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Illumina Body Map 2: averaged replicates

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Results for FOXO3_FOXD2

Z-value: 2.10

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Transcription factors associated with FOXO3_FOXD2

Gene Symbol Gene ID Gene Info
ENSG00000118689.10 FOXO3
ENSG00000186564.5 FOXD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD2hg19_v2_chr1_+_47901689_479016890.336.9e-02Click!
FOXO3hg19_v2_chr6_+_108977520_1089775490.212.6e-01Click!

Activity profile of FOXO3_FOXD2 motif

Sorted Z-values of FOXO3_FOXD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_31497271 9.54 ENST00000520407.1
NRG1
neuregulin 1
chr6_-_159466136 8.91 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr6_-_159466042 8.20 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr22_+_40342819 8.13 ENST00000407075.3
GRAP2
GRB2-related adaptor protein 2
chr7_-_142511084 7.45 ENST00000417977.2
TRBV30
T cell receptor beta variable 30 (gene/pseudogene)
chrX_+_78426469 6.88 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr1_+_84630645 6.22 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_158345462 6.17 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr9_-_37034028 6.17 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr1_+_117297007 6.15 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr13_-_46716969 5.83 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_84630574 5.82 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_164534657 5.69 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_+_147258266 5.68 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr2_-_158345341 5.47 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr1_+_84630367 5.42 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_118083600 5.26 ENST00000524477.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr12_-_92539614 5.21 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr7_+_28725585 5.05 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr17_-_61776522 4.86 ENST00000582055.1
LIMD2
LIM domain containing 2
chr1_+_84630352 4.84 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_42016385 4.82 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr11_+_10476851 4.70 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr4_-_141075330 4.58 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chrX_+_107288280 4.57 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_772901 4.53 ENST00000305108.4
NINJ2
ninjurin 2
chr10_-_99094458 4.45 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr17_-_61777090 4.43 ENST00000578061.1
LIMD2
LIM domain containing 2
chr12_+_6881678 4.18 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr12_-_123187890 4.17 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chrX_+_9431324 4.16 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr17_-_38721711 4.15 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr11_+_117049910 4.12 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr11_-_118095801 4.09 ENST00000356289.5
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr11_-_118095718 4.08 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr6_+_135502501 4.07 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_-_165305086 4.05 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_-_198175495 3.97 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44
ankyrin repeat domain 44
chr4_+_74606223 3.90 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr7_+_106809406 3.86 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr20_-_50179368 3.85 ENST00000609943.1
ENST00000609507.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_115642293 3.80 ENST00000448680.1
RP4-666F24.3
RP4-666F24.3
chr5_+_176853702 3.79 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr5_+_40841410 3.78 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr10_+_99079008 3.74 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr7_-_37026108 3.74 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr5_+_137673200 3.72 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr12_-_53074182 3.70 ENST00000252244.3
KRT1
keratin 1
chr3_-_71294304 3.69 ENST00000498215.1
FOXP1
forkhead box P1
chr7_-_99698338 3.69 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr15_-_34630234 3.62 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_136875712 3.52 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr5_+_176853669 3.51 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr15_-_34629922 3.50 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr14_+_22356029 3.40 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr1_+_207669613 3.37 ENST00000367049.4
ENST00000529814.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr1_-_207095212 3.36 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr7_-_115608304 3.35 ENST00000457268.1
TFEC
transcription factor EC
chr14_-_23288930 3.33 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_-_71632894 3.28 ENST00000493089.1
FOXP1
forkhead box P1
chr13_-_99910673 3.26 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr1_+_207669573 3.25 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr17_-_29641104 3.24 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr7_+_129906660 3.23 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr18_-_53070913 3.23 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr1_-_26701003 3.23 ENST00000455900.1
ZNF683
zinc finger protein 683
chr5_+_133859996 3.21 ENST00000512386.1
PHF15
jade family PHD finger 2
chr5_+_40841276 3.19 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr14_+_56584414 3.18 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr21_+_39628852 3.15 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_31550192 3.14 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr17_-_29641084 3.14 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr12_-_123201337 3.12 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr15_+_81589254 3.09 ENST00000394652.2
IL16
interleukin 16
chr3_-_117716418 3.09 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr15_-_40600111 3.08 ENST00000543785.2
ENST00000260402.3
PLCB2
phospholipase C, beta 2
chr8_+_31496809 3.08 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr10_-_73848086 3.05 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr18_+_3449330 3.04 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_207095324 3.03 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr11_+_60163918 3.01 ENST00000526375.1
ENST00000531783.1
ENST00000395001.1
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chrX_+_107288197 3.00 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr13_-_99910620 2.98 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr6_-_42418999 2.97 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr9_-_20382446 2.97 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_-_116714564 2.97 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr7_-_105332084 2.97 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr5_+_169064245 2.94 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr18_-_2982869 2.93 ENST00000584915.1
LPIN2
lipin 2
chr11_+_62186498 2.86 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr10_+_51549498 2.86 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr5_-_137674000 2.83 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr21_+_39668478 2.82 ENST00000398927.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_69180083 2.82 ENST00000328895.4
GKN2
gastrokine 2
chr14_+_56585048 2.79 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chrX_+_135730373 2.78 ENST00000370628.2
CD40LG
CD40 ligand
chr1_+_158815588 2.78 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chrX_+_135730297 2.76 ENST00000370629.2
CD40LG
CD40 ligand
chr15_+_81475047 2.74 ENST00000559388.1
IL16
interleukin 16
chr19_-_47734448 2.73 ENST00000439096.2
BBC3
BCL2 binding component 3
chr12_+_93096619 2.73 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chrX_+_107288239 2.71 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr15_-_40600026 2.71 ENST00000456256.2
ENST00000557821.1
PLCB2
phospholipase C, beta 2
chr14_-_36988882 2.71 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr21_+_39668831 2.69 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_-_71179988 2.69 ENST00000491238.1
FOXP1
forkhead box P1
chr5_-_146435572 2.67 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr22_+_40322595 2.67 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr16_+_57680811 2.67 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr7_-_115670792 2.67 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr2_+_163175394 2.65 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr16_+_57680840 2.62 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56
G protein-coupled receptor 56
chrX_-_19688475 2.59 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_1418972 2.58 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr2_+_58655520 2.56 ENST00000455219.3
ENST00000449448.2
AC007092.1
long intergenic non-protein coding RNA 1122
chr5_-_146435694 2.54 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_+_160765919 2.54 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
LY9
lymphocyte antigen 9
chr12_-_49504449 2.53 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chrX_-_54824673 2.53 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr5_+_137673945 2.52 ENST00000513056.1
ENST00000511276.1
FAM53C
family with sequence similarity 53, member C
chr1_+_84629976 2.47 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_133451254 2.46 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr1_+_84630053 2.45 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr16_+_86229728 2.43 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr7_+_80804824 2.43 ENST00000431501.1
AC005008.2
Uncharacterized protein
chr14_+_22446680 2.42 ENST00000390443.3
TRAV8-6
T cell receptor alpha variable 8-6
chr2_+_109223595 2.42 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_-_37934466 2.42 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr9_-_3525968 2.41 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr9_-_98269699 2.39 ENST00000429896.2
PTCH1
patched 1
chr1_+_174933899 2.38 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr5_+_78532003 2.36 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_+_150122034 2.35 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_+_160765884 2.34 ENST00000392203.4
LY9
lymphocyte antigen 9
chr2_-_69180012 2.33 ENST00000481498.1
GKN2
gastrokine 2
chr2_+_204732666 2.32 ENST00000295854.6
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr21_+_39628780 2.32 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_+_37639302 2.32 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr2_+_113885138 2.31 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr1_+_160765860 2.31 ENST00000368037.5
LY9
lymphocyte antigen 9
chr2_+_149402989 2.31 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_-_71114066 2.31 ENST00000485326.2
FOXP1
forkhead box P1
chr2_+_204801471 2.30 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr6_-_89927151 2.30 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr14_+_22180536 2.30 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr3_+_108541545 2.29 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr22_-_31688381 2.28 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr7_+_50348268 2.28 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr17_+_65373531 2.27 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_-_160472952 2.27 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr16_+_30484021 2.27 ENST00000358164.5
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr5_-_146435501 2.27 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_+_40862501 2.26 ENST00000539317.1
SMAP2
small ArfGAP2
chr14_-_36983034 2.25 ENST00000518529.2
SFTA3
surfactant associated 3
chr9_-_5084580 2.24 ENST00000601793.1
AL161450.1
Uncharacterized protein
chr14_+_22670455 2.24 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr9_-_98269481 2.23 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr6_+_135502466 2.22 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr17_-_46657473 2.21 ENST00000332503.5
HOXB4
homeobox B4
chr22_+_40322623 2.21 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr8_+_24151553 2.19 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr2_-_145188137 2.18 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_150966902 2.17 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr2_+_7865923 2.16 ENST00000417930.1
AC092580.4
AC092580.4
chr7_+_139529085 2.16 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr16_+_30483962 2.14 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr13_-_67802549 2.14 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr14_-_91526922 2.13 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr7_+_139528952 2.12 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr7_-_115670804 2.10 ENST00000320239.7
TFEC
transcription factor EC
chr17_+_65374075 2.10 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_+_204732487 2.08 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr12_-_122018114 2.08 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr7_-_140624499 2.08 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr7_-_121944491 2.08 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr22_-_31688431 2.08 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr19_-_6057282 2.07 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr4_-_123542224 2.07 ENST00000264497.3
IL21
interleukin 21
chr11_+_117049445 2.07 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr1_+_86934526 2.06 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr7_+_18536090 2.05 ENST00000441986.1
HDAC9
histone deacetylase 9
chr7_+_77469439 2.05 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr16_+_4666475 2.03 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_-_114414316 2.03 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_+_13906250 2.03 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr19_+_1205740 2.01 ENST00000326873.7
STK11
serine/threonine kinase 11
chr13_-_46756351 2.00 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_+_58755184 1.98 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr1_+_207277590 1.98 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr8_-_133772870 1.98 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr14_+_22891362 1.97 ENST00000390469.2
TRDV2
T cell receptor delta variable 2
chr21_-_16031122 1.97 ENST00000400562.1
AF165138.7
Protein LOC388813
chr7_-_5463175 1.97 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr12_+_96588279 1.96 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_-_130536774 1.96 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr16_+_53469525 1.95 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr2_-_175260368 1.95 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr13_-_31038370 1.95 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr5_-_169725231 1.94 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_139529040 1.94 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 28.1 GO:0097338 response to clozapine(GO:0097338)
2.7 8.2 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
2.7 8.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
2.2 13.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
1.6 8.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.6 6.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.5 7.5 GO:0010157 response to chlorate(GO:0010157)
1.5 4.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
1.4 4.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
1.3 12.6 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
1.1 4.4 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.1 6.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
1.0 2.9 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.9 5.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.9 4.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.9 6.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.8 2.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.8 6.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.7 3.7 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.7 2.2 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.7 3.6 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.7 4.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.7 4.8 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.7 4.7 GO:0006196 AMP catabolic process(GO:0006196)
0.6 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 3.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.6 3.0 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 2.4 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.5 2.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.5 4.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 11.1 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.5 0.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.5 4.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5 7.7 GO:0033227 dsRNA transport(GO:0033227)
0.5 1.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.5 1.5 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.5 3.0 GO:0021993 initiation of neural tube closure(GO:0021993)
0.5 2.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.5 1.9 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.5 1.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.5 2.4 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.5 1.4 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.5 2.4 GO:1904580 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.5 4.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 3.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 1.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.3 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 2.6 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.4 2.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 10.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 1.2 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.4 5.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 5.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 1.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.4 3.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 3.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 1.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 4.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 2.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.4 1.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.4 2.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.4 1.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 4.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 5.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3 4.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 3.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.7 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.3 1.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 7.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 1.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 1.6 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.3 1.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.3 4.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 1.2 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 3.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 1.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.3 2.9 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-4 production(GO:0032713)
0.3 3.4 GO:0021759 globus pallidus development(GO:0021759)
0.3 6.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.4 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 6.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.3 2.2 GO:0048539 bone marrow development(GO:0048539)
0.3 1.4 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 1.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3 1.4 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.3 0.8 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.3 7.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 8.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.3 1.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 0.8 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 0.8 GO:0007518 myoblast fate determination(GO:0007518)
0.3 1.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.3 2.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 1.0 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 1.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 2.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.0 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.2 3.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 0.7 GO:0043132 NAD transport(GO:0043132)
0.2 2.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 5.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 0.5 GO:0021550 medulla oblongata development(GO:0021550)
0.2 2.8 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.2 0.9 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 0.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.7 GO:0021764 amygdala development(GO:0021764)
0.2 5.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 1.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 1.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 5.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.6 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 0.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 1.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 2.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 2.0 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 0.8 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.2 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 4.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 3.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.0 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 2.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 1.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 3.0 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 0.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 1.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.2 GO:0070417 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) cellular response to cold(GO:0070417)
0.2 0.3 GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.2 0.9 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 3.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 2.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 2.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.7 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 0.8 GO:0051029 rRNA transport(GO:0051029)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 2.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.3 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 1.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.2 2.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 0.7 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 2.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 6.9 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 2.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.7 GO:0060460 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.9 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 2.1 GO:0051451 myoblast migration(GO:0051451)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 4.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 6.3 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.0 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 2.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 7.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.6 GO:0001878 response to yeast(GO:0001878)
0.1 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.0 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.5 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 2.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 4.0 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.7 GO:0001555 oocyte growth(GO:0001555)
0.1 4.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 1.1 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 1.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.5 GO:0021603 cranial nerve formation(GO:0021603)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 13.4 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.3 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 2.1 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.4 GO:0051572 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)
0.1 1.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 2.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 2.1 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.1 0.9 GO:0034214 protein hexamerization(GO:0034214)
0.1 2.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.1 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.3 GO:1904502 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 3.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 0.5 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.9 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 5.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 3.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.7 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.7 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 8.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.9 GO:0035878 nail development(GO:0035878)
0.1 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 2.8 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.9 GO:0016577 histone demethylation(GO:0016577)
0.1 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 1.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.7 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 1.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.9 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 3.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.3 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) negative regulation of dendritic spine maintenance(GO:1902951) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 3.9 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.4 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.4 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0070459 negative regulation of luteinizing hormone secretion(GO:0033685) prolactin secretion(GO:0070459)
0.0 2.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 4.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.9 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 1.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 4.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.9 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 2.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 1.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.2 GO:0071034 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 2.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 4.8 GO:0016573 histone acetylation(GO:0016573)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 1.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 2.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 6.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.3 GO:0007602 phototransduction(GO:0007602)
0.0 2.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 3.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 13.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.6 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.4 GO:0043217 myelin maintenance(GO:0043217)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.3 GO:0007140 male meiosis(GO:0007140)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.8 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 1.5 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.6 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.0 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.3 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.6 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 1.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 2.6 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.3 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 2.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 3.8 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.0 1.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 2.4 GO:0007338 single fertilization(GO:0007338)
0.0 0.6 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.3 GO:0033189 response to vitamin A(GO:0033189)
0.0 1.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.4 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 28.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.8 7.5 GO:0044294 dendritic growth cone(GO:0044294)
0.8 3.9 GO:0036398 TCR signalosome(GO:0036398)
0.8 2.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.6 1.9 GO:1902636 kinociliary basal body(GO:1902636)
0.5 2.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5 5.9 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.5 4.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 1.5 GO:0005667 transcription factor complex(GO:0005667)
0.5 1.9 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.5 4.7 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 1.9 GO:0031251 PAN complex(GO:0031251)
0.4 1.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 1.9 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 3.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 1.5 GO:0070701 mucus layer(GO:0070701)
0.3 4.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 1.1 GO:0042585 germinal vesicle(GO:0042585)
0.2 13.0 GO:0030673 axolemma(GO:0030673)
0.2 7.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 9.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.8 GO:0035976 AP1 complex(GO:0035976)
0.2 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 3.7 GO:0042555 MCM complex(GO:0042555)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 3.9 GO:0045178 basal part of cell(GO:0045178)
0.2 2.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.0 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 3.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.2 1.7 GO:0001940 male pronucleus(GO:0001940)
0.2 2.6 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 3.0 GO:0042588 zymogen granule(GO:0042588)
0.1 2.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 4.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.8 GO:0044279 growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 1.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0071565 nBAF complex(GO:0071565)
0.1 3.3 GO:0042599 lamellar body(GO:0042599)
0.1 1.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.5 GO:0033269 internode region of axon(GO:0033269)
0.1 6.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 17.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 7.2 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.7 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.9 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 4.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 10.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 17.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.4 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 4.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 2.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.3 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 3.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0001741 XY body(GO:0001741)
0.1 4.4 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.0 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 11.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 18.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 3.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.6 GO:0070938 contractile ring(GO:0070938)
0.0 5.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.6 GO:0097542 ciliary tip(GO:0097542)
0.0 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 4.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 23.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0032059 bleb(GO:0032059)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 11.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 5.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 12.7 GO:0005769 early endosome(GO:0005769)
0.0 2.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
2.4 7.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.8 5.5 GO:0005174 CD40 receptor binding(GO:0005174)
1.6 4.8 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
1.6 6.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.5 4.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.4 4.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.3 7.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.2 28.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.1 7.5 GO:0005119 smoothened binding(GO:0005119)
1.1 12.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.9 3.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 2.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.6 8.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 1.9 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.6 4.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.6 9.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.6 1.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 8.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 4.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 1.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.5 3.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 5.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 1.9 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.5 3.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.5 4.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 1.4 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.4 3.0 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.4 1.7 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.4 2.9 GO:0042608 T cell receptor binding(GO:0042608)
0.4 4.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 1.9 GO:0002046 opsin binding(GO:0002046)
0.4 3.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 1.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4 8.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.0 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 1.7 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.3 4.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 3.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 8.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 2.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 1.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3 4.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 4.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.3 1.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 1.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.3 9.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.5 GO:0030492 hemoglobin binding(GO:0030492)
0.3 5.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 2.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 6.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.7 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 1.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 2.6 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.8 GO:0035276 ethanol binding(GO:0035276)
0.2 1.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 2.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 3.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 5.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 9.7 GO:0042287 MHC protein binding(GO:0042287)
0.2 3.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 1.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 0.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 3.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 4.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 0.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 0.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 1.4 GO:0071253 connexin binding(GO:0071253)
0.2 3.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 3.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 4.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 4.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 1.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 15.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 3.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 7.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 13.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.7 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 7.4 GO:0070888 E-box binding(GO:0070888)
0.1 5.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 2.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 1.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 2.9 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:1902444 riboflavin binding(GO:1902444)
0.1 3.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 3.2 GO:0016805 dipeptidase activity(GO:0016805)
0.1 5.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.2 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 2.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 5.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 3.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 4.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 9.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 2.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.9 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 1.9 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 2.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 4.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0042835 BRE binding(GO:0042835)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.5 GO:0016015 morphogen activity(GO:0016015)
0.0 1.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 5.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 4.7 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 3.1 GO:0042393 histone binding(GO:0042393)
0.0 6.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 5.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 10.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 12.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 7.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 2.0 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0032934 sterol binding(GO:0032934)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.9 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.2 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 29.4 PID IL3 PATHWAY IL3-mediated signaling events
0.3 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.3 17.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 21.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 10.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 14.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 4.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 8.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 1.7 PID CD40 PATHWAY CD40/CD40L signaling
0.2 11.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 14.3 PID ATR PATHWAY ATR signaling pathway
0.2 14.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 9.0 PID MYC PATHWAY C-MYC pathway
0.2 10.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 1.6 PID FOXO PATHWAY FoxO family signaling
0.1 6.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 7.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 3.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 14.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 16.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 11.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 6.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 16.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 11.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 4.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 6.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 9.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.8 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 5.3 PID P73PATHWAY p73 transcription factor network
0.1 1.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 4.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 28.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 3.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 7.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 12.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 10.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 6.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 4.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.3 16.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 24.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 6.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 24.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 4.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 4.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 2.4 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.2 3.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 4.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 9.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 8.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 5.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 7.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 4.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 5.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 6.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 4.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 8.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 6.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 5.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 4.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 4.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 2.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 3.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 3.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 6.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 9.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.1 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 12.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 7.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 17.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.3 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.1 0.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 9.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 5.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 5.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)