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Illumina Body Map 2: averaged replicates

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Results for GATA5

Z-value: 1.95

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Transcription factors associated with GATA5

Gene Symbol Gene ID Gene Info
GATA5
ENSG00000130700.6 GATA binding protein 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA5hg19_v2_chr20_-_61051026_61051057-0.281.2e-01Click!

Activity profile of GATA5 motif

Sorted Z-values of GATA5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 8.73 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 7.54 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_-_72649763 5.77 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr1_+_57320437 5.62 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr15_-_54025300 4.13 ENST00000559418.1
WDR72
WD repeat domain 72
chr21_+_39668478 4.01 ENST00000398927.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_75904918 3.91 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr5_+_75904950 3.58 ENST00000502745.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_+_102615416 3.08 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr10_+_7745303 3.05 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_196857144 2.98 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr10_+_7745232 2.87 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr9_-_6645628 2.74 ENST00000321612.6
GLDC
glycine dehydrogenase (decarboxylating)
chr20_-_7238861 2.59 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr6_-_135271260 2.40 ENST00000265605.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr6_-_135271219 2.39 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chrX_-_55020511 2.29 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_-_121825088 2.21 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr2_-_109605663 2.11 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr6_+_78400375 2.02 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr11_-_62911693 1.90 ENST00000417740.1
ENST00000326192.5
SLC22A24
solute carrier family 22, member 24
chrM_+_3299 1.90 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr4_+_110834033 1.87 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr19_-_52133588 1.84 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr13_-_99910620 1.83 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr17_+_6939362 1.79 ENST00000308027.6
SLC16A13
solute carrier family 16, member 13
chrM_+_10758 1.77 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr8_-_66750978 1.77 ENST00000523253.1
PDE7A
phosphodiesterase 7A
chr12_+_20968608 1.73 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_197300194 1.73 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr1_+_150954493 1.66 ENST00000368947.4
ANXA9
annexin A9
chr6_-_133055896 1.58 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr6_+_53964336 1.54 ENST00000447836.2
ENST00000511678.1
MLIP
muscular LMNA-interacting protein
chr2_+_143635067 1.49 ENST00000264170.4
KYNU
kynureninase
chr9_+_6645887 1.48 ENST00000413145.1
RP11-390F4.6
RP11-390F4.6
chr14_-_24553834 1.47 ENST00000397002.2
NRL
neural retina leucine zipper
chr21_-_31864275 1.41 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr16_+_82068585 1.39 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr6_-_86099898 1.37 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr12_-_110883346 1.35 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_140175987 1.35 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr13_+_32313658 1.33 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr10_-_98031265 1.32 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr1_-_159505842 1.32 ENST00000334857.2
OR10J5
olfactory receptor, family 10, subfamily J, member 5
chr14_+_35591020 1.28 ENST00000603611.1
KIAA0391
KIAA0391
chr11_+_22694123 1.27 ENST00000534801.1
GAS2
growth arrest-specific 2
chr12_+_10331605 1.27 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr1_-_17445930 1.25 ENST00000375486.4
ENST00000375481.1
ENST00000444885.2
PADI2
peptidyl arginine deiminase, type II
chr6_-_133079022 1.24 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr19_-_10450328 1.22 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr16_+_82068873 1.21 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr10_+_5090940 1.19 ENST00000602997.1
AKR1C3
aldo-keto reductase family 1, member C3
chr8_-_6875778 1.19 ENST00000535841.1
ENST00000327857.2
DEFA1B
DEFA3
defensin, alpha 1B
defensin, alpha 3, neutrophil-specific
chr5_+_145316120 1.15 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr14_+_39735411 1.15 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr8_-_6837602 1.15 ENST00000382692.2
DEFA1
defensin, alpha 1
chrM_+_10464 1.10 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr1_+_207277590 1.10 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr15_-_49913126 1.10 ENST00000561064.1
ENST00000299338.6
FAM227B
family with sequence similarity 227, member B
chr6_-_4347271 1.05 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr17_+_1633755 1.05 ENST00000545662.1
WDR81
WD repeat domain 81
chr14_+_22928070 1.04 ENST00000390476.1
TRDJ3
T cell receptor delta joining 3
chr14_+_21785693 1.03 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr12_+_9102632 1.02 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr12_-_14967095 1.00 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr6_-_52710893 0.97 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr15_+_99791716 0.96 ENST00000558172.1
ENST00000561276.1
ENST00000331450.5
LRRC28
leucine rich repeat containing 28
chr14_+_22995812 0.96 ENST00000390520.1
TRAJ17
T cell receptor alpha joining 17
chr11_+_121461097 0.96 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_102927962 0.95 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr7_+_26332645 0.95 ENST00000396376.1
SNX10
sorting nexin 10
chr2_+_102928009 0.94 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr6_-_24936170 0.94 ENST00000538035.1
FAM65B
family with sequence similarity 65, member B
chr15_-_49912944 0.93 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr17_-_41277467 0.90 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
BRCA1
breast cancer 1, early onset
chr3_+_169755919 0.90 ENST00000492492.1
GPR160
G protein-coupled receptor 160
chr1_+_174844645 0.89 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr6_+_10634158 0.89 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr2_+_201997676 0.86 ENST00000462763.1
ENST00000479953.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_+_20831460 0.85 ENST00000522604.1
RP11-421P23.1
RP11-421P23.1
chr3_+_169755715 0.85 ENST00000355897.5
GPR160
G protein-coupled receptor 160
chr4_-_83765613 0.85 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr6_+_31916733 0.84 ENST00000483004.1
CFB
complement factor B
chr1_-_157670647 0.83 ENST00000368184.3
FCRL3
Fc receptor-like 3
chr19_-_14889349 0.82 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr6_+_10633993 0.82 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr14_+_22475742 0.81 ENST00000390447.3
TRAV19
T cell receptor alpha variable 19
chr4_-_47983519 0.80 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr22_+_21213771 0.80 ENST00000439214.1
SNAP29
synaptosomal-associated protein, 29kDa
chr11_-_61734599 0.78 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr2_-_191115229 0.78 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr7_-_142251148 0.77 ENST00000390360.3
TRBV6-4
T cell receptor beta variable 6-4
chr13_-_99910673 0.76 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr4_-_65275100 0.76 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr6_-_55739542 0.76 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr7_-_123197733 0.76 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr1_+_207277632 0.76 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr8_+_93895865 0.75 ENST00000391681.1
AC117834.1
AC117834.1
chr1_-_11918988 0.75 ENST00000376468.3
NPPB
natriuretic peptide B
chr10_-_14596140 0.74 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr4_+_108815402 0.74 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr3_-_182817297 0.74 ENST00000539926.1
ENST00000476176.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr18_+_21032781 0.73 ENST00000339486.3
RIOK3
RIO kinase 3
chr1_+_62439037 0.73 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_+_115572415 0.72 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr6_+_106988986 0.71 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr9_-_35650900 0.70 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr8_+_132952112 0.70 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr11_-_72070206 0.69 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_+_78245466 0.69 ENST00000477627.2
FAM73A
family with sequence similarity 73, member A
chr1_+_196743943 0.69 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr3_-_51813009 0.68 ENST00000398780.3
IQCF6
IQ motif containing F6
chr14_-_22103096 0.67 ENST00000542433.1
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr4_-_65275162 0.67 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr14_+_67291158 0.65 ENST00000555456.1
GPHN
gephyrin
chr7_+_74379083 0.63 ENST00000361825.7
GATSL1
GATS protein-like 1
chr20_+_32254286 0.63 ENST00000330271.4
ACTL10
actin-like 10
chr9_-_98189055 0.62 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr6_-_53409890 0.62 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr9_-_123239632 0.62 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr4_-_48782259 0.61 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr8_+_58106143 0.61 ENST00000521653.1
ENST00000518556.1
RP11-513O17.2
RP11-513O17.2
chr2_+_182850551 0.61 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr8_-_91095099 0.60 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_+_156123318 0.60 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_156878482 0.60 ENST00000295925.4
CCNL1
cyclin L1
chr3_+_193311056 0.59 ENST00000419435.1
OPA1
optic atrophy 1 (autosomal dominant)
chrM_+_10053 0.59 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr12_+_40549984 0.58 ENST00000457989.1
AC079630.2
AC079630.2
chr7_+_142448053 0.57 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr6_-_32908765 0.57 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_-_157014865 0.57 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr1_-_27226928 0.57 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr3_+_193310969 0.57 ENST00000392437.1
OPA1
optic atrophy 1 (autosomal dominant)
chr11_+_128563652 0.57 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr14_+_23000026 0.55 ENST00000390524.1
TRAJ13
T cell receptor alpha joining 13
chr15_+_99791567 0.55 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
LRRC28
leucine rich repeat containing 28
chr14_+_22392209 0.55 ENST00000390440.2
TRAV14DV4
T cell receptor alpha variable 14/delta variable 4
chr17_+_36908984 0.54 ENST00000225426.4
ENST00000579088.1
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr22_-_21213676 0.53 ENST00000449120.1
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr3_+_193311105 0.52 ENST00000392436.2
OPA1
optic atrophy 1 (autosomal dominant)
chr2_+_62132781 0.52 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chr2_-_47143160 0.51 ENST00000409800.1
ENST00000409218.1
MCFD2
multiple coagulation factor deficiency 2
chr17_-_40170506 0.51 ENST00000589773.1
ENST00000590348.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr22_+_17956618 0.51 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr10_-_114206649 0.50 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr7_-_55583740 0.50 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr9_-_70490107 0.49 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr12_-_57882577 0.49 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr2_-_122247879 0.49 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chr5_-_58652788 0.48 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_133615169 0.48 ENST00000541309.1
EXOC4
exocyst complex component 4
chrX_+_79675965 0.48 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr16_-_28503357 0.47 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr15_+_100106244 0.47 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr3_+_177545563 0.46 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr3_+_46283916 0.46 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr17_-_45908875 0.46 ENST00000351111.2
ENST00000414011.1
MRPL10
mitochondrial ribosomal protein L10
chr1_+_10292308 0.45 ENST00000377081.1
KIF1B
kinesin family member 1B
chr8_+_27629459 0.45 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr13_+_108870714 0.45 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr3_+_46283944 0.45 ENST00000452454.1
ENST00000457243.1
CCR3
chemokine (C-C motif) receptor 3
chr2_+_227771404 0.45 ENST00000409053.1
RHBDD1
rhomboid domain containing 1
chr11_+_110225855 0.45 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr3_+_46283863 0.45 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr3_+_193310918 0.45 ENST00000361908.3
ENST00000392438.3
ENST00000361510.2
ENST00000361715.2
ENST00000361828.2
ENST00000361150.2
OPA1
optic atrophy 1 (autosomal dominant)
chr7_+_16793160 0.44 ENST00000262067.4
TSPAN13
tetraspanin 13
chr2_-_197226875 0.44 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr5_+_147774275 0.44 ENST00000513826.1
FBXO38
F-box protein 38
chr2_+_201997595 0.44 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_-_107289490 0.43 ENST00000277216.3
OR13C4
olfactory receptor, family 13, subfamily C, member 4
chr4_-_88244010 0.43 ENST00000302219.6
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr1_-_160681593 0.43 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chr17_+_41322483 0.42 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
NBR1
neighbor of BRCA1 gene 1
chr5_-_150537279 0.42 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr14_-_23103716 0.42 ENST00000540461.1
OR6J1
olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene)
chr12_+_54892550 0.41 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr4_-_88244049 0.41 ENST00000328546.4
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr3_-_108476231 0.41 ENST00000295755.6
RETNLB
resistin like beta
chr11_-_14379997 0.40 ENST00000526063.1
ENST00000532814.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr3_+_108541608 0.40 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr4_-_100575781 0.39 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr1_-_100643765 0.39 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr11_-_33891362 0.38 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr6_-_15548591 0.38 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr14_+_62164340 0.38 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr2_-_128642434 0.38 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr5_+_169758393 0.38 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
CTB-114C7.3
chr14_+_61995722 0.37 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr8_-_42360015 0.37 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr2_+_201997492 0.37 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr10_+_15085918 0.37 ENST00000378225.1
OLAH
oleoyl-ACP hydrolase
chr15_+_45028753 0.37 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr1_-_17380630 0.36 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr15_+_100106155 0.36 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr6_-_117150198 0.36 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr6_-_154677900 0.36 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr2_-_224810070 0.36 ENST00000429915.1
ENST00000233055.4
WDFY1
WD repeat and FYVE domain containing 1
chr4_-_175204765 0.35 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr15_-_34628951 0.35 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 16.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.8 3.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.6 2.6 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.5 2.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 4.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.4 1.2 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.4 1.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 1.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 1.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.3 2.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 2.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 1.0 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 1.3 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.3 0.9 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.3 1.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.3 7.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.3 1.9 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.9 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 6.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.8 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.2 1.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.6 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 4.1 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 1.3 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.3 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.2 5.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.8 GO:0016240 autophagosome docking(GO:0016240)
0.2 2.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.6 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2 2.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 1.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.8 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.1 0.5 GO:1904647 response to rotenone(GO:1904647)
0.1 1.9 GO:0015747 urate transport(GO:0015747)
0.1 2.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.6 GO:1990748 detoxification(GO:0098754) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.4 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 1.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 6.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 5.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.7 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 4.0 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 1.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:1904430 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 2.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.9 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.5 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 16.3 GO:0005577 fibrinogen complex(GO:0005577)
0.9 2.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.6 5.6 GO:0005579 membrane attack complex(GO:0005579)
0.2 0.9 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 0.8 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 2.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 1.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 0.6 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.8 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.7 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.5 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0019034 viral replication complex(GO:0019034)
0.1 8.4 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 2.0 GO:0000800 lateral element(GO:0000800)
0.1 6.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 12.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 1.9 GO:0002113 interleukin-33 binding(GO:0002113)
0.6 3.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.5 7.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 2.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.5 2.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 1.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 1.2 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.4 4.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 2.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 1.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.6 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 4.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.1 GO:1901612 cardiolipin binding(GO:1901612)
0.2 6.5 GO:0001848 complement binding(GO:0001848)
0.2 0.6 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 2.7 GO:0016594 glycine binding(GO:0016594)
0.2 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 1.9 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 16.4 GO:0051087 chaperone binding(GO:0051087)
0.1 6.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 2.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 1.9 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.0 2.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 2.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 2.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.7 GO:0005319 lipid transporter activity(GO:0005319)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 3.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 5.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 6.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 2.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 3.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell