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Illumina Body Map 2: averaged replicates

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Results for EOMES

Z-value: 1.27

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Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27764190_27764208-0.327.3e-02Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_139613269 3.03 ENST00000358430.3
taxilin beta
chr16_+_30064444 2.17 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
aldolase A, fructose-bisphosphate
chr16_+_30064411 1.84 ENST00000338110.5
aldolase A, fructose-bisphosphate
chrY_+_15016725 1.57 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr10_-_101190202 1.48 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr3_-_42744130 1.42 ENST00000417472.1
ENST00000442469.1
hedgehog acyltransferase-like
chr10_-_13342051 1.35 ENST00000479604.1
phytanoyl-CoA 2-hydroxylase
chrY_+_15016013 1.30 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_-_184943610 1.25 ENST00000367511.3
family with sequence similarity 129, member A
chr10_-_13342097 1.20 ENST00000263038.4
phytanoyl-CoA 2-hydroxylase
chr12_-_122879969 1.19 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr8_+_11561660 1.18 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA binding protein 4
chr11_+_1860832 1.15 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr8_-_121825088 1.15 ENST00000520717.1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr3_+_50649302 1.13 ENST00000446044.1
mitogen-activated protein kinase-activated protein kinase 3
chr10_+_135340859 1.10 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_+_1940925 1.07 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr8_+_49984894 1.07 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
chromosome 8 open reading frame 22
chr1_+_87170577 1.07 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr1_+_160121356 1.04 ENST00000368081.4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr15_+_36871983 1.04 ENST00000437989.2
ENST00000569302.1
chromosome 15 open reading frame 41
chr15_+_63413990 1.03 ENST00000261893.4
lactamase, beta
chr17_-_27949911 1.02 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
coronin 6
chr11_+_1860682 1.02 ENST00000381906.1
troponin I type 2 (skeletal, fast)
chr1_-_167906277 1.01 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr15_+_36871806 1.01 ENST00000566621.1
ENST00000564586.1
chromosome 15 open reading frame 41
chr5_-_37839782 0.97 ENST00000326524.2
ENST00000515058.1
glial cell derived neurotrophic factor
chr1_+_167906056 0.96 ENST00000367840.3
DDB1 and CUL4 associated factor 6
chr7_-_87104963 0.94 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr7_+_136553824 0.93 ENST00000320658.5
ENST00000453373.1
ENST00000397608.3
ENST00000402486.3
ENST00000401861.1
cholinergic receptor, muscarinic 2
chr9_+_96026230 0.92 ENST00000448251.1
WNK lysine deficient protein kinase 2
chr10_+_6779326 0.92 ENST00000417112.1
RP11-554I8.2
chr1_-_146644122 0.91 ENST00000254101.3
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr2_-_101767715 0.90 ENST00000376840.4
ENST00000409318.1
TBC1 domain family, member 8 (with GRAM domain)
chr3_-_52868931 0.90 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr1_-_203144941 0.89 ENST00000255416.4
myosin binding protein H
chr1_+_196912902 0.88 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr11_-_3663502 0.87 ENST00000359918.4
ADP-ribosyltransferase 5
chr15_-_56285742 0.87 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr22_+_47070490 0.85 ENST00000408031.1
GRAM domain containing 4
chr1_-_146644036 0.84 ENST00000425272.2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr1_+_228395755 0.84 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_+_35532612 0.83 ENST00000600390.1
ENST00000597419.1
hepsin
chr3_+_52811596 0.82 ENST00000542827.1
ENST00000273283.2
inter-alpha-trypsin inhibitor heavy chain 1
chr8_-_145050890 0.81 ENST00000436759.2
plectin
chr7_+_136553370 0.80 ENST00000445907.2
cholinergic receptor, muscarinic 2
chr10_-_103454876 0.77 ENST00000331272.7
F-box and WD repeat domain containing 4
chr22_+_40742512 0.76 ENST00000454266.2
ENST00000342312.6
adenylosuccinate lyase
chr3_-_52869205 0.75 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr5_+_75699149 0.75 ENST00000379730.3
IQ motif containing GTPase activating protein 2
chr17_-_39942322 0.74 ENST00000449889.1
ENST00000465293.1
junction plakoglobin
chr12_+_71833756 0.73 ENST00000536515.1
ENST00000540815.2
leucine-rich repeat containing G protein-coupled receptor 5
chr10_-_94333784 0.72 ENST00000265986.6
insulin-degrading enzyme
chr8_+_96037205 0.71 ENST00000396124.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_-_66056596 0.70 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chrX_-_71933888 0.70 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
phosphorylase kinase, alpha 1 (muscle)
chr17_-_41856305 0.69 ENST00000397937.2
ENST00000226004.3
dual specificity phosphatase 3
chr22_+_40742497 0.68 ENST00000216194.7
adenylosuccinate lyase
chr17_-_79917645 0.68 ENST00000477214.1
notum pectinacetylesterase homolog (Drosophila)
chr4_-_80994619 0.68 ENST00000404191.1
anthrax toxin receptor 2
chr4_-_114682224 0.67 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
calcium/calmodulin-dependent protein kinase II delta
chr6_+_34204642 0.67 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr7_-_43909090 0.67 ENST00000317534.5
mitochondrial ribosomal protein S24
chr7_+_16685756 0.67 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr11_+_64808675 0.67 ENST00000529996.1
SAC3 domain containing 1
chr17_+_67498295 0.66 ENST00000589295.1
mitogen-activated protein kinase kinase 6
chr10_+_1120312 0.66 ENST00000436154.1
WD repeat domain 37
chr1_+_193028717 0.66 ENST00000415442.2
ENST00000506303.1
TROVE domain family, member 2
chr12_+_95611569 0.64 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr11_+_86667117 0.63 ENST00000531827.1
RP11-736K20.6
chr1_-_167906020 0.63 ENST00000458574.1
mitochondrial pyruvate carrier 2
chr1_-_151119087 0.63 ENST00000341697.3
ENST00000368914.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr4_-_80994471 0.63 ENST00000295465.4
anthrax toxin receptor 2
chr1_-_25747283 0.63 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
Rh blood group, CcEe antigens
chr10_+_95653687 0.62 ENST00000371408.3
ENST00000427197.1
solute carrier family 35, member G1
chr1_+_230203010 0.61 ENST00000541865.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr16_-_87367879 0.61 ENST00000568879.1
RP11-178L8.4
chr16_-_66959429 0.61 ENST00000420652.1
ENST00000299759.6
Ras-related associated with diabetes
chr19_+_7599597 0.61 ENST00000414982.3
ENST00000450331.3
patatin-like phospholipase domain containing 6
chr1_-_36851475 0.60 ENST00000373129.3
serine/threonine kinase 40
chr12_-_33049690 0.59 ENST00000070846.6
ENST00000340811.4
plakophilin 2
chr5_-_137610254 0.59 ENST00000378362.3
GDNF family receptor alpha 3
chr19_-_49496557 0.58 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
glycogen synthase 1 (muscle)
chr19_+_33865218 0.58 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_+_43148059 0.58 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr4_-_4291761 0.58 ENST00000513174.1
Ly1 antibody reactive
chr11_-_57103327 0.58 ENST00000529002.1
ENST00000278412.2
structure specific recognition protein 1
chr8_+_96037255 0.58 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr15_+_67835005 0.58 ENST00000178640.5
mitogen-activated protein kinase kinase 5
chr7_-_96339132 0.58 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr17_+_67498538 0.58 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr1_+_150459873 0.58 ENST00000438568.2
ENST00000369054.2
ENST00000369064.3
ENST00000606933.1
threonyl-tRNA synthetase 2, mitochondrial (putative)
chrM_+_8527 0.58 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr15_+_63414017 0.57 ENST00000413507.2
lactamase, beta
chr18_+_43753500 0.57 ENST00000587591.1
ENST00000588730.1
chromosome 18 open reading frame 25
chr8_-_145018905 0.57 ENST00000398774.2
plectin
chr4_-_114682364 0.57 ENST00000511664.1
calcium/calmodulin-dependent protein kinase II delta
chr11_-_67188642 0.55 ENST00000546202.1
ENST00000542876.1
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_-_85666688 0.55 ENST00000341460.5
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr19_+_34856078 0.55 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
glucose-6-phosphate isomerase
chr10_-_61900762 0.55 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chrM_+_9207 0.54 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr13_+_28195988 0.54 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr19_+_7599128 0.52 ENST00000545201.2
patatin-like phospholipase domain containing 6
chr22_+_45680822 0.52 ENST00000216211.4
ENST00000396082.2
uroplakin 3A
chr15_+_67835517 0.52 ENST00000395476.2
mitogen-activated protein kinase kinase 5
chr18_-_74839891 0.52 ENST00000581878.1
myelin basic protein
chr3_-_180707306 0.52 ENST00000479269.1
DnaJ (Hsp40) homolog, subfamily C, member 19
chr8_-_103668114 0.51 ENST00000285407.6
Kruppel-like factor 10
chr9_-_140444814 0.51 ENST00000277531.4
patatin-like phospholipase domain containing 7
chr19_+_7598890 0.51 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
patatin-like phospholipase domain containing 6
chr4_+_87857538 0.51 ENST00000511442.1
AF4/FMR2 family, member 1
chr20_+_43029911 0.51 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
hepatocyte nuclear factor 4, alpha
chr4_-_114682326 0.50 ENST00000505990.1
calcium/calmodulin-dependent protein kinase II delta
chr5_+_172261228 0.50 ENST00000393784.3
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr1_+_64669294 0.50 ENST00000371077.5
ubiquitin-conjugating enzyme E2U (putative)
chr20_+_1099233 0.50 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr16_+_4896659 0.50 ENST00000592120.1
ubinuclein 1
chr2_+_105654441 0.50 ENST00000258455.3
mitochondrial ribosomal protein S9
chr2_-_54197915 0.49 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr13_+_28194873 0.49 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr6_+_160769399 0.49 ENST00000392145.1
solute carrier family 22 (organic cation transporter), member 3
chr2_-_152118352 0.49 ENST00000331426.5
RNA binding motif protein 43
chr4_-_80994210 0.49 ENST00000403729.2
anthrax toxin receptor 2
chr1_+_222791417 0.49 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
melanoma inhibitory activity family, member 3
chr2_-_230135937 0.48 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
phosphotyrosine interaction domain containing 1
chr4_-_4291748 0.48 ENST00000452476.1
Ly1 antibody reactive
chrM_+_8366 0.48 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr2_-_10830093 0.48 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
nucleolar protein 10
chr14_+_57857262 0.48 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr17_+_48351785 0.48 ENST00000507382.1
transmembrane protein 92
chr7_+_129710350 0.48 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr17_-_17723746 0.48 ENST00000577897.1
sterol regulatory element binding transcription factor 1
chr17_-_39942940 0.48 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
junction plakoglobin
chr5_-_133968459 0.47 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1 homolog B (S. cerevisiae)
chr20_-_42939782 0.47 ENST00000396825.3
fat storage-inducing transmembrane protein 2
chrX_-_63615297 0.47 ENST00000374852.3
ENST00000453546.1
myotubularin related protein 8
chr11_+_64073699 0.46 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr3_-_182698381 0.46 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr21_+_33671264 0.45 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr19_-_48867171 0.45 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
transmembrane protein 143
chr11_+_111896090 0.45 ENST00000393051.1
dihydrolipoamide S-acetyltransferase
chr5_+_443280 0.45 ENST00000508022.1
exocyst complex component 3
chr14_-_99947121 0.45 ENST00000329331.3
ENST00000436070.2
SET domain containing 3
chr12_+_131438443 0.45 ENST00000261654.5
G protein-coupled receptor 133
chr10_+_85899196 0.45 ENST00000372134.3
growth hormone inducible transmembrane protein
chr17_+_46018872 0.45 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
pyridoxamine 5'-phosphate oxidase
chr5_+_172261356 0.45 ENST00000523291.1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr17_+_72427477 0.44 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr17_+_9066252 0.44 ENST00000436734.1
netrin 1
chr12_+_95611536 0.44 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chr7_+_99699179 0.44 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr15_-_102029873 0.44 ENST00000348070.1
ENST00000358417.3
ENST00000344273.2
proprotein convertase subtilisin/kexin type 6
chr11_+_111896320 0.44 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr5_-_14871866 0.44 ENST00000284268.6
ANKH inorganic pyrophosphate transport regulator
chr6_-_82957433 0.43 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_+_172261311 0.43 ENST00000520326.1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr22_-_42486747 0.43 ENST00000602404.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr17_-_1588101 0.43 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
pre-mRNA processing factor 8
chr11_-_66139570 0.43 ENST00000311161.7
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr1_+_101003687 0.43 ENST00000315033.4
G protein-coupled receptor 88
chr8_-_135708787 0.42 ENST00000520356.1
ENST00000520727.1
ENST00000520214.1
ENST00000518191.1
ENST00000429442.2
zinc finger and AT hook domain containing
chr9_-_140444867 0.42 ENST00000406427.1
patatin-like phospholipase domain containing 7
chr15_+_43622843 0.42 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
adenosine deaminase-like
chr5_-_137610300 0.42 ENST00000274721.3
GDNF family receptor alpha 3
chr19_+_50270219 0.41 ENST00000354293.5
ENST00000359032.5
adaptor-related protein complex 2, alpha 1 subunit
chr14_+_104029278 0.41 ENST00000472726.2
ENST00000409074.2
ENST00000440963.1
ENST00000556253.2
ENST00000247618.4
Kinesin light chain 1
apoptogenic 1, mitochondrial
chr1_+_150229554 0.41 ENST00000369111.4
carbonic anhydrase XIV
chr6_+_3259122 0.41 ENST00000438998.2
ENST00000380305.4
proteasome (prosome, macropain) assembly chaperone 4
chr19_-_48867291 0.41 ENST00000435956.3
transmembrane protein 143
chr17_-_42188598 0.41 ENST00000591714.1
histone deacetylase 5
chr1_-_228135599 0.41 ENST00000272164.5
wingless-type MMTV integration site family, member 9A
chr9_+_2017420 0.41 ENST00000439732.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_+_3827459 0.41 ENST00000416600.2
ENST00000428216.2
mitochondrial antiviral signaling protein
chr16_+_31120429 0.41 ENST00000484226.2
branched chain ketoacid dehydrogenase kinase
chr11_+_93861993 0.40 ENST00000227638.3
ENST00000436171.2
pannexin 1
chr19_-_14228541 0.40 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr7_+_99699280 0.40 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr16_+_29817841 0.40 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr1_+_162531294 0.40 ENST00000367926.4
ENST00000271469.3
UDP-N-acteylglucosamine pyrophosphorylase 1
chr17_+_19552036 0.40 ENST00000581518.1
ENST00000395575.2
ENST00000584332.2
ENST00000339618.4
ENST00000579855.1
aldehyde dehydrogenase 3 family, member A2
chr13_-_52026730 0.39 ENST00000420668.2
integrator complex subunit 6
chr6_-_163148700 0.39 ENST00000366894.1
ENST00000338468.3
parkin RBR E3 ubiquitin protein ligase
chr6_-_163148780 0.39 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr5_+_443268 0.39 ENST00000512944.1
exocyst complex component 3
chr6_-_35888858 0.39 ENST00000507909.1
SRSF protein kinase 1
chr1_-_33283754 0.39 ENST00000373477.4
tyrosyl-tRNA synthetase
chr19_-_40791302 0.39 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr14_-_70263979 0.39 ENST00000216540.4
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr1_+_3689325 0.38 ENST00000444870.2
ENST00000452264.1
small integral membrane protein 1 (Vel blood group)
chr19_-_16008880 0.38 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr8_-_124408652 0.38 ENST00000287394.5
ATPase family, AAA domain containing 2
chr5_+_61708582 0.38 ENST00000325324.6
importin 11
chr3_-_43147431 0.38 ENST00000441964.1
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr11_+_112097069 0.38 ENST00000280362.3
ENST00000525803.1
6-pyruvoyltetrahydropterin synthase
chr16_+_3162557 0.38 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
zinc finger protein 205
chr12_+_95611516 0.37 ENST00000436874.1
vezatin, adherens junctions transmembrane protein
chr7_-_96339167 0.37 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
split hand/foot malformation (ectrodactyly) type 1
chr19_+_8478154 0.37 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr19_+_34856141 0.37 ENST00000586425.1
glucose-6-phosphate isomerase

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.5 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.4 1.6 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4 1.4 GO:0060262 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.3 0.9 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.3 1.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.3 1.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 1.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.3 1.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.7 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 1.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 3.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.1 GO:0010193 response to ozone(GO:0010193)
0.2 0.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 1.8 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.7 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.6 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.7 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.4 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.8 GO:0036309 protein localization to M-band(GO:0036309)
0.1 1.0 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 0.8 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.7 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 1.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.4 GO:0098736 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.5 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.5 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.4 GO:0032902 nerve growth factor production(GO:0032902)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.7 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.3 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.7 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.5 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0035572 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.4 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.7 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.6 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 1.1 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 1.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.7 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.6 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 3.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0060157 urinary bladder development(GO:0060157)
0.0 1.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 3.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.8 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 1.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.6 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.4 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.9 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 2.2 GO:1901998 toxin transport(GO:1901998)
0.0 3.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0006294 nucleotide-excision repair, DNA duplex unwinding(GO:0000717) nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 1.0 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 1.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0043970 histone H3-K9 acetylation(GO:0043970) regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 3.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.7 GO:0048806 genitalia development(GO:0048806)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.2 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 3.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 1.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 5.7 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.3 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 1.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.1 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 3.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.5 1.5 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 3.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.3 0.9 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.3 1.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.7 GO:0031626 beta-endorphin binding(GO:0031626)
0.2 0.7 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 1.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.6 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 0.9 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 0.7 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.2 0.9 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 0.6 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 2.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.6 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 2.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 1.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 3.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.9 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 2.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 3.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0000217 DNA secondary structure binding(GO:0000217) four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 1.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 4.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 6.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.3 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation