Motif ID: CREB3L2

Z-value: 1.646


Transcription factors associated with CREB3L2:

Gene SymbolEntrez IDGene Name
CREB3L2 ENSG00000182158.10 CREB3L2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB3L2hg19_v2_chr7_-_137686791_137686821-0.028.9e-01Click!


Activity profile for motif CREB3L2.

activity profile for motif CREB3L2


Sorted Z-values histogram for motif CREB3L2

Sorted Z-values for motif CREB3L2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB3L2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_61584026 4.060 ENST00000370351.4
ENST00000370349.3
SLC17A9

solute carrier family 17 (vesicular nucleotide transporter), member 9

chr20_+_61584398 3.395 ENST00000411611.1
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr19_-_4670345 2.494 ENST00000599630.1
ENST00000262947.3
C19orf10

chromosome 19 open reading frame 10

chr20_-_22559211 2.392 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr17_-_26695013 2.267 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 2.065 ENST00000438614.1
VTN
vitronectin
chr9_+_96928516 1.834 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr12_-_49318715 1.830 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr14_+_100789669 1.811 ENST00000361529.3
ENST00000557052.1
SLC25A47

solute carrier family 25, member 47

chr5_+_34656569 1.762 ENST00000428746.2
RAI14
retinoic acid induced 14
chr5_+_34656529 1.663 ENST00000513974.1
ENST00000512629.1
RAI14

retinoic acid induced 14

chr1_-_32801825 1.643 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_+_34656331 1.600 ENST00000265109.3
RAI14
retinoic acid induced 14
chr20_-_61051026 1.586 ENST00000252997.2
GATA5
GATA binding protein 5
chr10_+_102106829 1.544 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr7_-_100171270 1.541 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr14_-_106174960 1.521 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_106054659 1.436 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr20_+_31595406 1.413 ENST00000170150.3
BPIFB2
BPI fold containing family B, member 2
chr10_+_23216944 1.410 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3


armadillo repeat containing 3


chr8_+_22225041 1.409 ENST00000289952.5
ENST00000524285.1
SLC39A14

solute carrier family 39 (zinc transporter), member 14

chr18_+_56806701 1.404 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr2_+_217498105 1.394 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr22_+_22681656 1.387 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr9_+_130478345 1.379 ENST00000373289.3
ENST00000393748.4
TTC16

tetratricopeptide repeat domain 16

chr3_+_122785895 1.360 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr8_+_22224760 1.322 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr19_-_11688500 1.315 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr20_-_2821271 1.310 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr5_-_138725594 1.300 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr18_+_56807096 1.298 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr18_+_9708162 1.294 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr19_-_42759300 1.260 ENST00000222329.4
ERF
Ets2 repressor factor
chr15_+_89181974 1.253 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_151561506 1.245 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_23217006 1.244 ENST00000376528.4
ENST00000447081.1
ARMC3

armadillo repeat containing 3

chr17_+_72270429 1.241 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr2_-_85108164 1.200 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr22_+_44568825 1.198 ENST00000422871.1
PARVG
parvin, gamma
chr5_-_138725560 1.197 ENST00000412103.2
ENST00000457570.2
MZB1

marginal zone B and B1 cell-specific protein

chr18_-_3013307 1.196 ENST00000584294.1
LPIN2
lipin 2
chr22_+_38864041 1.162 ENST00000216014.4
ENST00000409006.3
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr14_+_101293687 1.161 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr15_+_58724184 1.151 ENST00000433326.2
LIPC
lipase, hepatic
chr10_+_112257596 1.143 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr2_+_198365095 1.121 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr15_+_89182156 1.117 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_+_89419370 1.112 ENST00000361175.4
ENST00000456849.1
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr21_+_45875354 1.060 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr3_+_184098065 1.058 ENST00000348986.3
CHRD
chordin
chr5_+_34656450 1.056 ENST00000514527.1
RAI14
retinoic acid induced 14
chr2_-_85108363 1.055 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr6_+_151561085 1.053 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_85108240 1.049 ENST00000409133.1
TRABD2A
TraB domain containing 2A
chr19_-_47164386 1.018 ENST00000391916.2
ENST00000410105.2
DACT3

dishevelled-binding antagonist of beta-catenin 3

chr5_+_176730769 1.013 ENST00000303204.4
ENST00000503216.1
PRELID1

PRELI domain containing 1

chr1_-_27240455 0.992 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_-_7911042 0.977 ENST00000379757.4
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr15_+_89182178 0.964 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_37455536 0.964 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chr6_-_136871957 0.959 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr17_+_48450575 0.949 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1


essential meiotic structure-specific endonuclease 1


chr7_+_29603394 0.949 ENST00000319694.2
PRR15
proline rich 15
chr11_+_120081475 0.936 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr1_+_1567474 0.930 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr3_-_123603137 0.909 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr7_-_6523755 0.890 ENST00000258739.4
ENST00000436575.1
KDELR2
DAGLB
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase, beta
chr3_-_178789220 0.886 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr21_-_18985158 0.847 ENST00000339775.6
BTG3
BTG family, member 3
chr1_-_42921915 0.832 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr15_-_52404921 0.817 ENST00000561198.1
ENST00000260442.3
BCL2L10

BCL2-like 10 (apoptosis facilitator)

chr15_+_62359175 0.816 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr21_-_40720995 0.815 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr1_-_241520525 0.802 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr8_+_56014949 0.797 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr19_+_49458107 0.779 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX






BCL2-associated X protein






chr12_+_121416489 0.778 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr21_-_18985230 0.776 ENST00000457956.1
ENST00000348354.6
BTG3

BTG family, member 3

chr6_-_32811771 0.762 ENST00000395339.3
ENST00000374882.3
PSMB8

proteasome (prosome, macropain) subunit, beta type, 8

chr20_-_4795747 0.758 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr7_+_2671568 0.724 ENST00000258796.7
TTYH3
tweety family member 3
chr19_+_12305895 0.723 ENST00000451691.2
CTD-2666L21.1
CTD-2666L21.1
chr8_-_99129338 0.722 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr16_+_215965 0.719 ENST00000356815.3
HBM
hemoglobin, mu
chrX_+_128913906 0.718 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr19_-_11688951 0.712 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr12_+_121416340 0.699 ENST00000257555.6
ENST00000400024.2
HNF1A

HNF1 homeobox A

chr21_-_40720974 0.696 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr16_-_67185117 0.694 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr19_+_51774540 0.691 ENST00000600813.1
CTD-3187F8.11
CTD-3187F8.11
chr1_+_113392455 0.686 ENST00000456651.1
ENST00000422022.1
RP3-522D1.1

RP3-522D1.1

chr2_-_198364581 0.679 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr13_+_98794810 0.679 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr8_-_99129384 0.675 ENST00000521560.1
ENST00000254878.3
HRSP12

heat-responsive protein 12

chr1_-_11865982 0.673 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_11866207 0.660 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr3_-_57583185 0.657 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr7_+_100464760 0.655 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr1_-_91317072 0.649 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1

RP4-665J23.1

chr1_+_28918712 0.647 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr17_+_74723031 0.644 ENST00000586200.1
METTL23
methyltransferase like 23
chr7_-_121036337 0.639 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C


family with sequence similarity 3, member C


chr19_+_11350278 0.632 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr14_-_100070363 0.632 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr20_+_44519948 0.631 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr12_+_50355647 0.631 ENST00000293599.6
AQP5
aquaporin 5
chr3_-_57583052 0.626 ENST00000496292.1
ENST00000489843.1
ARF4

ADP-ribosylation factor 4

chr11_+_45944190 0.625 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B



glycosyltransferase-like 1B



chr7_-_98030360 0.623 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr19_+_51774520 0.616 ENST00000595566.1
ENST00000594261.1
CTD-3187F8.11

CTD-3187F8.11

chr2_+_207024306 0.610 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2



eukaryotic translation elongation factor 1 beta 2



chr10_-_97416400 0.604 ENST00000371224.2
ENST00000371221.3
ALDH18A1

aldehyde dehydrogenase 18 family, member A1

chr22_+_39916558 0.603 ENST00000337304.2
ENST00000396680.1
ATF4

activating transcription factor 4

chr10_+_103892787 0.601 ENST00000278070.2
ENST00000413464.2
PPRC1

peroxisome proliferator-activated receptor gamma, coactivator-related 1

chrX_-_48326764 0.599 ENST00000413668.1
ENST00000441948.1
SLC38A5

solute carrier family 38, member 5

chr3_-_57583130 0.597 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chrX_+_131157290 0.594 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr20_+_44520009 0.585 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr11_-_118972575 0.583 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr9_+_117350009 0.560 ENST00000374050.3
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr15_-_79383102 0.558 ENST00000558480.2
ENST00000419573.3
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr19_-_39805976 0.556 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr12_+_121416437 0.555 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A



HNF1 homeobox A



chr17_-_74722536 0.551 ENST00000585429.1
JMJD6
jumonji domain containing 6
chrX_-_48326683 0.547 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chrX_+_131157322 0.544 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4


Serine/threonine-protein kinase MST4


chr2_+_46926048 0.541 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr20_-_17662878 0.540 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chrX_+_55246771 0.540 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chrX_+_153686614 0.533 ENST00000369682.3
PLXNA3
plexin A3
chr2_-_65357225 0.533 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A




RAB1A, member RAS oncogene family




chr10_-_127464390 0.531 ENST00000368808.3
MMP21
matrix metallopeptidase 21
chrX_+_55246818 0.529 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr5_+_133984462 0.515 ENST00000398844.2
ENST00000322887.4
SEC24A

SEC24 family member A

chr11_-_57282349 0.511 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr3_+_51428704 0.506 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr7_-_6523688 0.498 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr7_+_16793160 0.489 ENST00000262067.4
TSPAN13
tetraspanin 13
chr19_-_40730820 0.487 ENST00000513948.1
CNTD2
cyclin N-terminal domain containing 2
chr2_+_113403434 0.479 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr20_-_44519839 0.463 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr20_-_2821756 0.460 ENST00000356872.3
ENST00000439542.1
PCED1A

PC-esterase domain containing 1A

chr2_+_241526126 0.456 ENST00000391984.2
ENST00000391982.2
ENST00000404753.3
ENST00000270364.7
ENST00000352879.4
ENST00000354082.4
CAPN10





calpain 10





chr17_+_39969183 0.454 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_111746966 0.454 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr8_-_143696833 0.450 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr11_+_32112431 0.450 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_+_74722912 0.438 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23










methyltransferase like 23










chr5_+_68710906 0.428 ENST00000325631.5
ENST00000454295.2
MARVELD2

MARVEL domain containing 2

chr19_-_13030071 0.427 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr6_+_32811861 0.424 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr6_-_28891709 0.419 ENST00000377194.3
ENST00000377199.3
TRIM27

tripartite motif containing 27

chr5_-_158636512 0.417 ENST00000424310.2
RNF145
ring finger protein 145
chr8_-_144679264 0.414 ENST00000531953.1
ENST00000526133.1
EEF1D

eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)

chr22_-_35627045 0.409 ENST00000423311.1
CTA-714B7.5
CTA-714B7.5
chr15_-_52030293 0.409 ENST00000560491.1
ENST00000267838.3
LYSMD2

LysM, putative peptidoglycan-binding, domain containing 2

chr7_-_8301869 0.404 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr6_+_167684651 0.402 ENST00000503433.1
UNC93A
unc-93 homolog A (C. elegans)
chr4_+_186347388 0.397 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr1_-_1167411 0.394 ENST00000263741.7
SDF4
stromal cell derived factor 4
chr1_-_11866034 0.393 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_155572164 0.381 ENST00000392845.3
ENST00000359479.3
SLC33A1

solute carrier family 33 (acetyl-CoA transporter), member 1

chr5_+_68711023 0.380 ENST00000515844.1
MARVELD2
MARVEL domain containing 2
chr22_-_18257178 0.378 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr10_+_131265443 0.372 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr21_-_28215332 0.371 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_+_201676908 0.369 ENST00000409226.1
ENST00000452790.2
BZW1

basic leucine zipper and W2 domains 1

chr11_-_777467 0.368 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1




Parkinson disease 7 domain containing 1




chr5_-_176730676 0.367 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24


RAB24, member RAS oncogene family


chr11_+_67159416 0.362 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr1_+_180123969 0.362 ENST00000367602.3
ENST00000367600.5
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr9_-_136242956 0.357 ENST00000371989.3
ENST00000485435.2
SURF4

surfeit 4

chr7_-_8302164 0.353 ENST00000447326.1
ENST00000406470.2
ICA1

islet cell autoantigen 1, 69kDa

chr21_+_37442239 0.349 ENST00000530908.1
ENST00000290349.6
ENST00000439427.2
ENST00000399191.3
CBR1



carbonyl reductase 1



chr7_+_23749945 0.347 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
STK31



serine/threonine kinase 31



chr9_+_130565147 0.341 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS



folylpolyglutamate synthase



chr11_+_67776012 0.331 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr6_+_32811885 0.328 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1




PSMB9
TAP1 and PSMB8 antisense RNA 1




proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_152870215 0.324 ENST00000518142.1
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr19_-_44143939 0.323 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr11_-_100999775 0.322 ENST00000263463.5
PGR
progesterone receptor
chr16_-_28074822 0.322 ENST00000395724.3
ENST00000380898.2
ENST00000447459.2
GSG1L


GSG1-like


chr15_-_40213080 0.321 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr16_+_2533020 0.320 ENST00000562105.1
TBC1D24
TBC1 domain family, member 24
chr11_-_111957451 0.318 ENST00000504148.2
ENST00000541231.1
TIMM8B

translocase of inner mitochondrial membrane 8 homolog B (yeast)

chr2_+_201676256 0.312 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1


basic leucine zipper and W2 domains 1


chr4_+_119200215 0.310 ENST00000602573.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr1_+_110162448 0.301 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2



adenosine monophosphate deaminase 2



chr12_+_57623869 0.300 ENST00000414700.3
ENST00000557703.1
SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

chr7_-_8301682 0.300 ENST00000396675.3
ENST00000430867.1
ICA1

islet cell autoantigen 1, 69kDa

chr10_+_6392278 0.291 ENST00000391437.1
DKFZP667F0711
DKFZP667F0711
chr19_-_10341948 0.291 ENST00000592342.1
ENST00000588952.1
ENST00000590320.1
DNMT1

S1PR2
DNA (cytosine-5-)-methyltransferase 1

sphingosine-1-phosphate receptor 2
chr10_-_49459800 0.288 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr11_-_61560053 0.283 ENST00000537328.1
TMEM258
transmembrane protein 258
chr1_-_45956822 0.283 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr12_+_57623477 0.282 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2


serine hydroxymethyltransferase 2 (mitochondrial)


chr1_+_228327943 0.279 ENST00000366726.1
ENST00000312726.4
ENST00000366728.2
ENST00000453943.1
ENST00000366723.1
ENST00000366722.1
ENST00000435153.1
ENST00000366721.1
GUK1







guanylate kinase 1







chr6_-_144329384 0.277 ENST00000417959.2
PLAGL1
pleiomorphic adenoma gene-like 1
chr2_-_27341966 0.275 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1


cell growth regulator with EF-hand domain 1


chr3_+_51741072 0.249 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035623 renal glucose absorption(GO:0035623)
0.7 3.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 2.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 1.1 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 1.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.3 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 0.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 2.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 0.7 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.2 2.7 GO:0006465 signal peptide processing(GO:0006465)
0.2 2.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 1.2 GO:0034337 RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.6 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.9 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.1 0.5 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 1.4 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 2.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.5 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.1 GO:0001706 endoderm formation(GO:0001706)
0.1 2.3 GO:0018208 peptidyl-proline modification(GO:0018208)
0.1 1.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 1.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 1.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0009650 UV protection(GO:0009650)
0.0 1.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 1.5 GO:0048678 response to axon injury(GO:0048678)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 1.2 GO:0042384 cilium assembly(GO:0042384)
0.0 0.4 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.0 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) activation of cysteine-type endopeptidase activity(GO:0097202)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.0 0.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.3 GO:0006066 alcohol metabolic process(GO:0006066)
0.0 0.6 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 1.0 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.5 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 2.0 GO:0045120 pronucleus(GO:0045120)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.0 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 2.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.3 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.0 7.9 GO:0005938 cell cortex(GO:0005938)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.9 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0005624 obsolete membrane fraction(GO:0005624)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0008859 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.4 1.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.3 2.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.1 GO:0045545 syndecan binding(GO:0045545)
0.2 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.5 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.2 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.5 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.3 GO:0048039 succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039)
0.1 1.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 2.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 2.0 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 3.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004461 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 1.2 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton