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Illumina Body Map 2: averaged replicates

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Results for E2F2_E2F5

Z-value: 1.90

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F transcription factor 2
ENSG00000133740.6 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg19_v2_chr1_-_23857698_238577330.691.3e-05Click!
E2F5hg19_v2_chr8_+_86089619_860896530.412.0e-02Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_36235529 4.40 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr1_-_23857698 4.16 ENST00000361729.2
E2F transcription factor 2
chr2_-_27498186 2.96 ENST00000447008.2
solute carrier family 30 (zinc transporter), member 3
chr20_-_32274179 2.91 ENST00000343380.5
E2F transcription factor 1
chr2_-_235405679 2.70 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr16_-_3030407 2.29 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
protein kinase, membrane associated tyrosine/threonine 1
chr16_-_3030283 2.06 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr2_-_27498208 2.05 ENST00000424577.1
ENST00000426569.1
solute carrier family 30 (zinc transporter), member 3
chr15_+_32907691 1.94 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
Rho GTPase activating protein 11A
chr2_+_174219548 1.88 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr2_+_27498331 1.88 ENST00000402462.1
ENST00000404433.1
ENST00000406962.1
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr22_+_35796108 1.82 ENST00000382011.5
ENST00000416905.1
minichromosome maintenance complex component 5
chr3_+_10857885 1.82 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr12_-_45270077 1.81 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr3_+_44803209 1.77 ENST00000326047.4
kinesin family member 15
chr20_-_35724388 1.74 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr10_+_96305535 1.72 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
helicase, lymphoid-specific
chr12_-_45270151 1.67 ENST00000429094.2
NEL-like 2 (chicken)
chr13_+_32889605 1.64 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr1_-_120612240 1.61 ENST00000256646.2
notch 2
chr2_+_27498289 1.60 ENST00000296097.3
ENST00000420191.1
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr3_+_127317705 1.56 ENST00000480910.1
minichromosome maintenance complex component 2
chr12_-_45269430 1.56 ENST00000395487.2
NEL-like 2 (chicken)
chr20_+_2082494 1.55 ENST00000246032.3
serine/threonine kinase 35
chr22_+_35796056 1.53 ENST00000216122.4
minichromosome maintenance complex component 5
chr1_-_26232522 1.48 ENST00000399728.1
stathmin 1
chr12_-_45269769 1.47 ENST00000548826.1
NEL-like 2 (chicken)
chr3_+_127317066 1.43 ENST00000265056.7
minichromosome maintenance complex component 2
chr10_+_96305610 1.39 ENST00000371332.4
ENST00000239026.6
helicase, lymphoid-specific
chr2_+_10263298 1.37 ENST00000474701.1
ribonucleotide reductase M2
chr22_+_42095497 1.36 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
meiosis inhibitor 1
chr1_-_26232951 1.34 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr6_+_27775899 1.33 ENST00000358739.3
histone cluster 1, H2ai
chr1_-_36235559 1.28 ENST00000251195.5
claspin
chr7_+_50344289 1.26 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKAROS family zinc finger 1 (Ikaros)
chr12_-_12849073 1.24 ENST00000332427.2
ENST00000540796.1
G protein-coupled receptor 19
chr6_+_135502501 1.24 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr7_-_148581251 1.22 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr8_+_94929110 1.21 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_154265784 1.20 ENST00000240488.3
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr15_-_64673630 1.18 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr8_+_94929077 1.16 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr10_+_112327425 1.15 ENST00000361804.4
structural maintenance of chromosomes 3
chr3_-_48229846 1.13 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
cell division cycle 25A
chr2_+_17935119 1.12 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr10_+_13203543 1.10 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr4_+_71859156 1.09 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr20_+_25388293 1.09 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr15_+_40987327 1.09 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr2_+_47168630 1.08 ENST00000263737.6
tetratricopeptide repeat domain 7A
chr6_+_27114861 1.07 ENST00000377459.1
histone cluster 1, H2ah
chr15_-_64673665 1.06 ENST00000300035.4
KIAA0101
chr2_-_219433014 1.05 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr1_+_25598989 1.04 ENST00000454452.2
Rh blood group, D antigen
chr12_-_45269251 1.04 ENST00000553120.1
NEL-like 2 (chicken)
chr17_+_29158962 1.04 ENST00000321990.4
ATPase family, AAA domain containing 5
chr8_+_94929168 1.03 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_17935383 1.03 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr12_-_77459306 1.01 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr1_+_25599018 1.00 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
Rh blood group, D antigen
chr7_+_120590803 0.99 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr5_-_79950371 0.99 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr1_+_151043070 0.99 ENST00000368918.3
ENST00000368917.1
GA binding protein transcription factor, beta subunit 2
chr1_+_212208919 0.98 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_219433281 0.98 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr8_+_94929273 0.96 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_-_79177673 0.94 ENST00000377208.5
POU class 4 homeobox 1
chr7_-_148581360 0.91 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr2_+_219433588 0.91 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_10679644 0.90 ENST00000393599.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr6_-_27782548 0.89 ENST00000333151.3
histone cluster 1, H2aj
chr4_-_130014609 0.88 ENST00000511426.1
sodium channel and clathrin linker 1
chr15_+_40987661 0.88 ENST00000526763.1
RAD51 recombinase
chr10_-_58120996 0.85 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr4_-_130014705 0.84 ENST00000503401.1
sodium channel and clathrin linker 1
chr3_+_10068095 0.84 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr3_+_44803322 0.84 ENST00000481166.2
kinesin family member 15
chr8_-_67525524 0.84 ENST00000517885.1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr8_-_67525473 0.83 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_26233423 0.81 ENST00000357865.2
stathmin 1
chr3_-_53080047 0.79 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr9_-_104500862 0.79 ENST00000361820.3
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr1_+_25598872 0.78 ENST00000328664.4
Rh blood group, D antigen
chr13_-_41768654 0.77 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr4_-_130014729 0.76 ENST00000281142.5
ENST00000434680.1
sodium channel and clathrin linker 1
chr19_-_10679697 0.76 ENST00000335766.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr22_-_38966172 0.76 ENST00000216024.2
DNA meiotic recombinase 1
chr5_-_176738883 0.76 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MAX dimerization protein 3
chr12_-_58131931 0.75 ENST00000547588.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_135502408 0.75 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr9_-_123639445 0.75 ENST00000312189.6
PHD finger protein 19
chr15_-_70388943 0.74 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr2_+_10262857 0.73 ENST00000304567.5
ribonucleotide reductase M2
chr1_+_36038971 0.73 ENST00000373235.3
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr11_+_125495862 0.73 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
checkpoint kinase 1
chr4_-_174256276 0.72 ENST00000296503.5
high mobility group box 2
chr16_-_89007491 0.72 ENST00000327483.5
ENST00000564416.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr20_+_5931497 0.71 ENST00000378886.2
ENST00000265187.4
minichromosome maintenance complex component 8
chrX_+_123095890 0.71 ENST00000435215.1
stromal antigen 2
chr6_-_27806117 0.71 ENST00000330180.2
histone cluster 1, H2ak
chr4_-_130014532 0.70 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
sodium channel and clathrin linker 1
chr16_+_3019552 0.70 ENST00000572687.1
progestin and adipoQ receptor family member IV
chr2_+_47168313 0.70 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
tetratricopeptide repeat domain 7A
chr1_-_23670752 0.70 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chrX_-_131623982 0.69 ENST00000370844.1
muscleblind-like splicing regulator 3
chr9_+_82186682 0.69 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_122238464 0.68 ENST00000546227.1
ras homolog family member F (in filopodia)
chr1_+_66458072 0.68 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr19_-_10305752 0.68 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNA (cytosine-5-)-methyltransferase 1
chr19_+_50094866 0.66 ENST00000418929.2
proline rich 12
chrX_-_131623874 0.66 ENST00000436215.1
muscleblind-like splicing regulator 3
chrX_-_135849484 0.65 ENST00000370620.1
ENST00000535227.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_+_4918342 0.64 ENST00000280684.3
ENST00000433855.1
potassium voltage-gated channel, shaker-related subfamily, member 6
chr2_-_17935027 0.63 ENST00000446852.1
structural maintenance of chromosomes 6
chr6_+_31707725 0.62 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
mutS homolog 5
chr1_+_145209092 0.62 ENST00000362074.6
ENST00000344859.3
notch 2 N-terminal like
chr22_-_38966123 0.62 ENST00000439567.1
DNA meiotic recombinase 1
chr2_-_96700664 0.62 ENST00000359548.4
ENST00000377137.3
ENST00000439254.1
ENST00000453542.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr3_-_133380731 0.62 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr1_-_32801825 0.62 ENST00000329421.7
MARCKS-like 1
chr8_-_98290087 0.62 ENST00000322128.3
TSPY-like 5
chr16_-_85722530 0.61 ENST00000253462.3
GINS complex subunit 2 (Psf2 homolog)
chr5_+_93954358 0.61 ENST00000504099.1
ankyrin repeat domain 32
chr10_+_62538089 0.61 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr7_+_120591170 0.60 ENST00000431467.1
inhibitor of growth family, member 3
chrX_+_75648046 0.59 ENST00000361470.2
melanoma antigen family E, 1
chr19_-_6502590 0.59 ENST00000264071.2
tubulin, beta 4A class IVa
chrX_+_123095860 0.58 ENST00000428941.1
stromal antigen 2
chr18_+_2655849 0.58 ENST00000261598.8
structural maintenance of chromosomes flexible hinge domain containing 1
chr1_-_91487013 0.58 ENST00000347275.5
ENST00000370440.1
zinc finger protein 644
chr15_-_40401062 0.58 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr15_+_44719394 0.57 ENST00000260327.4
ENST00000396780.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_-_105517021 0.56 ENST00000318724.4
ENST00000419735.3
ataxin 7-like 1
chr3_-_14220068 0.56 ENST00000449060.2
ENST00000511155.1
xeroderma pigmentosum, complementation group C
chr6_+_135502466 0.56 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr22_+_35653445 0.56 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr12_-_133263893 0.56 ENST00000535270.1
ENST00000320574.5
polymerase (DNA directed), epsilon, catalytic subunit
chr1_-_23670813 0.55 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr9_-_123639304 0.55 ENST00000436309.1
PHD finger protein 19
chr19_-_10305302 0.55 ENST00000592054.1
DNA (cytosine-5-)-methyltransferase 1
chr1_-_228645556 0.55 ENST00000366695.2
histone cluster 3, H2a
chr5_+_93954039 0.54 ENST00000265140.5
ankyrin repeat domain 32
chrX_+_131157322 0.54 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr5_+_43121698 0.54 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
zinc finger protein 131
chrX_+_131157290 0.54 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr11_+_64808368 0.54 ENST00000531072.1
ENST00000398846.1
SAC3 domain containing 1
chr14_-_50154921 0.54 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr11_-_64739358 0.51 ENST00000301896.5
ENST00000530444.1
chromosome 11 open reading frame 85
chr5_+_36152091 0.51 ENST00000274254.5
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr2_-_17935059 0.50 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr9_+_106856831 0.50 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr8_+_48873479 0.50 ENST00000262105.2
minichromosome maintenance complex component 4
chr7_-_158497431 0.50 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chr11_-_64739542 0.49 ENST00000536065.1
chromosome 11 open reading frame 85
chr3_+_16926441 0.49 ENST00000418129.2
ENST00000396755.2
phospholipase C-like 2
chr15_+_64752927 0.49 ENST00000416172.1
zinc finger protein 609
chr1_-_47779762 0.48 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
SCL/TAL1 interrupting locus
chr1_-_149812765 0.48 ENST00000369158.1
histone cluster 2, H3c
chr15_+_44719790 0.48 ENST00000558791.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_53925063 0.48 ENST00000371445.3
DMRT-like family B with proline-rich C-terminal, 1
chr9_-_35079911 0.47 ENST00000448890.1
Fanconi anemia, complementation group G
chr8_+_48873453 0.47 ENST00000523944.1
minichromosome maintenance complex component 4
chr7_-_100026280 0.47 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr22_+_42394780 0.47 ENST00000328823.9
WBP2 N-terminal like
chrX_+_101906294 0.46 ENST00000361600.5
ENST00000415986.1
ENST00000444152.1
ENST00000537097.1
G protein-coupled receptor associated sorting protein 1
chrX_+_100353153 0.45 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr19_-_6502341 0.45 ENST00000598006.1
ENST00000601152.1
tubulin, beta 4A class IVa
chr1_-_202679535 0.45 ENST00000367268.4
synaptotagmin II
chr9_-_123639600 0.45 ENST00000373896.3
PHD finger protein 19
chr1_-_100598444 0.45 ENST00000535161.1
ENST00000287482.5
spindle assembly 6 homolog (C. elegans)
chr19_-_10444188 0.44 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr9_-_113800705 0.44 ENST00000441240.1
lysophosphatidic acid receptor 1
chr4_-_175750364 0.44 ENST00000340217.5
ENST00000274093.3
glycine receptor, alpha 3
chr5_+_43121607 0.44 ENST00000509156.1
ENST00000508259.1
ENST00000306938.4
ENST00000399534.1
zinc finger protein 131
chr22_-_29137771 0.43 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr17_-_26879567 0.43 ENST00000581945.1
ENST00000444148.1
ENST00000301032.4
ENST00000335765.4
unc-119 homolog (C. elegans)
chrX_+_70798261 0.43 ENST00000373696.3
acidic repeat containing
chr6_+_26045603 0.43 ENST00000540144.1
histone cluster 1, H3c
chr2_+_61108771 0.43 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_-_122758994 0.42 ENST00000306467.5
ENST00000515110.1
centrosomal protein 120kDa
chr5_+_36152179 0.42 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr17_-_57184170 0.42 ENST00000393065.2
tripartite motif containing 37
chr17_-_42580738 0.42 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
G patch domain containing 8
chr9_-_99180597 0.42 ENST00000375256.4
zinc finger protein 367
chr10_+_102672712 0.41 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
family with sequence similarity 178, member A
chr12_-_122238913 0.41 ENST00000537157.1
AC084018.1
chr15_+_44719996 0.40 ENST00000559793.1
ENST00000558968.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_133861790 0.40 ENST00000395003.1
jade family PHD finger 2
chr11_-_118966167 0.40 ENST00000530167.1
H2A histone family, member X
chr9_+_106856541 0.39 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
structural maintenance of chromosomes 2
chr16_-_30102547 0.39 ENST00000279386.2
T-box 6
chr10_+_62538248 0.39 ENST00000448257.2
cyclin-dependent kinase 1
chr1_-_91487770 0.39 ENST00000337393.5
zinc finger protein 644
chr5_+_36876833 0.38 ENST00000282516.8
ENST00000448238.2
Nipped-B homolog (Drosophila)
chr6_+_84569359 0.38 ENST00000369681.5
ENST00000369679.4
cytochrome b5 reductase 4
chr5_-_79950775 0.37 ENST00000439211.2
dihydrofolate reductase
chr1_-_221915418 0.37 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr4_+_178230985 0.37 ENST00000264596.3
nei endonuclease VIII-like 3 (E. coli)
chr5_+_43120985 0.37 ENST00000515326.1
zinc finger protein 131
chr13_+_114238997 0.37 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.2 3.6 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.8 2.5 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.8 3.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.7 2.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.7 2.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 3.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.5 1.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 6.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 7.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 5.0 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 3.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 0.9 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.9 GO:0006272 leading strand elongation(GO:0006272)
0.2 4.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 1.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 2.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 3.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.5 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 1.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.4 GO:0042148 strand invasion(GO:0042148)
0.1 1.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 0.4 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 6.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.2 GO:0015695 organic cation transport(GO:0015695)
0.1 1.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 1.4 GO:0045141 meiotic telomere clustering(GO:0045141)
0.1 0.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.1 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.1 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.6 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 5.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 1.6 GO:0061157 mRNA destabilization(GO:0061157)
0.0 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.2 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 3.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:1903845 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0031055 chromatin remodeling at centromere(GO:0031055)
0.0 0.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.2 GO:0051301 cell division(GO:0051301)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035189 Rb-E2F complex(GO:0035189)
0.7 2.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.4 1.7 GO:0000811 GINS complex(GO:0000811)
0.4 7.7 GO:0042555 MCM complex(GO:0042555)
0.2 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 1.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 3.6 GO:0000800 lateral element(GO:0000800)
0.2 3.2 GO:0071439 clathrin complex(GO:0071439)
0.1 5.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.6 GO:0001740 Barr body(GO:0001740)
0.1 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 5.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.4 GO:0000796 condensin complex(GO:0000796)
0.1 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.5 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 0.6 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 1.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 5.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 5.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 2.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.7 5.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.6 4.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.4 GO:0036033 mediator complex binding(GO:0036033)
0.3 7.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.4 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 3.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.2 3.3 GO:0000150 recombinase activity(GO:0000150)
0.2 1.1 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 2.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 1.6 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.7 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.7 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.4 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.8 GO:0016594 glycine binding(GO:0016594)
0.1 2.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.4 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 4.8 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 5.1 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 16.1 PID ATR PATHWAY ATR signaling pathway
0.1 3.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.5 8.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 2.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 5.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.6 REACTOME KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)