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Illumina Body Map 2: averaged replicates

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Results for E2F2_E2F5

Z-value: 1.90

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F2
ENSG00000133740.6 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg19_v2_chr1_-_23857698_238577330.691.3e-05Click!
E2F5hg19_v2_chr8_+_86089619_860896530.412.0e-02Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_36235529 4.40 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
CLSPN
claspin
chr1_-_23857698 4.16 ENST00000361729.2
E2F2
E2F transcription factor 2
chr2_-_27498186 2.96 ENST00000447008.2
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr20_-_32274179 2.91 ENST00000343380.5
E2F1
E2F transcription factor 1
chr2_-_235405679 2.70 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr16_-_3030407 2.29 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr16_-_3030283 2.06 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr2_-_27498208 2.05 ENST00000424577.1
ENST00000426569.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr15_+_32907691 1.94 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
ARHGAP11A
Rho GTPase activating protein 11A
chr2_+_174219548 1.88 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7
cell division cycle associated 7
chr2_+_27498331 1.88 ENST00000402462.1
ENST00000404433.1
ENST00000406962.1
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr22_+_35796108 1.82 ENST00000382011.5
ENST00000416905.1
MCM5
minichromosome maintenance complex component 5
chr3_+_10857885 1.82 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr12_-_45270077 1.81 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr3_+_44803209 1.77 ENST00000326047.4
KIF15
kinesin family member 15
chr20_-_35724388 1.74 ENST00000344359.3
ENST00000373664.3
RBL1
retinoblastoma-like 1 (p107)
chr10_+_96305535 1.72 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr12_-_45270151 1.67 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr13_+_32889605 1.64 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
BRCA2
breast cancer 2, early onset
chr1_-_120612240 1.61 ENST00000256646.2
NOTCH2
notch 2
chr2_+_27498289 1.60 ENST00000296097.3
ENST00000420191.1
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr3_+_127317705 1.56 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr12_-_45269430 1.56 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr20_+_2082494 1.55 ENST00000246032.3
STK35
serine/threonine kinase 35
chr22_+_35796056 1.53 ENST00000216122.4
MCM5
minichromosome maintenance complex component 5
chr1_-_26232522 1.48 ENST00000399728.1
STMN1
stathmin 1
chr12_-_45269769 1.47 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr3_+_127317066 1.43 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr10_+_96305610 1.39 ENST00000371332.4
ENST00000239026.6
HELLS
helicase, lymphoid-specific
chr2_+_10263298 1.37 ENST00000474701.1
RRM2
ribonucleotide reductase M2
chr22_+_42095497 1.36 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr1_-_26232951 1.34 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr6_+_27775899 1.33 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr1_-_36235559 1.28 ENST00000251195.5
CLSPN
claspin
chr7_+_50344289 1.26 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr12_-_12849073 1.24 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chr6_+_135502501 1.24 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr7_-_148581251 1.22 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr8_+_94929110 1.21 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_154265784 1.20 ENST00000240488.3
MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr15_-_64673630 1.18 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr8_+_94929077 1.16 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr10_+_112327425 1.15 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr3_-_48229846 1.13 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr2_+_17935119 1.12 ENST00000317402.7
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr10_+_13203543 1.10 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chr4_+_71859156 1.09 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr20_+_25388293 1.09 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr15_+_40987327 1.09 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chr2_+_47168630 1.08 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr6_+_27114861 1.07 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr15_-_64673665 1.06 ENST00000300035.4
KIAA0101
KIAA0101
chr2_-_219433014 1.05 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr1_+_25598989 1.04 ENST00000454452.2
RHD
Rh blood group, D antigen
chr12_-_45269251 1.04 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr17_+_29158962 1.04 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr8_+_94929168 1.03 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_17935383 1.03 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr12_-_77459306 1.01 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr1_+_25599018 1.00 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr7_+_120590803 0.99 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr5_-_79950371 0.99 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chr1_+_151043070 0.99 ENST00000368918.3
ENST00000368917.1
GABPB2
GA binding protein transcription factor, beta subunit 2
chr1_+_212208919 0.98 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_219433281 0.98 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr8_+_94929273 0.96 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_-_79177673 0.94 ENST00000377208.5
POU4F1
POU class 4 homeobox 1
chr7_-_148581360 0.91 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr2_+_219433588 0.91 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_10679644 0.90 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr6_-_27782548 0.89 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr4_-_130014609 0.88 ENST00000511426.1
SCLT1
sodium channel and clathrin linker 1
chr15_+_40987661 0.88 ENST00000526763.1
RAD51
RAD51 recombinase
chr10_-_58120996 0.85 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZWINT
ZW10 interacting kinetochore protein
chr4_-_130014705 0.84 ENST00000503401.1
SCLT1
sodium channel and clathrin linker 1
chr3_+_10068095 0.84 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr3_+_44803322 0.84 ENST00000481166.2
KIF15
kinesin family member 15
chr8_-_67525524 0.84 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr8_-_67525473 0.83 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_26233423 0.81 ENST00000357865.2
STMN1
stathmin 1
chr3_-_53080047 0.79 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr9_-_104500862 0.79 ENST00000361820.3
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr1_+_25598872 0.78 ENST00000328664.4
RHD
Rh blood group, D antigen
chr13_-_41768654 0.77 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr4_-_130014729 0.76 ENST00000281142.5
ENST00000434680.1
SCLT1
sodium channel and clathrin linker 1
chr19_-_10679697 0.76 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr22_-_38966172 0.76 ENST00000216024.2
DMC1
DNA meiotic recombinase 1
chr5_-_176738883 0.76 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr12_-_58131931 0.75 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_135502408 0.75 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr9_-_123639445 0.75 ENST00000312189.6
PHF19
PHD finger protein 19
chr15_-_70388943 0.74 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr2_+_10262857 0.73 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr1_+_36038971 0.73 ENST00000373235.3
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr11_+_125495862 0.73 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
CHEK1
checkpoint kinase 1
chr4_-_174256276 0.72 ENST00000296503.5
HMGB2
high mobility group box 2
chr16_-_89007491 0.72 ENST00000327483.5
ENST00000564416.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr20_+_5931497 0.71 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chrX_+_123095890 0.71 ENST00000435215.1
STAG2
stromal antigen 2
chr6_-_27806117 0.71 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr4_-_130014532 0.70 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1
sodium channel and clathrin linker 1
chr16_+_3019552 0.70 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr2_+_47168313 0.70 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr1_-_23670752 0.70 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chrX_-_131623982 0.69 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr9_+_82186682 0.69 ENST00000376552.2
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_122238464 0.68 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr1_+_66458072 0.68 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_-_10305752 0.68 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr19_+_50094866 0.66 ENST00000418929.2
PRR12
proline rich 12
chrX_-_131623874 0.66 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chrX_-_135849484 0.65 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_+_4918342 0.64 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr2_-_17935027 0.63 ENST00000446852.1
SMC6
structural maintenance of chromosomes 6
chr6_+_31707725 0.62 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5
mutS homolog 5
chr1_+_145209092 0.62 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr22_-_38966123 0.62 ENST00000439567.1
DMC1
DNA meiotic recombinase 1
chr2_-_96700664 0.62 ENST00000359548.4
ENST00000377137.3
ENST00000439254.1
ENST00000453542.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr3_-_133380731 0.62 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr1_-_32801825 0.62 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr8_-_98290087 0.62 ENST00000322128.3
TSPYL5
TSPY-like 5
chr16_-_85722530 0.61 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr5_+_93954358 0.61 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr10_+_62538089 0.61 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr7_+_120591170 0.60 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chrX_+_75648046 0.59 ENST00000361470.2
MAGEE1
melanoma antigen family E, 1
chr19_-_6502590 0.59 ENST00000264071.2
TUBB4A
tubulin, beta 4A class IVa
chrX_+_123095860 0.58 ENST00000428941.1
STAG2
stromal antigen 2
chr18_+_2655849 0.58 ENST00000261598.8
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr1_-_91487013 0.58 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr15_-_40401062 0.58 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr15_+_44719394 0.57 ENST00000260327.4
ENST00000396780.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_-_105517021 0.56 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr3_-_14220068 0.56 ENST00000449060.2
ENST00000511155.1
XPC
xeroderma pigmentosum, complementation group C
chr6_+_135502466 0.56 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr22_+_35653445 0.56 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr12_-_133263893 0.56 ENST00000535270.1
ENST00000320574.5
POLE
polymerase (DNA directed), epsilon, catalytic subunit
chr1_-_23670813 0.55 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr9_-_123639304 0.55 ENST00000436309.1
PHF19
PHD finger protein 19
chr19_-_10305302 0.55 ENST00000592054.1
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr1_-_228645556 0.55 ENST00000366695.2
HIST3H2A
histone cluster 3, H2a
chr5_+_93954039 0.54 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chrX_+_131157322 0.54 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr5_+_43121698 0.54 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131
zinc finger protein 131
chrX_+_131157290 0.54 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr11_+_64808368 0.54 ENST00000531072.1
ENST00000398846.1
SAC3D1
SAC3 domain containing 1
chr14_-_50154921 0.54 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr11_-_64739358 0.51 ENST00000301896.5
ENST00000530444.1
C11orf85
chromosome 11 open reading frame 85
chr5_+_36152091 0.51 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr2_-_17935059 0.50 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
SMC6
structural maintenance of chromosomes 6
chr9_+_106856831 0.50 ENST00000303219.8
ENST00000374787.3
SMC2
structural maintenance of chromosomes 2
chr8_+_48873479 0.50 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr7_-_158497431 0.50 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
NCAPG2
non-SMC condensin II complex, subunit G2
chr11_-_64739542 0.49 ENST00000536065.1
C11orf85
chromosome 11 open reading frame 85
chr3_+_16926441 0.49 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr15_+_64752927 0.49 ENST00000416172.1
ZNF609
zinc finger protein 609
chr1_-_47779762 0.48 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL
SCL/TAL1 interrupting locus
chr1_-_149812765 0.48 ENST00000369158.1
HIST2H3C
histone cluster 2, H3c
chr15_+_44719790 0.48 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_53925063 0.48 ENST00000371445.3
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr9_-_35079911 0.47 ENST00000448890.1
FANCG
Fanconi anemia, complementation group G
chr8_+_48873453 0.47 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr7_-_100026280 0.47 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr22_+_42394780 0.47 ENST00000328823.9
WBP2NL
WBP2 N-terminal like
chrX_+_101906294 0.46 ENST00000361600.5
ENST00000415986.1
ENST00000444152.1
ENST00000537097.1
GPRASP1
G protein-coupled receptor associated sorting protein 1
chrX_+_100353153 0.45 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr19_-_6502341 0.45 ENST00000598006.1
ENST00000601152.1
TUBB4A
tubulin, beta 4A class IVa
chr1_-_202679535 0.45 ENST00000367268.4
SYT2
synaptotagmin II
chr9_-_123639600 0.45 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_-_100598444 0.45 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr19_-_10444188 0.44 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr9_-_113800705 0.44 ENST00000441240.1
LPAR1
lysophosphatidic acid receptor 1
chr4_-_175750364 0.44 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr5_+_43121607 0.44 ENST00000509156.1
ENST00000508259.1
ENST00000306938.4
ENST00000399534.1
ZNF131
zinc finger protein 131
chr22_-_29137771 0.43 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr17_-_26879567 0.43 ENST00000581945.1
ENST00000444148.1
ENST00000301032.4
ENST00000335765.4
UNC119
unc-119 homolog (C. elegans)
chrX_+_70798261 0.43 ENST00000373696.3
ACRC
acidic repeat containing
chr6_+_26045603 0.43 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr2_+_61108771 0.43 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_-_122758994 0.42 ENST00000306467.5
ENST00000515110.1
CEP120
centrosomal protein 120kDa
chr5_+_36152179 0.42 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr17_-_57184170 0.42 ENST00000393065.2
TRIM37
tripartite motif containing 37
chr17_-_42580738 0.42 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr9_-_99180597 0.42 ENST00000375256.4
ZNF367
zinc finger protein 367
chr10_+_102672712 0.41 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr12_-_122238913 0.41 ENST00000537157.1
AC084018.1
AC084018.1
chr15_+_44719996 0.40 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_133861790 0.40 ENST00000395003.1
PHF15
jade family PHD finger 2
chr11_-_118966167 0.40 ENST00000530167.1
H2AFX
H2A histone family, member X
chr9_+_106856541 0.39 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
SMC2
structural maintenance of chromosomes 2
chr16_-_30102547 0.39 ENST00000279386.2
TBX6
T-box 6
chr10_+_62538248 0.39 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr1_-_91487770 0.39 ENST00000337393.5
ZNF644
zinc finger protein 644
chr5_+_36876833 0.38 ENST00000282516.8
ENST00000448238.2
NIPBL
Nipped-B homolog (Drosophila)
chr6_+_84569359 0.38 ENST00000369681.5
ENST00000369679.4
CYB5R4
cytochrome b5 reductase 4
chr5_-_79950775 0.37 ENST00000439211.2
DHFR
dihydrofolate reductase
chr1_-_221915418 0.37 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr4_+_178230985 0.37 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr5_+_43120985 0.37 ENST00000515326.1
ZNF131
zinc finger protein 131
chr13_+_114238997 0.37 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.2 3.6 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.8 2.5 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.8 3.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.7 2.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.7 2.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 3.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.5 1.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 6.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 7.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 5.0 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 3.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 0.9 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.9 GO:0006272 leading strand elongation(GO:0006272)
0.2 4.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 1.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 2.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 3.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.5 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 1.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.4 GO:0042148 strand invasion(GO:0042148)
0.1 1.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 0.4 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 6.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.2 GO:0015695 organic cation transport(GO:0015695)
0.1 1.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 1.4 GO:0045141 meiotic telomere clustering(GO:0045141)
0.1 0.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.1 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.1 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.6 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 5.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 1.6 GO:0061157 mRNA destabilization(GO:0061157)
0.0 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.2 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 3.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:1903845 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0031055 chromatin remodeling at centromere(GO:0031055)
0.0 0.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.2 GO:0051301 cell division(GO:0051301)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035189 Rb-E2F complex(GO:0035189)
0.7 2.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.4 1.7 GO:0000811 GINS complex(GO:0000811)
0.4 7.7 GO:0042555 MCM complex(GO:0042555)
0.2 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 1.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 3.6 GO:0000800 lateral element(GO:0000800)
0.2 3.2 GO:0071439 clathrin complex(GO:0071439)
0.1 5.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.6 GO:0001740 Barr body(GO:0001740)
0.1 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 5.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.4 GO:0000796 condensin complex(GO:0000796)
0.1 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.5 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 0.6 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 1.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 5.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 5.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 2.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.7 5.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.6 4.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.4 GO:0036033 mediator complex binding(GO:0036033)
0.3 7.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.4 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 3.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.2 3.3 GO:0000150 recombinase activity(GO:0000150)
0.2 1.1 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 2.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 1.6 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.7 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.7 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.4 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.8 GO:0016594 glycine binding(GO:0016594)
0.1 2.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.4 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 4.8 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 5.1 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 16.1 PID ATR PATHWAY ATR signaling pathway
0.1 3.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.5 8.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 2.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 5.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.6 REACTOME KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)