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Illumina Body Map 2: averaged replicates

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Results for DLX5

Z-value: 1.01

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Transcription factors associated with DLX5

Gene Symbol Gene ID Gene Info
DLX5
ENSG00000105880.4 distal-less homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX5hg19_v2_chr7_-_96654133_966544090.584.6e-04Click!

Activity profile of DLX5 motif

Sorted Z-values of DLX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_124553437 4.11 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr1_+_160160283 2.88 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_+_54378923 2.75 ENST00000303460.4
HOXC10
homeobox C10
chr1_+_160160346 2.71 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr14_+_32798547 2.14 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr12_+_81110684 1.97 ENST00000228644.3
MYF5
myogenic factor 5
chr14_+_32798462 1.90 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr4_+_169575875 1.84 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_186560476 1.72 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_-_105588231 1.68 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr13_-_36050819 1.66 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr3_+_186560462 1.66 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr11_-_102709441 1.66 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_+_54378849 1.44 ENST00000515593.1
HOXC10
homeobox C10
chr1_+_202317815 1.38 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chrX_+_100224676 1.38 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr11_-_26593779 1.30 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr20_-_56647116 1.24 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
RP13-379L11.1
chr11_-_26593677 1.23 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr1_+_202317855 1.22 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr3_+_2933893 1.16 ENST00000397459.2
CNTN4
contactin 4
chr7_+_70597109 1.15 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr10_-_97200772 1.12 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr13_-_36788718 1.06 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr4_-_138453559 1.05 ENST00000511115.1
PCDH18
protocadherin 18
chr11_-_26593649 1.04 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_-_58571935 0.99 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_818902 0.93 ENST00000336615.4
PNPLA2
patatin-like phospholipase domain containing 2
chr3_-_105587879 0.88 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_7013897 0.86 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr1_-_112903150 0.86 ENST00000427290.1
RP5-965F6.2
RP5-965F6.2
chr6_-_78173490 0.85 ENST00000369947.2
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
chr16_-_52061283 0.81 ENST00000566314.1
C16orf97
chromosome 16 open reading frame 97
chr2_+_228736321 0.79 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr13_+_110958124 0.76 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr4_+_175839517 0.74 ENST00000502940.1
ENST00000502305.1
ADAM29
ADAM metallopeptidase domain 29
chr8_-_7332604 0.74 ENST00000316169.2
DEFB104B
defensin, beta 104B
chr9_-_34329198 0.72 ENST00000379166.2
ENST00000345050.2
KIF24
kinesin family member 24
chr12_+_7014064 0.70 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr18_-_33709268 0.70 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr18_-_44181442 0.68 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr20_+_58571419 0.67 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr4_-_74853897 0.64 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr14_-_95236551 0.63 ENST00000238558.3
GSC
goosecoid homeobox
chr11_-_102651343 0.63 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr4_-_143767428 0.62 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_228735763 0.60 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr17_+_43238438 0.60 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr17_+_36508826 0.60 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr7_-_99716940 0.59 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_-_28969517 0.57 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr7_-_99716952 0.56 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr2_+_95963052 0.54 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr3_+_11178779 0.54 ENST00000438284.2
HRH1
histamine receptor H1
chr2_+_169757750 0.52 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr12_+_7014126 0.51 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr12_-_95774672 0.50 ENST00000549961.1
RP11-167N24.6
Uncharacterized protein
chr19_+_36239576 0.49 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr22_-_32860427 0.48 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr7_-_99717463 0.48 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_-_33913708 0.48 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_28268623 0.48 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr12_+_7456880 0.44 ENST00000399422.4
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr16_+_58010339 0.43 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr1_-_197115818 0.43 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_-_86849836 0.42 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr8_-_94179079 0.41 ENST00000521906.1
C8orf87
chromosome 8 open reading frame 87
chr18_-_53255379 0.40 ENST00000565908.2
TCF4
transcription factor 4
chr11_-_123814580 0.36 ENST00000321252.2
OR6T1
olfactory receptor, family 6, subfamily T, member 1
chr1_-_242612779 0.36 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr15_+_63188009 0.36 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr12_+_52695617 0.36 ENST00000293525.5
KRT86
keratin 86
chrX_+_100645812 0.35 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr1_+_61547894 0.34 ENST00000403491.3
NFIA
nuclear factor I/A
chr19_-_36606181 0.34 ENST00000221859.4
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr15_+_89164520 0.34 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr6_-_33256664 0.32 ENST00000444176.1
WDR46
WD repeat domain 46
chr2_-_183387064 0.32 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_-_73051037 0.32 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr1_+_54569968 0.32 ENST00000391366.1
AL161915.1
Uncharacterized protein
chr17_-_38956205 0.31 ENST00000306658.7
KRT28
keratin 28
chr17_+_59489112 0.31 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr8_-_10512569 0.31 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr19_+_58570605 0.31 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135
zinc finger protein 135
chr15_+_41913690 0.30 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr3_-_52567792 0.30 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chr10_-_128110441 0.29 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr4_-_66536057 0.26 ENST00000273854.3
EPHA5
EPH receptor A5
chr4_-_8873531 0.26 ENST00000400677.3
HMX1
H6 family homeobox 1
chr1_-_151762900 0.26 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr13_+_36050881 0.25 ENST00000537702.1
NBEA
neurobeachin
chr1_+_61547405 0.24 ENST00000371189.4
NFIA
nuclear factor I/A
chr1_-_242612726 0.24 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr17_+_42264556 0.23 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr5_-_92023923 0.22 ENST00000503489.1
CTC-529L17.2
CTC-529L17.2
chr13_+_111748183 0.20 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr18_+_63091237 0.20 ENST00000582028.1
RP11-453M23.1
RP11-453M23.1
chr20_+_43849941 0.20 ENST00000372769.3
SEMG2
semenogelin II
chr2_+_228736335 0.19 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr12_-_10978957 0.18 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_-_78444776 0.16 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr3_-_180397256 0.16 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr1_-_150669604 0.15 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr8_+_32579321 0.15 ENST00000522402.1
NRG1
neuregulin 1
chr7_-_7575477 0.14 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr2_+_30369807 0.14 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
YPEL5
yippee-like 5 (Drosophila)
chrX_-_16887963 0.14 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr2_-_183387430 0.14 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr19_+_6372444 0.14 ENST00000245812.3
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr5_-_160279207 0.14 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr8_-_82373809 0.13 ENST00000379071.2
FABP9
fatty acid binding protein 9, testis
chr3_+_194426277 0.13 ENST00000439479.1
AC106706.1
AC106706.1
chr19_+_4007644 0.13 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr6_-_27860956 0.12 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr19_+_36606354 0.11 ENST00000589996.1
ENST00000591296.1
TBCB
tubulin folding cofactor B
chr4_+_66536248 0.10 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr14_-_68283291 0.10 ENST00000555452.1
ENST00000347230.4
ZFYVE26
zinc finger, FYVE domain containing 26
chr4_-_66536196 0.10 ENST00000511294.1
EPHA5
EPH receptor A5
chr8_+_32579271 0.10 ENST00000518084.1
NRG1
neuregulin 1
chr18_+_55888767 0.10 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_+_30369859 0.09 ENST00000402003.3
YPEL5
yippee-like 5 (Drosophila)
chr11_-_26743546 0.08 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr12_-_53171128 0.06 ENST00000332411.2
KRT76
keratin 76
chr17_-_37009882 0.06 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23
ribosomal protein L23
chr17_-_39341594 0.06 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr19_+_54641444 0.06 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr3_-_186288097 0.06 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr7_+_97736197 0.05 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr2_-_220118631 0.05 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr12_+_51818749 0.05 ENST00000514353.3
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr6_+_27861190 0.04 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr1_-_21620877 0.04 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr1_-_78444738 0.03 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.5 9.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.5 4.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 4.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 0.6 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.2 0.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 2.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 1.7 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 2.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.9 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 3.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.5 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 1.7 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.6 GO:0014802 terminal cisterna(GO:0014802)
0.3 4.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 4.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 4.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0071547 piP-body(GO:0071547)
0.0 2.6 GO:0031672 A band(GO:0031672)
0.0 1.8 GO:0002102 podosome(GO:0002102)
0.0 3.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 GO:0033691 sialic acid binding(GO:0033691)
0.2 4.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.6 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.8 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 2.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.1 PID FOXO PATHWAY FoxO family signaling
0.0 2.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 3.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1