Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for EBF1
Z-value: 2.69
Motif logo
Transcription factors associated with EBF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EBF1 | hg19_v2_chr5_-_158526756_158526797 | 0.28 | 1.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_+_23229960 Show fit | 7.68 |
ENST00000526893.1
ENST00000532223.2 ENST00000531372.1 |
immunoglobulin lambda-like polypeptide 5 |
|
| chr22_+_23101182 Show fit | 3.82 |
ENST00000390312.2
|
immunoglobulin lambda variable 2-14 |
|
| chr22_+_22697537 Show fit | 3.42 |
ENST00000427632.2
|
immunoglobulin lambda variable 9-49 |
|
| chr2_+_89890533 Show fit | 3.37 |
ENST00000429992.2
|
immunoglobulin kappa variable 2D-40 |
|
| chr6_-_31550192 Show fit | 3.35 |
ENST00000429299.2
ENST00000446745.2 |
lymphotoxin beta (TNF superfamily, member 3) |
|
| chr22_-_23922410 Show fit | 3.24 |
ENST00000249053.3
|
immunoglobulin lambda-like polypeptide 1 |
|
| chr22_+_23154239 Show fit | 3.24 |
ENST00000390315.2
|
immunoglobulin lambda variable 3-10 |
|
| chr5_-_138725594 Show fit | 3.23 |
ENST00000302125.8
|
marginal zone B and B1 cell-specific protein |
|
| chr22_+_23241661 Show fit | 3.14 |
ENST00000390322.2
|
immunoglobulin lambda joining 2 |
|
| chr2_-_89327228 Show fit | 3.14 |
ENST00000483158.1
|
immunoglobulin kappa variable 3-11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of EBF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 34.8 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.3 | 31.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 28.9 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 11.4 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.1 | 6.8 | GO:0042100 | B cell proliferation(GO:0042100) |
| 1.0 | 6.1 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.2 | 5.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 5.2 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 4.5 | GO:0031294 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.4 | 4.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 32.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 16.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 10.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 9.8 | GO:0098793 | presynapse(GO:0098793) |
| 0.2 | 7.8 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.2 | 7.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.2 | 6.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 5.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.2 | 5.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.7 | 5.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 63.9 | GO:0003823 | antigen binding(GO:0003823) |
| 0.6 | 36.6 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 6.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 5.9 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 5.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 5.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.3 | 4.5 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 4.3 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 4.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.9 | 3.8 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 17.0 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 11.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 8.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 7.6 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 6.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 6.0 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 5.0 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 3.9 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 3.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 6.3 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 5.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 4.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 4.5 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 4.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 4.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 4.3 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 4.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 3.7 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |