Motif ID: FOXL1

Z-value: 3.212


Transcription factors associated with FOXL1:

Gene SymbolEntrez IDGene Name
FOXL1 ENSG00000176678.4 FOXL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v2_chr16_+_86609939_866099740.038.7e-01Click!


Activity profile for motif FOXL1.

activity profile for motif FOXL1


Sorted Z-values histogram for motif FOXL1

Sorted Z-values for motif FOXL1



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_89310012 9.958 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr2_-_89417335 9.641 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr4_-_71532339 8.502 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532668 7.921 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_100242549 7.869 ENST00000305046.8
ENST00000394887.3
ADH1B

alcohol dehydrogenase 1B (class I), beta polypeptide

chr2_-_89266286 7.855 ENST00000464162.1
IGKV1-6
immunoglobulin kappa variable 1-6
chr2_-_89399845 7.699 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr2_+_90259593 7.482 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr3_+_151531810 7.306 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr7_+_80275953 7.056 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36


CD36 molecule (thrombospondin receptor)


chr2_-_89476644 6.615 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr9_-_95244781 6.296 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN



asporin



chr14_-_107199464 6.288 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr9_+_13446472 6.252 ENST00000428006.2
RP11-536O18.1
RP11-536O18.1
chr2_+_89952792 6.128 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr3_+_151531859 6.093 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr14_-_107049312 6.019 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr14_-_106725723 5.886 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr4_-_71532207 5.870 ENST00000543780.1
ENST00000391614.3
IGJ

immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

chr8_-_86290333 5.781 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1










carbonic anhydrase I










chr2_+_89975669 5.524 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr4_-_71532601 5.252 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_89998789 5.207 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr14_-_106642049 5.129 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr2_+_90198535 5.027 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr14_-_106478603 4.984 ENST00000390596.2
IGHV4-4
immunoglobulin heavy variable 4-4
chr12_+_69742121 4.861 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ


lysozyme


chr5_+_54398463 4.827 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr7_+_80275752 4.791 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_160709055 4.782 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7



SLAM family member 7



chr2_-_89247338 4.764 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr5_+_156607829 4.714 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr14_-_106471723 4.706 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr2_-_89521942 4.549 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr2_-_89292422 4.547 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr22_+_22723969 4.508 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr14_-_106816253 4.471 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr7_+_80255472 4.418 ENST00000428497.1
CD36
CD36 molecule (thrombospondin receptor)
chr13_-_38172863 4.418 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN





periostin, osteoblast specific factor





chr14_-_106692191 4.349 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr14_-_107211459 4.274 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr2_+_89184868 4.245 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr22_+_23243156 4.191 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr5_-_41261540 4.162 ENST00000263413.3
C6
complement component 6
chr14_-_107283278 4.153 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr22_+_23154239 4.143 ENST00000390315.2
IGLV3-10
immunoglobulin lambda variable 3-10
chr2_-_89442621 4.130 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr2_-_89459813 4.121 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr1_+_117297007 4.105 ENST00000369478.3
ENST00000369477.1
CD2

CD2 molecule

chr2_-_151344172 4.074 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr5_-_43043272 3.977 ENST00000314890.3
ANXA2R
annexin A2 receptor
chr2_+_90060377 3.950 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr14_-_106967788 3.923 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr2_-_89568263 3.894 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr2_+_90043607 3.893 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr2_-_89545079 3.841 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr14_-_107013465 3.819 ENST00000390625.2
IGHV3-49
immunoglobulin heavy variable 3-49
chr2_+_189839046 3.788 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chr2_-_89513402 3.779 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr14_-_106791536 3.758 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr2_-_89630186 3.709 ENST00000390264.2
IGKV2-40
immunoglobulin kappa variable 2-40
chr14_-_106586656 3.657 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr3_+_8543533 3.603 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr14_-_106622419 3.553 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr8_-_86253888 3.491 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1


carbonic anhydrase I


chr16_+_32063311 3.480 ENST00000426099.1
AC142381.1
AC142381.1
chr11_-_59633951 3.471 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr3_+_8543393 3.435 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr2_+_114163945 3.428 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr2_-_89161432 3.379 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr17_+_34391625 3.332 ENST00000004921.3
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr3_+_157154578 3.269 ENST00000295927.3
PTX3
pentraxin 3, long
chr16_+_33006369 3.267 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr2_+_90121477 3.233 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr14_-_106610852 3.186 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr16_+_72090053 3.076 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP


haptoglobin


chr16_+_33605231 3.072 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr14_-_106668095 3.065 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr7_+_80267973 3.043 ENST00000394788.3
ENST00000447544.2
CD36

CD36 molecule (thrombospondin receptor)

chr2_+_90024732 3.025 ENST00000390268.2
IGKV2D-26
immunoglobulin kappa variable 2D-26
chr1_-_89736434 2.981 ENST00000370459.3
GBP5
guanylate binding protein 5
chr22_+_23063100 2.965 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr8_-_82395461 2.957 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr1_-_157522180 2.954 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5



Fc receptor-like 5



chr2_+_89999259 2.932 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr11_-_5248294 2.925 ENST00000335295.4
HBB
hemoglobin, beta
chr14_-_106494587 2.924 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr3_+_12392971 2.919 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr2_+_90077680 2.898 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr2_+_90153696 2.887 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr4_-_100212132 2.883 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr14_-_106406090 2.872 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr2_-_89619904 2.846 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr16_+_56995854 2.831 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr16_+_32077386 2.831 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr22_+_40297079 2.772 ENST00000344138.4
ENST00000543252.1
GRAP2

GRB2-related adaptor protein 2

chr14_-_107078851 2.763 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr14_-_107219365 2.742 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr12_+_60083118 2.740 ENST00000261187.4
ENST00000543448.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr14_+_22337014 2.719 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr7_+_142353445 2.704 ENST00000390396.1
TRBV23-1
T cell receptor beta variable 23-1 (non-functional)
chr4_-_155533787 2.682 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr1_-_157670647 2.677 ENST00000368184.3
FCRL3
Fc receptor-like 3
chr7_-_142162390 2.673 ENST00000390371.3
TRBV6-6
T cell receptor beta variable 6-6
chr17_-_64225508 2.663 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_90108504 2.643 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr22_+_22453093 2.626 ENST00000390283.2
IGLV8-61
immunoglobulin lambda variable 8-61
chr11_+_114168085 2.620 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr7_+_134528635 2.618 ENST00000445569.2
CALD1
caldesmon 1
chr15_-_20193370 2.616 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr22_+_23089870 2.606 ENST00000390311.2
IGLV3-16
immunoglobulin lambda variable 3-16
chr2_-_89340242 2.581 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr14_-_106781017 2.508 ENST00000390612.2
IGHV4-28
immunoglobulin heavy variable 4-28
chr22_+_22681656 2.492 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr15_-_80263506 2.487 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_+_32709119 2.470 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr14_-_106963409 2.460 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr10_+_90521163 2.437 ENST00000404459.1
LIPN
lipase, family member N
chr3_+_8543561 2.436 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr4_-_84035868 2.431 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr14_+_22631122 2.404 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr12_-_91572278 2.403 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN



decorin



chr14_-_106926724 2.399 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr6_-_49604545 2.395 ENST00000371175.4
ENST00000229810.7
RHAG

Rh-associated glycoprotein

chr7_-_93520259 2.374 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr3_-_172241250 2.372 ENST00000420541.2
ENST00000241261.2
TNFSF10

tumor necrosis factor (ligand) superfamily, member 10

chr1_+_186265399 2.371 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr7_+_80253387 2.366 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr6_-_131211534 2.361 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_108541608 2.338 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr2_+_201450591 2.331 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr12_+_60058458 2.318 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_-_91573249 2.316 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN


decorin


chr16_+_33629600 2.308 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr17_+_32683456 2.302 ENST00000225844.2
CCL13
chemokine (C-C motif) ligand 13
chr14_-_106573756 2.298 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr2_-_228579305 2.297 ENST00000456524.1
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr9_-_117853297 2.270 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC


tenascin C


chr2_-_188419078 2.256 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr9_+_124103625 2.256 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr1_-_157670528 2.255 ENST00000368186.5
ENST00000496769.1
FCRL3

Fc receptor-like 3

chr12_-_9268819 2.238 ENST00000404455.2
A2M
alpha-2-macroglobulin
chr1_+_207070775 2.229 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24


interleukin 24


chr12_-_91574142 2.212 ENST00000547937.1
DCN
decorin
chr14_-_106845789 2.201 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr1_+_160709076 2.199 ENST00000359331.4
ENST00000495334.1
SLAMF7

SLAM family member 7

chr4_+_90823130 2.197 ENST00000508372.1
MMRN1
multimerin 1
chr6_-_133055896 2.193 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr10_-_5046042 2.185 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr12_-_10541575 2.182 ENST00000540818.1
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr13_+_110958124 2.165 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr4_-_110723134 2.157 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr8_-_16424871 2.153 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr4_-_84035905 2.146 ENST00000311507.4
PLAC8
placenta-specific 8
chr7_-_93520191 2.097 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr8_+_24241969 2.091 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr2_-_89597542 2.079 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr2_+_152214098 2.074 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_145525015 2.073 ENST00000539363.1
ENST00000538811.1
ITGA10

integrin, alpha 10

chr5_+_54320078 2.061 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr7_-_38289173 2.060 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr11_+_60102304 2.056 ENST00000300182.4
MS4A6E
membrane-spanning 4-domains, subfamily A, member 6E
chr10_+_96522361 2.055 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr7_+_142045246 2.026 ENST00000390392.3
TRBV4-2
T cell receptor beta variable 4-2
chr18_+_42260059 2.020 ENST00000426838.4
SETBP1
SET binding protein 1
chr7_-_142181009 2.000 ENST00000390368.2
TRBV6-5
T cell receptor beta variable 6-5
chr16_+_56995762 1.998 ENST00000200676.3
ENST00000379780.2
CETP

cholesteryl ester transfer protein, plasma

chr12_-_10251539 1.995 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr14_+_22309368 1.979 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr2_+_90458201 1.970 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr3_+_108541545 1.952 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr21_-_43735628 1.948 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr1_+_21880560 1.946 ENST00000425315.2
ALPL
alkaline phosphatase, liver/bone/kidney
chr6_-_133084580 1.939 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr11_-_104972158 1.918 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_+_68424434 1.917 ENST00000265404.2
ENST00000396225.1
STAP1

signal transducing adaptor family member 1

chr1_+_57320437 1.916 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr12_-_91573316 1.896 ENST00000393155.1
DCN
decorin
chr8_+_24241789 1.887 ENST00000256412.4
ENST00000538205.1
ADAMDEC1

ADAM-like, decysin 1

chr3_-_148939598 1.881 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr7_+_80267949 1.880 ENST00000482059.2
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_100558953 1.869 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr18_+_61445007 1.860 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr9_+_112810878 1.858 ENST00000434623.2
ENST00000374525.1
AKAP2

A kinase (PRKA) anchor protein 2

chr4_+_156824840 1.816 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr21_-_35016231 1.811 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr4_-_110723194 1.803 ENST00000394635.3
CFI
complement factor I
chr7_-_38339890 1.781 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr4_-_152149033 1.767 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr3_-_165555200 1.763 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr12_+_9980069 1.749 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1


killer cell lectin-like receptor subfamily F, member 1


chr11_-_5255861 1.746 ENST00000380299.3
HBD
hemoglobin, delta
chr12_-_11463353 1.720 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4


proline-rich protein BstNI subfamily 4


chr10_-_14050522 1.719 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr2_-_228582709 1.717 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3



solute carrier family 19 (thiamine transporter), member 3



chr11_+_69924397 1.716 ENST00000355303.5
ANO1
anoctamin 1, calcium activated chloride channel
chr9_-_14180778 1.715 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr15_-_50558223 1.712 ENST00000267845.3
HDC
histidine decarboxylase
chr5_+_170210721 1.709 ENST00000265294.4
ENST00000519385.1
ENST00000519598.1
GABRP


gamma-aminobutyric acid (GABA) A receptor, pi


chr2_-_188419200 1.706 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
2.0 26.6 GO:0060100 regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155)
1.6 4.8 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
1.4 4.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.3 13.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.3 4.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.3 5.1 GO:0006848 pyruvate transport(GO:0006848)
1.3 6.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
1.1 5.6 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.0 4.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.9 10.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 4.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694)
0.8 2.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.8 2.4 GO:0001907 cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.8 4.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727) regulation of cellular response to oxidative stress(GO:1900407) regulation of response to reactive oxygen species(GO:1901031) regulation of response to oxidative stress(GO:1902882)
0.7 2.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7 2.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.7 5.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 0.6 GO:0006545 glycine biosynthetic process(GO:0006545)
0.6 1.9 GO:0071529 cementum mineralization(GO:0071529)
0.6 4.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.6 3.7 GO:0008228 opsonization(GO:0008228)
0.6 5.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.6 1.7 GO:0001692 histamine metabolic process(GO:0001692)
0.6 1.7 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.5 10.9 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.5 1.5 GO:0021555 inhibition of neuroepithelial cell differentiation(GO:0002085) midbrain-hindbrain boundary morphogenesis(GO:0021555) auditory receptor cell fate determination(GO:0042668) regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.5 1.5 GO:0060279 progesterone secretion(GO:0042701) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 3.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 2.9 GO:0030185 nitric oxide transport(GO:0030185)
0.4 4.8 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.4 3.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.4 1.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.2 GO:0072257 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 7.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 20.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 7.7 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.4 1.8 GO:0019695 choline metabolic process(GO:0019695)
0.3 3.8 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.3 1.3 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.3 1.6 GO:0046968 peptide antigen transport(GO:0046968)
0.3 0.9 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.3 0.9 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.3 0.6 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.3 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 2.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 1.2 GO:0070384 Harderian gland development(GO:0070384)
0.3 0.9 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.3 1.4 GO:0001778 plasma membrane repair(GO:0001778)
0.3 0.8 GO:0050779 RNA destabilization(GO:0050779)
0.3 1.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 1.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 6.0 GO:0019835 cytolysis(GO:0019835)
0.3 0.5 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.3 2.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 1.5 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 1.0 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.2 1.0 GO:0051709 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.2 1.0 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.2 3.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 0.7 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 0.9 GO:0006154 adenosine catabolic process(GO:0006154)
0.2 0.9 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.2 1.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.9 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 1.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 1.5 GO:0032099 negative regulation of appetite(GO:0032099)
0.2 1.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 6.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 9.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 1.8 GO:0051917 regulation of fibrinolysis(GO:0051917)
0.2 1.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.2 1.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 1.0 GO:0070254 mucus secretion(GO:0070254)
0.2 0.6 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.2 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 1.4 GO:0010107 potassium ion import(GO:0010107)
0.2 0.7 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.2 GO:0071318 cellular response to ATP(GO:0071318)
0.2 0.8 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.2 0.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 2.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.2 8.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 4.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.8 GO:2000096 positive regulation of non-canonical Wnt signaling pathway(GO:2000052) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.5 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.2 0.9 GO:0010447 response to acidic pH(GO:0010447)
0.2 1.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.8 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.2 0.3 GO:0031000 response to caffeine(GO:0031000)
0.2 4.4 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.4 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 5.3 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.1 0.6 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.4 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.1 3.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.5 GO:0009405 pathogenesis(GO:0009405)
0.1 1.0 GO:0001553 luteinization(GO:0001553)
0.1 1.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.8 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.7 GO:0060438 trachea development(GO:0060438)
0.1 1.1 GO:0071731 response to nitric oxide(GO:0071731)
0.1 1.1 GO:0010842 retina layer formation(GO:0010842)
0.1 11.2 GO:0006968 cellular defense response(GO:0006968)
0.1 0.8 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 3.9 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 1.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:0052805 histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548) imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.1 1.2 GO:0042640 anagen(GO:0042640)
0.1 1.3 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 2.0 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.3 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.1 1.2 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.1 0.7 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.6 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 1.6 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1 0.5 GO:0090343 positive regulation of cell aging(GO:0090343)
0.1 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.4 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 1.6 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 1.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.4 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.1 0.4 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.8 GO:1901661 quinone metabolic process(GO:1901661)
0.1 1.1 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.4 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.1 2.8 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.1 0.2 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409)
0.1 0.6 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.1 0.3 GO:0032848 regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) positive regulation of cell maturation(GO:1903431)
0.1 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 1.0 GO:0042436 tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.1 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.9 GO:0032464 regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
0.1 2.9 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 1.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.1 1.0 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.4 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.1 0.5 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.0 GO:0045730 respiratory burst(GO:0045730)
0.1 0.5 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.1 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 1.2 GO:0002467 germinal center formation(GO:0002467)
0.1 3.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.9 GO:0008037 cell recognition(GO:0008037)
0.1 6.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.7 GO:0046851 negative regulation of tissue remodeling(GO:0034104) negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 7.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.2 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.9 GO:0003407 neural retina development(GO:0003407)
0.1 6.4 GO:0002576 platelet degranulation(GO:0002576)
0.1 8.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 2.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.9 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 1.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.1 GO:0014040 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.0 1.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 5.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.7 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 1.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.3 GO:0048333 mesodermal cell differentiation(GO:0048333)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 1.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.0 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.1 GO:0070206 protein trimerization(GO:0070206)
0.0 0.4 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.6 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 32.8 GO:0006955 immune response(GO:0006955)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.7 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.8 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.8 GO:0070167 regulation of biomineral tissue development(GO:0070167)
0.0 0.6 GO:0021533 cell differentiation in hindbrain(GO:0021533)
0.0 2.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.3 GO:0042981 regulation of apoptotic process(GO:0042981)
0.0 1.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.3 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.5 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.9 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.5 GO:0051209 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283) calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.5 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.3 GO:0042476 odontogenesis(GO:0042476)
0.0 3.8 GO:0006415 translational termination(GO:0006415)
0.0 0.3 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0034465 cellular potassium ion homeostasis(GO:0030007) response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.0 0.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.0 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.6 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.5 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 1.0 GO:0016049 cell growth(GO:0016049)
0.0 0.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.6 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.2 GO:0060322 brain development(GO:0007420) head development(GO:0060322)
0.0 0.1 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0046676 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.3 GO:0051258 protein polymerization(GO:0051258)
0.0 0.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 2.5 GO:0006954 inflammatory response(GO:0006954)
0.0 1.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 1.4 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.1 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.5 GO:0042698 ovulation cycle(GO:0042698)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.1 28.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.9 9.3 GO:0005579 membrane attack complex(GO:0005579)
0.7 10.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 7.6 GO:0005577 fibrinogen complex(GO:0005577)
0.5 1.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 8.8 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 1.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 1.3 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.3 0.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3 6.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 11.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.3 GO:0071438 invadopodium membrane(GO:0071438)
0.2 4.8 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 1.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.5 GO:0042568 insulin-like growth factor binary complex(GO:0042568)
0.2 1.2 GO:0042599 lamellar body(GO:0042599)
0.2 0.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.1 GO:0002080 acrosomal membrane(GO:0002080)
0.2 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 2.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 4.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.5 GO:0030315 T-tubule(GO:0030315)
0.1 2.5 GO:0008091 spectrin(GO:0008091)
0.1 8.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0051233 spindle midzone(GO:0051233)
0.1 4.9 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.4 GO:0000267 obsolete cell fraction(GO:0000267)
0.1 2.9 GO:0005605 basal lamina(GO:0005605)
0.1 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.8 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.1 1.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 65.8 GO:0005615 extracellular space(GO:0005615)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 16.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 18.4 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 5.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 56.9 GO:0005576 extracellular region(GO:0005576)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 3.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.8 GO:0030496 midbody(GO:0030496)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 6.4 GO:0005625 obsolete soluble fraction(GO:0005625)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 1.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 3.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 26.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.3 2.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.4 8.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.4 11.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.3 4.0 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
1.3 5.1 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
1.2 4.8 GO:0017129 triglyceride binding(GO:0017129)
1.0 3.0 GO:0002114 interleukin-33 receptor activity(GO:0002114)
1.0 4.8 GO:0047026 androsterone dehydrogenase (A-specific) activity(GO:0047026)
0.8 4.2 GO:0070052 collagen V binding(GO:0070052)
0.8 7.5 GO:0030492 hemoglobin binding(GO:0030492)
0.7 2.6 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6 42.3 GO:0003823 antigen binding(GO:0003823)
0.6 4.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 2.2 GO:0033265 choline binding(GO:0033265)
0.5 2.7 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 2.1 GO:0042806 fucose binding(GO:0042806)
0.5 1.5 GO:0048184 obsolete follistatin binding(GO:0048184)
0.5 4.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.5 9.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 2.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.5 1.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 2.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.4 3.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.3 GO:0047042 androsterone dehydrogenase (B-specific) activity(GO:0047042)
0.4 13.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 5.1 GO:0003796 lysozyme activity(GO:0003796)
0.4 1.2 GO:0004771 sterol esterase activity(GO:0004771)
0.4 6.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 1.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 1.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.4 1.5 GO:0043398 HLH domain binding(GO:0043398)
0.4 2.3 GO:0045545 syndecan binding(GO:0045545)
0.4 8.8 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.4 1.8 GO:0032052 bile acid binding(GO:0032052)
0.3 3.5 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.3 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.3 1.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 2.9 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 4.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 1.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 21.7 GO:0005518 collagen binding(GO:0005518)
0.3 1.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.3 2.4 GO:0042731 PH domain binding(GO:0042731)
0.3 14.0 GO:0008009 chemokine activity(GO:0008009)
0.3 1.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.3 0.8 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.3 1.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 3.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 3.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.2 0.7 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.2 3.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 2.4 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.2 GO:0031013 troponin I binding(GO:0031013)
0.2 0.9 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.1 GO:0004918 interleukin-8 receptor activity(GO:0004918) C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 2.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 2.1 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.5 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.2 1.2 GO:0004875 complement receptor activity(GO:0004875)
0.2 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 2.8 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 2.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.5 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898) betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.2 0.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 4.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.0 GO:0019863 IgE binding(GO:0019863)
0.1 1.0 GO:0042805 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0019862 IgA binding(GO:0019862)
0.1 1.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 2.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 17.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 6.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.8 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 3.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.8 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.5 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 3.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.2 GO:0051400 BH domain binding(GO:0051400)
0.1 3.3 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.3 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 2.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.1 0.2 GO:0004086 obsolete carbamoyl-phosphate synthase activity(GO:0004086) carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.1 3.3 GO:0019843 rRNA binding(GO:0019843)
0.1 2.0 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 7.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 7.4 GO:0008201 heparin binding(GO:0008201)
0.1 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 4.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 4.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 12.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.8 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 2.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 4.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 7.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 5.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.0 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.2 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 1.6 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 12.7 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 3.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.0 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.6 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 ST_ADRENERGIC Adrenergic Pathway
0.0 1.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.3 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.