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Illumina Body Map 2: averaged replicates

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Results for FOXO4

Z-value: 2.00

Motif logo

Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
ENSG00000184481.12 FOXO4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO4hg19_v2_chrX_+_70316005_703160470.202.8e-01Click!

Activity profile of FOXO4 motif

Sorted Z-values of FOXO4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_105627735 4.88 ENST00000254765.3
POPDC3
popeye domain containing 3
chr12_-_111358372 4.34 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr7_-_95225768 4.25 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr10_+_123923105 4.08 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr10_-_4285835 3.98 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr10_-_4285923 3.76 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr11_+_113930955 3.40 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr10_-_13570533 3.32 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr10_+_123923205 3.31 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr4_-_100242549 3.20 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr4_-_186696425 3.19 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_32964258 3.18 ENST00000556638.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_86934526 3.18 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr10_+_123922941 3.15 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr6_+_97010424 3.13 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5
four and a half LIM domains 5
chr4_-_152149033 3.09 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr3_+_148447887 3.05 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr5_+_137203465 2.99 ENST00000239926.4
MYOT
myotilin
chr5_+_137203557 2.87 ENST00000515645.1
MYOT
myotilin
chr5_+_137203541 2.86 ENST00000421631.2
MYOT
myotilin
chr16_+_6069072 2.77 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_6069586 2.76 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_+_49984894 2.76 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22
chromosome 8 open reading frame 22
chr9_+_27109440 2.74 ENST00000519080.1
TEK
TEK tyrosine kinase, endothelial
chr12_+_53491220 2.66 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr17_+_72426891 2.57 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_33474826 2.51 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_33474860 2.46 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_8924837 2.46 ENST00000173229.2
NTN1
netrin 1
chr9_+_27109392 2.45 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr7_+_134551583 2.44 ENST00000435928.1
CALD1
caldesmon 1
chr2_+_173955327 2.33 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr3_-_52868931 2.32 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr12_+_54378923 2.31 ENST00000303460.4
HOXC10
homeobox C10
chr6_+_62284008 2.27 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr2_-_71454185 2.26 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_+_54378849 2.23 ENST00000515593.1
HOXC10
homeobox C10
chr4_+_124320665 2.23 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chrX_-_38080077 2.18 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr8_-_6420565 2.18 ENST00000338312.6
ANGPT2
angiopoietin 2
chr12_-_71031185 2.15 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_+_187461442 2.11 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr4_-_186696561 2.11 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr11_-_119247004 2.07 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr5_-_59481406 2.07 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_7580103 2.04 ENST00000596712.1
ZNF358
zinc finger protein 358
chr6_-_46889694 2.03 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr4_-_186696515 2.02 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_183731882 2.00 ENST00000295113.4
FRZB
frizzled-related protein
chr12_-_102872317 1.99 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_+_159570722 1.95 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr17_+_72427477 1.94 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_52869205 1.92 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr8_-_6420777 1.90 ENST00000415216.1
ANGPT2
angiopoietin 2
chr9_+_27109133 1.89 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr7_-_134832752 1.88 ENST00000452718.1
AC083862.1
Uncharacterized protein
chr17_-_67138015 1.84 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr7_+_134832808 1.81 ENST00000275767.3
TMEM140
transmembrane protein 140
chr17_-_67057114 1.79 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr18_+_32073253 1.79 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr19_+_13134772 1.75 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_8075693 1.71 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr8_-_6420930 1.71 ENST00000325203.5
ANGPT2
angiopoietin 2
chr18_-_21852143 1.69 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr10_-_118032697 1.67 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr14_-_61124977 1.65 ENST00000554986.1
SIX1
SIX homeobox 1
chr7_+_55177416 1.64 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr10_+_86184676 1.63 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr9_-_95186739 1.63 ENST00000375550.4
OMD
osteomodulin
chr17_-_67057047 1.63 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_-_57045228 1.61 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_185826855 1.59 ENST00000306376.5
ETV5
ets variant 5
chr20_+_44035200 1.57 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_94577074 1.56 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr4_-_186697044 1.55 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr3_+_132316081 1.53 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr8_-_13134045 1.53 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr5_-_10308125 1.50 ENST00000296658.3
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr1_-_12679171 1.49 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr19_+_859654 1.48 ENST00000592860.1
CFD
complement factor D (adipsin)
chr1_+_200011711 1.47 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr3_-_58522880 1.47 ENST00000474098.1
ACOX2
acyl-CoA oxidase 2, branched chain
chr1_-_115238207 1.46 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr10_-_37891859 1.46 ENST00000544824.1
MTRNR2L7
MT-RNR2-like 7
chr13_-_51101468 1.45 ENST00000428276.1
RP11-175B12.2
RP11-175B12.2
chr2_+_233527443 1.43 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr18_-_68004529 1.40 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr6_-_127780510 1.40 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr12_-_71031220 1.39 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr19_+_859425 1.37 ENST00000327726.6
CFD
complement factor D (adipsin)
chr9_+_5510492 1.37 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr13_-_40924439 1.35 ENST00000400432.3
RP11-172E9.2
RP11-172E9.2
chr5_-_59064458 1.35 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_37723420 1.32 ENST00000476620.1
EPDR1
ependymin related 1
chr18_+_28898052 1.31 ENST00000257192.4
DSG1
desmoglein 1
chr1_-_182360498 1.30 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr9_+_5510558 1.27 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr3_+_138068051 1.27 ENST00000474559.1
MRAS
muscle RAS oncogene homolog
chr9_+_706842 1.25 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr3_+_28390637 1.25 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr11_-_114466471 1.25 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr11_-_89224299 1.25 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NOX4
NADPH oxidase 4
chr17_-_17875688 1.24 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr9_-_140444814 1.23 ENST00000277531.4
PNPLA7
patatin-like phospholipase domain containing 7
chr3_-_71777824 1.22 ENST00000469524.1
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr10_-_118032979 1.22 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr9_-_140444867 1.22 ENST00000406427.1
PNPLA7
patatin-like phospholipase domain containing 7
chr8_-_6420759 1.20 ENST00000523120.1
ANGPT2
angiopoietin 2
chr11_-_89224139 1.16 ENST00000413594.2
NOX4
NADPH oxidase 4
chr2_+_170683979 1.15 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr9_-_13175823 1.14 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr19_-_7293942 1.14 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr11_-_89223883 1.14 ENST00000528341.1
NOX4
NADPH oxidase 4
chr5_-_42811986 1.14 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr10_-_61900762 1.13 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_182360918 1.13 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr22_+_44427230 1.12 ENST00000444029.1
PARVB
parvin, beta
chr11_-_114466477 1.09 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr18_+_6834472 1.08 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr1_+_145525015 1.07 ENST00000539363.1
ENST00000538811.1
ITGA10
integrin, alpha 10
chr2_+_170683942 1.06 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr6_+_108882069 1.06 ENST00000406360.1
FOXO3
forkhead box O3
chr2_+_135809835 1.06 ENST00000264158.8
ENST00000539493.1
ENST00000442034.1
ENST00000425393.1
RAB3GAP1
RAB3 GTPase activating protein subunit 1 (catalytic)
chr1_-_234667504 1.06 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr1_+_63989004 1.06 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr10_-_90751038 1.05 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_-_10251539 1.04 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr2_+_182850551 1.04 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr17_-_1418972 1.03 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr11_+_77532155 1.03 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC
adipogenesis associated, Mth938 domain containing
chr8_-_123793048 1.02 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr9_-_86432547 1.02 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr5_-_42812143 1.02 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr7_-_27702455 1.02 ENST00000265395.2
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr10_+_75668916 1.01 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr14_+_56127989 1.01 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr2_-_100925967 1.01 ENST00000409647.1
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr11_+_112832090 1.01 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr5_-_58571935 1.00 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_31661000 0.99 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr2_+_58134756 0.99 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2
chr19_-_50380536 0.98 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr1_+_47533160 0.97 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr19_+_18111927 0.97 ENST00000379656.3
ARRDC2
arrestin domain containing 2
chr12_-_7596735 0.95 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr8_-_62602327 0.94 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr2_-_23747214 0.94 ENST00000430988.1
AC011239.1
Uncharacterized protein
chr15_+_63188009 0.93 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr19_+_50380917 0.93 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr17_-_8263538 0.91 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr19_-_42916499 0.91 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr20_-_62582475 0.89 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr3_-_145940126 0.89 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr11_+_77532233 0.87 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr3_-_134092561 0.87 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr15_-_52971544 0.85 ENST00000566768.1
ENST00000561543.1
FAM214A
family with sequence similarity 214, member A
chr12_-_10251603 0.85 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr6_+_72596604 0.84 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_86422523 0.83 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr3_-_185826718 0.83 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr16_+_84801852 0.83 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr7_+_120628731 0.82 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr16_+_14980632 0.82 ENST00000565655.1
NOMO1
NODAL modulator 1
chr3_+_121289551 0.81 ENST00000334384.3
ARGFX
arginine-fifty homeobox
chr3_+_112930387 0.80 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr2_+_65283529 0.79 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
CEP68
centrosomal protein 68kDa
chr11_+_34999328 0.79 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr15_+_86805875 0.79 ENST00000389298.3
AGBL1
ATP/GTP binding protein-like 1
chr6_+_123110465 0.79 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr5_+_98104978 0.77 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chr4_-_186696636 0.77 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr16_-_28857677 0.77 ENST00000313511.3
TUFM
Tu translation elongation factor, mitochondrial
chr3_+_173302222 0.77 ENST00000361589.4
NLGN1
neuroligin 1
chr4_-_140223614 0.75 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_+_24439148 0.75 ENST00000543805.1
ENST00000534993.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr2_-_225434538 0.75 ENST00000409096.1
CUL3
cullin 3
chr2_-_166060382 0.74 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr15_-_31283618 0.74 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr1_+_214163033 0.73 ENST00000607425.1
PROX1
prospero homeobox 1
chr10_+_111985837 0.73 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr10_-_62332357 0.72 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_+_67410832 0.72 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_168418553 0.72 ENST00000354419.2
ENST00000351261.3
KIF25
kinesin family member 25
chr3_+_124223586 0.72 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr2_+_157292859 0.71 ENST00000438166.2
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr19_-_29704448 0.71 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr6_+_126277842 0.71 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr3_+_99536663 0.71 ENST00000421999.2
ENST00000463526.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chr1_-_159684371 0.71 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
CRP
C-reactive protein, pentraxin-related
chr1_-_157811588 0.70 ENST00000368174.4
CD5L
CD5 molecule-like
chr18_+_77160282 0.70 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr7_+_113091127 0.69 ENST00000433518.1
TSRM
Uncharacterized protein; Zinc finger domain-related protein TSRM
chr12_-_772901 0.68 ENST00000305108.4
NINJ2
ninjurin 2
chr12_-_109219937 0.68 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr15_-_55657428 0.68 ENST00000568543.1
CCPG1
cell cycle progression 1
chr18_+_31185530 0.68 ENST00000586327.1
ASXL3
additional sex combs like 3 (Drosophila)
chr4_-_80994619 0.67 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr8_+_125860939 0.66 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr2_+_157292933 0.66 ENST00000540309.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_-_115872142 0.66 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.8 3.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.6 5.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6 2.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.6 2.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.5 3.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 2.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 4.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 1.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 1.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.4 1.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.4 2.0 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4 4.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 2.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 1.1 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3 3.9 GO:0031017 exocrine pancreas development(GO:0031017)
0.3 1.9 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 4.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.3 1.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.3 2.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 5.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.7 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 0.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.7 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 9.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 2.0 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.2 0.8 GO:0098923 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 3.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.7 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.5 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.0 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 1.0 GO:0006574 valine catabolic process(GO:0006574)
0.2 3.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 0.7 GO:0019417 sulfur oxidation(GO:0019417)
0.2 3.2 GO:0006069 ethanol oxidation(GO:0006069)
0.2 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.7 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.6 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.7 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) lung vasculature development(GO:0060426) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 2.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 4.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.5 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 2.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.9 GO:0044211 CTP salvage(GO:0044211)
0.1 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.6 GO:0070417 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) cellular response to cold(GO:0070417)
0.1 0.7 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 1.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 3.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.5 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.6 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.5 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.9 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.3 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 2.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.2 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 2.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 5.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 2.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0035799 ureter maturation(GO:0035799)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.7 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 10.2 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 2.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 5.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.6 GO:1901998 toxin transport(GO:1901998)
0.0 2.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 1.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.8 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 3.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.5 GO:0060004 reflex(GO:0060004)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.2 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 8.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.0 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 4.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 4.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 1.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 4.3 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.7 GO:0034657 GID complex(GO:0034657)
0.2 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 3.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 3.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.4 GO:0030478 actin cap(GO:0030478)
0.2 3.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 8.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.4 GO:0097386 glial cell projection(GO:0097386)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 19.7 GO:0030018 Z disc(GO:0030018)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 4.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.1 GO:0005929 cilium(GO:0005929)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0005712 chiasma(GO:0005712)
0.1 1.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 1.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 4.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 3.5 GO:0005776 autophagosome(GO:0005776)
0.0 4.2 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.8 GO:0042383 sarcolemma(GO:0042383)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.0 3.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.6 2.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.4 3.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 1.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 1.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 0.9 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.3 0.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 5.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 3.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 3.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 9.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.5 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.2 1.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 4.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 3.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 3.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0033265 choline binding(GO:0033265)
0.1 1.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 8.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 5.4 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 3.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 5.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 2.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 2.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 2.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 10.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.9 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 5.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 5.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 17.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.0 PID IGF1 PATHWAY IGF1 pathway
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 5.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 1.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.2 5.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 7.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 4.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 3.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 5.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins