Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for FIGLA
Z-value: 1.59
Motif logo
Transcription factors associated with FIGLA
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FIGLA | hg19_v2_chr2_-_71017775_71017775 | 0.44 | 1.2e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_39258461 Show fit | 4.74 |
ENST00000440582.1
|
keratin associated protein 4-16, pseudogene |
|
| chr2_-_152590946 Show fit | 3.14 |
ENST00000172853.10
|
nebulin |
|
| chr16_-_11375179 Show fit | 3.03 |
ENST00000312511.3
|
protamine 1 |
|
| chr19_+_50936142 Show fit | 2.92 |
ENST00000357701.5
|
myosin binding protein C, fast type |
|
| chr7_-_27196267 Show fit | 2.50 |
ENST00000242159.3
|
homeobox A7 |
|
| chr17_-_39324424 Show fit | 2.37 |
ENST00000391356.2
|
keratin associated protein 4-3 |
|
| chr1_-_201391149 Show fit | 2.33 |
ENST00000555948.1
ENST00000556362.1 |
troponin I type 1 (skeletal, slow) |
|
| chr17_-_7165662 Show fit | 2.20 |
ENST00000571881.2
ENST00000360325.7 |
claudin 7 |
|
| chr17_+_48133459 Show fit | 2.15 |
ENST00000320031.8
|
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
|
| chr3_-_50383096 Show fit | 2.06 |
ENST00000442887.1
ENST00000360165.3 |
zinc finger, MYND-type containing 10 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FIGLA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.4 | GO:0031424 | keratinization(GO:0031424) |
| 1.0 | 5.1 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 4.1 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.6 | 3.5 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.4 | 3.5 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.2 | 3.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 3.0 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.4 | 2.8 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
| 0.8 | 2.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.6 | 2.5 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.8 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 6.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.8 | 4.1 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 0.0 | 4.0 | GO:0030017 | sarcomere(GO:0030017) |
| 0.3 | 3.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 3.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 3.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 3.0 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.8 | 2.4 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.0 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 6.5 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 5.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 4.5 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 4.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 3.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 3.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 3.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 3.5 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 3.3 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 2.9 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 2.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 2.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 2.1 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 2.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.8 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 1.7 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 1.7 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 1.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 4.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 3.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 3.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 2.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 2.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.9 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 1.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.5 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 1.4 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |