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Illumina Body Map 2: averaged replicates

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Results for FOSL2_SMARCC1

Z-value: 3.79

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
ENSG00000075426.7 FOSL2
ENSG00000173473.6 SMARCC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v2_chr2_+_28615669_286157330.477.2e-03Click!
SMARCC1hg19_v2_chr3_-_47823298_478234230.192.9e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_89901292 23.28 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr7_+_73245193 15.42 ENST00000340958.2
CLDN4
claudin 4
chr2_+_89998789 15.33 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr2_+_90192768 15.13 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr2_-_89521942 14.74 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr2_-_89417335 14.46 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr2_+_89999259 13.87 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr22_+_23134974 13.45 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr2_-_89399845 13.24 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr22_+_23241661 12.14 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr22_+_22723969 11.44 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr22_+_23029188 11.39 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_23077065 11.36 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr18_+_21452964 11.35 ENST00000587184.1
LAMA3
laminin, alpha 3
chr18_+_21452804 11.29 ENST00000269217.6
LAMA3
laminin, alpha 3
chr2_+_90139056 11.02 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr2_-_89340242 10.98 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr2_+_90121477 10.78 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr22_+_23010756 10.64 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr22_+_22735135 10.54 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr17_-_39769005 9.84 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr8_-_82395461 9.83 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr2_+_89952792 9.71 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr2_-_89568263 9.65 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr7_+_30960915 9.31 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr2_-_89459813 8.77 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr22_+_23089870 8.44 ENST00000390311.2
IGLV3-16
immunoglobulin lambda variable 3-16
chr22_+_22569155 8.22 ENST00000390287.2
IGLV10-54
immunoglobulin lambda variable 10-54
chr2_-_89619904 7.74 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr22_+_23063100 7.11 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr2_+_89923550 7.02 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr2_+_90198535 6.94 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr22_+_22453093 6.66 ENST00000390283.2
IGLV8-61
immunoglobulin lambda variable 8-61
chr11_-_68780824 6.12 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr22_+_23165153 6.05 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr22_+_22749343 6.00 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr1_-_153521714 5.87 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr19_+_46009837 5.86 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr6_+_41604747 5.80 ENST00000419164.1
ENST00000373051.2
MDFI
MyoD family inhibitor
chr22_+_22730353 5.75 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr1_-_153521597 5.67 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr22_+_22550113 5.53 ENST00000390285.3
IGLV6-57
immunoglobulin lambda variable 6-57
chr2_+_90060377 5.45 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr20_+_44637526 5.18 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr22_+_22712087 5.14 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr22_+_23154239 5.03 ENST00000390315.2
IGLV3-10
immunoglobulin lambda variable 3-10
chr1_-_151965048 5.01 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr1_-_223853425 4.97 ENST00000366873.2
ENST00000419193.2
CAPN8
calpain 8
chr5_+_150020214 4.94 ENST00000307662.4
SYNPO
synaptopodin
chr6_+_41604620 4.91 ENST00000432027.1
MDFI
MyoD family inhibitor
chr1_+_156084461 4.82 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr1_-_203198790 4.82 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr22_+_23040274 4.75 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr4_+_74606223 4.74 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_+_41136216 4.68 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr22_+_22781853 4.58 ENST00000390300.2
IGLV5-37
immunoglobulin lambda variable 5-37
chr16_-_30125177 4.57 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_-_223853348 4.55 ENST00000366872.5
CAPN8
calpain 8
chr2_+_113875466 4.52 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
IL1RN
interleukin 1 receptor antagonist
chr15_+_41136586 4.46 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_+_393428 4.41 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr5_-_141061777 4.35 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr13_+_102142296 4.32 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_87754989 4.30 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr19_-_35992780 4.26 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr2_+_87755054 4.24 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_+_17270214 4.19 ENST00000544301.1
VIM
vimentin
chr5_-_141061759 4.18 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_102668879 4.18 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr21_+_10862622 4.16 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_+_87754887 4.14 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr6_-_31704282 4.09 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr8_+_70476088 4.07 ENST00000525999.1
SULF1
sulfatase 1
chr1_+_27189631 4.06 ENST00000339276.4
SFN
stratifin
chr17_-_38721711 4.06 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr12_-_48152611 3.98 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr19_-_44174330 3.97 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr16_+_1290694 3.91 ENST00000338844.3
TPSAB1
tryptase alpha/beta 1
chr19_-_44174305 3.91 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr11_+_101983176 3.90 ENST00000524575.1
YAP1
Yes-associated protein 1
chr3_+_36421971 3.88 ENST00000457375.2
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr12_-_56236734 3.84 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chrX_+_99899180 3.82 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr2_-_89597542 3.79 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr1_-_156675368 3.71 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr17_-_39743139 3.71 ENST00000167586.6
KRT14
keratin 14
chr2_+_89890533 3.70 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr12_-_56236711 3.68 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr1_+_27669719 3.66 ENST00000473280.1
SYTL1
synaptotagmin-like 1
chr7_+_22766766 3.63 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr16_-_122619 3.62 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr15_+_41136734 3.59 ENST00000568580.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr12_+_48152774 3.58 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr11_+_394196 3.55 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr16_+_1306060 3.54 ENST00000397534.2
TPSD1
tryptase delta 1
chrX_-_154563889 3.52 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr15_+_41136369 3.50 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr2_+_114163945 3.50 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr16_+_1290725 3.48 ENST00000461509.2
TPSAB1
tryptase alpha/beta 1
chr8_+_105352050 3.47 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr12_-_48152853 3.47 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr15_+_41136263 3.47 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr10_-_4285835 3.46 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr5_-_75919217 3.39 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr7_+_94023873 3.30 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr1_+_201252580 3.23 ENST00000367324.3
ENST00000263946.3
PKP1
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr19_-_44285401 3.22 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_-_53343602 3.20 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr11_-_6341844 3.19 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr1_-_12679171 3.17 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr12_-_56236690 3.16 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr3_+_30648066 3.14 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_+_30647994 3.10 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr16_+_1306093 3.08 ENST00000211076.3
TPSD1
tryptase delta 1
chr1_-_43751276 3.07 ENST00000423420.1
C1orf210
chromosome 1 open reading frame 210
chr10_-_6019552 3.07 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr6_+_44194762 3.05 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_-_87040233 3.05 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr11_-_67141640 3.03 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr15_-_51535208 3.02 ENST00000405913.3
ENST00000559878.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr2_+_120189422 3.02 ENST00000306406.4
TMEM37
transmembrane protein 37
chr13_-_41593425 3.01 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_11178779 2.98 ENST00000438284.2
HRH1
histamine receptor H1
chr18_+_3450161 2.98 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr18_+_61442629 2.96 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_183155373 2.92 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr15_+_89182156 2.90 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr8_+_87111059 2.88 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr14_-_24806588 2.86 ENST00000555591.1
ENST00000554569.1
RP11-934B9.3
RIPK3
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr11_-_65667884 2.86 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr10_-_6019455 2.86 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr5_-_75919253 2.82 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chrX_+_115567767 2.78 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr14_-_107078851 2.77 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr12_+_13349650 2.77 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr11_-_62457371 2.77 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr1_-_43751230 2.76 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr15_+_89181974 2.76 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_-_2908155 2.75 ENST00000571228.1
ENST00000161006.3
PRSS22
protease, serine, 22
chr3_-_87039662 2.75 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr2_+_36923830 2.75 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr19_+_39279838 2.74 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr1_-_113247543 2.72 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr14_-_25103472 2.71 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr15_-_20170354 2.71 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr1_-_45272951 2.68 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr12_-_91573249 2.68 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr19_-_47128294 2.68 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr17_+_7482785 2.67 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr11_-_10590118 2.66 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_+_13349711 2.65 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr12_-_53343633 2.63 ENST00000546826.1
KRT8
keratin 8
chr1_-_153538011 2.62 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr1_+_27719148 2.61 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr10_-_6019984 2.59 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr12_-_91573316 2.58 ENST00000393155.1
DCN
decorin
chr1_+_901847 2.57 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr12_-_91573132 2.57 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr11_+_128563652 2.56 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr15_+_89182178 2.56 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_-_69760409 2.55 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr17_+_59529743 2.55 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr2_+_208104351 2.51 ENST00000440326.1
AC007879.7
AC007879.7
chr11_+_35639735 2.51 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr11_-_65667997 2.51 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr3_+_191046810 2.49 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr14_+_22748980 2.48 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr22_+_22707260 2.48 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr1_+_156095951 2.45 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr19_-_40931891 2.42 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr5_-_149535421 2.41 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr7_-_135433534 2.41 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chrX_-_48901012 2.38 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr3_+_148447887 2.37 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr17_-_19062424 2.36 ENST00000399083.1
AC007952.6
Uncharacterized protein
chr2_+_102618428 2.36 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr13_+_78109884 2.35 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr19_-_36004543 2.33 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr19_+_38794797 2.31 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr11_+_46402297 2.29 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_158656488 2.28 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_-_149095652 2.27 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr10_+_75668916 2.27 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr8_+_104384616 2.26 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr11_-_10590238 2.26 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_-_194090460 2.25 ENST00000428839.1
ENST00000347624.3
LRRC15
leucine rich repeat containing 15
chr16_+_31366536 2.24 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_-_151034734 2.23 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_-_141030943 2.23 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr2_+_90248739 2.18 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chrX_-_129244336 2.18 ENST00000434609.1
ELF4
E74-like factor 4 (ets domain transcription factor)
chr6_-_149806105 2.17 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr17_-_53800217 2.16 ENST00000424486.2
TMEM100
transmembrane protein 100
chr10_+_104155450 2.16 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr14_-_25103388 2.16 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr13_+_78109804 2.15 ENST00000535157.1
SCEL
sciellin
chr1_+_26606608 2.14 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr14_-_91710852 2.14 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr11_-_2950642 2.13 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_+_74405804 2.13 ENST00000287097.5
CD109
CD109 molecule

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
2.1 6.2 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.7 8.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.6 8.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.5 7.5 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
1.4 4.3 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
1.4 237.2 GO:0030449 regulation of complement activation(GO:0030449)
1.4 4.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
1.2 3.7 GO:1902362 melanocyte apoptotic process(GO:1902362)
1.2 10.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.2 6.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.1 10.2 GO:0002159 desmosome assembly(GO:0002159)
1.1 5.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
1.0 7.9 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
1.0 2.9 GO:0042660 positive regulation of cell fate specification(GO:0042660)
1.0 10.7 GO:0001554 luteolysis(GO:0001554)
1.0 1.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.0 2.9 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.9 3.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9 6.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.9 24.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.9 7.4 GO:0072675 osteoclast fusion(GO:0072675)
0.8 30.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.8 8.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.8 4.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.8 4.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.8 2.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.8 3.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.8 15.0 GO:0051546 keratinocyte migration(GO:0051546)
0.7 2.1 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.7 4.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.7 2.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.7 9.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.7 5.4 GO:0007296 vitellogenesis(GO:0007296)
0.7 4.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.7 2.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.6 14.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.6 1.9 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.6 1.9 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.6 3.1 GO:0015862 uridine transport(GO:0015862)
0.6 4.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 2.4 GO:0006218 uridine catabolic process(GO:0006218)
0.6 2.4 GO:0035425 autocrine signaling(GO:0035425)
0.6 2.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.6 7.7 GO:0046449 creatinine metabolic process(GO:0046449)
0.6 4.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.6 9.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.6 122.3 GO:0002377 immunoglobulin production(GO:0002377)
0.6 2.8 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.5 2.2 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.5 2.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.5 1.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 18.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5 1.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.5 5.8 GO:0001866 NK T cell proliferation(GO:0001866)
0.5 1.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.5 1.9 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.5 2.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.5 2.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.5 1.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 1.3 GO:1901656 glycoside transport(GO:1901656)
0.4 1.3 GO:0035607 vacuolar phosphate transport(GO:0007037) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 3.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 2.2 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.4 6.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.4 0.9 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.4 2.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.4 1.3 GO:0051414 response to cortisol(GO:0051414)
0.4 5.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 2.3 GO:0030421 defecation(GO:0030421)
0.4 1.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 1.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.4 1.5 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 1.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 0.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.4 2.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 3.9 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.4 1.4 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 7.0 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.3 4.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 2.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.3 4.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 2.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.3 2.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 1.9 GO:0060005 vestibular reflex(GO:0060005)
0.3 4.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.3 1.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.3 0.9 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.3 1.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 7.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.3 1.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.3 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 5.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 6.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 1.5 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.3 0.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.2 1.9 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 2.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 5.1 GO:0001765 membrane raft assembly(GO:0001765)
0.2 1.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.9 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 0.7 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 2.0 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 0.7 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 2.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.2 3.3 GO:0043589 skin morphogenesis(GO:0043589)
0.2 1.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 2.4 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 3.6 GO:0015886 heme transport(GO:0015886)
0.2 1.5 GO:0038183 bile acid signaling pathway(GO:0038183)
0.2 1.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 1.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 3.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2 0.6 GO:0033590 response to cobalamin(GO:0033590)
0.2 5.4 GO:0032060 bleb assembly(GO:0032060)
0.2 1.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 2.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.5 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 2.2 GO:0046541 saliva secretion(GO:0046541)
0.2 2.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 2.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.2 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 1.1 GO:0015793 glycerol transport(GO:0015793)
0.2 2.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.2 GO:0051607 defense response to virus(GO:0051607)
0.1 4.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.3 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 1.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.9 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.6 GO:0001845 phagolysosome assembly(GO:0001845)
0.1 0.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 2.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 3.7 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 2.2 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 5.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.0 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 2.0 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 2.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.0 GO:0097070 ductus arteriosus closure(GO:0097070)
0.1 0.7 GO:0060326 cell chemotaxis(GO:0060326)
0.1 2.0 GO:0044849 estrous cycle(GO:0044849)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.5 GO:0009615 response to virus(GO:0009615)
0.1 0.5 GO:1904994 regulation of leukocyte tethering or rolling(GO:1903236) regulation of leukocyte adhesion to vascular endothelial cell(GO:1904994)
0.1 1.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 2.9 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.7 GO:0002934 desmosome organization(GO:0002934)
0.1 0.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 1.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.1 GO:0035938 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.7 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.3 GO:1903596 regulation of gap junction assembly(GO:1903596) negative regulation of gap junction assembly(GO:1903597)
0.1 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 2.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 12.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 8.9 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 5.1 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.1 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 12.5 GO:0007586 digestion(GO:0007586)
0.1 3.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0007320 insemination(GO:0007320)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 1.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 5.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.7 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.5 GO:0010842 retina layer formation(GO:0010842)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 1.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 1.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 1.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 1.2 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 1.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 1.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 4.7 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.6 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.2 GO:0006825 copper ion transport(GO:0006825)
0.0 1.5 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.9 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 1.7 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.9 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.6 GO:1904776 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.7 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.9 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.0 GO:0007398 ectoderm development(GO:0007398)
0.0 1.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 2.1 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.5 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.6 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 2.8 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0007588 excretion(GO:0007588)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 1.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 1.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 2.4 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 1.9 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.9 GO:0007631 feeding behavior(GO:0007631)
0.0 1.7 GO:0051225 spindle assembly(GO:0051225)
0.0 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0050954 sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
2.2 24.2 GO:0005610 laminin-5 complex(GO:0005610)
1.7 6.9 GO:0005607 laminin-2 complex(GO:0005607)
1.1 3.3 GO:0005584 collagen type I trimer(GO:0005584)
1.0 4.0 GO:0045160 myosin I complex(GO:0045160)
0.9 2.7 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.9 8.7 GO:0005638 lamin filament(GO:0005638)
0.8 3.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.8 2.3 GO:0097444 spine apparatus(GO:0097444)
0.7 28.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.6 11.6 GO:0071438 invadopodium membrane(GO:0071438)
0.6 3.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.6 6.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 2.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 7.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 103.6 GO:0072562 blood microparticle(GO:0072562)
0.4 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.4 1.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.3 13.3 GO:0030057 desmosome(GO:0030057)
0.3 2.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 7.1 GO:0097342 ripoptosome(GO:0097342)
0.3 4.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 3.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 2.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.3 1.8 GO:0032437 cuticular plate(GO:0032437)
0.2 0.9 GO:0031251 PAN complex(GO:0031251)
0.2 0.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.4 GO:0001652 granular component(GO:0001652)
0.2 0.9 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 2.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 2.4 GO:0070652 HAUS complex(GO:0070652)
0.2 1.6 GO:0030478 actin cap(GO:0030478)
0.2 2.9 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 1.8 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 8.6 GO:0008305 integrin complex(GO:0008305)
0.1 5.5 GO:0031527 filopodium membrane(GO:0031527)
0.1 10.3 GO:0001772 immunological synapse(GO:0001772)
0.1 4.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 1.3 GO:0097413 Lewy body(GO:0097413)
0.1 1.8 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 227.3 GO:0005615 extracellular space(GO:0005615)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 1.8 GO:0090543 Flemming body(GO:0090543)
0.1 2.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 8.2 GO:0015030 Cajal body(GO:0015030)
0.1 14.8 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:1990462 omegasome(GO:1990462)
0.1 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 3.6 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 7.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.2 GO:0031932 TORC2 complex(GO:0031932)
0.1 8.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 8.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 6.5 GO:0030315 T-tubule(GO:0030315)
0.1 2.8 GO:0005901 caveola(GO:0005901)
0.1 3.3 GO:0002102 podosome(GO:0002102)
0.1 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.1 GO:0005861 troponin complex(GO:0005861)
0.1 12.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.5 GO:0010369 chromocenter(GO:0010369)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 5.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 3.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 9.1 GO:0098862 cluster of actin-based cell projections(GO:0098862)
0.0 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 3.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 5.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 6.2 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 6.3 GO:0001726 ruffle(GO:0001726)
0.0 124.0 GO:0005576 extracellular region(GO:0005576)
0.0 4.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.2 GO:0043209 myelin sheath(GO:0043209)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
2.7 8.2 GO:0008859 exoribonuclease II activity(GO:0008859)
1.6 6.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.5 4.5 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.3 345.5 GO:0003823 antigen binding(GO:0003823)
1.2 3.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.1 3.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.1 7.9 GO:1990254 keratin filament binding(GO:1990254)
1.1 7.9 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
1.1 4.3 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
1.0 3.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
1.0 4.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.9 7.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.9 2.6 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.8 2.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.6 1.9 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.6 1.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 1.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 3.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 2.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5 2.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.5 2.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.5 3.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 2.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 2.7 GO:0070026 nitric oxide binding(GO:0070026)
0.4 3.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 7.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 4.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.4 2.9 GO:0042806 fucose binding(GO:0042806)
0.4 4.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 10.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 3.0 GO:0019215 intermediate filament binding(GO:0019215)
0.4 1.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.3 11.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 3.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 2.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 0.9 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.3 5.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 1.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.3 0.9 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 1.4 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 1.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.3 0.8 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 3.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 5.9 GO:0005522 profilin binding(GO:0005522)
0.3 2.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 12.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 1.0 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 1.5 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.3 1.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.3 9.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 2.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 1.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 2.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 3.4 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 4.7 GO:0019841 retinol binding(GO:0019841)
0.2 1.1 GO:0015254 glycerol channel activity(GO:0015254)
0.2 0.7 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 1.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 1.5 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 2.7 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 35.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 2.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 3.5 GO:0004568 chitinase activity(GO:0004568)
0.2 2.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.2 8.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 4.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 5.3 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 26.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 7.5 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.8 GO:1990460 leptin receptor binding(GO:1990460)
0.2 0.8 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 4.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.4 GO:0019863 IgE binding(GO:0019863)
0.1 3.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 5.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 11.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 3.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.0 GO:0019956 chemokine binding(GO:0019956)
0.1 1.5 GO:0071253 connexin binding(GO:0071253)
0.1 1.1 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.0 GO:0070330 aromatase activity(GO:0070330)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 3.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.9 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 24.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 2.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 3.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 3.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.8 GO:0008009 chemokine activity(GO:0008009)
0.0 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.8 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 23.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 6.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 4.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 42.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 3.2 GO:0019838 growth factor binding(GO:0019838)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 8.2 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 4.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.3 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 4.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.3 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 3.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 3.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 4.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 34.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.7 52.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 9.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 6.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 8.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 13.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 5.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 14.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 9.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 12.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 5.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 6.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 4.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 8.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 8.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 8.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 2.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 6.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 22.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 15.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 4.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 20.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 8.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 18.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 7.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 36.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.3 9.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 5.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 9.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 4.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 6.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 16.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 3.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 7.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 5.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 9.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 7.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 7.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 4.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 3.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 7.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 5.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 7.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 5.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 3.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 7.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 3.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 4.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 2.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 7.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 2.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation