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Illumina Body Map 2: averaged replicates
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Results for ESRRB_ESRRG
Z-value: 4.56
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Transcription factors associated with ESRRB_ESRRG
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ESRRB
|
ENSG00000119715.10 | estrogen related receptor beta |
|
ESRRG
|
ENSG00000196482.12 | estrogen related receptor gamma |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ESRRG | hg19_v2_chr1_-_216896780_216896800 | 0.81 | 1.9e-08 | Click! |
| ESRRB | hg19_v2_chr14_+_76776957_76777061 | 0.59 | 3.9e-04 | Click! |
Activity profile of ESRRB_ESRRG motif
Sorted Z-values of ESRRB_ESRRG motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_42743006 | 16.87 |
ENST00000310417.5
|
HHATL
|
hedgehog acyltransferase-like |
| chr20_-_62130474 | 16.78 |
ENST00000217182.3
|
EEF1A2
|
eukaryotic translation elongation factor 1 alpha 2 |
| chr5_+_80529104 | 15.93 |
ENST00000254035.4
ENST00000511719.1 ENST00000437669.1 ENST00000424301.2 ENST00000505060.1 |
CKMT2
|
creatine kinase, mitochondrial 2 (sarcomeric) |
| chr3_-_42744130 | 12.72 |
ENST00000417472.1
ENST00000442469.1 |
HHATL
|
hedgehog acyltransferase-like |
| chr11_-_790060 | 12.60 |
ENST00000330106.4
|
CEND1
|
cell cycle exit and neuronal differentiation 1 |
| chr19_-_55669093 | 10.77 |
ENST00000344887.5
|
TNNI3
|
troponin I type 3 (cardiac) |
| chr16_+_58535372 | 10.32 |
ENST00000566656.1
ENST00000566618.1 |
NDRG4
|
NDRG family member 4 |
| chr1_+_169077133 | 10.29 |
ENST00000494797.1
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr22_+_31518938 | 9.96 |
ENST00000412985.1
ENST00000331075.5 ENST00000412277.2 ENST00000420017.1 ENST00000400294.2 ENST00000405300.1 ENST00000404390.3 |
INPP5J
|
inositol polyphosphate-5-phosphatase J |
| chr2_+_220491973 | 9.49 |
ENST00000358055.3
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr1_+_169077172 | 9.46 |
ENST00000499679.3
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr1_+_202995611 | 9.30 |
ENST00000367240.2
|
PPFIA4
|
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| chr14_-_21492251 | 9.20 |
ENST00000554398.1
|
NDRG2
|
NDRG family member 2 |
| chr10_-_50970382 | 9.11 |
ENST00000419399.1
ENST00000432695.1 |
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr1_+_236849754 | 8.66 |
ENST00000542672.1
ENST00000366578.4 |
ACTN2
|
actinin, alpha 2 |
| chr3_+_121311966 | 8.55 |
ENST00000338040.4
|
FBXO40
|
F-box protein 40 |
| chr3_-_42744312 | 8.51 |
ENST00000416756.1
ENST00000441594.1 |
HHATL
|
hedgehog acyltransferase-like |
| chr1_+_207226574 | 8.24 |
ENST00000367080.3
ENST00000367079.2 |
PFKFB2
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| chr1_+_153600869 | 8.09 |
ENST00000292169.1
ENST00000368696.3 ENST00000436839.1 |
S100A1
|
S100 calcium binding protein A1 |
| chr3_-_38691119 | 8.04 |
ENST00000333535.4
ENST00000413689.1 ENST00000443581.1 ENST00000425664.1 ENST00000451551.2 |
SCN5A
|
sodium channel, voltage-gated, type V, alpha subunit |
| chr15_+_43985725 | 7.96 |
ENST00000413453.2
|
CKMT1A
|
creatine kinase, mitochondrial 1A |
| chr15_+_43885252 | 7.72 |
ENST00000453782.1
ENST00000300283.6 ENST00000437924.1 ENST00000450086.2 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr15_+_43886057 | 7.59 |
ENST00000441322.1
ENST00000413657.2 ENST00000453733.1 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr9_+_95997205 | 7.58 |
ENST00000411624.1
|
WNK2
|
WNK lysine deficient protein kinase 2 |
| chr10_-_50970322 | 7.56 |
ENST00000374103.4
|
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr3_-_42744270 | 7.50 |
ENST00000457462.1
|
HHATL
|
hedgehog acyltransferase-like |
| chr5_+_149569520 | 7.49 |
ENST00000230671.2
ENST00000524041.1 |
SLC6A7
|
solute carrier family 6 (neurotransmitter transporter), member 7 |
| chr15_+_43985084 | 7.44 |
ENST00000434505.1
ENST00000411750.1 |
CKMT1A
|
creatine kinase, mitochondrial 1A |
| chr14_-_21491477 | 7.38 |
ENST00000298684.5
ENST00000557169.1 ENST00000553563.1 |
NDRG2
|
NDRG family member 2 |
| chr14_-_21492113 | 7.15 |
ENST00000554094.1
|
NDRG2
|
NDRG family member 2 |
| chr2_+_220492116 | 7.12 |
ENST00000373760.2
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr6_-_97345689 | 6.96 |
ENST00000316149.7
|
NDUFAF4
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| chr12_-_111358372 | 6.59 |
ENST00000548438.1
ENST00000228841.8 |
MYL2
|
myosin, light chain 2, regulatory, cardiac, slow |
| chr19_-_45826125 | 6.35 |
ENST00000221476.3
|
CKM
|
creatine kinase, muscle |
| chr19_+_589893 | 6.33 |
ENST00000251287.2
|
HCN2
|
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 |
| chr4_-_186661365 | 6.13 |
ENST00000452351.1
|
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr10_-_101190202 | 6.01 |
ENST00000543866.1
ENST00000370508.5 |
GOT1
|
glutamic-oxaloacetic transaminase 1, soluble |
| chr16_-_66952779 | 5.86 |
ENST00000570262.1
ENST00000394055.3 ENST00000299752.4 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr4_-_21699380 | 5.83 |
ENST00000382148.3
|
KCNIP4
|
Kv channel interacting protein 4 |
| chr1_-_144995074 | 5.71 |
ENST00000534536.1
|
PDE4DIP
|
phosphodiesterase 4D interacting protein |
| chr2_+_220492287 | 5.47 |
ENST00000273063.6
ENST00000373762.3 |
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr18_-_12377001 | 5.47 |
ENST00000590811.1
|
AFG3L2
|
AFG3-like AAA ATPase 2 |
| chr2_+_220492373 | 5.37 |
ENST00000317151.3
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr5_-_160975130 | 5.32 |
ENST00000274547.2
ENST00000520240.1 ENST00000517901.1 ENST00000353437.6 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| chr18_-_56296182 | 5.27 |
ENST00000361673.3
|
ALPK2
|
alpha-kinase 2 |
| chr18_-_44336998 | 5.22 |
ENST00000315087.7
|
ST8SIA5
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| chr11_+_86667117 | 5.21 |
ENST00000531827.1
|
RP11-736K20.6
|
RP11-736K20.6 |
| chr20_+_58179582 | 5.10 |
ENST00000371015.1
ENST00000395639.4 |
PHACTR3
|
phosphatase and actin regulator 3 |
| chr7_+_123241908 | 5.09 |
ENST00000434204.1
ENST00000437535.1 ENST00000451215.1 |
ASB15
|
ankyrin repeat and SOCS box containing 15 |
| chr17_-_27503770 | 5.05 |
ENST00000533112.1
|
MYO18A
|
myosin XVIIIA |
| chr1_-_144995002 | 4.99 |
ENST00000369356.4
|
PDE4DIP
|
phosphodiesterase 4D interacting protein |
| chr16_-_66952742 | 4.99 |
ENST00000565235.2
ENST00000568632.1 ENST00000565796.1 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr14_-_103987679 | 4.96 |
ENST00000553610.1
|
CKB
|
creatine kinase, brain |
| chr19_-_4517613 | 4.88 |
ENST00000301286.3
|
PLIN4
|
perilipin 4 |
| chr1_+_169075554 | 4.84 |
ENST00000367815.4
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr19_-_51192661 | 4.78 |
ENST00000391813.1
|
SHANK1
|
SH3 and multiple ankyrin repeat domains 1 |
| chr1_-_217250231 | 4.77 |
ENST00000493748.1
ENST00000463665.1 |
ESRRG
|
estrogen-related receptor gamma |
| chr22_-_24110063 | 4.75 |
ENST00000520222.1
ENST00000401675.3 |
CHCHD10
|
coiled-coil-helix-coiled-coil-helix domain containing 10 |
| chr17_-_42988004 | 4.75 |
ENST00000586125.1
ENST00000591880.1 |
GFAP
|
glial fibrillary acidic protein |
| chr15_-_83621435 | 4.73 |
ENST00000450735.2
ENST00000426485.1 ENST00000399166.2 ENST00000304231.8 |
HOMER2
|
homer homolog 2 (Drosophila) |
| chr18_-_43678241 | 4.71 |
ENST00000593152.2
ENST00000589252.1 ENST00000590665.1 ENST00000398752.6 |
ATP5A1
|
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle |
| chr11_-_111794446 | 4.70 |
ENST00000527950.1
|
CRYAB
|
crystallin, alpha B |
| chr1_-_201342364 | 4.54 |
ENST00000236918.7
ENST00000367317.4 ENST00000367315.2 ENST00000360372.4 |
TNNT2
|
troponin T type 2 (cardiac) |
| chr12_+_119616447 | 4.43 |
ENST00000281938.2
|
HSPB8
|
heat shock 22kDa protein 8 |
| chr1_-_145075847 | 4.41 |
ENST00000530740.1
ENST00000369359.4 |
PDE4DIP
|
phosphodiesterase 4D interacting protein |
| chr12_-_57039739 | 4.39 |
ENST00000552959.1
ENST00000551020.1 ENST00000553007.2 ENST00000552919.1 ENST00000552104.1 ENST00000262030.3 |
ATP5B
|
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
| chr1_-_917466 | 4.36 |
ENST00000341290.2
|
C1orf170
|
chromosome 1 open reading frame 170 |
| chr13_+_22245522 | 4.34 |
ENST00000382353.5
|
FGF9
|
fibroblast growth factor 9 |
| chr11_+_66059339 | 4.26 |
ENST00000327259.4
|
TMEM151A
|
transmembrane protein 151A |
| chr16_+_21964662 | 4.26 |
ENST00000561553.1
ENST00000565331.1 |
UQCRC2
|
ubiquinol-cytochrome c reductase core protein II |
| chr3_-_42845922 | 4.25 |
ENST00000452906.2
|
HIGD1A
|
HIG1 hypoxia inducible domain family, member 1A |
| chr16_+_6069586 | 4.24 |
ENST00000547372.1
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr1_-_241683001 | 4.19 |
ENST00000366560.3
|
FH
|
fumarate hydratase |
| chr18_-_12377283 | 4.16 |
ENST00000269143.3
|
AFG3L2
|
AFG3-like AAA ATPase 2 |
| chr2_-_176046391 | 4.15 |
ENST00000392541.3
ENST00000409194.1 |
ATP5G3
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) |
| chr3_+_186435065 | 4.13 |
ENST00000287611.2
ENST00000265023.4 |
KNG1
|
kininogen 1 |
| chr8_+_145149930 | 4.10 |
ENST00000318911.4
|
CYC1
|
cytochrome c-1 |
| chr20_+_58152524 | 4.09 |
ENST00000359926.3
|
PHACTR3
|
phosphatase and actin regulator 3 |
| chr9_-_130637244 | 4.09 |
ENST00000373156.1
|
AK1
|
adenylate kinase 1 |
| chr7_-_113559104 | 4.09 |
ENST00000284601.3
|
PPP1R3A
|
protein phosphatase 1, regulatory subunit 3A |
| chr22_-_29711645 | 4.08 |
ENST00000401450.3
|
RASL10A
|
RAS-like, family 10, member A |
| chr18_-_44336754 | 4.08 |
ENST00000538168.1
ENST00000536490.1 |
ST8SIA5
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| chr1_-_145076186 | 4.07 |
ENST00000369348.3
|
PDE4DIP
|
phosphodiesterase 4D interacting protein |
| chr7_+_56032270 | 4.07 |
ENST00000322090.3
ENST00000446778.1 |
GBAS
|
glioblastoma amplified sequence |
| chr3_+_186435137 | 4.04 |
ENST00000447445.1
|
KNG1
|
kininogen 1 |
| chr22_-_29711704 | 4.01 |
ENST00000216101.6
|
RASL10A
|
RAS-like, family 10, member A |
| chr17_-_29624343 | 3.94 |
ENST00000247271.4
|
OMG
|
oligodendrocyte myelin glycoprotein |
| chr7_-_138458781 | 3.90 |
ENST00000393054.1
|
ATP6V0A4
|
ATPase, H+ transporting, lysosomal V0 subunit a4 |
| chr19_-_36643329 | 3.89 |
ENST00000589154.1
|
COX7A1
|
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
| chr7_+_35756186 | 3.82 |
ENST00000430518.1
|
AC018647.3
|
AC018647.3 |
| chr3_-_50605077 | 3.81 |
ENST00000426034.1
ENST00000441239.1 |
C3orf18
|
chromosome 3 open reading frame 18 |
| chr16_+_6069072 | 3.79 |
ENST00000547605.1
ENST00000550418.1 ENST00000553186.1 |
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr5_+_126984710 | 3.78 |
ENST00000379445.3
|
CTXN3
|
cortexin 3 |
| chr5_+_218356 | 3.76 |
ENST00000264932.6
ENST00000504309.1 ENST00000510361.1 |
SDHA
|
succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| chr11_+_34938119 | 3.71 |
ENST00000227868.4
ENST00000430469.2 ENST00000533262.1 |
PDHX
|
pyruvate dehydrogenase complex, component X |
| chr8_+_136469684 | 3.69 |
ENST00000355849.5
|
KHDRBS3
|
KH domain containing, RNA binding, signal transduction associated 3 |
| chr8_+_86376081 | 3.66 |
ENST00000285379.5
|
CA2
|
carbonic anhydrase II |
| chr15_+_78441663 | 3.62 |
ENST00000299518.2
ENST00000558554.1 ENST00000557826.1 ENST00000561279.1 ENST00000559186.1 ENST00000560770.1 ENST00000559881.1 ENST00000559205.1 ENST00000441490.2 |
IDH3A
|
isocitrate dehydrogenase 3 (NAD+) alpha |
| chr11_-_132813566 | 3.62 |
ENST00000331898.7
|
OPCML
|
opioid binding protein/cell adhesion molecule-like |
| chr7_-_44180673 | 3.61 |
ENST00000457314.1
ENST00000447951.1 ENST00000431007.1 |
MYL7
|
myosin, light chain 7, regulatory |
| chr14_-_35183755 | 3.61 |
ENST00000555765.1
|
CFL2
|
cofilin 2 (muscle) |
| chr17_-_1553346 | 3.61 |
ENST00000301336.6
|
RILP
|
Rab interacting lysosomal protein |
| chr3_+_179322481 | 3.60 |
ENST00000259037.3
|
NDUFB5
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
| chr6_+_53948221 | 3.57 |
ENST00000460844.2
|
MLIP
|
muscular LMNA-interacting protein |
| chr16_+_57481349 | 3.57 |
ENST00000262507.6
ENST00000565964.1 |
COQ9
|
coenzyme Q9 |
| chr3_+_179322573 | 3.56 |
ENST00000493866.1
ENST00000472629.1 ENST00000482604.1 |
NDUFB5
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
| chr16_+_6069664 | 3.55 |
ENST00000422070.4
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr8_-_100905850 | 3.55 |
ENST00000520271.1
ENST00000522940.1 ENST00000523016.1 ENST00000517682.2 ENST00000297564.2 |
COX6C
|
cytochrome c oxidase subunit VIc |
| chr3_-_108672609 | 3.54 |
ENST00000393963.3
ENST00000471108.1 |
GUCA1C
|
guanylate cyclase activator 1C |
| chr11_-_47470703 | 3.52 |
ENST00000298854.2
|
RAPSN
|
receptor-associated protein of the synapse |
| chr11_-_34379546 | 3.52 |
ENST00000435224.2
|
ABTB2
|
ankyrin repeat and BTB (POZ) domain containing 2 |
| chr16_-_19896832 | 3.50 |
ENST00000537135.1
ENST00000564449.1 |
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chr19_+_16771936 | 3.48 |
ENST00000187762.2
ENST00000599479.1 |
TMEM38A
|
transmembrane protein 38A |
| chr18_-_48351743 | 3.45 |
ENST00000588444.1
ENST00000256425.2 ENST00000428869.2 |
MRO
|
maestro |
| chr3_-_42845951 | 3.43 |
ENST00000418900.2
ENST00000430190.1 |
HIGD1A
|
HIG1 hypoxia inducible domain family, member 1A |
| chr21_-_27107344 | 3.40 |
ENST00000457143.2
|
ATP5J
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
| chr11_-_1783633 | 3.38 |
ENST00000367196.3
|
CTSD
|
cathepsin D |
| chr7_-_44180884 | 3.37 |
ENST00000458240.1
ENST00000223364.3 |
MYL7
|
myosin, light chain 7, regulatory |
| chr10_+_81107271 | 3.37 |
ENST00000448165.1
|
PPIF
|
peptidylprolyl isomerase F |
| chr22_+_42372764 | 3.34 |
ENST00000396426.3
ENST00000406029.1 |
SEPT3
|
septin 3 |
| chr12_+_6644443 | 3.33 |
ENST00000396858.1
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase |
| chr5_+_113391696 | 3.33 |
ENST00000512927.1
|
RP11-371M22.1
|
RP11-371M22.1 |
| chr6_+_53948328 | 3.32 |
ENST00000370876.2
|
MLIP
|
muscular LMNA-interacting protein |
| chr8_+_125551338 | 3.29 |
ENST00000276689.3
ENST00000518008.1 ENST00000522532.1 ENST00000517367.1 |
NDUFB9
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa |
| chr21_-_27107198 | 3.29 |
ENST00000400094.1
|
ATP5J
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
| chr9_-_130889990 | 3.27 |
ENST00000449878.1
|
PTGES2
|
prostaglandin E synthase 2 |
| chr3_-_183735651 | 3.27 |
ENST00000427120.2
ENST00000392579.2 ENST00000382494.2 ENST00000446941.2 |
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| chr2_+_86426478 | 3.24 |
ENST00000254644.8
ENST00000605125.1 ENST00000337109.4 ENST00000409180.1 |
MRPL35
|
mitochondrial ribosomal protein L35 |
| chr2_-_74374995 | 3.22 |
ENST00000295326.4
|
BOLA3
|
bolA family member 3 |
| chr21_-_27107283 | 3.20 |
ENST00000284971.3
ENST00000400099.1 |
ATP5J
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
| chr17_+_37821593 | 3.19 |
ENST00000578283.1
|
TCAP
|
titin-cap |
| chr16_-_19897455 | 3.18 |
ENST00000568214.1
ENST00000569479.1 |
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chr8_-_110704014 | 3.17 |
ENST00000529190.1
ENST00000422135.1 ENST00000419099.1 |
SYBU
|
syntabulin (syntaxin-interacting) |
| chr14_-_35183886 | 3.17 |
ENST00000298159.6
|
CFL2
|
cofilin 2 (muscle) |
| chr7_-_92848858 | 3.16 |
ENST00000440868.1
|
HEPACAM2
|
HEPACAM family member 2 |
| chr9_+_133978190 | 3.16 |
ENST00000372312.3
|
AIF1L
|
allograft inflammatory factor 1-like |
| chr20_+_13765596 | 3.15 |
ENST00000378106.5
ENST00000463598.1 |
NDUFAF5
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| chr1_+_203096831 | 3.14 |
ENST00000337894.4
|
ADORA1
|
adenosine A1 receptor |
| chr8_-_100905363 | 3.12 |
ENST00000524245.1
|
COX6C
|
cytochrome c oxidase subunit VIc |
| chr7_-_92848878 | 3.12 |
ENST00000341723.4
|
HEPACAM2
|
HEPACAM family member 2 |
| chr16_+_58533951 | 3.07 |
ENST00000566192.1
ENST00000565088.1 ENST00000568640.1 ENST00000563978.1 ENST00000569923.1 ENST00000356752.4 ENST00000563799.1 ENST00000562999.1 ENST00000570248.1 ENST00000562731.1 ENST00000568424.1 |
NDRG4
|
NDRG family member 4 |
| chr4_+_30721968 | 3.06 |
ENST00000361762.2
|
PCDH7
|
protocadherin 7 |
| chr10_-_97200772 | 3.05 |
ENST00000371241.1
ENST00000354106.3 ENST00000371239.1 ENST00000361941.3 ENST00000277982.5 ENST00000371245.3 |
SORBS1
|
sorbin and SH3 domain containing 1 |
| chr10_+_81107216 | 3.03 |
ENST00000394579.3
ENST00000225174.3 |
PPIF
|
peptidylprolyl isomerase F |
| chr7_-_10979750 | 3.00 |
ENST00000339600.5
|
NDUFA4
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa |
| chr12_+_121163602 | 2.99 |
ENST00000411593.2
|
ACADS
|
acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| chr8_+_67405755 | 2.99 |
ENST00000521495.1
|
C8orf46
|
chromosome 8 open reading frame 46 |
| chr15_+_43809797 | 2.98 |
ENST00000399453.1
ENST00000300231.5 |
MAP1A
|
microtubule-associated protein 1A |
| chr10_+_60028818 | 2.97 |
ENST00000333926.5
|
CISD1
|
CDGSH iron sulfur domain 1 |
| chr2_+_172950227 | 2.96 |
ENST00000341900.6
|
DLX1
|
distal-less homeobox 1 |
| chr7_+_94536898 | 2.96 |
ENST00000433360.1
ENST00000340694.4 ENST00000424654.1 |
PPP1R9A
|
protein phosphatase 1, regulatory subunit 9A |
| chr3_-_108672742 | 2.93 |
ENST00000261047.3
|
GUCA1C
|
guanylate cyclase activator 1C |
| chr22_+_46546494 | 2.92 |
ENST00000396000.2
ENST00000262735.5 ENST00000420804.1 |
PPARA
|
peroxisome proliferator-activated receptor alpha |
| chr10_+_116853091 | 2.90 |
ENST00000526946.1
|
ATRNL1
|
attractin-like 1 |
| chr16_-_3767551 | 2.88 |
ENST00000246957.5
|
TRAP1
|
TNF receptor-associated protein 1 |
| chr8_+_67405794 | 2.87 |
ENST00000522977.1
ENST00000480005.1 |
C8orf46
|
chromosome 8 open reading frame 46 |
| chr15_+_63050785 | 2.86 |
ENST00000472902.1
|
TLN2
|
talin 2 |
| chr20_-_48099182 | 2.86 |
ENST00000371741.4
|
KCNB1
|
potassium voltage-gated channel, Shab-related subfamily, member 1 |
| chr1_-_151798546 | 2.85 |
ENST00000356728.6
|
RORC
|
RAR-related orphan receptor C |
| chr15_+_43885799 | 2.84 |
ENST00000449946.1
ENST00000417289.1 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr19_+_18726786 | 2.84 |
ENST00000594709.1
|
TMEM59L
|
transmembrane protein 59-like |
| chr9_-_32573130 | 2.83 |
ENST00000350021.2
ENST00000379847.3 |
NDUFB6
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| chrX_-_46187069 | 2.81 |
ENST00000446884.1
|
RP1-30G7.2
|
RP1-30G7.2 |
| chr4_+_44680429 | 2.80 |
ENST00000281543.5
|
GUF1
|
GUF1 GTPase homolog (S. cerevisiae) |
| chr9_-_35685452 | 2.78 |
ENST00000607559.1
|
TPM2
|
tropomyosin 2 (beta) |
| chr2_+_115822233 | 2.77 |
ENST00000393146.2
|
DPP10
|
dipeptidyl-peptidase 10 (non-functional) |
| chr2_-_106054952 | 2.77 |
ENST00000336660.5
ENST00000393352.3 ENST00000607522.1 |
FHL2
|
four and a half LIM domains 2 |
| chr7_+_35756092 | 2.75 |
ENST00000458087.3
|
AC018647.3
|
AC018647.3 |
| chr15_+_59730348 | 2.75 |
ENST00000288228.5
ENST00000559628.1 ENST00000557914.1 ENST00000560474.1 |
FAM81A
|
family with sequence similarity 81, member A |
| chr1_-_17380630 | 2.69 |
ENST00000375499.3
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| chr4_+_41614909 | 2.66 |
ENST00000509454.1
ENST00000396595.3 ENST00000381753.4 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chr8_-_100905925 | 2.66 |
ENST00000518171.1
|
COX6C
|
cytochrome c oxidase subunit VIc |
| chr14_-_21490958 | 2.65 |
ENST00000554104.1
|
NDRG2
|
NDRG family member 2 |
| chr1_-_31661000 | 2.65 |
ENST00000263693.1
ENST00000398657.2 ENST00000526106.1 |
NKAIN1
|
Na+/K+ transporting ATPase interacting 1 |
| chr17_-_2615031 | 2.65 |
ENST00000576885.1
ENST00000574426.2 |
CLUH
|
clustered mitochondria (cluA/CLU1) homolog |
| chr7_+_94536514 | 2.64 |
ENST00000413325.1
|
PPP1R9A
|
protein phosphatase 1, regulatory subunit 9A |
| chr15_-_77988485 | 2.64 |
ENST00000561030.1
|
LINGO1
|
leucine rich repeat and Ig domain containing 1 |
| chr17_+_34058639 | 2.62 |
ENST00000268864.3
|
RASL10B
|
RAS-like, family 10, member B |
| chr16_-_58768177 | 2.61 |
ENST00000434819.2
ENST00000245206.5 |
GOT2
|
glutamic-oxaloacetic transaminase 2, mitochondrial |
| chr16_+_56623433 | 2.58 |
ENST00000570176.1
|
MT3
|
metallothionein 3 |
| chr10_-_21186144 | 2.58 |
ENST00000377119.1
|
NEBL
|
nebulette |
| chr7_+_56032652 | 2.58 |
ENST00000437587.1
|
GBAS
|
glioblastoma amplified sequence |
| chr5_-_176056974 | 2.54 |
ENST00000510387.1
ENST00000506696.1 |
SNCB
|
synuclein, beta |
| chr2_+_98262497 | 2.54 |
ENST00000258424.2
|
COX5B
|
cytochrome c oxidase subunit Vb |
| chr16_-_3767506 | 2.54 |
ENST00000538171.1
|
TRAP1
|
TNF receptor-associated protein 1 |
| chr1_+_228395755 | 2.54 |
ENST00000284548.11
ENST00000570156.2 ENST00000422127.1 ENST00000366707.4 ENST00000366709.4 |
OBSCN
|
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| chr11_-_131533462 | 2.54 |
ENST00000416725.1
|
AP003039.3
|
AP003039.3 |
| chr1_+_165600436 | 2.53 |
ENST00000367888.4
ENST00000367885.1 ENST00000367884.2 |
MGST3
|
microsomal glutathione S-transferase 3 |
| chr22_-_39239987 | 2.53 |
ENST00000333039.2
|
NPTXR
|
neuronal pentraxin receptor |
| chr5_-_148033726 | 2.53 |
ENST00000354217.2
ENST00000314512.6 ENST00000362016.2 |
HTR4
|
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| chr19_+_19322758 | 2.53 |
ENST00000252575.6
|
NCAN
|
neurocan |
| chrX_+_103031758 | 2.52 |
ENST00000303958.2
ENST00000361621.2 |
PLP1
|
proteolipid protein 1 |
| chr8_+_55047763 | 2.52 |
ENST00000260102.4
ENST00000519831.1 |
MRPL15
|
mitochondrial ribosomal protein L15 |
| chrX_-_154255143 | 2.52 |
ENST00000453950.1
ENST00000423959.1 |
F8
|
coagulation factor VIII, procoagulant component |
| chr14_-_102976135 | 2.50 |
ENST00000560748.1
|
ANKRD9
|
ankyrin repeat domain 9 |
| chr1_+_42846443 | 2.49 |
ENST00000410070.2
ENST00000431473.3 |
RIMKLA
|
ribosomal modification protein rimK-like family member A |
| chr12_+_10366223 | 2.48 |
ENST00000545290.1
|
GABARAPL1
|
GABA(A) receptor-associated protein like 1 |
| chrX_+_103031421 | 2.47 |
ENST00000433491.1
ENST00000418604.1 ENST00000443502.1 |
PLP1
|
proteolipid protein 1 |
| chr19_+_35783028 | 2.47 |
ENST00000600291.1
ENST00000392213.3 |
MAG
|
myelin associated glycoprotein |
| chr11_+_12766583 | 2.45 |
ENST00000361985.2
|
TEAD1
|
TEA domain family member 1 (SV40 transcriptional enhancer factor) |
Network of associatons between targets according to the STRING database.
First level regulatory network of ESRRB_ESRRG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.4 | 45.6 | GO:1903060 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 4.3 | 12.8 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 3.5 | 24.6 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 2.6 | 44.9 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 2.4 | 7.3 | GO:1900075 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
| 2.2 | 8.7 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 2.1 | 6.4 | GO:2000276 | negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 1.8 | 5.5 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 1.8 | 12.6 | GO:0021590 | cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699) |
| 1.7 | 5.0 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 1.6 | 4.8 | GO:0050894 | determination of affect(GO:0050894) |
| 1.5 | 4.5 | GO:1990709 | maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709) |
| 1.5 | 26.4 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 1.4 | 5.6 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 1.4 | 1.4 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 1.4 | 5.4 | GO:0009386 | translational attenuation(GO:0009386) |
| 1.3 | 5.0 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 1.2 | 3.7 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 1.2 | 3.7 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.2 | 3.6 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
| 1.2 | 3.6 | GO:0072361 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) |
| 1.2 | 8.2 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 1.2 | 9.3 | GO:0086047 | membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) |
| 1.1 | 4.5 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 1.1 | 11.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 1.1 | 37.0 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 1.0 | 4.1 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 1.0 | 3.0 | GO:0021893 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 1.0 | 21.5 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.9 | 7.4 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.9 | 2.7 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.9 | 2.6 | GO:0003050 | regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050) |
| 0.9 | 2.6 | GO:2000374 | cadmium ion homeostasis(GO:0055073) regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374) |
| 0.8 | 7.9 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.7 | 1.4 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.7 | 3.5 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.7 | 7.5 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.6 | 8.1 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.6 | 3.7 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.6 | 13.4 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.6 | 2.3 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.6 | 2.9 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.6 | 8.9 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.5 | 1.6 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
| 0.5 | 40.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.5 | 6.3 | GO:0071321 | cellular response to cGMP(GO:0071321) |
| 0.5 | 1.6 | GO:0001546 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.5 | 1.6 | GO:1904925 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 0.5 | 5.0 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.5 | 6.9 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.5 | 2.4 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.5 | 2.9 | GO:0035900 | response to isolation stress(GO:0035900) |
| 0.5 | 2.3 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 0.5 | 10.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.5 | 3.2 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.4 | 18.9 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.4 | 7.1 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.4 | 1.3 | GO:0060697 | positive regulation of phospholipid catabolic process(GO:0060697) |
| 0.4 | 2.5 | GO:0036309 | protein localization to M-band(GO:0036309) |
| 0.4 | 0.8 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.4 | 5.9 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.4 | 1.6 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.4 | 1.2 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.4 | 1.9 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.4 | 0.8 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.4 | 10.8 | GO:0001976 | neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976) |
| 0.4 | 1.9 | GO:0017055 | female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.4 | 1.9 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.4 | 10.7 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.4 | 4.7 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.4 | 2.2 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.4 | 2.5 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.3 | 10.1 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.3 | 1.0 | GO:0035623 | renal glucose absorption(GO:0035623) |
| 0.3 | 4.3 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.3 | 7.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.3 | 7.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 2.5 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 26.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 1.9 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.3 | 2.8 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.3 | 10.1 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.3 | 0.6 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.3 | 1.5 | GO:0061726 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 0.3 | 2.4 | GO:0023021 | termination of signal transduction(GO:0023021) |
| 0.3 | 4.8 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.3 | 1.1 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.3 | 5.6 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.3 | 2.2 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.3 | 1.1 | GO:1902809 | regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.3 | 0.8 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 0.3 | 1.6 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.3 | 1.3 | GO:0051610 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.3 | 0.8 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.3 | 1.8 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.3 | 1.0 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.2 | 1.7 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
| 0.2 | 1.0 | GO:0097033 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.2 | 4.7 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 6.7 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.2 | 2.3 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.2 | 3.5 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.2 | 10.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.2 | 7.6 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.2 | 2.2 | GO:0042407 | cristae formation(GO:0042407) |
| 0.2 | 1.5 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) |
| 0.2 | 10.8 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.2 | 3.1 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.2 | 3.7 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.2 | 1.1 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.2 | 1.3 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 0.2 | 4.9 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.2 | 4.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.2 | 1.2 | GO:0019427 | acetate metabolic process(GO:0006083) acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542) |
| 0.2 | 0.6 | GO:0015709 | thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356) |
| 0.2 | 5.0 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 2.6 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.2 | 0.6 | GO:0018012 | N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573) |
| 0.2 | 4.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 1.0 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 0.2 | 2.2 | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.2 | 0.6 | GO:0033159 | positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) negative regulation of dendritic cell apoptotic process(GO:2000669) |
| 0.2 | 1.0 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.2 | 1.2 | GO:0070458 | cellular detoxification of nitrogen compound(GO:0070458) |
| 0.2 | 4.5 | GO:0006119 | oxidative phosphorylation(GO:0006119) |
| 0.2 | 1.0 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 3.4 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.2 | 2.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.2 | 0.9 | GO:0097286 | iron ion import(GO:0097286) |
| 0.2 | 1.6 | GO:0030242 | pexophagy(GO:0030242) |
| 0.2 | 1.8 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 1.4 | GO:0010731 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.2 | 1.9 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.2 | 1.2 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 1.0 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.2 | 3.1 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.2 | 0.6 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 0.2 | 0.6 | GO:0010615 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.2 | 5.1 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.2 | 0.9 | GO:1901908 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.2 | 1.5 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.2 | 0.5 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 1.8 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.1 | 0.6 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.1 | 2.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 1.0 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.1 | 12.0 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 3.0 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 0.4 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.1 | 0.7 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
| 0.1 | 9.1 | GO:0090004 | positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.1 | 2.6 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 0.5 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 0.1 | 4.7 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.1 | 1.2 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 0.5 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.1 | 2.5 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.1 | 6.1 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 1.4 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 1.4 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 0.1 | 1.8 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.1 | 9.9 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.1 | 10.8 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 2.3 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.1 | 1.2 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.1 | 2.1 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.1 | 5.9 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 2.5 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.1 | 1.8 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.1 | 2.3 | GO:0006705 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.1 | 9.3 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.1 | 3.4 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.1 | 0.8 | GO:0033216 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.1 | 0.4 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 1.7 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 2.9 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 1.5 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.1 | 2.5 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.1 | 0.4 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.1 | 0.8 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.1 | 1.9 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.1 | 1.6 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 3.2 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.1 | 2.5 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.1 | 0.4 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.1 | 1.6 | GO:0009790 | embryo development(GO:0009790) |
| 0.1 | 1.8 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 3.5 | GO:0097237 | cellular response to toxic substance(GO:0097237) |
| 0.1 | 0.8 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 1.0 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 3.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 7.4 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.1 | 0.5 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.1 | 2.3 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 1.0 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.1 | 9.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 0.7 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.6 | GO:0051105 | regulation of DNA ligation(GO:0051105) |
| 0.1 | 0.6 | GO:0060356 | tryptophan transport(GO:0015827) leucine import(GO:0060356) |
| 0.1 | 2.0 | GO:0014733 | regulation of skeletal muscle adaptation(GO:0014733) |
| 0.1 | 0.8 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 2.0 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 1.2 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.1 | 7.5 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.1 | 0.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 0.3 | GO:0002426 | immunoglobulin production in mucosal tissue(GO:0002426) |
| 0.1 | 4.1 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.1 | 0.5 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 4.8 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 0.2 | GO:0061304 | cerebellum vasculature development(GO:0061300) retinal blood vessel morphogenesis(GO:0061304) |
| 0.1 | 0.8 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 1.9 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 1.3 | GO:1901642 | nucleoside transmembrane transport(GO:1901642) |
| 0.1 | 9.0 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.1 | 0.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.1 | 0.1 | GO:0015677 | copper ion import(GO:0015677) |
| 0.1 | 0.6 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.1 | 2.2 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
| 0.1 | 1.2 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.1 | 1.8 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
| 0.1 | 5.4 | GO:0005977 | glycogen metabolic process(GO:0005977) |
| 0.1 | 0.9 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 3.1 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.1 | 1.8 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 2.5 | GO:0042417 | dopamine metabolic process(GO:0042417) |
| 0.1 | 2.4 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.1 | 1.3 | GO:0032754 | positive regulation of interleukin-5 production(GO:0032754) |
| 0.1 | 4.1 | GO:0009142 | nucleoside triphosphate biosynthetic process(GO:0009142) |
| 0.1 | 1.4 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 0.7 | GO:0048511 | rhythmic process(GO:0048511) |
| 0.1 | 1.1 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 1.0 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 1.8 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.0 | 1.4 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.8 | GO:0003299 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.8 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 1.1 | GO:0031214 | biomineral tissue development(GO:0031214) |
| 0.0 | 1.2 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.0 | 0.5 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.0 | 2.2 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.0 | 2.6 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 3.3 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.0 | 0.5 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.0 | 0.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.0 | 1.1 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 1.9 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.0 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.2 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.0 | 2.6 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 1.8 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 0.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 1.2 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.0 | 1.4 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.9 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 0.3 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.0 | 0.7 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.0 | 2.0 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.2 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.4 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.0 | 0.1 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.0 | 0.3 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.0 | 1.0 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 0.0 | 0.3 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.0 | 0.6 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.0 | 0.3 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.5 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 2.2 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 2.9 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.0 | 0.6 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.0 | 0.4 | GO:0033139 | regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) |
| 0.0 | 0.3 | GO:1901991 | negative regulation of mitotic cell cycle phase transition(GO:1901991) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.4 | GO:0034205 | beta-amyloid formation(GO:0034205) |
| 0.0 | 1.3 | GO:0035825 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 1.2 | GO:0010389 | regulation of G2/M transition of mitotic cell cycle(GO:0010389) |
| 0.0 | 3.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 2.5 | GO:0008652 | cellular amino acid biosynthetic process(GO:0008652) |
| 0.0 | 0.9 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.3 | GO:0035404 | histone-serine phosphorylation(GO:0035404) |
| 0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 1.8 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 0.2 | GO:0010226 | response to lithium ion(GO:0010226) |
| 0.0 | 1.0 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.2 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 0.5 | GO:0051898 | negative regulation of protein kinase B signaling(GO:0051898) |
| 0.0 | 0.3 | GO:0007501 | mesodermal cell fate specification(GO:0007501) |
| 0.0 | 1.1 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.0 | 0.0 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.0 | 0.4 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 4.1 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 1.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.1 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 2.0 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 0.5 | GO:0035094 | response to nicotine(GO:0035094) |
| 0.0 | 0.5 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 7.7 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.0 | 0.1 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.0 | 1.4 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.0 | 0.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.2 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
| 0.0 | 0.5 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 0.6 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.6 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 1.1 | GO:0090002 | establishment of protein localization to plasma membrane(GO:0090002) |
| 0.0 | 0.1 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.6 | GO:0005745 | m-AAA complex(GO:0005745) |
| 2.6 | 15.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 2.4 | 7.1 | GO:1990015 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 2.1 | 6.3 | GO:0098855 | HCN channel complex(GO:0098855) |
| 1.5 | 5.9 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 1.4 | 16.7 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.3 | 16.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 1.1 | 39.4 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 1.0 | 6.0 | GO:0070470 | plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470) |
| 0.9 | 26.0 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.8 | 11.0 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.8 | 11.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.8 | 5.6 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.7 | 5.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.6 | 2.6 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.6 | 2.5 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.6 | 2.3 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.6 | 4.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.5 | 4.2 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.5 | 4.5 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.5 | 4.8 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.4 | 3.9 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.4 | 7.3 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 0.4 | 2.4 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.4 | 28.7 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.4 | 14.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.4 | 3.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.4 | 1.9 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.4 | 3.7 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.4 | 3.3 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.4 | 9.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 1.0 | GO:0097489 | multivesicular body, internal vesicle lumen(GO:0097489) |
| 0.3 | 1.7 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.3 | 10.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.3 | 3.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.3 | 4.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.3 | 1.6 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.2 | 1.9 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.2 | 2.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.2 | 1.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.2 | 0.5 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.2 | 15.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 0.7 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.2 | 1.6 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.2 | 13.6 | GO:0031430 | M band(GO:0031430) |
| 0.2 | 7.0 | GO:0031672 | A band(GO:0031672) |
| 0.2 | 2.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.2 | 4.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 5.9 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.2 | 2.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 4.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 7.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.2 | 3.2 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 11.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.2 | 0.3 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.2 | 6.4 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.2 | 84.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 0.5 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.1 | 1.3 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.1 | 0.8 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 3.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 7.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 1.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 1.6 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 10.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 41.2 | GO:0030016 | myofibril(GO:0030016) |
| 0.1 | 2.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 1.0 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 30.1 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 1.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 2.4 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 13.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 5.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 4.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 3.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 29.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 20.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 2.0 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 1.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 3.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 7.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 4.4 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 2.1 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.1 | GO:0044753 | amphisome(GO:0044753) |
| 0.1 | 0.9 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 2.0 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 0.7 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 5.1 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.3 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 9.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 11.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 0.3 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.0 | 0.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 46.0 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 3.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 1.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 3.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 4.8 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.5 | GO:0030126 | COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663) |
| 0.0 | 3.0 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 1.3 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 5.0 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.8 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 5.9 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 6.8 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 4.3 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 10.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.4 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 1.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 3.7 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.1 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.0 | 3.9 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 1.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 4.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 1.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.3 | GO:0060170 | ciliary membrane(GO:0060170) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 44.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 2.9 | 8.6 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 2.5 | 7.5 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 2.4 | 16.7 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 2.3 | 9.3 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 2.0 | 11.9 | GO:0051373 | FATZ binding(GO:0051373) |
| 2.0 | 5.9 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
| 1.9 | 15.3 | GO:0030172 | troponin C binding(GO:0030172) |
| 1.6 | 4.8 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
| 1.4 | 5.5 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 1.4 | 4.1 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 1.3 | 9.1 | GO:0043532 | angiostatin binding(GO:0043532) |
| 1.3 | 6.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 1.0 | 8.2 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 1.0 | 3.1 | GO:0072510 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 1.0 | 24.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 1.0 | 5.0 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.9 | 3.6 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.8 | 5.9 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.8 | 9.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.8 | 24.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.8 | 4.1 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.8 | 4.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.7 | 4.4 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.7 | 10.0 | GO:0052658 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.7 | 5.3 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.7 | 3.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.6 | 7.1 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.6 | 2.5 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.6 | 2.5 | GO:0072590 | N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) |
| 0.6 | 4.8 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.6 | 2.3 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.6 | 4.6 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.6 | 20.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.6 | 2.3 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.5 | 2.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.5 | 1.6 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.5 | 18.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.5 | 2.5 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.5 | 12.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.5 | 29.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.5 | 1.9 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.5 | 2.3 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
| 0.5 | 1.4 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.5 | 3.7 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.4 | 1.3 | GO:0032440 | 2-alkenal reductase [NAD(P)] activity(GO:0032440) |
| 0.4 | 2.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.4 | 3.7 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.4 | 6.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.4 | 4.0 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.4 | 2.3 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.4 | 3.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.4 | 1.1 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.4 | 16.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.4 | 1.1 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) |
| 0.3 | 9.1 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.3 | 4.0 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.3 | 6.6 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.3 | 2.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.3 | 2.8 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.3 | 2.4 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.3 | 5.6 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.3 | 8.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.3 | 1.7 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.3 | 1.1 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.3 | 3.6 | GO:0015288 | porin activity(GO:0015288) |
| 0.3 | 3.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.3 | 1.9 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.3 | 1.6 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.3 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.3 | 5.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.3 | 2.6 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.3 | 4.9 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.3 | 1.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.2 | 7.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 6.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.2 | 2.9 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.2 | 5.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 0.9 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.2 | 0.7 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.2 | 0.9 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.2 | 0.9 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.2 | 2.0 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.2 | 0.6 | GO:0015131 | thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) |
| 0.2 | 1.8 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.2 | 1.0 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.2 | 3.3 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.2 | 1.5 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.2 | 0.6 | GO:1990698 | palmitoleoyltransferase activity(GO:1990698) |
| 0.2 | 1.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 0.9 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.2 | 2.0 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 1.2 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.2 | 1.9 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 14.9 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.2 | 0.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.2 | 6.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 5.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 2.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 1.9 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.2 | 2.0 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 1.0 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.2 | 2.3 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.2 | 3.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 1.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.2 | 1.2 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.2 | 0.6 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.2 | 1.5 | GO:0046790 | complement component C1q binding(GO:0001849) virion binding(GO:0046790) |
| 0.2 | 0.9 | GO:0034432 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.2 | 1.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 1.5 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.2 | 2.0 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.2 | 0.6 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.1 | 1.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 3.7 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 1.0 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.6 | GO:0002134 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.1 | 0.7 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 4.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.6 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.1 | 1.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 2.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 2.0 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.1 | 4.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.9 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 2.1 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 1.9 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 2.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 1.5 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 7.6 | GO:0043531 | ADP binding(GO:0043531) |
| 0.1 | 1.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 1.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 4.0 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 1.0 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 1.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 3.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.8 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.1 | 2.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.5 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 5.9 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 4.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 1.0 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 0.3 | GO:0047225 | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225) |
| 0.1 | 15.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 2.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.1 | 2.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 4.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 5.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.6 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.8 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
| 0.1 | 2.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 1.2 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 2.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.8 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.1 | 8.8 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 1.7 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 0.5 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.1 | 0.6 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 0.4 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 0.4 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.1 | 1.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 1.7 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 1.1 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.1 | 2.0 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.3 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 1.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.1 | 1.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 3.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 3.7 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 4.2 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 1.0 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 1.6 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 0.8 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.8 | GO:0008526 | phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 17.9 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.6 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 2.4 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 14.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 2.1 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 1.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 6.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.2 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
| 0.0 | 0.6 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.0 | 0.5 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 2.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 1.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 5.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 1.1 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 7.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 4.3 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 1.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.0 | 0.9 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.0 | 1.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 4.7 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 1.9 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.6 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 1.2 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 2.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.0 | 1.5 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.9 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.8 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.6 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 2.2 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.3 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.0 | 1.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 2.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.5 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.5 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 5.4 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.0 | 2.2 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.0 | 3.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 1.4 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.7 | GO:0015405 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.8 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) |
| 0.0 | 0.2 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 5.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 1.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.6 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.0 | 0.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 2.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.6 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 7.7 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.2 | 7.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 9.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 20.7 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 22.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 4.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 5.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 2.4 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 1.6 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 4.1 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 1.7 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 3.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 9.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 3.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 3.3 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 7.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 5.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 0.3 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 2.0 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 2.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 1.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 2.3 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 3.7 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.6 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 1.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 5.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 2.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.8 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 3.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.6 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.1 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.7 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 1.2 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.2 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.5 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 1.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.8 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.2 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 26.2 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.7 | 63.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.5 | 31.4 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.5 | 34.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.4 | 11.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.4 | 10.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.4 | 9.9 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.3 | 1.0 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.3 | 6.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.3 | 4.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.3 | 16.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.3 | 10.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.3 | 5.4 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.3 | 4.3 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.2 | 7.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.2 | 3.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.2 | 2.3 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.2 | 7.3 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 31.5 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 9.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 7.2 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.2 | 63.2 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 2.4 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.2 | 6.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 8.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 3.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 1.9 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 6.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 4.2 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 3.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 12.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.6 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 3.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 0.6 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.1 | 0.8 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 4.1 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 2.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 5.5 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.1 | 1.5 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 4.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.9 | REACTOME BOTULINUM NEUROTOXICITY | Genes involved in Botulinum neurotoxicity |
| 0.1 | 2.0 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 4.6 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 2.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 1.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 3.0 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.5 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.1 | 1.0 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.1 | 2.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 8.5 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 2.0 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 5.2 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.2 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 1.1 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 1.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.6 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 0.6 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 0.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 1.6 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 2.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 4.3 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 4.3 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 2.1 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.1 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.7 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 4.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 3.9 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.7 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 1.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 2.8 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.1 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 0.9 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |