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Illumina Body Map 2: averaged replicates

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Results for FOSL1

Z-value: 2.73

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
FOSL1
ENSG00000175592.4 FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg19_v2_chr11_-_65667884_656678950.568.8e-04Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_394196 9.28 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr19_-_56056888 7.66 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr17_-_39769005 7.06 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr1_-_95007193 6.32 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr7_+_73245193 6.12 ENST00000340958.2
CLDN4
claudin 4
chr2_+_27505260 5.91 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr10_-_76868931 5.38 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr20_-_62129163 5.37 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr2_+_170366203 5.34 ENST00000284669.1
KLHL41
kelch-like family member 41
chr17_+_4853442 4.98 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr10_-_21463116 4.76 ENST00000417816.2
NEBL
nebulette
chr4_+_120056939 4.74 ENST00000307128.5
MYOZ2
myozenin 2
chr16_-_14109841 4.69 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
CTD-2135D7.5
chr10_-_76868866 4.68 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr3_-_39234074 4.49 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr8_-_82395461 4.32 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr10_+_24755416 4.21 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr9_+_34992846 4.19 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr11_-_102714534 4.19 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr16_-_2908155 4.12 ENST00000571228.1
ENST00000161006.3
PRSS22
protease, serine, 22
chrX_-_33229429 4.09 ENST00000420596.1
ENST00000448370.1
DMD
dystrophin
chr5_+_150020240 4.06 ENST00000519664.1
SYNPO
synaptopodin
chr11_+_394145 4.04 ENST00000528036.1
PKP3
plakophilin 3
chr12_-_91573249 4.04 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr19_+_50706866 4.00 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr10_+_88428370 3.93 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr12_+_13349711 3.91 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr12_+_13349650 3.89 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr11_-_111783919 3.81 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr10_-_75423560 3.80 ENST00000606523.1
SYNPO2L
synaptopodin 2-like
chr15_+_51633826 3.76 ENST00000335449.6
GLDN
gliomedin
chr11_-_47207390 3.75 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr11_-_111784005 3.69 ENST00000527899.1
CRYAB
crystallin, alpha B
chr7_+_30960915 3.61 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr16_-_69760409 3.59 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr12_-_91573132 3.56 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr19_-_46285646 3.56 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr17_-_39743139 3.55 ENST00000167586.6
KRT14
keratin 14
chr12_-_56101647 3.39 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
ITGA7
integrin, alpha 7
chr19_-_36019123 3.39 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr10_+_88428206 3.33 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr11_-_10920714 3.29 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr11_-_111794446 3.25 ENST00000527950.1
CRYAB
crystallin, alpha B
chr3_-_149293990 3.16 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr12_-_91573316 3.14 ENST00000393155.1
DCN
decorin
chr19_+_38794797 3.13 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr5_-_41794663 3.09 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr17_-_39781054 3.07 ENST00000463128.1
KRT17
keratin 17
chr11_-_47206965 3.04 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr10_+_123872483 3.03 ENST00000369001.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr17_-_39780634 3.02 ENST00000577817.2
KRT17
keratin 17
chr1_-_153029980 2.99 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr8_+_120220561 2.98 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr14_+_69726656 2.97 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr10_+_24544249 2.97 ENST00000430453.2
KIAA1217
KIAA1217
chr20_-_44455976 2.96 ENST00000372555.3
TNNC2
troponin C type 2 (fast)
chr3_-_46608010 2.96 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr1_+_183155373 2.91 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr17_-_39780819 2.91 ENST00000311208.8
KRT17
keratin 17
chr12_+_48152774 2.87 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr21_-_36421626 2.80 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr5_-_41794313 2.80 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr10_-_4285923 2.73 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr19_-_35992780 2.68 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr19_+_6740888 2.67 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr10_-_4285835 2.64 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr1_-_158656488 2.61 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_+_101983176 2.59 ENST00000524575.1
YAP1
Yes-associated protein 1
chr7_+_23286182 2.57 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr1_-_153066998 2.56 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr21_-_36421535 2.54 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr7_-_107643567 2.52 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr11_+_393428 2.51 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr6_+_47666275 2.49 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr1_+_152956549 2.49 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr20_+_34742650 2.49 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr14_+_69726864 2.48 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr13_+_78109884 2.47 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr16_+_30077055 2.45 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr8_+_125860939 2.44 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr18_+_55888767 2.43 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chrX_-_33229636 2.43 ENST00000357033.4
DMD
dystrophin
chr16_+_58533951 2.42 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr14_+_69726968 2.40 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr7_+_28448995 2.38 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr1_+_27719148 2.38 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr9_-_112179990 2.37 ENST00000394827.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr17_-_9694614 2.35 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr12_+_10366223 2.35 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_4347271 2.34 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr1_+_156084461 2.31 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr1_+_27189631 2.30 ENST00000339276.4
SFN
stratifin
chr7_+_79998864 2.29 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr19_-_36004543 2.29 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr1_-_153013588 2.28 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr12_+_10365082 2.27 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_+_39279838 2.26 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr2_+_36923830 2.24 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr11_-_102401469 2.22 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr9_-_97356075 2.22 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr16_+_30077098 2.22 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr12_+_10365404 2.21 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chrX_-_15511438 2.21 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr12_-_48152853 2.19 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr3_+_174158732 2.17 ENST00000434257.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr7_+_116312411 2.17 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr7_-_107643674 2.15 ENST00000222399.6
LAMB1
laminin, beta 1
chr17_+_21191341 2.14 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr1_-_43751276 2.13 ENST00000423420.1
C1orf210
chromosome 1 open reading frame 210
chr17_-_53800217 2.13 ENST00000424486.2
TMEM100
transmembrane protein 100
chr6_-_46293378 2.13 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr13_-_36429763 2.12 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_+_159727222 2.11 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr12_-_48152611 2.11 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr21_-_43786634 2.09 ENST00000291527.2
TFF1
trefoil factor 1
chr21_-_36421401 2.07 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr5_+_53751445 2.07 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr8_+_79503458 2.06 ENST00000518467.1
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr13_+_53602894 2.05 ENST00000219022.2
OLFM4
olfactomedin 4
chr16_+_1306060 2.04 ENST00000397534.2
TPSD1
tryptase delta 1
chrX_-_74742846 2.04 ENST00000373361.3
ZDHHC15
zinc finger, DHHC-type containing 15
chr1_-_115880852 2.01 ENST00000369512.2
NGF
nerve growth factor (beta polypeptide)
chr3_+_69928256 1.99 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr11_-_65667997 1.98 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr12_+_10366016 1.95 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_-_11918988 1.95 ENST00000376468.3
NPPB
natriuretic peptide B
chr1_+_153003671 1.94 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr7_+_55177416 1.94 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr10_-_93392811 1.92 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr5_+_150020214 1.90 ENST00000307662.4
SYNPO
synaptopodin
chr11_-_8739566 1.90 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr9_-_91793675 1.87 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_-_42276612 1.86 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr4_+_169753156 1.86 ENST00000393726.3
ENST00000507735.1
PALLD
palladin, cytoskeletal associated protein
chr3_-_149095652 1.85 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr16_+_2083265 1.85 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_+_150480551 1.84 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr13_+_102142296 1.83 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_220495800 1.83 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr12_-_56236711 1.82 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr1_+_198189921 1.82 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr7_+_22766766 1.82 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_209824643 1.82 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr11_-_8739383 1.80 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr16_+_1306093 1.80 ENST00000211076.3
TPSD1
tryptase delta 1
chr13_+_78109804 1.78 ENST00000535157.1
SCEL
sciellin
chr5_-_149535190 1.78 ENST00000517488.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_+_74405501 1.77 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr5_-_149535421 1.77 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_218766698 1.76 ENST00000439083.1
TNS1
tensin 1
chr1_+_39670360 1.75 ENST00000494012.1
MACF1
microtubule-actin crosslinking factor 1
chr12_+_110718921 1.75 ENST00000308664.6
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr3_+_156807663 1.73 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr8_+_70476088 1.73 ENST00000525999.1
SULF1
sulfatase 1
chr3_+_155860751 1.72 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_+_12042015 1.72 ENST00000412236.1
MFN2
mitofusin 2
chr5_+_140729649 1.72 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr3_-_151034734 1.71 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr11_-_65667884 1.71 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr3_-_73483055 1.71 ENST00000479530.1
PDZRN3
PDZ domain containing ring finger 3
chr19_-_46285736 1.70 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr1_-_12679171 1.69 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr7_-_135433534 1.67 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chr9_+_124329336 1.66 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr1_-_6659876 1.65 ENST00000496707.1
KLHL21
kelch-like family member 21
chr10_+_121410882 1.65 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr11_-_6341844 1.65 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr1_+_150480576 1.64 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr8_-_72268721 1.64 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_135433460 1.62 ENST00000415751.1
FAM180A
family with sequence similarity 180, member A
chr11_-_6341724 1.61 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr3_+_112930946 1.60 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr6_-_84140757 1.60 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_+_99899180 1.59 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr11_-_62457371 1.59 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr6_+_74405804 1.59 ENST00000287097.5
CD109
CD109 molecule
chr6_+_125540951 1.58 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr14_-_23624511 1.52 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_-_62323702 1.52 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr1_+_156096336 1.52 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr1_+_152881014 1.51 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr11_+_57531292 1.50 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr3_+_112930387 1.48 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr10_+_17270214 1.45 ENST00000544301.1
VIM
vimentin
chr18_+_21452804 1.44 ENST00000269217.6
LAMA3
laminin, alpha 3
chr2_-_65593784 1.44 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr2_+_68872954 1.44 ENST00000394342.2
PROKR1
prokineticin receptor 1
chr4_+_159727272 1.43 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr11_-_71781096 1.42 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr19_-_35981358 1.42 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr11_+_34643600 1.42 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr3_+_167584414 1.42 ENST00000475324.1
RP11-298O21.2
RP11-298O21.2
chr12_-_53297432 1.41 ENST00000546900.1
KRT8
keratin 8
chr3_-_194090460 1.40 ENST00000428839.1
ENST00000347624.3
LRRC15
leucine rich repeat containing 15
chr8_+_22844995 1.40 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr12_-_56236690 1.40 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr18_+_31185530 1.39 ENST00000586327.1
ASXL3
additional sex combs like 3 (Drosophila)
chr2_+_47596287 1.38 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr6_-_56819385 1.36 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr18_+_21452964 1.36 ENST00000587184.1
LAMA3
laminin, alpha 3

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.7 16.8 GO:0002159 desmosome assembly(GO:0002159)
1.2 3.6 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.2 3.5 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
1.0 6.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.9 4.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 4.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.9 4.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.8 2.5 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.8 12.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 2.5 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.8 11.8 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7 5.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.7 5.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.6 1.9 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.6 2.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.6 2.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.5 2.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.5 1.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.5 16.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.5 3.7 GO:0007296 vitellogenesis(GO:0007296)
0.5 1.8 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.4 4.4 GO:0001554 luteolysis(GO:0001554)
0.4 10.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 3.4 GO:0072675 osteoclast fusion(GO:0072675)
0.4 7.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 8.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 11.0 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.4 0.7 GO:1903524 positive regulation of vasoconstriction(GO:0045907) positive regulation of blood circulation(GO:1903524)
0.4 2.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 0.7 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.4 1.1 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.3 2.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 1.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 6.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 12.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 4.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.0 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 3.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 2.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 1.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.9 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 5.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.3 1.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3 6.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 1.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 4.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 5.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.3 1.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.3 7.8 GO:0032060 bleb assembly(GO:0032060)
0.3 2.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 5.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 1.6 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 0.7 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 2.4 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 3.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 2.3 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 2.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 2.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 3.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.3 GO:0002934 desmosome organization(GO:0002934)
0.2 3.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 2.6 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 7.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 1.7 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 12.0 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 1.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 2.9 GO:0015886 heme transport(GO:0015886)
0.2 3.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 0.8 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 2.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 0.5 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 4.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 5.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.8 GO:0030421 defecation(GO:0030421)
0.1 2.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 1.4 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 2.5 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 2.4 GO:0060973 cell migration involved in heart development(GO:0060973)
0.1 0.6 GO:0044650 adhesion of symbiont to host cell(GO:0044650)
0.1 0.8 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 3.8 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 11.1 GO:0030239 myofibril assembly(GO:0030239)
0.1 1.6 GO:0044351 macropinocytosis(GO:0044351)
0.1 3.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.3 GO:0031394 maternal aggressive behavior(GO:0002125) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.2 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 2.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 2.2 GO:0044849 estrous cycle(GO:0044849)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.3 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.9 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.8 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.7 GO:0060539 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.8 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 3.5 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 2.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 1.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 2.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 1.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.1 GO:0051964 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.1 1.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 3.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 2.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.9 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 1.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 1.4 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.0 GO:0006825 copper ion transport(GO:0006825)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.9 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 3.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 2.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.7 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 2.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 9.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) axon midline choice point recognition(GO:0016199) cellular response to norepinephrine stimulus(GO:0071874)
0.0 2.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.7 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 3.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.5 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.5 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.5 GO:0015695 organic cation transport(GO:0015695)
0.0 3.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 1.1 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.8 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 2.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.4 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 0.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 1.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 3.0 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 2.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 4.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 2.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 4.0 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.2 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0 0.4 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.1 GO:0009798 axis specification(GO:0009798)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.8 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 1.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 4.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.0 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 1.4 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.0 0.1 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 1.6 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0097444 spine apparatus(GO:0097444)
1.9 7.6 GO:0005607 laminin-2 complex(GO:0005607)
1.2 3.6 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.8 4.7 GO:0097513 myosin II filament(GO:0097513)
0.7 10.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 1.9 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.6 10.7 GO:0097512 cardiac myofibril(GO:0097512)
0.6 1.7 GO:1990032 parallel fiber(GO:1990032)
0.5 18.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 6.5 GO:0016013 syntrophin complex(GO:0016013)
0.5 2.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.5 2.0 GO:1902912 pyruvate kinase complex(GO:1902912)
0.4 4.5 GO:0005638 lamin filament(GO:0005638)
0.4 15.0 GO:0031143 pseudopodium(GO:0031143)
0.4 1.3 GO:0034515 proteasome storage granule(GO:0034515)
0.4 4.6 GO:0005610 laminin-5 complex(GO:0005610)
0.4 5.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 3.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 13.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 0.6 GO:0044753 amphisome(GO:0044753)
0.3 2.9 GO:0032437 cuticular plate(GO:0032437)
0.3 10.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 17.6 GO:0001533 cornified envelope(GO:0001533)
0.2 2.4 GO:0005827 polar microtubule(GO:0005827)
0.2 1.4 GO:0031673 H zone(GO:0031673)
0.2 3.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 7.0 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 2.5 GO:0097470 ribbon synapse(GO:0097470)
0.1 3.0 GO:0005861 troponin complex(GO:0005861)
0.1 1.4 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 5.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 4.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 33.1 GO:0031674 I band(GO:0031674)
0.1 2.2 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 3.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:0033263 CORVET complex(GO:0033263)
0.1 2.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 2.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 1.5 GO:0043034 costamere(GO:0043034)
0.1 1.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 12.9 GO:0005882 intermediate filament(GO:0005882)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.2 GO:0097227 sperm annulus(GO:0097227)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 3.6 GO:0031941 filamentous actin(GO:0031941)
0.1 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.9 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0070652 HAUS complex(GO:0070652)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0098858 actin-based cell projection(GO:0098858)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 3.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 3.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.9 GO:0030175 filopodium(GO:0030175)
0.0 6.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 3.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 3.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.3 GO:0005844 polysome(GO:0005844)
0.0 1.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 6.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0043234 protein complex(GO:0043234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
1.2 3.6 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.2 3.6 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
1.1 9.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 3.5 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.8 2.5 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.8 4.7 GO:0051373 FATZ binding(GO:0051373)
0.7 5.0 GO:1990254 keratin filament binding(GO:1990254)
0.6 15.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 2.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.6 2.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.6 2.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5 3.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 8.8 GO:0030957 Tat protein binding(GO:0030957)
0.4 6.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.4 4.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 1.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 3.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 1.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 5.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 2.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.3 2.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 6.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 1.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.3 7.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.6 GO:0045545 syndecan binding(GO:0045545)
0.2 9.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 4.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.6 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 3.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 2.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.6 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.2 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 5.7 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 6.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 3.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 2.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.8 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 1.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 3.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.1 5.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.9 GO:0050436 microfibril binding(GO:0050436)
0.1 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 10.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 3.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:1990175 EH domain binding(GO:1990175)
0.1 1.5 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 10.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 4.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 2.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:1903135 cupric ion binding(GO:1903135)
0.1 2.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 12.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 4.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.3 GO:0048156 tau protein binding(GO:0048156)
0.1 2.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.7 GO:0070402 NADPH binding(GO:0070402)
0.1 1.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.3 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 8.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 3.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 49.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 5.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 9.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 11.9 GO:0003779 actin binding(GO:0003779)
0.0 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 3.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 3.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 18.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 18.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 9.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 10.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 5.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.0 PID IGF1 PATHWAY IGF1 pathway
0.1 6.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.2 PID AURORA A PATHWAY Aurora A signaling
0.0 13.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 2.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 5.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.2 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 3.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 1.5 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.2 7.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 9.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 10.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 6.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 6.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 4.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 8.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 5.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 10.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 6.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 3.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 5.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 8.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants