Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for ELF3_EHF
Z-value: 2.74
Motif logo
Transcription factors associated with ELF3_EHF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EHF | hg19_v2_chr11_+_34645791_34645836 | 0.65 | 6.5e-05 | Click! |
| ELF3 | hg19_v2_chr1_+_201979743_201979772 | 0.56 | 9.6e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ELF3_EHF
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 13.4 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.1 | 9.5 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.4 | 9.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.5 | 8.6 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 1.6 | 8.0 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.3 | 8.0 | GO:0051639 | actin filament network formation(GO:0051639) |
| 1.0 | 7.8 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.5 | 7.7 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 7.4 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.1 | 6.2 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 19.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 13.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 12.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 12.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 11.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 9.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 8.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 8.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 7.7 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 6.2 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 18.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.3 | 10.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.7 | 9.9 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.2 | 9.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 8.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 1.6 | 7.8 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.0 | 7.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 7.3 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 6.8 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.1 | 6.5 | GO:0097110 | scaffold protein binding(GO:0097110) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 9.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 9.0 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 7.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 7.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 4.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 3.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.3 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 3.3 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 2.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 16.7 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.3 | 15.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.3 | 12.1 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.2 | 8.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 6.5 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 6.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 4.8 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 4.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 4.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 4.3 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |