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Illumina Body Map 2: averaged replicates

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Results for CUX1

Z-value: 2.26

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
CUX1
ENSG00000257923.5 cut like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX1hg19_v2_chr7_+_101459263_101459310-0.476.6e-03Click!

Activity profile of CUX1 motif

Sorted Z-values of CUX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_22448819 6.99 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr1_+_161676739 6.76 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr1_+_161677034 5.92 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr19_-_7764960 5.88 ENST00000593418.1
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr2_+_7865923 5.62 ENST00000417930.1
AC092580.4
AC092580.4
chr1_+_161676983 4.86 ENST00000367957.2
FCRLA
Fc receptor-like A
chrX_+_78426469 4.66 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr22_+_23241661 4.61 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr1_+_151129103 4.49 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr11_-_118213360 4.45 ENST00000529594.1
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr14_-_106453155 4.28 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr7_+_142448053 4.16 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr7_-_142131914 4.09 ENST00000390375.2
TRBV5-6
T cell receptor beta variable 5-6
chr3_-_112218205 3.89 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr3_-_112218378 3.88 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr7_+_142326335 3.70 ENST00000390393.3
TRBV19
T cell receptor beta variable 19
chr14_-_106322288 3.69 ENST00000390559.2
IGHM
immunoglobulin heavy constant mu
chr22_+_23077065 3.68 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr22_-_37545972 3.52 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr12_-_55378452 3.46 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr19_-_10628117 3.25 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr2_+_90259593 3.10 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr6_+_31554962 3.09 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr2_+_90139056 3.08 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr22_+_22786288 3.07 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr6_+_31554826 3.02 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr5_-_66492562 2.94 ENST00000256447.4
CD180
CD180 molecule
chr14_-_106331652 2.92 ENST00000390565.1
IGHJ1
immunoglobulin heavy joining 1
chr2_-_89278535 2.92 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90153696 2.91 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr22_+_23235872 2.91 ENST00000390320.2
IGLJ1
immunoglobulin lambda joining 1
chr11_+_118175596 2.91 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr1_-_157670528 2.89 ENST00000368186.5
ENST00000496769.1
FCRL3
Fc receptor-like 3
chr14_-_106330458 2.88 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr22_+_22712087 2.86 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr14_-_106092403 2.85 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr12_-_53601000 2.80 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr11_-_111320706 2.76 ENST00000531398.1
POU2AF1
POU class 2 associating factor 1
chr22_+_22697537 2.72 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr16_+_32859034 2.68 ENST00000567458.2
ENST00000560724.1
IGHV2OR16-5
immunoglobulin heavy variable 2/OR16-5 (non-functional)
chr11_+_118175132 2.67 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chrX_-_70331298 2.61 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr2_+_90229045 2.61 ENST00000390278.2
IGKV1D-42
immunoglobulin kappa variable 1D-42 (non-functional)
chr1_-_27953031 2.53 ENST00000374003.3
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr14_-_107283278 2.52 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr22_+_23243156 2.51 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr7_-_142139783 2.43 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6
chr7_-_142207004 2.43 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr7_+_142378566 2.41 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr7_-_142176790 2.41 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr19_-_42133420 2.38 ENST00000221954.2
ENST00000600925.1
CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
chr7_+_142031986 2.37 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr16_+_27413483 2.31 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr14_+_22788560 2.29 ENST00000390468.1
TRAV41
T cell receptor alpha variable 41
chr17_-_38721711 2.24 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr17_-_43502987 2.21 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr19_-_51875523 2.19 ENST00000593572.1
ENST00000595157.1
NKG7
natural killer cell group 7 sequence
chr22_+_22676808 2.16 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr7_+_142012967 2.15 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chr14_-_106725723 2.15 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr2_-_158300556 2.11 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr22_+_22385332 2.09 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr4_-_48136217 2.09 ENST00000264316.4
TXK
TXK tyrosine kinase
chr1_-_36948879 2.08 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr11_-_58980342 2.08 ENST00000361050.3
MPEG1
macrophage expressed 1
chr7_-_142198049 2.07 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr22_-_37640277 2.07 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_+_23165153 2.05 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr12_+_7060508 2.05 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr13_-_28674693 2.04 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
FLT3
fms-related tyrosine kinase 3
chr11_+_67171548 2.03 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr14_-_25045446 2.03 ENST00000216336.2
CTSG
cathepsin G
chr22_+_22730353 2.00 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr16_+_33006369 1.98 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_+_22965872 1.97 ENST00000390495.1
TRAJ42
T cell receptor alpha joining 42
chr13_-_46716969 1.97 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_106068065 1.96 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr12_-_55378470 1.95 ENST00000524668.1
ENST00000533607.1
TESPA1
thymocyte expressed, positive selection associated 1
chr14_+_22771851 1.94 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr19_-_10450328 1.94 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr22_+_23040274 1.93 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr12_+_7060414 1.93 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_159466136 1.89 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr7_-_142120321 1.86 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr14_+_23009190 1.84 ENST00000390532.1
TRAJ5
T cell receptor alpha joining 5
chr12_+_8666126 1.84 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr14_-_65785502 1.84 ENST00000553754.1
CTD-2509G16.5
CTD-2509G16.5
chr7_-_38403077 1.84 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr19_-_54784353 1.84 ENST00000391746.1
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_-_113594279 1.83 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr14_-_25103388 1.83 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_+_158901329 1.83 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr12_+_7060432 1.83 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_86268065 1.83 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr1_-_151032040 1.83 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr22_+_22516550 1.82 ENST00000390284.2
IGLV4-60
immunoglobulin lambda variable 4-60
chr12_-_54689532 1.82 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr1_+_206730484 1.77 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr4_-_48116540 1.77 ENST00000506073.1
TXK
TXK tyrosine kinase
chr16_-_85784634 1.77 ENST00000284245.4
ENST00000602914.1
C16orf74
chromosome 16 open reading frame 74
chr7_-_142224280 1.76 ENST00000390367.3
TRBV11-1
T cell receptor beta variable 11-1
chr6_-_159466042 1.75 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr17_-_72358001 1.71 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr7_+_142364193 1.71 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr7_-_3083573 1.70 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr17_-_47287928 1.70 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr16_+_27438563 1.69 ENST00000395754.4
IL21R
interleukin 21 receptor
chr21_+_10862622 1.66 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr1_-_27952617 1.65 ENST00000457296.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr17_-_72542278 1.64 ENST00000330793.1
CD300C
CD300c molecule
chr19_+_55084438 1.64 ENST00000439534.1
LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr11_-_118095718 1.64 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr22_+_50986462 1.64 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr19_-_10450287 1.63 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr11_-_118095801 1.63 ENST00000356289.5
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr9_+_130478345 1.63 ENST00000373289.3
ENST00000393748.4
TTC16
tetratricopeptide repeat domain 16
chr14_+_22970526 1.61 ENST00000390498.1
TRAJ39
T cell receptor alpha joining 39
chr5_+_57787254 1.60 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GAPT
GRB2-binding adaptor protein, transmembrane
chr7_-_1980128 1.60 ENST00000437877.1
MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
chr15_-_31523036 1.59 ENST00000559094.1
ENST00000558388.2
RP11-16E12.2
RP11-16E12.2
chr17_-_7018128 1.59 ENST00000380952.2
ENST00000254850.7
ASGR2
asialoglycoprotein receptor 2
chr16_+_31366536 1.59 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr9_-_136344237 1.59 ENST00000432868.1
ENST00000371899.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr14_+_21359558 1.58 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr1_-_27952741 1.58 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr17_-_7017968 1.56 ENST00000355035.5
ASGR2
asialoglycoprotein receptor 2
chr5_-_156362666 1.55 ENST00000406964.1
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr11_+_67171358 1.54 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr7_-_142251148 1.53 ENST00000390360.3
TRBV6-4
T cell receptor beta variable 6-4
chr19_+_55085248 1.51 ENST00000391738.3
ENST00000251376.3
ENST00000391737.1
ENST00000396321.2
ENST00000418536.2
ENST00000448689.1
LILRA2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr2_+_28853443 1.51 ENST00000436775.1
PLB1
phospholipase B1
chr2_-_158182410 1.49 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr18_-_67629015 1.47 ENST00000579496.1
CD226
CD226 molecule
chr14_+_22971215 1.47 ENST00000390499.1
TRAJ38
T cell receptor alpha joining 38
chr8_+_27168988 1.44 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr6_+_391739 1.41 ENST00000380956.4
IRF4
interferon regulatory factor 4
chrX_-_30595959 1.41 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr14_+_22987424 1.41 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr2_-_96811170 1.41 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr5_-_131826457 1.40 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr9_-_136344197 1.40 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr17_-_74489215 1.40 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr19_-_54876414 1.39 ENST00000474878.1
ENST00000348231.4
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr12_-_21487829 1.38 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr14_+_22636283 1.35 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chr1_+_156117149 1.34 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_36973406 1.34 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr19_+_35645817 1.34 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr1_+_158801095 1.33 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chrX_+_48542168 1.33 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr17_-_18950310 1.32 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr6_-_32498046 1.32 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr13_-_46961317 1.32 ENST00000322896.6
KIAA0226L
KIAA0226-like
chr6_+_32811861 1.32 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr1_+_156119798 1.31 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_+_42427826 1.30 ENST00000586443.1
GRN
granulin
chr5_-_157002749 1.29 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr5_-_131347583 1.29 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr22_+_37318082 1.27 ENST00000406230.1
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr17_+_19030782 1.27 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr7_+_74188309 1.27 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr11_+_62037622 1.27 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chr12_+_7055631 1.27 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_+_51630287 1.26 ENST00000599948.1
SIGLEC9
sialic acid binding Ig-like lectin 9
chr6_+_36683256 1.26 ENST00000229824.8
RAB44
RAB44, member RAS oncogene family
chr7_+_26191809 1.25 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr10_-_14613968 1.25 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr3_+_172361483 1.24 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr3_+_142842128 1.24 ENST00000483262.1
RP11-80H8.4
RP11-80H8.4
chr10_-_98480243 1.23 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr2_-_158182322 1.22 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr19_-_54604083 1.22 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr5_-_157002775 1.21 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr13_+_30510003 1.18 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr1_+_48688357 1.17 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr7_-_36764062 1.17 ENST00000435386.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr11_+_36317830 1.15 ENST00000530639.1
PRR5L
proline rich 5 like
chr12_+_6898674 1.14 ENST00000541982.1
ENST00000539492.1
CD4
CD4 molecule
chr1_-_183560011 1.14 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr1_+_111773349 1.13 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr1_-_156786634 1.13 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr17_-_5487768 1.12 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr20_+_58571419 1.11 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr19_+_5681153 1.11 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr14_-_106963409 1.11 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr11_+_35222629 1.11 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr19_-_54824344 1.10 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr10_-_14614122 1.09 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr5_+_176784837 1.08 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr16_-_776431 1.07 ENST00000293889.6
CCDC78
coiled-coil domain containing 78
chrX_-_47489244 1.06 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr6_-_32820529 1.05 ENST00000425148.2
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_-_149465990 1.05 ENST00000543093.1
CSF1R
colony stimulating factor 1 receptor
chr17_+_6900201 1.04 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr6_-_32812420 1.04 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr6_+_31554612 1.04 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr7_-_139727118 1.03 ENST00000484111.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr10_-_14614095 1.03 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr19_-_10628098 1.03 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr1_+_161632937 1.03 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
1.1 5.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.0 5.9 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.9 1.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.9 2.6 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.9 2.6 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.8 5.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.8 6.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.7 2.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.6 4.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.6 3.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.6 1.8 GO:0001694 histamine biosynthetic process(GO:0001694)
0.6 2.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5 2.6 GO:0031296 B cell costimulation(GO:0031296)
0.5 1.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.5 1.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.4 3.4 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.4 1.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.4 3.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 28.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 2.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 1.3 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.3 7.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 4.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.3 1.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.3 2.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.3 1.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 1.3 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.3 0.8 GO:1901656 glycoside transport(GO:1901656)
0.2 1.5 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.2 1.9 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 1.0 GO:0060032 notochord regression(GO:0060032)
0.2 0.7 GO:0061582 colon epithelial cell migration(GO:0061580) intestinal epithelial cell migration(GO:0061582)
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 4.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 1.1 GO:0035150 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.2 1.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.4 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 1.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 1.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 1.2 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.7 GO:0060018 astrocyte fate commitment(GO:0060018)
0.2 3.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 0.9 GO:0071400 cellular response to oleic acid(GO:0071400)
0.2 1.0 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of extrathymic T cell differentiation(GO:0033082)
0.2 0.7 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.2 1.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 2.6 GO:0060263 regulation of respiratory burst(GO:0060263)
0.2 0.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.2 33.9 GO:0002377 immunoglobulin production(GO:0002377)
0.2 0.8 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.7 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.6 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.9 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 11.8 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 5.2 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.1 1.7 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 1.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 4.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:1904970 brush border assembly(GO:1904970)
0.1 0.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 2.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 10.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 2.2 GO:0045730 respiratory burst(GO:0045730)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 1.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.7 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.6 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.7 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 9.6 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 3.5 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 1.1 GO:0090197 regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1 0.3 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.2 GO:0046041 ITP metabolic process(GO:0046041)
0.1 1.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.2 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 1.0 GO:0015816 glycine transport(GO:0015816)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 1.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 2.0 GO:0097186 amelogenesis(GO:0097186)
0.1 1.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 8.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.8 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:0070839 spleen trabecula formation(GO:0060345) divalent metal ion export(GO:0070839) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 4.0 GO:0030101 natural killer cell activation(GO:0030101)
0.0 9.4 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.6 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.9 GO:0002449 lymphocyte mediated immunity(GO:0002449)
0.0 0.7 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 2.3 GO:0006968 cellular defense response(GO:0006968)
0.0 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.3 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 2.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.6 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:2000288 positive regulation of skeletal muscle tissue regeneration(GO:0043415) positive regulation of myoblast proliferation(GO:2000288)
0.0 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.3 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 1.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 17.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 2.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 25.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.3 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.3 3.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.0 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.3 1.1 GO:0072534 perineuronal net(GO:0072534)
0.2 1.7 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 2.4 GO:0032010 phagolysosome(GO:0032010)
0.2 3.1 GO:0033269 internode region of axon(GO:0033269)
0.2 1.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 1.1 GO:0098536 deuterosome(GO:0098536)
0.2 1.1 GO:0042825 TAP complex(GO:0042825)
0.2 1.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 2.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 3.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 5.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 8.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 1.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 4.9 GO:0016235 aggresome(GO:0016235)
0.1 2.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 7.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 21.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.0 GO:0005902 microvillus(GO:0005902)
0.1 1.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 3.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 5.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 3.7 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.1 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.8 5.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 6.8 GO:0019863 IgE binding(GO:0019863)
0.6 2.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.5 27.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 1.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 3.4 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.4 2.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.4 3.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.4 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.3 5.6 GO:0042608 T cell receptor binding(GO:0042608)
0.3 9.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 0.9 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.3 1.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 1.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 0.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 1.6 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3 1.3 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 1.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 1.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.7 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 47.0 GO:0003823 antigen binding(GO:0003823)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.2 GO:0015081 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) sodium ion transmembrane transporter activity(GO:0015081)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.7 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 0.9 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 1.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0042806 fucose binding(GO:0042806)
0.1 2.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 5.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 3.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 2.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 4.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 3.3 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 3.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.5 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 2.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.6 GO:0042835 BRE binding(GO:0042835)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 1.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.3 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 1.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.8 GO:0019864 IgG binding(GO:0019864)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 3.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.1 GO:0004568 chitinase activity(GO:0004568)
0.1 1.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 1.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0003774 motor activity(GO:0003774)
0.1 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 0.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:1902444 riboflavin binding(GO:1902444)
0.0 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 4.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 2.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 3.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 5.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.7 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.8 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.3 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 4.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 21.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 4.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 6.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 22.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 5.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 4.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 17.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 7.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 8.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 2.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 4.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 5.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 2.8 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.5 REACTOME CELL CYCLE CHECKPOINTS Genes involved in Cell Cycle Checkpoints
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery