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Illumina Body Map 2: averaged replicates

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Results for FOXA1

Z-value: 2.67

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
ENSG00000129514.4 FOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg19_v2_chr14_-_38064198_380642390.691.3e-05Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_26695013 12.01 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 11.83 ENST00000438614.1
VTN
vitronectin
chr1_-_57431679 9.77 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr14_-_94789663 9.39 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr4_-_155533787 9.12 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr17_-_39684550 7.63 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr14_-_38064198 6.54 ENST00000250448.2
FOXA1
forkhead box A1
chr10_+_81370689 6.39 ENST00000372308.3
ENST00000398636.3
ENST00000428376.2
ENST00000372313.5
ENST00000419470.2
ENST00000429958.1
ENST00000439264.1
SFTPA1
surfactant protein A1
chr4_-_72649763 6.19 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr17_-_46035187 6.09 ENST00000300557.2
PRR15L
proline rich 15-like
chr11_-_116663127 5.76 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr8_+_120079478 5.61 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr5_-_41213607 5.55 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr22_+_21128167 5.48 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_+_62186498 5.48 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr3_+_52811596 5.04 ENST00000542827.1
ENST00000273283.2
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr4_+_187148556 4.96 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr3_+_186330712 4.93 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr5_-_41213123 4.92 ENST00000417809.1
C6
complement component 6
chr15_+_69854027 4.87 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr10_-_81320151 4.85 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2
surfactant protein A2
chr10_+_51549498 4.82 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr11_-_102401469 4.55 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_-_89161064 4.29 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr20_-_7921090 4.28 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr12_-_53343602 4.28 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr2_+_7865923 4.25 ENST00000417930.1
AC092580.4
AC092580.4
chr20_+_31595406 4.24 ENST00000170150.3
BPIFB2
BPI fold containing family B, member 2
chr14_-_36988882 4.23 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr3_+_137717571 3.88 ENST00000343735.4
CLDN18
claudin 18
chr21_-_31588365 3.84 ENST00000399899.1
CLDN8
claudin 8
chrX_+_135614293 3.81 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr1_-_27240455 3.80 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr16_-_86542455 3.78 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr4_+_187187098 3.77 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr2_-_89160425 3.70 ENST00000390239.2
IGKJ4
immunoglobulin kappa joining 4
chr12_-_53343633 3.66 ENST00000546826.1
KRT8
keratin 8
chr2_-_69180083 3.65 ENST00000328895.4
GKN2
gastrokine 2
chr3_+_137728842 3.60 ENST00000183605.5
CLDN18
claudin 18
chr19_+_18496957 3.56 ENST00000252809.3
GDF15
growth differentiation factor 15
chr3_-_148939598 3.52 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr12_-_53343560 3.48 ENST00000548998.1
KRT8
keratin 8
chr21_-_31588338 3.48 ENST00000286809.1
CLDN8
claudin 8
chr21_-_43735446 3.47 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr1_+_200011711 3.40 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_-_165424973 3.30 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr2_+_162101247 3.26 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr11_-_124622134 3.25 ENST00000326621.5
VSIG2
V-set and immunoglobulin domain containing 2
chr13_-_86373536 3.20 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr2_-_89160770 3.19 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr2_-_89160117 3.18 ENST00000390238.2
IGKJ5
immunoglobulin kappa joining 5
chr12_-_120765565 3.18 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr12_-_91572278 3.15 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr7_+_134576151 3.11 ENST00000393118.2
CALD1
caldesmon 1
chr2_-_21266935 3.11 ENST00000233242.1
APOB
apolipoprotein B
chr1_+_199996733 2.98 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_+_8924837 2.97 ENST00000173229.2
NTN1
netrin 1
chr3_+_148447887 2.95 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr3_-_148939835 2.94 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr6_+_135502501 2.93 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr7_+_73242490 2.93 ENST00000431918.1
CLDN4
claudin 4
chr1_+_199996702 2.91 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr15_+_96869165 2.91 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_124622083 2.82 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chr9_-_4859260 2.78 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr1_-_177939041 2.74 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr4_+_55095264 2.71 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr10_+_124320156 2.71 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr4_+_187187337 2.69 ENST00000492972.2
F11
coagulation factor XI
chr2_-_69180012 2.68 ENST00000481498.1
GKN2
gastrokine 2
chr1_-_203320617 2.68 ENST00000354955.4
FMOD
fibromodulin
chr12_-_102872317 2.67 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr18_+_56113488 2.65 ENST00000590797.1
RP11-1151B14.3
RP11-1151B14.3
chr6_+_161123270 2.65 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr20_+_31823792 2.63 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr14_-_70263979 2.63 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr9_+_27109133 2.63 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr2_-_104496621 2.62 ENST00000455716.1
AC013727.1
AC013727.1
chr7_-_81399438 2.62 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_+_186692745 2.62 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_-_41715128 2.60 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr4_-_70080449 2.51 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr17_-_48546324 2.49 ENST00000508540.1
CHAD
chondroadherin
chr1_-_111743285 2.46 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr15_-_55541227 2.37 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr6_-_46922659 2.36 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr18_+_66465475 2.32 ENST00000581520.1
CCDC102B
coiled-coil domain containing 102B
chr12_-_89746173 2.31 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chrX_-_15402498 2.28 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr7_-_81399329 2.28 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_48546232 2.27 ENST00000258969.4
CHAD
chondroadherin
chr13_-_46716969 2.21 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_+_17791648 2.17 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_126442563 2.16 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr14_-_36983034 2.15 ENST00000518529.2
SFTA3
surfactant associated 3
chr7_-_81399355 2.13 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_71389281 2.11 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr4_+_55095428 2.09 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr10_+_124320195 2.05 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr12_+_103981044 2.04 ENST00000388887.2
STAB2
stabilin 2
chr2_-_21266816 2.02 ENST00000399256.4
APOB
apolipoprotein B
chr6_-_90025011 2.00 ENST00000402938.3
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr10_-_81708854 2.00 ENST00000372292.3
SFTPD
surfactant protein D
chr6_-_90024967 1.97 ENST00000602399.1
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr12_+_27849378 1.96 ENST00000310791.2
REP15
RAB15 effector protein
chr21_+_17791838 1.94 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr21_+_17443521 1.93 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_71551652 1.92 ENST00000546561.1
TSPAN8
tetraspanin 8
chr19_-_49118067 1.91 ENST00000593772.1
FAM83E
family with sequence similarity 83, member E
chr7_+_134576317 1.90 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr21_+_17792672 1.90 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr3_+_52245458 1.87 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr3_-_145878954 1.86 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_+_142315225 1.86 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr1_+_223101757 1.86 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr9_+_136287444 1.80 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr7_+_80231466 1.78 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_89746264 1.76 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr2_+_88047606 1.74 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr7_-_81399411 1.74 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_-_111119804 1.74 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr12_-_71551868 1.72 ENST00000247829.3
TSPAN8
tetraspanin 8
chr7_-_81399678 1.72 ENST00000412881.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr21_-_40033618 1.72 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr9_-_95186739 1.70 ENST00000375550.4
OMD
osteomodulin
chr7_-_81399287 1.70 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr21_-_43771226 1.70 ENST00000291526.4
TFF2
trefoil factor 2
chr13_+_78109804 1.68 ENST00000535157.1
SCEL
sciellin
chr16_-_68034452 1.68 ENST00000575510.1
DPEP2
dipeptidase 2
chr19_+_18492973 1.68 ENST00000595973.2
GDF15
growth differentiation factor 15
chr3_+_174577070 1.67 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr4_-_74486109 1.66 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_10528560 1.65 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr11_-_108464465 1.64 ENST00000525344.1
EXPH5
exophilin 5
chr11_-_108464321 1.64 ENST00000265843.4
EXPH5
exophilin 5
chr6_-_161085291 1.61 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr5_-_121659052 1.59 ENST00000512105.1
CTD-2544H17.1
CTD-2544H17.1
chr18_+_68002675 1.58 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr1_-_95391315 1.57 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr2_-_182545603 1.55 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr14_+_37126765 1.54 ENST00000402703.2
PAX9
paired box 9
chr17_+_72427477 1.53 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_+_171640291 1.52 ENST00000409885.1
ERICH2
glutamate-rich 2
chr18_+_66465302 1.51 ENST00000360242.5
ENST00000358653.5
CCDC102B
coiled-coil domain containing 102B
chr13_+_78109884 1.46 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr5_-_148758839 1.45 ENST00000261796.3
IL17B
interleukin 17B
chr14_+_38065052 1.44 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr1_-_216596738 1.41 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr3_-_185538849 1.39 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr15_+_59910132 1.38 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_178840157 1.37 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr7_+_116165754 1.37 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_-_81399744 1.36 ENST00000421558.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_71162995 1.35 ENST00000234396.4
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr13_+_76334795 1.32 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr10_+_102891048 1.30 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr21_+_17443434 1.29 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_87804815 1.27 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr2_+_71163051 1.27 ENST00000412314.1
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr18_-_52626622 1.24 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr2_-_158345462 1.23 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr13_+_76334567 1.21 ENST00000321797.8
LMO7
LIM domain 7
chr3_+_142315294 1.19 ENST00000464320.1
PLS1
plastin 1
chr3_+_160394940 1.18 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr12_+_121416437 1.18 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr12_+_121416340 1.17 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr6_-_108145499 1.13 ENST00000369020.3
ENST00000369022.2
SCML4
sex comb on midleg-like 4 (Drosophila)
chr7_-_107443652 1.13 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr14_-_104408032 1.12 ENST00000455348.2
RD3L
retinal degeneration 3-like
chr11_+_844406 1.10 ENST00000397404.1
TSPAN4
tetraspanin 4
chr12_+_121416489 1.08 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr6_+_135502466 1.08 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr2_-_158345341 1.08 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr8_-_133772794 1.06 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr10_-_90751038 1.04 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_-_21806759 1.03 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chrX_+_37865804 1.00 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr17_-_17485731 1.00 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr17_-_39140549 1.00 ENST00000377755.4
KRT40
keratin 40
chr3_+_72201910 0.99 ENST00000469178.1
ENST00000485404.1
LINC00870
long intergenic non-protein coding RNA 870
chr16_-_73178346 0.99 ENST00000358463.2
C16orf47
chromosome 16 open reading frame 47
chr4_+_75174180 0.98 ENST00000413830.1
EPGN
epithelial mitogen
chr4_-_74486347 0.96 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_+_121902511 0.96 ENST00000490131.1
CASR
calcium-sensing receptor
chr4_+_68424434 0.94 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr10_-_23528745 0.91 ENST00000376501.5
C10orf115
chromosome 10 open reading frame 115
chr7_+_134430212 0.91 ENST00000436461.2
CALD1
caldesmon 1
chr7_-_92855762 0.91 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr19_-_48894104 0.90 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr17_+_72426891 0.90 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_-_77325545 0.85 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1
RSBN1L antisense RNA 1
chr5_+_179921430 0.85 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chr6_+_139135648 0.83 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr2_+_204801471 0.83 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr1_+_94798754 0.81 ENST00000418242.1
RP11-148B18.3
RP11-148B18.3
chr4_+_165675197 0.81 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr4_-_186456766 0.80 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr8_-_133772870 0.78 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr2_-_192711968 0.77 ENST00000304141.4
SDPR
serum deprivation response
chr6_+_112375275 0.76 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WISP3
WNT1 inducible signaling pathway protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 14.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
2.2 6.5 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
2.1 10.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.5 4.5 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.2 4.8 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
1.2 5.8 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
1.1 3.4 GO:0035623 renal glucose absorption(GO:0035623)
1.1 9.5 GO:0061113 pancreas morphogenesis(GO:0061113)
1.0 13.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.9 5.5 GO:0010193 response to ozone(GO:0010193)
0.9 7.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.8 4.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.8 5.5 GO:0008218 bioluminescence(GO:0008218)
0.7 7.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.7 2.9 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.7 2.9 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.7 2.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.7 4.8 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.7 11.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.7 2.6 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.6 5.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 3.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.6 11.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 2.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.5 3.2 GO:0060005 vestibular reflex(GO:0060005)
0.5 1.5 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.5 6.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 1.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 1.4 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 3.0 GO:1902896 terminal web assembly(GO:1902896)
0.4 2.6 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 9.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 9.1 GO:0031639 plasminogen activation(GO:0031639)
0.4 6.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 3.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 6.4 GO:0008228 opsonization(GO:0008228)
0.4 4.2 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 2.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 2.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 0.9 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.3 10.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 0.8 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 9.4 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 0.8 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 3.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2 1.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 6.5 GO:0006825 copper ion transport(GO:0006825)
0.2 6.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 4.6 GO:0044849 estrous cycle(GO:0044849)
0.2 4.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 0.7 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 3.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 1.8 GO:0035864 response to potassium ion(GO:0035864)
0.2 2.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.8 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 7.7 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 4.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.7 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 1.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 7.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.4 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 1.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.6 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.9 GO:0060539 diaphragm development(GO:0060539)
0.1 1.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 4.6 GO:0033572 transferrin transport(GO:0033572)
0.1 0.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.4 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 1.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 1.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.8 GO:0060174 limb bud formation(GO:0060174)
0.1 0.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.2 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 3.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 3.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.4 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 4.8 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 2.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.0 1.5 GO:0007635 chemosensory behavior(GO:0007635)
0.0 4.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 3.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.6 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 2.6 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 11.8 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.0 20.2 GO:0005579 membrane attack complex(GO:0005579)
1.3 10.7 GO:1990357 terminal web(GO:1990357)
1.3 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.7 9.1 GO:0005577 fibrinogen complex(GO:0005577)
0.6 5.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.6 21.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 15.5 GO:0042599 lamellar body(GO:0042599)
0.5 1.4 GO:0002139 stereocilia coupling link(GO:0002139)
0.4 5.9 GO:0030478 actin cap(GO:0030478)
0.4 2.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4 3.0 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 5.8 GO:0042627 chylomicron(GO:0042627)
0.2 3.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 3.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 2.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 16.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 13.1 GO:0005902 microvillus(GO:0005902)
0.1 18.0 GO:0072562 blood microparticle(GO:0072562)
0.1 1.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.1 GO:0016342 catenin complex(GO:0016342)
0.1 6.1 GO:0045178 basal part of cell(GO:0045178)
0.1 1.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 6.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 6.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.6 GO:0034358 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.9 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 3.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 8.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 16.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.2 GO:0031526 brush border membrane(GO:0031526)
0.0 4.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 37.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:1902271 D3 vitamins binding(GO:1902271)
1.4 4.3 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
1.4 10.9 GO:0035473 lipase binding(GO:0035473)
1.2 4.8 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
1.0 2.9 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.9 2.6 GO:1904854 proteasome core complex binding(GO:1904854)
0.6 1.9 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5 6.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 5.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.5 1.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5 1.4 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.5 1.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 2.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 10.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 1.0 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 18.5 GO:0042056 chemoattractant activity(GO:0042056)
0.3 4.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 3.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.9 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 3.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 4.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 6.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 3.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 6.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.7 GO:0001855 complement component C4b binding(GO:0001855)
0.2 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 18.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 3.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 11.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.9 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 2.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 10.5 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.2 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 2.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 12.8 GO:0019210 kinase inhibitor activity(GO:0019210)
0.1 8.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 2.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 11.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 6.2 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 3.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 19.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.5 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 7.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 4.4 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 44.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 25.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 17.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 4.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 11.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 9.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 8.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 9.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 5.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 24.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.7 PID IGF1 PATHWAY IGF1 pathway
0.1 2.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 4.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 11.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 13.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 17.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 20.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 10.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 5.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 12.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 4.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 7.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 9.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 2.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 7.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 13.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 4.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 4.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 2.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events