Project

Illumina Body Map 2: averaged replicates

Navigation
Downloads

Results for ESR1

Z-value: 2.50

Motif logo

Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152130240_1521302740.309.3e-02Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_23029188 6.46 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr22_+_22676808 4.41 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr22_+_23089870 3.80 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr22_+_23046750 3.46 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr14_-_106209368 3.41 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22681656 3.27 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr22_+_23165153 3.24 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr22_+_23154239 3.07 ENST00000390315.2
immunoglobulin lambda variable 3-10
chr17_-_3595042 2.98 ENST00000552723.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_-_89513402 2.97 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr21_-_47352477 2.94 ENST00000593412.1
Uncharacterized protein
chr15_-_20170354 2.92 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr8_+_11351876 2.79 ENST00000529894.1
B lymphoid tyrosine kinase
chr14_-_107035208 2.79 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr22_+_23247030 2.69 ENST00000390324.2
immunoglobulin lambda joining 3
chr22_-_24096630 2.69 ENST00000248948.3
pre-B lymphocyte 3
chr8_+_11351494 2.69 ENST00000259089.4
B lymphoid tyrosine kinase
chr14_-_106453155 2.66 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr2_+_98330009 2.66 ENST00000264972.5
zeta-chain (TCR) associated protein kinase 70kDa
chr22_+_22723969 2.65 ENST00000390295.2
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr22_+_23010756 2.63 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr22_+_22550113 2.58 ENST00000390285.3
immunoglobulin lambda variable 6-57
chr9_+_130478345 2.52 ENST00000373289.3
ENST00000393748.4
tetratricopeptide repeat domain 16
chr14_-_106642049 2.52 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr22_+_23248512 2.42 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr14_+_106384295 2.42 ENST00000449410.1
ENST00000429431.1
KIAA0125
chr19_+_42381173 2.34 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr9_-_139652678 2.33 ENST00000371688.3
lipocalin 8
chr2_-_89310012 2.32 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr14_-_91884150 2.32 ENST00000553403.1
coiled-coil domain containing 88C
chr14_-_106330824 2.23 ENST00000463911.1
immunoglobulin heavy joining 3
chr22_-_24096562 2.19 ENST00000398465.3
pre-B lymphocyte 3
chr1_+_161677034 2.07 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
Fc receptor-like A
chr7_-_142139783 2.03 ENST00000390374.3
T cell receptor beta variable 7-6
chr14_-_107078851 2.01 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr17_-_73840774 2.01 ENST00000207549.4
unc-13 homolog D (C. elegans)
chr5_+_110559784 1.98 ENST00000282356.4
calcium/calmodulin-dependent protein kinase IV
chr2_-_89247338 1.92 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr7_-_142181009 1.92 ENST00000390368.2
T cell receptor beta variable 6-5
chr22_+_23222886 1.91 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr11_+_67171391 1.88 ENST00000312390.5
TBC1 domain family, member 10C
chr14_-_91720224 1.86 ENST00000238699.3
ENST00000531499.2
G protein-coupled receptor 68
chr22_+_23077065 1.84 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr16_+_89686991 1.84 ENST00000393092.3
dipeptidase 1 (renal)
chr20_+_61584398 1.82 ENST00000411611.1
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr5_+_110559603 1.81 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr22_+_22735135 1.80 ENST00000390297.2
immunoglobulin lambda variable 1-44
chr1_+_1266654 1.79 ENST00000339381.5
taste receptor, type 1, member 3
chr11_-_111320706 1.79 ENST00000531398.1
POU class 2 associating factor 1
chr11_+_67171548 1.79 ENST00000542590.1
TBC1 domain family, member 10C
chr19_+_49838653 1.78 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr11_+_67171358 1.77 ENST00000526387.1
TBC1 domain family, member 10C
chr22_+_23241661 1.77 ENST00000390322.2
immunoglobulin lambda joining 2
chr22_+_23213658 1.77 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr19_-_7764281 1.75 ENST00000360067.4
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr14_+_106355918 1.73 ENST00000414005.1
AL122127.25
chr22_+_22930626 1.71 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr17_+_15635561 1.71 ENST00000584301.1
ENST00000580596.1
ENST00000464963.1
ENST00000437605.2
ENST00000579428.1
TBC1 domain family, member 26
chr22_-_23922448 1.69 ENST00000438703.1
ENST00000330377.2
immunoglobulin lambda-like polypeptide 1
chr14_-_91884115 1.69 ENST00000389857.6
coiled-coil domain containing 88C
chr22_+_23243156 1.68 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr5_-_66492562 1.65 ENST00000256447.4
CD180 molecule
chr22_+_22385332 1.65 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr2_+_231090471 1.65 ENST00000373645.3
SP140 nuclear body protein
chr8_-_101661887 1.64 ENST00000311812.2
sorting nexin 31
chr2_+_231090433 1.64 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140 nuclear body protein
chr14_-_106725723 1.63 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr7_+_97840739 1.63 ENST00000609256.1
basic helix-loop-helix family, member a15
chr22_+_22936998 1.63 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr2_-_89292422 1.57 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_+_22236722 1.55 ENST00000390428.3
T cell receptor alpha variable 6
chr7_-_142176790 1.55 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr3_-_46506358 1.55 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr15_+_81225699 1.54 ENST00000560027.1
KIAA1199
chr17_+_38673270 1.53 ENST00000578280.1
RP5-1028K7.2
chr14_-_106054659 1.53 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_-_23922410 1.52 ENST00000249053.3
immunoglobulin lambda-like polypeptide 1
chr14_-_106066376 1.52 ENST00000412518.1
ENST00000428654.1
ENST00000427543.1
ENST00000420153.1
ENST00000577108.1
ENST00000576077.1
AL928742.12
immunoglobulin heavy constant epsilon
chr16_+_69985083 1.51 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr16_+_1291240 1.49 ENST00000561736.1
tryptase alpha/beta 1
chr7_-_142247606 1.48 ENST00000390361.3
T cell receptor beta variable 7-3
chr20_+_49411523 1.46 ENST00000371608.2
breast carcinoma amplified sequence 4
chr1_+_26348259 1.42 ENST00000374280.3
exostosin-like glycosyltransferase 1
chr8_+_96281045 1.42 ENST00000521905.1
KB-1047C11.2
chr6_-_2903514 1.41 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr6_+_35265586 1.38 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr1_+_207070775 1.33 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
interleukin 24
chr5_+_110559312 1.31 ENST00000508074.1
calcium/calmodulin-dependent protein kinase IV
chr19_-_10445399 1.31 ENST00000592945.1
intercellular adhesion molecule 3
chr9_-_139927462 1.29 ENST00000314412.6
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr20_+_61584026 1.29 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr1_-_111970353 1.28 ENST00000369732.3
oviductal glycoprotein 1, 120kDa
chr1_+_32827759 1.26 ENST00000373534.3
testis-specific serine kinase 3
chr2_+_228029281 1.25 ENST00000396578.3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr19_+_544034 1.25 ENST00000592501.1
ENST00000264553.3
granzyme M (lymphocyte met-ase 1)
chr19_+_45690646 1.25 ENST00000591569.1
Uncharacterized protein
chr3_+_47021168 1.24 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr22_+_22453093 1.24 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr5_-_131347306 1.24 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
acyl-CoA synthetase long-chain family member 6
chr5_-_131347583 1.24 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr3_-_13461807 1.23 ENST00000254508.5
nucleoporin 210kDa
chr1_-_32827682 1.20 ENST00000432622.1
family with sequence similarity 229, member A
chr16_+_70207686 1.19 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
C-type lectin domain family 18, member C
chr5_-_156593273 1.18 ENST00000302938.4
family with sequence similarity 71, member B
chr19_+_36024310 1.17 ENST00000222286.4
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_-_131347501 1.15 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr17_-_34207295 1.14 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chrY_+_9236030 1.12 ENST00000457222.2
ENST00000440483.1
ENST00000424594.1
ENST00000427871.2
ENST00000423647.2
testis specific protein, Y-linked 3
testis specific protein, Y-linked 1
chr16_+_69984810 1.12 ENST00000393701.2
ENST00000568461.1
C-type lectin domain family 18, member A
chr11_+_64107663 1.11 ENST00000356786.5
coiled-coil domain containing 88B
chr16_+_57576584 1.11 ENST00000340339.4
G protein-coupled receptor 114
chr22_+_37318624 1.10 ENST00000421539.1
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr13_-_46964177 1.10 ENST00000389908.3
KIAA0226-like
chr14_+_100485712 1.09 ENST00000544450.2
Enah/Vasp-like
chr19_-_39104556 1.09 ENST00000423454.2
mitogen-activated protein kinase kinase kinase kinase 1
chr16_+_50730910 1.08 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr1_+_901847 1.08 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
pleckstrin homology domain containing, family N member 1
chr4_-_111536534 1.08 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2
chr6_-_41006928 1.08 ENST00000244565.3
unc-5 homolog C (C. elegans)-like
chr16_-_74455290 1.08 ENST00000339953.5
C-type lectin domain family 18, member B
chr16_+_85936295 1.05 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
interferon regulatory factor 8
chr6_+_36973406 1.05 ENST00000274963.8
FYVE, RhoGEF and PH domain containing 2
chr9_+_136399929 1.04 ENST00000393060.1
ADAMTS-like 2
chr14_-_106331447 1.04 ENST00000390564.2
immunoglobulin heavy joining 2
chr1_+_9711781 1.03 ENST00000536656.1
ENST00000377346.4
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr1_+_118148556 1.03 ENST00000369448.3
family with sequence similarity 46, member C
chr16_+_30485267 1.01 ENST00000569725.1
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr20_+_42295745 1.01 ENST00000396863.4
ENST00000217026.4
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr12_-_30907822 0.99 ENST00000540436.1
caprin family member 2
chr14_+_22670455 0.97 ENST00000390460.1
T cell receptor alpha variable 26-2
chr2_+_177015950 0.97 ENST00000306324.3
homeobox D4
chr16_+_1306093 0.97 ENST00000211076.3
tryptase delta 1
chr12_-_14996355 0.97 ENST00000228936.4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr22_+_39853258 0.96 ENST00000341184.6
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr12_+_54378923 0.93 ENST00000303460.4
homeobox C10
chr10_+_99349450 0.93 ENST00000370640.3
chromosome 10 open reading frame 62
chr19_-_13213662 0.92 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr3_-_183273477 0.92 ENST00000341319.3
kelch-like family member 6
chr16_-_88772670 0.91 ENST00000562544.1
ring finger protein 166
chr9_+_126118449 0.90 ENST00000359999.3
ENST00000373631.3
crumbs homolog 2 (Drosophila)
chr8_+_103563792 0.89 ENST00000285402.3
outer dense fiber of sperm tails 1
chr15_+_90792760 0.88 ENST00000339615.5
ENST00000438251.1
tubulin tyrosine ligase-like family, member 13
chr19_-_42498369 0.87 ENST00000302102.5
ENST00000545399.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrY_+_9195406 0.87 ENST00000287721.9
ENST00000383005.2
ENST00000383000.1
ENST00000330628.9
ENST00000537415.1
testis specific protein, Y-linked 8
chr12_+_123259063 0.86 ENST00000392441.4
ENST00000539171.1
coiled-coil domain containing 62
chr11_-_117699413 0.86 ENST00000528014.1
FXYD domain containing ion transport regulator 2
chr11_+_1891380 0.86 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr17_+_29718642 0.85 ENST00000325874.8
RAB11 family interacting protein 4 (class II)
chr17_-_46688334 0.85 ENST00000239165.7
homeobox B7
chr19_-_42498231 0.84 ENST00000602133.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr9_+_139874683 0.84 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr19_-_13213954 0.83 ENST00000590974.1
lymphoblastic leukemia derived sequence 1
chr14_-_106471723 0.82 ENST00000390595.2
immunoglobulin heavy variable 1-3
chr6_+_99282570 0.81 ENST00000328345.5
POU class 3 homeobox 2
chr22_-_37505449 0.80 ENST00000406725.1
transmembrane protease, serine 6
chr22_-_19137796 0.80 ENST00000086933.2
goosecoid homeobox 2
chr6_-_109776901 0.80 ENST00000431946.1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr11_+_62186498 0.80 ENST00000278282.2
secretoglobin, family 1A, member 1 (uteroglobin)
chr9_-_134151915 0.79 ENST00000372271.3
family with sequence similarity 78, member A
chr12_-_13256571 0.79 ENST00000545401.1
ENST00000432710.2
ENST00000351606.6
germ cell associated 1
chr11_+_67056755 0.78 ENST00000511455.2
ENST00000308440.6
ankyrin repeat domain 13 family, member D
chr15_+_94774767 0.78 ENST00000543482.1
multiple C2 domains, transmembrane 2
chrX_+_55101495 0.77 ENST00000374974.3
ENST00000374971.1
P antigen family, member 2B
chr19_-_1513188 0.76 ENST00000330475.4
ADAMTS-like 5
chr18_+_47901408 0.75 ENST00000398452.2
ENST00000417656.2
ENST00000488454.1
ENST00000494518.1
spindle and kinetochore associated complex subunit 1
chr19_-_14586125 0.75 ENST00000292513.3
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr9_+_135037334 0.74 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
netrin G2
chr11_+_102188272 0.74 ENST00000532808.1
baculoviral IAP repeat containing 3
chr12_-_49365501 0.73 ENST00000403957.1
ENST00000301061.4
wingless-type MMTV integration site family, member 10B
chr19_-_7812446 0.72 ENST00000394173.4
ENST00000301357.8
CD209 molecule
chr1_+_203734296 0.72 ENST00000442561.2
ENST00000367217.5
lymphocyte transmembrane adaptor 1
chr11_-_9482010 0.71 ENST00000596206.1
LOC644656 protein; Uncharacterized protein
chr1_+_206972215 0.71 ENST00000340758.2
interleukin 19
chr16_-_88772761 0.70 ENST00000567844.1
ENST00000312838.4
ring finger protein 166
chrY_+_9175073 0.70 ENST00000426950.2
ENST00000383008.1
testis specific protein, Y-linked 4
chrY_+_9365489 0.69 ENST00000428845.2
ENST00000444056.1
ENST00000429039.1
testis specific protein, Y-linked 10
chr6_-_109777128 0.69 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr5_+_171212876 0.69 ENST00000330910.3
ENST00000523047.1
small integral membrane protein 23
chr10_-_44274273 0.69 ENST00000419406.1
RP11-272J7.4
chr4_+_110481348 0.69 ENST00000394650.4
coiled-coil domain containing 109B
chr17_-_18547731 0.69 ENST00000575220.1
ENST00000405044.1
ENST00000572213.1
ENST00000573652.1
TBC1 domain family, member 28
chr20_+_43538756 0.69 ENST00000537323.1
ENST00000217073.2
poly(A) binding protein, cytoplasmic 1-like
chr6_+_31462658 0.69 ENST00000538442.1
MHC class I polypeptide-related sequence B
chr11_+_102188224 0.69 ENST00000263464.3
baculoviral IAP repeat containing 3
chr15_+_81489213 0.69 ENST00000559383.1
ENST00000394660.2
interleukin 16
chrY_+_9324922 0.69 ENST00000440215.2
ENST00000446779.2
testis specific protein, Y-linked 6, pseudogene
chrX_-_104465358 0.68 ENST00000372578.3
ENST00000372575.1
ENST00000413579.1
testis expressed 13A
chr15_-_73076030 0.68 ENST00000311669.8
ADP-dependent glucokinase
chr12_+_54378849 0.67 ENST00000515593.1
homeobox C10
chr14_+_27342334 0.66 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
chr20_+_42086525 0.66 ENST00000244020.3
serine/arginine-rich splicing factor 6
chr6_-_74161977 0.66 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chrX_+_147062844 0.65 ENST00000370467.3
fragile X mental retardation 1 neighbor
chr6_-_91006461 0.65 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr22_+_38035623 0.65 ENST00000336738.5
ENST00000442465.2
SH3-domain binding protein 1
chr19_-_35719609 0.65 ENST00000324675.3
family with sequence similarity 187, member B
chr19_-_7812397 0.63 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209 molecule
chr16_+_29471210 0.63 ENST00000360423.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_+_59522284 0.62 ENST00000449812.2
RP11-145M4.3
chr7_+_76139833 0.62 ENST00000257632.5
uroplakin 3B

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.6 1.8 GO:0016999 antibiotic metabolic process(GO:0016999)
0.5 5.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.5 1.5 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.5 2.0 GO:0002432 granuloma formation(GO:0002432)
0.5 1.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 1.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 2.7 GO:0043366 beta selection(GO:0043366)
0.4 1.3 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 2.5 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 3.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.4 1.5 GO:0019417 sulfur oxidation(GO:0019417)
0.3 2.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 1.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3 1.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 49.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.9 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.3 1.4 GO:0046968 peptide antigen transport(GO:0046968)
0.2 1.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 1.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.2 1.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.2 1.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 0.9 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 1.0 GO:0060374 positive regulation of neutrophil apoptotic process(GO:0033031) mast cell differentiation(GO:0060374)
0.2 36.8 GO:0002377 immunoglobulin production(GO:0002377)
0.2 0.8 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 0.5 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 1.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.1 1.0 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.6 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.4 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 1.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.8 GO:0010193 response to ozone(GO:0010193)
0.1 0.9 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.2 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.6 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.8 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 1.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 5.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 2.2 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 1.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.7 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.5 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 0.3 GO:0071879 UDP-glucose catabolic process(GO:0006258) response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 3.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.7 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 1.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.5 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.7 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 3.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:0044785 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.9 GO:0002467 germinal center formation(GO:0002467)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.1 GO:0031648 protein destabilization(GO:0031648)
0.1 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.3 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.1 0.2 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.0 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.7 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.2 GO:0030220 platelet formation(GO:0030220)
0.0 0.5 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0097106 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106)
0.0 0.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.6 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 1.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.1 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 2.7 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 4.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 1.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.9 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.7 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.9 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.2 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 1.0 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.6 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 1.0 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.0 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.0 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.4 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.0 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.0 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.7 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.4 20.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.1 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.3 2.3 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 0.3 GO:0031982 vesicle(GO:0031982)
0.3 0.9 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 1.0 GO:0031523 Myb complex(GO:0031523)
0.2 1.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 2.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 0.8 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 1.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 3.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 4.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.7 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 0.2 GO:0000502 proteasome complex(GO:0000502)
0.1 1.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 12.1 GO:0072562 blood microparticle(GO:0072562)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 1.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 9.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.8 GO:0044216 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 36.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.3 22.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 1.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3 59.0 GO:0003823 antigen binding(GO:0003823)
0.2 3.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.1 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 0.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 5.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.5 GO:0004103 choline kinase activity(GO:0004103)
0.2 2.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 1.8 GO:0019863 IgE binding(GO:0019863)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 1.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 1.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 2.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.6 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 5.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 3.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 1.3 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 8.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.8 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 1.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0016015 morphogen activity(GO:0016015)
0.0 12.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.1 7.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 5.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 2.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 ST GA13 PATHWAY G alpha 13 Pathway
0.0 7.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 9.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 3.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.1 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling