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Illumina Body Map 2: averaged replicates

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Results for CEBPE_CEBPD

Z-value: 3.43

Motif logo

Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
ENSG00000092067.5 CEBPE
ENSG00000221869.4 CEBPD

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPEhg19_v2_chr14_-_23588816_235888360.202.8e-01Click!
CEBPDhg19_v2_chr8_-_48651648_486516480.096.4e-01Click!

Activity profile of CEBPE_CEBPD motif

Sorted Z-values of CEBPE_CEBPD motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_133055815 24.10 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr6_-_133055896 22.87 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr12_-_96390108 20.71 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr12_-_96390063 17.91 ENST00000541929.1
HAL
histidine ammonia-lyase
chr3_+_186330712 16.54 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr15_+_58430368 16.51 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr3_+_186383741 15.62 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr15_+_58430567 15.31 ENST00000536493.1
AQP9
aquaporin 9
chr16_+_72088376 13.82 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr11_+_18287801 13.62 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_18287721 13.38 ENST00000356524.4
SAA1
serum amyloid A1
chr10_-_82049424 13.12 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr11_-_18270182 12.72 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr4_+_104346194 12.21 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chrX_+_138612889 12.04 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr2_+_113885138 9.74 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr3_+_186435137 9.74 ENST00000447445.1
KNG1
kininogen 1
chr14_-_70263979 9.51 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr3_+_186435065 9.03 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr1_+_196743912 8.84 ENST00000367425.4
CFHR3
complement factor H-related 3
chrX_-_105282712 8.72 ENST00000372563.1
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr17_-_7018128 8.51 ENST00000380952.2
ENST00000254850.7
ASGR2
asialoglycoprotein receptor 2
chr17_-_7017968 8.40 ENST00000355035.5
ASGR2
asialoglycoprotein receptor 2
chr6_+_31895287 8.36 ENST00000447952.2
C2
complement component 2
chr5_+_49963239 8.31 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr3_-_148939835 8.17 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr1_+_192127578 8.16 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr3_-_58200398 7.99 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_196743943 7.86 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr4_-_155511887 7.69 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr19_+_6887571 7.49 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr6_+_31895254 7.47 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr3_+_46395219 7.19 ENST00000445132.2
ENST00000292301.4
CCR2
chemokine (C-C motif) receptor 2
chr21_-_46334186 7.01 ENST00000522931.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_219247021 6.88 ENST00000539932.1
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr3_-_148939598 6.76 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr20_-_22566089 6.71 ENST00000377115.4
FOXA2
forkhead box A2
chr1_+_196857144 6.42 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr13_-_46679144 6.42 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679185 6.25 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr6_+_31895480 5.98 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chrX_-_131547596 5.93 ENST00000538204.1
ENST00000370849.3
MBNL3
muscleblind-like splicing regulator 3
chr4_+_156775910 5.92 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr17_-_34417479 5.90 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr3_+_46395579 5.85 ENST00000421659.1
CCR2
chemokine (C-C motif) receptor 2
chrX_-_131547625 5.75 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr14_-_23284703 5.66 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_-_39364586 5.60 ENST00000263408.4
C9
complement component 9
chr4_-_185747188 5.40 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_-_31637560 5.39 ENST00000379416.3
XDH
xanthine dehydrogenase
chr6_+_31895467 5.36 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr16_-_84651673 5.36 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr2_+_219246746 5.29 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr13_-_29292956 5.24 ENST00000266943.6
SLC46A3
solute carrier family 46, member 3
chr16_-_84651647 5.20 ENST00000564057.1
COTL1
coactosin-like 1 (Dictyostelium)
chr6_-_24489842 5.17 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr1_+_40862501 5.17 ENST00000539317.1
SMAP2
small ArfGAP2
chr16_-_30457048 5.15 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr11_-_18258342 5.12 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr1_+_154378049 4.97 ENST00000512471.1
IL6R
interleukin 6 receptor
chr19_-_41356347 4.96 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr14_+_20937538 4.91 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr19_+_11350278 4.85 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr1_-_1711508 4.83 ENST00000378625.1
NADK
NAD kinase
chr14_-_23284675 4.80 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_61245363 4.73 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr3_-_10547192 4.60 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr11_+_63057412 4.41 ENST00000544661.1
SLC22A10
solute carrier family 22, member 10
chr11_-_116663127 4.35 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr5_+_49962772 4.29 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr12_-_96389702 4.20 ENST00000552509.1
HAL
histidine ammonia-lyase
chr5_-_138718973 4.14 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr19_-_40971643 4.11 ENST00000595483.1
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr19_+_41497178 4.09 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr14_-_23285011 4.08 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr20_+_56136136 4.00 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr10_+_30723045 3.92 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr8_-_6735451 3.91 ENST00000297439.3
DEFB1
defensin, beta 1
chr14_-_23285069 3.84 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_144339738 3.83 ENST00000538264.1
AL592284.1
Protein LOC642441
chr1_-_111743285 3.75 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr3_-_120400960 3.73 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr3_-_190580404 3.73 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr11_-_58980342 3.73 ENST00000361050.3
MPEG1
macrophage expressed 1
chr10_-_113943447 3.73 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_-_47697387 3.67 ENST00000371884.2
TAL1
T-cell acute lymphocytic leukemia 1
chr15_+_45926919 3.65 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr17_-_77813186 3.57 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr19_-_41388657 3.35 ENST00000301146.4
ENST00000291764.3
CYP2A7
cytochrome P450, family 2, subfamily A, polypeptide 7
chr1_+_207262170 3.35 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr1_+_209941942 3.33 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr6_-_112194484 3.25 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_169887827 3.23 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr7_-_36764004 3.22 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr3_+_16306837 3.21 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr11_-_14993819 3.13 ENST00000396372.2
ENST00000361010.3
ENST00000359642.3
ENST00000331587.4
CALCA
calcitonin-related polypeptide alpha
chr17_+_7477040 3.13 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr11_-_102595681 3.12 ENST00000236826.3
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr19_-_6670128 3.11 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr1_+_154377669 3.10 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr3_-_151102529 3.04 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr17_+_27369918 3.04 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr10_+_30723533 3.02 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr3_+_133465228 2.98 ENST00000482271.1
ENST00000264998.3
TF
transferrin
chr14_-_64971288 2.95 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr3_+_16306691 2.93 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr1_-_204183071 2.90 ENST00000308302.3
GOLT1A
golgi transport 1A
chr14_+_64971292 2.88 ENST00000358738.3
ENST00000394712.2
ZBTB1
zinc finger and BTB domain containing 1
chr3_+_108541608 2.80 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr7_+_137761199 2.71 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr14_-_45722605 2.71 ENST00000310806.4
MIS18BP1
MIS18 binding protein 1
chr19_-_52148798 2.70 ENST00000534261.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr20_+_54987168 2.65 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr7_+_128784712 2.65 ENST00000289407.4
TSPAN33
tetraspanin 33
chr16_-_21663919 2.59 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr19_-_40971667 2.58 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr5_-_140013275 2.58 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr20_+_54987305 2.56 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr16_-_21663950 2.54 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr1_+_209941827 2.54 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr5_-_140013224 2.53 ENST00000498971.2
CD14
CD14 molecule
chr7_-_87936195 2.50 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4
STEAP family member 4
chr9_-_130712995 2.50 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chrY_+_2709527 2.44 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr9_-_94186131 2.41 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr5_-_140013241 2.39 ENST00000519715.1
CD14
CD14 molecule
chr14_+_21423611 2.36 ENST00000304625.2
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr2_-_101925055 2.35 ENST00000295317.3
RNF149
ring finger protein 149
chr22_+_40297079 2.31 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chrX_-_73512177 2.21 ENST00000603672.1
ENST00000418855.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr22_+_40297105 2.18 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chr2_-_209118974 2.15 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr1_-_67519782 2.15 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr10_+_30723105 2.10 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr14_-_106573756 2.09 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chrX_-_73511908 2.06 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr20_-_17662878 1.96 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1
ribosome binding protein 1
chr12_-_123201337 1.96 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr14_+_64971438 1.95 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr14_-_45722360 1.93 ENST00000451174.1
MIS18BP1
MIS18 binding protein 1
chr19_-_6720686 1.92 ENST00000245907.6
C3
complement component 3
chr19_+_50922187 1.90 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_-_156721502 1.84 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr14_+_52313833 1.83 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_151032040 1.81 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr4_+_71263599 1.78 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr14_+_22990951 1.78 ENST00000390515.1
TRAJ22
T cell receptor alpha joining 22
chr6_-_113754604 1.75 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr8_+_8559406 1.74 ENST00000519106.1
CLDN23
claudin 23
chr17_-_34524157 1.71 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr14_+_22947861 1.69 ENST00000390482.1
TRAJ57
T cell receptor alpha joining 57
chr17_-_79817091 1.68 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr20_-_1600642 1.66 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chr1_-_52521831 1.66 ENST00000371626.4
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr2_-_178128199 1.65 ENST00000449627.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr20_-_33732952 1.65 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr11_-_64510409 1.63 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_97416400 1.63 ENST00000371224.2
ENST00000371221.3
ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr17_-_34625719 1.58 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr5_+_137722255 1.58 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr11_-_102595512 1.57 ENST00000438475.2
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr3_+_88188254 1.56 ENST00000309495.5
ZNF654
zinc finger protein 654
chr7_-_121944491 1.56 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr1_+_162531294 1.56 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chrX_-_40506766 1.53 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38
chromosome X open reading frame 38
chr5_-_10761206 1.53 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr15_+_81293254 1.51 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr4_-_186732241 1.46 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_92951607 1.45 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr22_-_20731541 1.45 ENST00000292729.8
USP41
ubiquitin specific peptidase 41
chr14_-_38028689 1.43 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr7_+_150065278 1.42 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr3_+_136649311 1.42 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr8_+_77318769 1.41 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr14_-_107199464 1.40 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr10_+_90750378 1.39 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr8_+_71485681 1.35 ENST00000391684.1
AC120194.1
AC120194.1
chr17_+_7462103 1.34 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_-_123187890 1.34 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chrX_+_24483338 1.30 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr9_+_130860810 1.26 ENST00000433501.1
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_-_77185094 1.26 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr11_-_18062872 1.23 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr11_-_104905840 1.22 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr14_-_23292596 1.22 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_48949030 1.19 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr9_+_130860583 1.18 ENST00000373064.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr5_-_169407744 1.17 ENST00000377365.3
FAM196B
family with sequence similarity 196, member B
chr9_-_99381660 1.15 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr2_-_99279928 1.14 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr7_-_141401951 1.11 ENST00000536163.1
KIAA1147
KIAA1147
chr17_+_7462031 1.11 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_-_10605929 1.10 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr17_-_60142609 1.10 ENST00000397786.2
MED13
mediator complex subunit 13
chr2_-_191878162 1.10 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr5_+_95997885 1.08 ENST00000511097.2
CAST
calpastatin
chr11_+_82868030 1.07 ENST00000298281.4
ENST00000530660.1
PCF11
PCF11 cleavage and polyadenylation factor subunit
chr2_+_64069459 1.07 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr5_+_156696362 1.06 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_186649543 1.06 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 42.8 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
6.1 12.2 GO:0055073 cadmium ion homeostasis(GO:0055073)
5.8 35.0 GO:0015722 canalicular bile acid transport(GO:0015722)
4.6 13.8 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
4.3 13.0 GO:2000409 astrocyte chemotaxis(GO:0035700) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) positive regulation of T cell extravasation(GO:2000409) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
4.1 16.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
3.3 13.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
3.2 12.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.6 46.3 GO:0015939 pantothenate metabolic process(GO:0015939)
2.0 19.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.9 5.6 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.7 5.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
1.7 6.7 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.6 4.9 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
1.5 12.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
1.5 3.0 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.5 5.9 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.4 23.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.4 4.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.4 5.5 GO:0002384 hepatic immune response(GO:0002384)
1.3 5.4 GO:0046110 xanthine metabolic process(GO:0046110)
1.3 5.2 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
1.2 5.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.2 3.7 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
1.2 9.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.2 4.8 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
1.1 7.5 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.0 3.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.0 3.9 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.9 4.4 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.9 26.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.8 5.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.8 3.3 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.8 63.6 GO:0006953 acute-phase response(GO:0006953)
0.8 3.9 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.7 2.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.7 4.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 8.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.6 3.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6 6.7 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5 2.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.5 1.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.5 2.4 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.5 1.9 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 1.4 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.5 3.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5 15.8 GO:0006825 copper ion transport(GO:0006825)
0.4 8.0 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.4 3.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.4 3.0 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 4.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 5.4 GO:0034201 response to oleic acid(GO:0034201)
0.4 3.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 2.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 3.8 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.3 3.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 1.7 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3 4.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.3 2.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 7.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.3 0.6 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.3 11.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 3.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 5.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 3.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 4.4 GO:0015747 urate transport(GO:0015747)
0.2 10.9 GO:0050832 defense response to fungus(GO:0050832)
0.2 1.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 2.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.2 0.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 0.6 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 1.6 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 9.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 3.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 1.2 GO:0046223 mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2 16.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 1.6 GO:0072718 response to cisplatin(GO:0072718)
0.1 1.7 GO:0034378 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) chylomicron assembly(GO:0034378) positive regulation of viral entry into host cell(GO:0046598)
0.1 1.3 GO:0061052 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.4 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 1.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 4.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 9.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.3 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 1.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 2.4 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 8.3 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1 0.2 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 1.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 4.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 1.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 2.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 3.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 2.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.9 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 8.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 3.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 4.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.4 GO:0072376 protein activation cascade(GO:0072376)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 1.1 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.8 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.2 GO:0002292 T cell differentiation involved in immune response(GO:0002292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.2 8.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
1.0 49.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.9 7.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.8 7.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.7 6.0 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.7 3.9 GO:1990742 microvesicle(GO:1990742)
0.6 8.8 GO:0005577 fibrinogen complex(GO:0005577)
0.4 15.6 GO:0036019 endolysosome(GO:0036019)
0.4 3.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 1.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4 2.9 GO:0097179 protease inhibitor complex(GO:0097179)
0.3 80.3 GO:0072562 blood microparticle(GO:0072562)
0.3 4.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 3.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.6 GO:0035102 PRC1 complex(GO:0035102)
0.2 39.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 14.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 60.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 3.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 0.6 GO:0043219 lateral loop(GO:0043219)
0.1 2.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 8.8 GO:0043195 terminal bouton(GO:0043195)
0.1 2.8 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 16.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.3 GO:0071437 invadopodium(GO:0071437)
0.1 5.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 5.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.8 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 9.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 6.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 2.4 GO:0005844 polysome(GO:0005844)
0.0 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.4 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 5.4 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 10.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 42.8 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
7.8 47.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
6.4 31.8 GO:0015254 glycerol channel activity(GO:0015254)
4.1 12.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
3.2 9.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
2.7 8.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
2.6 13.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.3 13.8 GO:0030492 hemoglobin binding(GO:0030492)
1.9 16.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.7 5.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.7 6.7 GO:0004074 biliverdin reductase activity(GO:0004074)
1.6 4.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.4 4.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.4 9.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.3 4.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.3 3.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.2 3.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.1 13.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.1 3.2 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
1.1 7.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.0 3.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
1.0 5.9 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.0 5.9 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.9 19.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.8 3.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.8 44.8 GO:0042056 chemoattractant activity(GO:0042056)
0.8 3.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.7 2.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.6 4.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.6 5.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.6 7.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 2.7 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.5 12.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.5 3.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 15.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 5.4 GO:0004630 phospholipase D activity(GO:0004630)
0.4 3.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.4 2.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 2.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 2.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 1.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.3 35.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 9.8 GO:0001848 complement binding(GO:0001848)
0.3 1.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 4.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 4.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 12.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.6 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 9.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 5.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 2.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 6.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 5.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 3.6 GO:0032183 SUMO binding(GO:0032183)
0.1 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0070052 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.1 4.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 13.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.4 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 6.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 33.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.5 GO:0070513 death domain binding(GO:0070513)
0.1 1.0 GO:0015293 symporter activity(GO:0015293)
0.1 3.1 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 6.3 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 9.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.3 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.3 GO:0089720 caspase binding(GO:0089720)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 3.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 3.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.6 GO:0019843 rRNA binding(GO:0019843)
0.0 5.8 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 4.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 9.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 34.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 35.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 13.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 3.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 14.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 5.5 ST STAT3 PATHWAY STAT3 Pathway
0.2 12.1 PID IL1 PATHWAY IL1-mediated signaling events
0.2 14.8 PID BMP PATHWAY BMP receptor signaling
0.1 2.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 10.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 14.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 5.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 9.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 6.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 16.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 3.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 3.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 31.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.5 49.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.2 30.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.8 27.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 12.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 27.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 10.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 9.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 7.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 8.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 7.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 16.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 14.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 4.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 19.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 5.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 15.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 3.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 6.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 5.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 6.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 37.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 20.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 9.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 7.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 6.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 8.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.2 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 3.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 4.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 7.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII