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Illumina Body Map 2: averaged replicates

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Results for GATA1_GATA4

Z-value: 3.11

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.9 GATA1
ENSG00000136574.13 GATA4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA4hg19_v2_chr8_+_11561660_115617510.251.6e-01Click!
GATA1hg19_v2_chrX_+_48644962_48644983-0.019.6e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_99531709 10.01 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr18_+_19749386 8.03 ENST00000269216.3
GATA6
GATA binding protein 6
chr12_-_114841703 7.97 ENST00000526441.1
TBX5
T-box 5
chr11_-_116708302 6.95 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr19_-_55669093 6.83 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr1_-_27240455 6.31 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr10_-_48416849 6.04 ENST00000249598.1
GDF2
growth differentiation factor 2
chr11_-_47374246 5.71 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr2_-_69098566 5.67 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr7_-_99277610 5.65 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr17_+_4675175 5.58 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr7_-_99381884 5.26 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr3_+_148583043 5.12 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr1_-_201368653 5.08 ENST00000367313.3
LAD1
ladinin 1
chr3_-_187009646 5.01 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr4_-_72649763 4.95 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr1_-_201368707 4.89 ENST00000391967.2
LAD1
ladinin 1
chr1_-_209975494 4.79 ENST00000456314.1
IRF6
interferon regulatory factor 6
chr3_-_187009798 4.60 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr3_+_156807663 4.58 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr7_-_99332719 4.49 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr11_+_75428857 4.29 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr7_-_99381798 4.12 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr10_-_129691195 4.11 ENST00000368671.3
CLRN3
clarin 3
chr17_-_64225508 3.85 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_102928009 3.82 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr19_-_39303576 3.79 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr8_-_86290333 3.75 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr4_-_186697044 3.66 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr8_+_40010989 3.64 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr3_-_187009468 3.59 ENST00000425937.1
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr4_-_65275100 3.53 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr12_-_21928515 3.51 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr13_+_24144509 3.47 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr20_+_43029911 3.47 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr14_-_65409438 3.45 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_65409502 3.42 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr4_+_74702214 3.39 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr1_-_120311517 3.36 ENST00000369406.3
ENST00000544913.2
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr6_-_107235331 3.12 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr2_+_3642545 3.10 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr16_+_215965 3.09 ENST00000356815.3
HBM
hemoglobin, mu
chr4_-_186733363 3.07 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr4_-_185820602 3.04 ENST00000515864.1
ENST00000507183.1
RP11-701P16.4
long intergenic non-protein coding RNA 1093
chr3_-_119379427 2.92 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr7_-_100239132 2.91 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr1_+_199996733 2.82 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr4_-_186733119 2.81 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_44066101 2.80 ENST00000272286.2
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chrX_+_110754888 2.80 ENST00000569275.1
ENST00000563467.1
LINC00890
long intergenic non-protein coding RNA 890
chrX_+_38211777 2.77 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr4_-_186696636 2.76 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_30128657 2.74 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr1_-_24469602 2.74 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr4_-_186696561 2.66 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr7_+_80275621 2.65 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_120365866 2.64 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr7_-_44180673 2.57 ENST00000457314.1
ENST00000447951.1
ENST00000431007.1
MYL7
myosin, light chain 7, regulatory
chr1_+_199996702 2.57 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_+_234600253 2.53 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_+_11650709 2.53 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr3_-_58196688 2.52 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr2_-_88427568 2.46 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr10_-_21186144 2.45 ENST00000377119.1
NEBL
nebulette
chr7_-_44180884 2.44 ENST00000458240.1
ENST00000223364.3
MYL7
myosin, light chain 7, regulatory
chr12_+_109569155 2.42 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr21_-_37852359 2.42 ENST00000399137.1
ENST00000399135.1
CLDN14
claudin 14
chr12_-_10151773 2.42 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr13_+_24144796 2.42 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_-_186732892 2.38 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr9_+_33240157 2.38 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr12_-_103344615 2.37 ENST00000546844.1
PAH
phenylalanine hydroxylase
chr2_-_44065946 2.37 ENST00000260645.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr4_+_69962185 2.29 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_-_238108575 2.28 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr2_+_102927962 2.27 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr1_+_81771806 2.26 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr4_+_169552748 2.23 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr4_+_74269956 2.20 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr6_-_46889694 2.19 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr4_-_65275162 2.16 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr2_-_44065889 2.13 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr2_+_234545092 2.12 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr6_-_107235287 2.11 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr2_+_234627424 2.10 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr11_+_34642656 2.08 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr1_-_155270770 2.07 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr4_+_74275057 2.07 ENST00000511370.1
ALB
albumin
chr2_-_202298268 2.06 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr10_+_96698406 2.06 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr3_+_151531859 2.04 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr7_+_80275663 2.03 ENST00000413265.1
CD36
CD36 molecule (thrombospondin receptor)
chr11_+_10326612 2.00 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr11_-_5255861 1.99 ENST00000380299.3
HBD
hemoglobin, delta
chr2_+_234580499 1.99 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr14_+_24584508 1.98 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr10_+_96443204 1.97 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr12_-_54689532 1.97 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chrX_+_48380205 1.96 ENST00000446158.1
ENST00000414061.1
EBP
emopamil binding protein (sterol isomerase)
chr12_+_56477093 1.96 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr2_+_234621551 1.93 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr21_-_43786634 1.93 ENST00000291527.2
TFF1
trefoil factor 1
chr2_-_40739501 1.92 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chrX_-_55057403 1.87 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2
aminolevulinate, delta-, synthase 2
chr6_-_86099898 1.83 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr7_+_80275752 1.82 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr11_+_58695096 1.81 ENST00000525608.1
ENST00000526351.1
GLYATL1
glycine-N-acyltransferase-like 1
chr9_+_90341024 1.81 ENST00000340342.6
ENST00000342020.5
CTSL
cathepsin L
chr16_+_71560154 1.81 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr6_-_52628271 1.81 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr3_-_119379719 1.80 ENST00000493094.1
POPDC2
popeye domain containing 2
chr7_+_100547156 1.76 ENST00000379458.4
MUC3A
Protein LOC100131514
chr18_-_24722995 1.76 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr8_-_72268968 1.76 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr19_+_7741968 1.76 ENST00000597445.1
C19orf59
chromosome 19 open reading frame 59
chr4_-_103266219 1.75 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_-_11494975 1.75 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr12_-_9268707 1.74 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr13_-_28896641 1.73 ENST00000543394.1
FLT1
fms-related tyrosine kinase 1
chr6_-_31846744 1.71 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4
solute carrier family 44, member 4
chr3_+_148447887 1.69 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr13_+_28527647 1.68 ENST00000567234.1
LINC00543
long intergenic non-protein coding RNA 543
chr2_+_234959376 1.67 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr6_+_50061315 1.66 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr16_+_31539183 1.65 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chr16_+_71560023 1.65 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr1_+_86934526 1.65 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr8_-_72268889 1.64 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr16_-_67978016 1.64 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr8_-_72268721 1.64 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr11_+_58695174 1.62 ENST00000317391.4
GLYATL1
glycine-N-acyltransferase-like 1
chr12_-_120765565 1.61 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr16_+_58059470 1.61 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr8_+_76452097 1.58 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr6_+_118869452 1.58 ENST00000357525.5
PLN
phospholamban
chr2_+_138722028 1.57 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr2_+_234959323 1.57 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr3_-_178103144 1.56 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr4_-_100140331 1.55 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr3_-_194188956 1.55 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr14_+_24584372 1.55 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11
DDB1 and CUL4 associated factor 11
chr20_-_49307897 1.54 ENST00000535356.1
FAM65C
family with sequence similarity 65, member C
chr1_-_232651312 1.53 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chrX_-_65253506 1.53 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr8_+_11534462 1.53 ENST00000528712.1
ENST00000532977.1
GATA4
GATA binding protein 4
chr12_-_53297432 1.52 ENST00000546900.1
KRT8
keratin 8
chr1_-_155271213 1.52 ENST00000342741.4
PKLR
pyruvate kinase, liver and RBC
chr17_-_79817091 1.52 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr20_-_49308048 1.51 ENST00000327979.2
FAM65C
family with sequence similarity 65, member C
chr12_-_14996355 1.50 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr6_-_56112323 1.50 ENST00000535941.1
COL21A1
collagen, type XXI, alpha 1
chr5_+_1201703 1.49 ENST00000304460.10
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr12_+_6419877 1.48 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr10_+_70847852 1.47 ENST00000242465.3
SRGN
serglycin
chrX_-_84634708 1.47 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chrX_-_15402498 1.44 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr19_-_33360647 1.44 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr14_-_21566731 1.43 ENST00000360947.3
ZNF219
zinc finger protein 219
chr11_+_69831982 1.43 ENST00000534086.1
RP11-626H12.1
RP11-626H12.1
chr7_-_107443652 1.43 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr9_+_34652164 1.42 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr19_+_36132631 1.42 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr22_-_43042968 1.41 ENST00000407623.3
ENST00000396303.3
ENST00000438270.1
CYB5R3
cytochrome b5 reductase 3
chr8_+_121137333 1.38 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr4_-_48683188 1.38 ENST00000505759.1
FRYL
FRY-like
chr14_+_64680854 1.37 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr19_+_4153598 1.37 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr15_+_36887069 1.37 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr1_-_109849612 1.36 ENST00000357155.1
MYBPHL
myosin binding protein H-like
chrX_-_84634737 1.35 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr7_+_100318423 1.34 ENST00000252723.2
EPO
erythropoietin
chr9_-_95244781 1.33 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr1_+_206317450 1.33 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
CTSE
cathepsin E
chr3_+_195943369 1.32 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr22_-_43042955 1.31 ENST00000402438.1
CYB5R3
cytochrome b5 reductase 3
chr4_+_169418195 1.31 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chrX_-_100129320 1.29 ENST00000372966.3
NOX1
NADPH oxidase 1
chr4_+_169418255 1.28 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr12_-_71031185 1.28 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr16_+_85832146 1.27 ENST00000565078.1
COX4I1
cytochrome c oxidase subunit IV isoform 1
chr11_+_10326918 1.27 ENST00000528544.1
ADM
adrenomedullin
chr7_-_87936195 1.27 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4
STEAP family member 4
chr2_+_5832799 1.26 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr1_-_205912577 1.26 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr2_+_201994569 1.26 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_96390108 1.23 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr1_-_120354079 1.23 ENST00000354219.1
ENST00000369401.4
ENST00000256585.5
REG4
regenerating islet-derived family, member 4
chr2_+_103035102 1.22 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_202431859 1.22 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr11_+_34654011 1.22 ENST00000531794.1
EHF
ets homologous factor
chr12_-_71031220 1.22 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr16_+_66429358 1.22 ENST00000539168.1
CDH5
cadherin 5, type 2 (vascular endothelium)
chr4_+_74606223 1.22 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr6_-_107235378 1.21 ENST00000606430.1
RP1-60O19.1
RP1-60O19.1
chr1_-_11918988 1.20 ENST00000376468.3
NPPB
natriuretic peptide B
chr1_+_206317591 1.20 ENST00000432969.2
CTSE
cathepsin E
chr19_+_16999966 1.20 ENST00000599210.1
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr14_+_88490894 1.20 ENST00000556033.1
ENST00000553929.1
ENST00000555996.1
ENST00000556673.1
ENST00000557339.1
ENST00000556684.1
RP11-300J18.3
long intergenic non-protein coding RNA 1146
chr5_+_32788945 1.19 ENST00000326958.1
AC026703.1
AC026703.1
chr3_-_58196939 1.18 ENST00000394549.2
ENST00000461914.3
DNASE1L3
deoxyribonuclease I-like 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.6 GO:0009822 alkaloid catabolic process(GO:0009822)
2.7 8.0 GO:0007493 endodermal cell fate determination(GO:0007493)
2.7 8.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.4 7.3 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
1.7 7.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.4 10.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.4 4.3 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.1 18.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.1 4.5 GO:0002933 lipid hydroxylation(GO:0002933)
1.0 3.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.9 2.8 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.9 6.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.9 6.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.8 10.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.8 4.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.7 5.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.7 4.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.7 1.4 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.7 2.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.7 2.7 GO:0002432 granuloma formation(GO:0002432)
0.6 5.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6 2.5 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.6 10.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.6 3.6 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.6 2.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.6 1.7 GO:0048925 lateral line system development(GO:0048925)
0.6 5.6 GO:0006591 ornithine metabolic process(GO:0006591)
0.6 3.3 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.5 1.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.5 1.6 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.5 2.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.5 2.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.5 1.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.9 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 0.9 GO:0051552 flavone metabolic process(GO:0051552)
0.4 1.3 GO:0061386 closure of optic fissure(GO:0061386)
0.4 2.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.4 0.8 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.4 1.5 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.4 1.5 GO:0003289 atrial septum primum morphogenesis(GO:0003289) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.4 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.4 3.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.4 7.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 5.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.4 0.4 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.4 17.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.0 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 1.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.3 1.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 2.4 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.6 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 3.3 GO:0097647 progesterone biosynthetic process(GO:0006701) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 2.0 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.3 1.9 GO:0001692 histamine metabolic process(GO:0001692)
0.3 3.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 0.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 0.8 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.3 1.4 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.3 0.8 GO:0031247 actin rod assembly(GO:0031247)
0.3 1.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 3.5 GO:0006477 protein sulfation(GO:0006477)
0.3 1.0 GO:0042640 anagen(GO:0042640)
0.3 1.3 GO:0061107 seminal vesicle development(GO:0061107)
0.3 0.8 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.2 0.5 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.2 1.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 1.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 0.7 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 1.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 2.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.6 GO:0034378 chylomicron assembly(GO:0034378)
0.2 0.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 4.9 GO:0002003 angiotensin maturation(GO:0002003)
0.2 7.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 1.1 GO:0071504 cellular response to heparin(GO:0071504)
0.2 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.0 GO:0090341 regulation of secretion of lysosomal enzymes(GO:0090182) negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.8 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 2.4 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 0.6 GO:0010159 specification of organ position(GO:0010159)
0.2 5.2 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 0.6 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.9 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 3.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.2 3.7 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.2 0.4 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 0.6 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 4.7 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0015811 L-cystine transport(GO:0015811)
0.2 0.5 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 0.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 1.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 5.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.7 GO:0051413 response to cortisone(GO:0051413)
0.2 2.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 3.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.2 GO:0036482 neuron death in response to hydrogen peroxide(GO:0036476) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.2 1.3 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.3 GO:0043627 response to estrogen(GO:0043627)
0.2 2.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 1.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 4.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 3.0 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 1.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.8 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 4.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.8 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.5 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.1 1.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 1.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:0002215 defense response to nematode(GO:0002215)
0.1 2.5 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.8 GO:0035931 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:1990523 bone regeneration(GO:1990523)
0.1 1.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 2.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.6 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.3 GO:0051100 negative regulation of binding(GO:0051100)
0.1 1.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 2.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.6 GO:1904044 response to aldosterone(GO:1904044)
0.1 0.7 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.4 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 2.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.9 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.5 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.0 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 2.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 2.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396) tetrahydrofolate biosynthetic process(GO:0046654)
0.1 1.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 2.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.7 GO:0006525 arginine metabolic process(GO:0006525)
0.1 0.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.4 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.9 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 1.7 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.2 GO:0050900 leukocyte migration(GO:0050900)
0.1 2.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.4 GO:0015853 adenine transport(GO:0015853)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 8.2 GO:0031100 organ regeneration(GO:0031100)
0.1 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 3.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.6 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.8 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 6.9 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.7 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.9 GO:0016556 mRNA modification(GO:0016556)
0.1 1.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.9 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.6 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.8 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.3 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 1.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0090383 phagosome maturation(GO:0090382) phagosome acidification(GO:0090383)
0.0 0.5 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 1.8 GO:0010039 response to iron ion(GO:0010039)
0.0 1.0 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 1.0 GO:1903747 regulation of protein targeting to mitochondrion(GO:1903214) regulation of establishment of protein localization to mitochondrion(GO:1903747) positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 3.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 1.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 1.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.6 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 4.8 GO:0002027 regulation of heart rate(GO:0002027)
0.0 5.1 GO:0001942 hair follicle development(GO:0001942)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 1.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 1.3 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.7 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 2.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0 0.3 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 1.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.0 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 2.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.9 GO:0046849 bone remodeling(GO:0046849)
0.0 0.1 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.7 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0031214 biomineral tissue development(GO:0031214)
0.0 1.3 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.8 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0050954 sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.9 GO:0042493 response to drug(GO:0042493)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0050953 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.3 GO:0009967 positive regulation of signal transduction(GO:0009967)
0.0 0.5 GO:0002931 response to ischemia(GO:0002931)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.0 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.3 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.3 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.7 7.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.3 7.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.6 9.9 GO:0005833 hemoglobin complex(GO:0005833)
0.5 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 1.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4 3.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 1.3 GO:0036024 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.4 7.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 6.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 4.7 GO:0042383 sarcolemma(GO:0042383)
0.3 0.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 1.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.3 1.9 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.8 GO:0036021 endolysosome lumen(GO:0036021)
0.3 2.8 GO:0031090 organelle membrane(GO:0031090)
0.2 1.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 2.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 3.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.2 1.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.6 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 5.8 GO:0031672 A band(GO:0031672)
0.1 2.5 GO:0045179 apical cortex(GO:0045179)
0.1 1.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 3.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 3.1 GO:0042588 zymogen granule(GO:0042588)
0.1 1.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 28.5 GO:0030018 Z disc(GO:0030018)
0.1 1.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 9.6 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 15.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 13.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:0097413 Lewy body(GO:0097413)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 5.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 1.7 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 2.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.9 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 6.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 5.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 3.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.0 2.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 32.8 GO:0005615 extracellular space(GO:0005615)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 25.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 6.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 9.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.4 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
2.0 6.1 GO:0002113 interleukin-33 binding(GO:0002113)
1.7 7.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.7 5.0 GO:1902271 D3 vitamins binding(GO:1902271)
1.1 3.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.9 3.5 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.9 3.4 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.9 6.8 GO:0030172 troponin C binding(GO:0030172)
0.8 2.4 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.7 2.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.7 2.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.7 4.0 GO:0004882 androgen receptor activity(GO:0004882)
0.6 4.5 GO:0016936 galactoside binding(GO:0016936)
0.6 1.9 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 3.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 6.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 1.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.6 3.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 4.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.5 1.5 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5 3.8 GO:0004064 arylesterase activity(GO:0004064)
0.5 10.6 GO:0070330 aromatase activity(GO:0070330)
0.5 2.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 1.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 3.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4 6.2 GO:0031433 telethonin binding(GO:0031433)
0.4 1.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 2.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.4 2.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 7.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.4 2.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.4 17.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 2.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 8.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 0.9 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 1.8 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.3 5.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 1.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 1.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 1.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 1.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481) chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.2 13.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 4.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.3 GO:0005497 androgen binding(GO:0005497)
0.2 1.7 GO:0045118 azole transporter activity(GO:0045118)
0.2 7.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.8 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 4.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 2.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 5.0 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 1.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 3.8 GO:0005537 mannose binding(GO:0005537)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 2.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 5.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 1.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 2.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 1.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 3.1 GO:0042301 phosphate ion binding(GO:0042301)
0.1 2.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.3 GO:0032190 acrosin binding(GO:0032190)
0.1 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 4.0 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 7.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 1.0 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 1.0 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.7 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 1.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 10.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 8.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 3.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.0 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 2.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 2.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 2.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 5.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 4.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 8.2 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 1.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 3.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 3.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.6 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.6 GO:0051213 dioxygenase activity(GO:0051213)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 2.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 11.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 3.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 7.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 19.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 9.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 6.6 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 4.3 PID INSULIN PATHWAY Insulin Pathway
0.1 4.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.4 PID EPO PATHWAY EPO signaling pathway
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 5.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 17.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 4.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 12.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 14.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 24.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.9 13.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 14.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 10.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 8.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 3.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 14.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 3.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 6.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 5.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 7.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 9.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 13.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 6.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 11.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 4.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.7 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.0 1.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 10.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation