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Illumina Body Map 2: averaged replicates

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Results for DLX3_EVX1_MEOX1

Z-value: 0.92

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Transcription factors associated with DLX3_EVX1_MEOX1

Gene Symbol Gene ID Gene Info
ENSG00000064195.7 distal-less homeobox 3
ENSG00000106038.8 even-skipped homeobox 1
ENSG00000005102.8 mesenchyme homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEOX1hg19_v2_chr17_-_41738931_417390400.212.4e-01Click!
EVX1hg19_v2_chr7_+_27282319_27282394-0.183.1e-01Click!
DLX3hg19_v2_chr17_-_48072574_480725970.048.1e-01Click!

Activity profile of DLX3_EVX1_MEOX1 motif

Sorted Z-values of DLX3_EVX1_MEOX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_6233828 1.40 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr4_-_36245561 1.38 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_22748980 1.37 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr5_-_115890554 1.34 ENST00000509665.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_-_111424462 1.18 ENST00000437129.1
dedicator of cytokinesis 4
chr13_+_58206655 1.17 ENST00000377918.3
protocadherin 17
chr6_+_151646800 1.14 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr4_-_138453606 1.09 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr7_-_111424506 1.07 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr18_-_53019208 1.05 ENST00000562607.1
transcription factor 4
chr19_-_47137942 0.96 ENST00000300873.4
guanine nucleotide binding protein (G protein), gamma 8
chr7_-_99716914 0.90 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_-_46716969 0.90 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_109541610 0.89 ENST00000510212.1
RPL34 antisense RNA 1 (head to head)
chr7_-_14029283 0.86 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr15_-_64673630 0.85 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr18_-_53255379 0.84 ENST00000565908.2
transcription factor 4
chr10_-_56561022 0.81 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr3_+_111718036 0.77 ENST00000455401.2
transgelin 3
chr15_-_55562479 0.76 ENST00000564609.1
RAB27A, member RAS oncogene family
chr3_+_111717600 0.74 ENST00000273368.4
transgelin 3
chr3_+_111717511 0.74 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr14_+_59100774 0.72 ENST00000556859.1
ENST00000421793.1
dishevelled-binding antagonist of beta-catenin 1
chr7_+_80255472 0.71 ENST00000428497.1
CD36 molecule (thrombospondin receptor)
chr13_-_36788718 0.70 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr17_-_46716647 0.69 ENST00000608940.1
RP11-357H14.17
chr15_-_55562582 0.69 ENST00000396307.2
RAB27A, member RAS oncogene family
chrX_+_99839799 0.65 ENST00000373031.4
tenomodulin
chr8_-_82395461 0.65 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr3_+_2933893 0.65 ENST00000397459.2
contactin 4
chr6_+_130339710 0.63 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr3_+_115342349 0.61 ENST00000393780.3
growth associated protein 43
chrX_-_13835147 0.61 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr14_+_22739823 0.60 ENST00000390464.2
T cell receptor alpha variable 38-1
chr15_-_55563072 0.60 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr18_-_44181442 0.60 ENST00000398722.4
lipoxygenase homology domains 1
chr22_+_22930626 0.58 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr17_-_38928414 0.58 ENST00000335552.4
keratin 26
chr13_+_110958124 0.58 ENST00000400163.2
collagen, type IV, alpha 2
chr7_-_14028488 0.57 ENST00000405358.4
ets variant 1
chr14_-_36988882 0.55 ENST00000498187.2
NK2 homeobox 1
chr1_-_157746909 0.55 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
Fc receptor-like 2
chrX_-_18690210 0.54 ENST00000379984.3
retinoschisin 1
chr7_-_83824449 0.53 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_+_14280564 0.53 ENST00000572567.1
MKL/myocardin-like 2
chr7_+_80253387 0.52 ENST00000438020.1
CD36 molecule (thrombospondin receptor)
chr6_+_135502501 0.52 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr3_+_111718173 0.52 ENST00000494932.1
transgelin 3
chr4_+_40198527 0.52 ENST00000381799.5
ras homolog family member H
chr15_-_64673665 0.52 ENST00000300035.4
KIAA0101
chr8_-_10512569 0.51 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr7_-_83824169 0.51 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr15_-_55562451 0.50 ENST00000568803.1
RAB27A, member RAS oncogene family
chr1_+_202317815 0.50 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr7_-_81399355 0.50 ENST00000457544.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_-_138453559 0.49 ENST00000511115.1
protocadherin 18
chr6_-_32157947 0.49 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr1_-_21625486 0.47 ENST00000481130.2
endothelin converting enzyme 1
chr15_+_75080883 0.47 ENST00000567571.1
c-src tyrosine kinase
chr4_-_109541539 0.46 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34 antisense RNA 1 (head to head)
chr10_+_118187379 0.46 ENST00000369230.3
pancreatic lipase-related protein 3
chr12_-_53045948 0.46 ENST00000309680.3
keratin 2
chr2_-_224467093 0.45 ENST00000305409.2
secretogranin II
chr20_+_45947246 0.44 ENST00000599904.1
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr10_-_73848086 0.43 ENST00000536168.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_+_7865923 0.43 ENST00000417930.1
AC092580.4
chr3_-_3151664 0.42 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
interleukin 5 receptor, alpha
chr12_-_52995291 0.41 ENST00000293745.2
ENST00000354310.4
keratin 72
chr5_-_141249154 0.41 ENST00000357517.5
ENST00000536585.1
protocadherin 1
chr5_+_173930676 0.41 ENST00000504512.1
RP11-267A15.1
chr13_-_28545276 0.41 ENST00000381020.7
caudal type homeobox 2
chr2_+_169757750 0.40 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr7_-_27169801 0.40 ENST00000511914.1
homeobox A4
chr2_+_196313239 0.40 ENST00000413290.1
AC064834.1
chrX_+_135730297 0.40 ENST00000370629.2
CD40 ligand
chr1_+_198608146 0.38 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr1_-_232651312 0.38 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr6_+_127898312 0.38 ENST00000329722.7
chromosome 6 open reading frame 58
chr4_-_25865159 0.38 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_-_33913708 0.37 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr1_+_160370344 0.36 ENST00000368061.2
VANGL planar cell polarity protein 2
chr2_-_224467002 0.36 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr7_+_129906660 0.36 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr11_+_128563652 0.35 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_116833500 0.35 ENST00000356128.4
trafficking protein particle complex 3-like
chr6_+_126221034 0.35 ENST00000433571.1
nuclear receptor coactivator 7
chr1_-_183622442 0.34 ENST00000308641.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr13_-_30683005 0.34 ENST00000413591.1
ENST00000432770.1
long intergenic non-protein coding RNA 365
chr7_+_99717230 0.34 ENST00000262932.3
canopy FGF signaling regulator 4
chr9_-_75488984 0.34 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
chr11_-_40315640 0.34 ENST00000278198.2
leucine rich repeat containing 4C
chr3_+_2553281 0.33 ENST00000434053.1
contactin 4
chr7_-_81399438 0.33 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_83278322 0.32 ENST00000307792.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_107729887 0.32 ENST00000525815.1
solute carrier family 35, member F2
chr2_-_145188137 0.32 ENST00000440875.1
zinc finger E-box binding homeobox 2
chr14_+_97925151 0.32 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
chr6_-_76203454 0.31 ENST00000237172.7
filamin A interacting protein 1
chr3_+_44840679 0.31 ENST00000425755.1
kinesin family member 15
chr6_-_138866823 0.30 ENST00000342260.5
NHS-like 1
chr14_-_95236551 0.30 ENST00000238558.3
goosecoid homeobox
chr11_+_115498761 0.30 ENST00000424313.2
AP000997.1
chr6_-_116866773 0.29 ENST00000368602.3
trafficking protein particle complex 3-like
chrX_-_100129128 0.29 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NADPH oxidase 1
chr12_+_15699286 0.29 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr6_+_46761118 0.28 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr1_+_198608292 0.28 ENST00000418674.1
protein tyrosine phosphatase, receptor type, C
chr7_-_81399329 0.28 ENST00000453411.1
ENST00000444829.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_107683436 0.28 ENST00000370068.1
netrin G1
chr11_-_107729287 0.28 ENST00000375682.4
solute carrier family 35, member F2
chr12_-_89746264 0.28 ENST00000548755.1
dual specificity phosphatase 6
chr11_-_107729504 0.28 ENST00000265836.7
solute carrier family 35, member F2
chr3_-_123339343 0.28 ENST00000578202.1
myosin light chain kinase
chrX_+_78426469 0.27 ENST00000276077.1
G protein-coupled receptor 174
chr14_-_92247032 0.27 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr1_+_198607801 0.27 ENST00000367379.1
protein tyrosine phosphatase, receptor type, C
chr4_-_176812842 0.27 ENST00000507540.1
glycoprotein M6A
chr15_-_31393910 0.27 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
transient receptor potential cation channel, subfamily M, member 1
chr3_-_108248169 0.27 ENST00000273353.3
myosin, heavy chain 15
chr6_-_31107127 0.26 ENST00000259845.4
psoriasis susceptibility 1 candidate 2
chr12_-_68619586 0.26 ENST00000229134.4
interleukin 26
chr2_-_203735484 0.26 ENST00000420558.1
ENST00000418208.1
islet cell autoantigen 1,69kDa-like
chr11_-_117748138 0.26 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr14_+_62585332 0.25 ENST00000554895.1
long intergenic non-protein coding RNA 643
chr12_-_89746173 0.25 ENST00000308385.6
dual specificity phosphatase 6
chr7_+_50348268 0.25 ENST00000438033.1
ENST00000439701.1
IKAROS family zinc finger 1 (Ikaros)
chr11_-_117747607 0.25 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr11_-_117747434 0.24 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr1_+_107683644 0.24 ENST00000370067.1
netrin G1
chr7_-_81399411 0.23 ENST00000423064.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_100860851 0.23 ENST00000223127.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr7_-_14029515 0.23 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr12_+_8666126 0.23 ENST00000299665.2
C-type lectin domain family 4, member D
chr3_+_77088989 0.23 ENST00000461745.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr3_+_155755482 0.23 ENST00000472028.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr2_+_158114051 0.23 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr14_+_22180536 0.23 ENST00000390424.2
T cell receptor alpha variable 2
chr5_-_34043310 0.22 ENST00000231338.7
C1q and tumor necrosis factor related protein 3
chr19_-_7968427 0.22 ENST00000539278.1
Uncharacterized protein
chr12_-_94673956 0.22 ENST00000551941.1
Uncharacterized protein
chr16_+_14280742 0.22 ENST00000341243.5
MKL/myocardin-like 2
chr13_-_30160925 0.22 ENST00000450494.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_-_56560939 0.22 ENST00000373955.1
protocadherin-related 15
chr19_-_4902877 0.21 ENST00000381781.2
arrestin domain containing 5
chr4_-_120243545 0.21 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr4_-_46126093 0.21 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr2_-_99279928 0.21 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_54893250 0.21 ENST00000397862.2
chromosome 17 open reading frame 67
chr16_-_67517716 0.20 ENST00000290953.2
agouti related protein homolog (mouse)
chr18_-_56985776 0.20 ENST00000587244.1
complexin 4
chr4_-_87028478 0.20 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr14_+_22564294 0.19 ENST00000390452.2
T cell receptor delta variable 1
chr17_-_57229155 0.19 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr3_-_195538760 0.19 ENST00000475231.1
mucin 4, cell surface associated
chr1_+_111415757 0.19 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr15_+_80351910 0.19 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr1_+_50575292 0.19 ENST00000371821.1
ENST00000371819.1
ELAV like neuron-specific RNA binding protein 4
chr8_+_70404996 0.18 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr12_-_14133053 0.18 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr14_-_69261310 0.18 ENST00000336440.3
ZFP36 ring finger protein-like 1
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr4_-_66536057 0.18 ENST00000273854.3
EPH receptor A5
chr14_+_101359265 0.18 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr3_-_100565249 0.18 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI family, member 3 (NESH) binding protein
chr19_+_50016610 0.18 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr4_-_48683188 0.18 ENST00000505759.1
FRY-like
chrX_-_110655306 0.18 ENST00000371993.2
doublecortin
chr20_+_3776371 0.18 ENST00000245960.5
cell division cycle 25B
chr11_-_67220200 0.18 ENST00000312457.2
G protein-coupled receptor 152
chr6_+_43968306 0.17 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr3_-_195538728 0.17 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr11_+_101918153 0.17 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chrX_-_19689106 0.17 ENST00000379716.1
SH3-domain kinase binding protein 1
chr9_+_116225999 0.17 ENST00000317613.6
regulator of G-protein signaling 3
chr3_+_185431080 0.17 ENST00000296270.1
chromosome 3 open reading frame 65
chr17_-_39140549 0.17 ENST00000377755.4
keratin 40
chr7_+_37723336 0.17 ENST00000450180.1
G protein-coupled receptor 141
chr11_+_67219867 0.16 ENST00000438189.2
calcium binding protein 4
chr14_-_78083112 0.16 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr10_+_114710425 0.16 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr20_+_42523336 0.16 ENST00000428529.1
RP5-1030M6.3
chr14_+_56584414 0.16 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr6_+_167536230 0.15 ENST00000341935.5
ENST00000349984.4
chemokine (C-C motif) receptor 6
chr1_-_197115818 0.15 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_+_129984630 0.15 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr10_-_105845674 0.15 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr10_-_23633720 0.15 ENST00000323327.4
chromosome 10 open reading frame 67
chr11_-_118083600 0.15 ENST00000524477.1
adhesion molecule, interacts with CXADR antigen 1
chr15_+_96869165 0.15 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr5_+_66300446 0.15 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr8_-_101963482 0.15 ENST00000419477.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_+_152879985 0.15 ENST00000323534.2
RAP2B, member of RAS oncogene family
chr3_-_143567262 0.14 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr14_+_100485712 0.14 ENST00000544450.2
Enah/Vasp-like
chr2_+_219135115 0.14 ENST00000248451.3
ENST00000273077.4
paroxysmal nonkinesigenic dyskinesia
chr12_-_120241187 0.14 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr17_-_48133054 0.14 ENST00000499842.1
RP11-1094H24.4
chr12_+_41831485 0.14 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr2_-_214016314 0.14 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr17_+_59489112 0.14 ENST00000335108.2
chromosome 17 open reading frame 82

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX3_EVX1_MEOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1990709 presynaptic active zone organization(GO:1990709)
0.4 2.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 2.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 1.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.9 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 0.5 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.5 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.4 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.0 GO:0019236 response to pheromone(GO:0019236)
0.1 1.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.7 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 1.2 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 0.7 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.8 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 1.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0048631 negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.2 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 1.0 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031265 death-inducing signaling complex(GO:0031264) CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 2.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 2.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 2.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 3.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation