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Illumina Body Map 2: averaged replicates
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Results for FOXQ1
Z-value: 1.74
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Transcription factors associated with FOXQ1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXQ1 | hg19_v2_chr6_+_1312675_1312701 | 0.52 | 2.4e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_107020963 Show fit | 4.13 |
ENST00000509000.2
|
nuclear cap binding protein subunit 2-like |
|
| chr6_-_52628271 Show fit | 3.77 |
ENST00000493422.1
|
glutathione S-transferase alpha 2 |
|
| chr11_-_26593649 Show fit | 3.06 |
ENST00000455601.2
|
mucin 15, cell surface associated |
|
| chr12_-_91574142 Show fit | 3.00 |
ENST00000547937.1
|
decorin |
|
| chr6_-_52774464 Show fit | 2.82 |
ENST00000370968.1
ENST00000211122.3 |
glutathione S-transferase alpha 3 |
|
| chr21_-_31588365 Show fit | 2.69 |
ENST00000399899.1
|
claudin 8 |
|
| chr11_-_26593779 Show fit | 2.67 |
ENST00000529533.1
|
mucin 15, cell surface associated |
|
| chr11_-_26593677 Show fit | 2.60 |
ENST00000527569.1
|
mucin 15, cell surface associated |
|
| chr21_-_31588338 Show fit | 2.54 |
ENST00000286809.1
|
claudin 8 |
|
| chrX_+_105936982 Show fit | 2.36 |
ENST00000418562.1
|
ring finger protein 128, E3 ubiquitin protein ligase |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXQ1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.2 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.2 | 8.8 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.1 | 5.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 4.1 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 3.8 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 3.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 1.1 | 3.4 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 0.0 | 3.2 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 3.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.2 | 3.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 6.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.7 | 4.1 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.0 | 3.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 3.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 3.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 3.2 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.2 | 3.0 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 2.9 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 2.6 | GO:0042641 | actomyosin(GO:0042641) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 5.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 5.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 4.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 4.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.2 | 3.4 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 2.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 2.7 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 2.6 | GO:0038064 | protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 4.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 4.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 3.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 3.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 1.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.7 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 1.4 | PID NECTIN PATHWAY | Nectin adhesion pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 7.6 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 5.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 3.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 3.0 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.2 | 2.9 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 2.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.9 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 1.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.8 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |