539415 0.59 ENST00000281317.5
methylmalonic aciduria (cobalamin deficiency) cblA type
chr10_-_115614127 0.58 ENST00000369305.1
DNA cross-link repair 1A
chrX_-_30993201 0.58 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_+_115614370 0.58 ENST00000369301.3
NHL repeat containing 2
chr6_+_143447322 0.55 ENST00000458219.1
androgen-induced 1
chr3_+_125687987 0.53 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
rhophilin associated tail protein 1B
chr6_+_25754927 0.53 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr22_+_41956767 0.53 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr7_+_80275663 0.53 ENST00000413265.1
CD36 molecule (thrombospondin receptor)
chr20_-_7921090 0.51 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_42984330 0.50 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr7_+_35756186 0.50 ENST00000430518.1
AC018647.3
chr10_-_129691195 0.50 ENST00000368671.3
clarin 3
chr16_-_66907139 0.50 ENST00000561579.2
NEDD8 activating enzyme E1 subunit 1
chr2_-_51259292 0.50 ENST00000401669.2
neurexin 1
chr4_-_169239921 0.50 ENST00000514995.1
ENST00000393743.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr18_-_52989217 0.50 ENST00000570287.2
transcription factor 4
chr13_-_50020554 0.49 ENST00000400396.1
Sarcoma antigen NY-SAR-79; Uncharacterized protein
chr2_-_51259229 0.49 ENST00000405472.3
neurexin 1
chr3_-_155011483 0.49 ENST00000489090.1
RP11-451G4.2
chr12_+_32687221 0.48 ENST00000525053.1
FYVE, RhoGEF and PH domain containing 4
chr9_+_109685630 0.48 ENST00000451160.2
Uncharacterized protein
chr11_-_93271058 0.48 ENST00000527149.1
single-pass membrane protein with coiled-coil domains 4
chr16_+_25123148 0.48 ENST00000570981.1
leucine carboxyl methyltransferase 1
chr5_-_148442584 0.47 ENST00000394358.2
ENST00000512049.1
SH3 domain and tetratricopeptide repeats 2
chr1_-_160231451 0.46 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr13_-_62001982 0.46 ENST00000409186.1
protocadherin 20
chr16_+_19619083 0.45 ENST00000538552.1
chromosome 16 open reading frame 62
chr7_+_80275621 0.45 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr17_-_80797886 0.44 ENST00000572562.1
zinc finger protein 750
chr7_-_107204918 0.43 ENST00000297135.3
component of oligomeric golgi complex 5
chr7_+_80275953 0.43 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr7_+_80275752 0.43 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr10_+_60759378 0.41 ENST00000432535.1
long intergenic non-protein coding RNA 844
chr11_+_46366918 0.41 ENST00000528615.1
ENST00000395574.3
diacylglycerol kinase, zeta
chr18_+_68002675 0.41 ENST00000584919.1
Uncharacterized protein
chr3_-_67705006 0.40 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
succinate-CoA ligase, GDP-forming, beta subunit
chr2_+_120687335 0.40 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr18_+_3252206 0.40 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_12524965 0.40 ENST00000471923.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr6_-_138833630 0.40 ENST00000533765.1
NHS-like 1
chr12_+_19389814 0.40 ENST00000536974.1
pleckstrin homology domain containing, family A member 5
chr5_+_98109322 0.39 ENST00000513185.1
repulsive guidance molecule family member b
chr6_+_118869452 0.39 ENST00000357525.5
phospholamban
chr10_+_24755416 0.38 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr3_+_57875711 0.38 ENST00000442599.2
sarcolemma associated protein
chr11_+_27062860 0.37 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_+_25123041 0.37 ENST00000399069.3
ENST00000380966.4
leucine carboxyl methyltransferase 1
chr4_-_48683188 0.37 ENST00000505759.1
FRY-like
chr11_+_22688150 0.37 ENST00000454584.2
growth arrest-specific 2
chr1_+_89246647 0.37 ENST00000544045.1
protein kinase N2
chr16_+_56782118 0.37 ENST00000566678.1
nucleoporin 93kDa
chr2_+_210443993 0.37 ENST00000392193.1
microtubule-associated protein 2
chr17_-_39646116 0.36 ENST00000328119.6
keratin 36
chr18_+_3252265 0.36 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_45686457 0.36 ENST00000441606.2
anoctamin 6
chr1_+_220267429 0.36 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_+_38662960 0.35 ENST00000524193.1
transforming, acidic coiled-coil containing protein 1
chr10_+_76871229 0.35 ENST00000372690.3
sterile alpha motif domain containing 8
chr14_-_72458326 0.35 ENST00000542853.1
AC005477.1
chr10_-_127505167 0.35 ENST00000368786.1
uroporphyrinogen III synthase
chr12_-_95774672 0.35 ENST00000549961.1
Uncharacterized protein
chr9_+_2029019 0.35 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_171757346 0.33 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
fibronectin type III domain containing 3B
chr3_-_196911002 0.33 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr5_-_58295712 0.33 ENST00000317118.8
phosphodiesterase 4D, cAMP-specific
chr15_+_35270552 0.33 ENST00000391457.2
HCG37415; PRO1914; Uncharacterized protein
chr9_-_95055923 0.32 ENST00000430417.1
isoleucyl-tRNA synthetase
chr10_+_85933494 0.31 ENST00000372126.3
chromosome 10 open reading frame 99
chr6_+_143759575 0.30 ENST00000595616.1
AL031320.1
chr14_+_53173910 0.30 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr7_+_135710494 0.30 ENST00000440744.2
AC024084.1
chr15_+_67835517 0.29 ENST00000395476.2
mitogen-activated protein kinase kinase 5
chr2_-_176046391 0.29 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr16_-_25122735 0.28 ENST00000563176.1
RP11-449H11.1
chr12_-_118796971 0.28 ENST00000542902.1
TAO kinase 3
chrX_-_135962923 0.27 ENST00000565438.1
RNA binding motif protein, X-linked
chr10_-_5660118 0.27 ENST00000427341.1
RP11-336A10.4
chr14_+_53173890 0.27 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_+_57875738 0.27 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr6_+_158733692 0.26 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr11_+_12302492 0.26 ENST00000533534.1
MICAL C-terminal like
chr2_-_95787738 0.26 ENST00000272418.2
mitochondrial ribosomal protein S5
chr9_-_130889990 0.26 ENST00000449878.1
prostaglandin E synthase 2
chr9_-_73029540 0.25 ENST00000377126.2
Kruppel-like factor 9
chr11_+_22688615 0.25 ENST00000533363.1
growth arrest-specific 2
chr20_-_25320367 0.25 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr3_+_41241596 0.24 ENST00000450969.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr20_-_56647116 0.24 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
chr5_+_72143988 0.24 ENST00000506351.2
transportin 1
chr11_+_89764274 0.24 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chr8_+_107738343 0.24 ENST00000521592.1
oxidation resistance 1
chr6_-_133035185 0.24 ENST00000367928.4
vanin 1
chr1_-_54355430 0.24 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
Yip1 domain family, member 1
chr1_-_198990166 0.23 ENST00000427439.1
RP11-16L9.3
chr15_-_41836441 0.23 ENST00000567866.1
ENST00000561603.1
ENST00000304330.4
ENST00000566863.1
RNA polymerase II associated protein 1
chr2_-_8977714 0.23 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
kinase D-interacting substrate, 220kDa
chr13_+_24144509 0.23 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr9_-_37384431 0.23 ENST00000452923.1
RP11-397D12.4
chr9_-_95055956 0.23 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr12_-_10962767 0.23 ENST00000240691.2
taste receptor, type 2, member 9
chr4_+_95972822 0.23 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr2_+_108863651 0.22 ENST00000329106.2
ENST00000376700.1
sulfotransferase family, cytosolic, 1C, member 3
chr20_+_2276639 0.22 ENST00000381458.5
transglutaminase 3
chr19_+_21106028 0.21 ENST00000597314.1
ENST00000601924.1
zinc finger protein 85
chr12_-_76879852 0.21 ENST00000548341.1
oxysterol binding protein-like 8
chr6_-_26189304 0.21 ENST00000340756.2
histone cluster 1, H4d
chr8_+_85095013 0.21 ENST00000522613.1
RALY RNA binding protein-like
chr3_+_15045419 0.21 ENST00000406272.2
nuclear receptor subfamily 2, group C, member 2
chrX_+_107037451 0.20 ENST00000372379.2
nuclear cap binding protein subunit 2-like
chrX_-_135962876 0.20 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr15_+_86686953 0.20 ENST00000421325.2
ATP/GTP binding protein-like 1
chr5_-_148033693 0.20 ENST00000377888.3
ENST00000360693.3
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr2_+_210444298 0.19 ENST00000445941.1
microtubule-associated protein 2
chr2_+_208423840 0.19 ENST00000539789.1
cAMP responsive element binding protein 1
chr7_+_137761167 0.18 ENST00000432161.1
aldo-keto reductase family 1, member D1
chr12_+_1800179 0.18 ENST00000357103.4
adiponectin receptor 2
chr9_-_95056010 0.18 ENST00000443024.2
isoleucyl-tRNA synthetase
chr14_+_35514323 0.17 ENST00000555211.1
family with sequence similarity 177, member A1
chr7_+_6121296 0.17 ENST00000428901.1
AC004895.4
chr11_+_71900703 0.17 ENST00000393681.2
folate receptor 1 (adult)
chr5_-_16738451 0.17 ENST00000274203.9
ENST00000515803.1
myosin X
chr12_+_64173583 0.17 ENST00000261234.6
transmembrane protein 5
chr1_+_46152886 0.17 ENST00000372025.4
transmembrane protein 69
chr1_+_53480598 0.17 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr8_+_52730143 0.17 ENST00000415643.1
Uncharacterized protein
chr8_-_86162077 0.16 ENST00000551479.1
Uncharacterized protein
chr12_-_72104152 0.16 ENST00000549710.1
RP11-498M15.1
chr3_-_156534754 0.16 ENST00000472943.1
ENST00000473352.1
long intergenic non-protein coding RNA 886
chr17_+_68071389 0.16 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_+_47657581 0.16 ENST00000441923.2
anthrax toxin receptor-like
chr9_-_86571628 0.16 ENST00000376344.3
chromosome 9 open reading frame 64
chr20_+_56964169 0.16 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_+_56546223 0.16 ENST00000550443.1
ENST00000207437.5
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr6_+_134274322 0.15 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr21_-_28338732 0.15 ENST00000284987.5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr5_-_111093167 0.15 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr2_+_187371440 0.15 ENST00000445547.1
zinc finger CCCH-type containing 15
chr9_+_134065506 0.15 ENST00000483497.2
nucleoporin 214kDa
chr3_-_123710893 0.15 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
rhophilin associated tail protein 1
chr8_+_145215928 0.15 ENST00000528919.1
maestro heat-like repeat family member 1
chr6_-_127840453 0.14 ENST00000556132.1
SOGA family member 3
chr2_+_151485403 0.14 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
AC104777.4
chr2_+_233415363 0.14 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
eukaryotic translation initiation factor 4E family member 2
chr8_-_143859197 0.14 ENST00000395192.2
Ly6/neurotoxin 1
chr14_+_52456327 0.13 ENST00000556760.1
chromosome 14 open reading frame 166
chr7_-_111032971 0.13 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_65996599 0.13 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
chr2_+_208423891 0.13 ENST00000448277.1
ENST00000457101.1
cAMP responsive element binding protein 1
chr4_+_26165074 0.13 ENST00000512351.1
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_56546363 0.13 ENST00000551834.1
ENST00000552568.1
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr4_+_70894130 0.13 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chr12_-_118796910 0.13 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr16_+_66613351 0.13 ENST00000379486.2
ENST00000268595.2
CKLF-like MARVEL transmembrane domain containing 2
chr19_-_53636125 0.12 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
zinc finger protein 415
chr2_+_109204743 0.12 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr19_+_13885252 0.12 ENST00000221576.4
chromosome 19 open reading frame 53

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042214 terpene metabolic process(GO:0042214)
0.3 0.8 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 1.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 3.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.6 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) receptor-mediated virion attachment to host cell(GO:0046813)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.7 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.8 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.6 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 1.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 1.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 1.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.5 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0044691 tooth eruption(GO:0044691)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) vascular wound healing(GO:0061042)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 0.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 0.8 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 1.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.3 1.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.7 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0052853 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.1 1.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells