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Illumina Body Map 2: averaged replicates

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Results for GCM2

Z-value: 1.46

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Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
GCM2
ENSG00000124827.6 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM2hg19_v2_chr6_-_10882174_108822740.584.7e-04Click!

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_44365020 6.68 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr15_+_78632666 3.94 ENST00000299529.6
CRABP1
cellular retinoic acid binding protein 1
chr16_+_71392616 3.32 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr7_+_70597109 2.73 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr1_-_205313304 2.67 ENST00000539253.1
ENST00000607826.1
KLHDC8A
kelch domain containing 8A
chr7_-_44365216 2.61 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr2_-_193059634 2.56 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_50712672 2.53 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr19_-_38878632 2.46 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr14_+_75536280 2.35 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr17_-_7197881 2.20 ENST00000007699.5
YBX2
Y box binding protein 2
chrX_-_71526813 2.18 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr11_-_118023490 2.18 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr3_+_35681728 2.11 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr15_-_93632421 2.07 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr7_+_37960163 2.01 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr1_+_237205476 2.00 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr19_+_35783028 1.95 ENST00000600291.1
ENST00000392213.3
MAG
myelin associated glycoprotein
chrX_-_71526999 1.94 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_+_35783047 1.94 ENST00000595791.1
ENST00000597035.1
ENST00000537831.2
MAG
myelin associated glycoprotein
chr19_+_35783037 1.91 ENST00000361922.4
MAG
myelin associated glycoprotein
chr15_+_74466744 1.89 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr9_+_103340354 1.86 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr1_+_20878932 1.84 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr5_+_137774706 1.84 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr3_-_142682178 1.81 ENST00000340634.3
PAQR9
progestin and adipoQ receptor family member IX
chr14_+_75536335 1.78 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr19_+_51293672 1.77 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chr2_+_220408724 1.77 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198
transmembrane protein 198
chr2_+_220299547 1.73 ENST00000312358.7
SPEG
SPEG complex locus
chr3_+_42727011 1.70 ENST00000287777.4
KLHL40
kelch-like family member 40
chr9_-_130635741 1.65 ENST00000223836.10
AK1
adenylate kinase 1
chr11_-_83393429 1.64 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr19_-_19626351 1.63 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr14_-_77737543 1.62 ENST00000298352.4
NGB
neuroglobin
chr22_-_29457832 1.61 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr2_+_16080659 1.59 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr6_-_110500826 1.58 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr9_-_127269488 1.55 ENST00000455734.1
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr9_-_127269661 1.52 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr3_+_35681081 1.51 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_156008809 1.45 ENST00000302490.8
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_+_5019061 1.44 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr20_-_44420507 1.44 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr15_+_43809797 1.41 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr16_+_1031762 1.38 ENST00000293894.3
SOX8
SRY (sex determining region Y)-box 8
chr1_-_182642017 1.38 ENST00000367557.4
ENST00000258302.4
RGS8
regulator of G-protein signaling 8
chr2_-_220408260 1.35 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr17_-_41132088 1.34 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr14_-_59932044 1.33 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr4_-_153700864 1.31 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr17_+_48911942 1.31 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr9_+_72658490 1.29 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr9_-_127263265 1.28 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr2_-_19558373 1.26 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr6_-_110500905 1.26 ENST00000392587.2
WASF1
WAS protein family, member 1
chr19_+_41036371 1.24 ENST00000392023.1
SPTBN4
spectrin, beta, non-erythrocytic 4
chr6_-_52859968 1.22 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr14_+_42077552 1.21 ENST00000554120.1
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chrX_+_130192318 1.21 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr17_+_79989500 1.20 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr7_-_98467489 1.20 ENST00000416379.2
TMEM130
transmembrane protein 130
chr2_-_193059250 1.20 ENST00000409056.3
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_-_105635090 1.16 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chrX_+_46937745 1.13 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr1_+_43824669 1.13 ENST00000372462.1
CDC20
cell division cycle 20
chrX_+_12156582 1.12 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr8_-_98290087 1.11 ENST00000322128.3
TSPYL5
TSPY-like 5
chr13_-_47471155 1.10 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr1_+_43824577 1.10 ENST00000310955.6
CDC20
cell division cycle 20
chr17_-_42907564 1.08 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr2_-_220435963 1.08 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr2_+_220309379 1.08 ENST00000451076.1
SPEG
SPEG complex locus
chr2_-_220252603 1.06 ENST00000322176.7
ENST00000273075.4
DNPEP
aspartyl aminopeptidase
chr15_+_74421961 1.05 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_67600639 1.05 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr17_-_8021710 1.03 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr20_+_42143053 1.02 ENST00000373135.3
ENST00000444063.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr2_-_220436248 1.01 ENST00000265318.4
OBSL1
obscurin-like 1
chr16_-_25122735 0.99 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr4_-_187112626 0.98 ENST00000596414.1
AC110771.1
Uncharacterized protein
chr17_-_3796334 0.98 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr16_+_22825475 0.98 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr11_-_64410787 0.98 ENST00000301894.2
NRXN2
neurexin 2
chr15_-_41624685 0.98 ENST00000560640.1
ENST00000220514.3
OIP5
Opa interacting protein 5
chrX_+_150869023 0.97 ENST00000448324.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr11_-_118023594 0.96 ENST00000529878.1
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr17_+_53342311 0.96 ENST00000226067.5
HLF
hepatic leukemia factor
chr3_-_79068138 0.96 ENST00000495273.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_-_160975130 0.96 ENST00000274547.2
ENST00000520240.1
ENST00000517901.1
ENST00000353437.6
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr15_+_78556809 0.95 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_-_79068594 0.94 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_-_83393457 0.94 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr3_+_137490748 0.93 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr9_-_13279589 0.93 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chrX_-_27999566 0.92 ENST00000441525.1
DCAF8L1
DDB1 and CUL4 associated factor 8-like 1
chr1_+_44444865 0.92 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_-_102091144 0.92 ENST00000428343.1
RFX8
RFX family member 8, lacking RFX DNA binding domain
chr20_+_42143136 0.91 ENST00000373134.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr1_-_228613026 0.91 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr17_-_71258019 0.91 ENST00000344935.4
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr7_+_116139821 0.91 ENST00000393480.2
CAV2
caveolin 2
chrX_+_122318224 0.90 ENST00000542149.1
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr13_-_44735393 0.89 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr14_-_70038032 0.88 ENST00000543986.1
CCDC177
coiled-coil domain containing 177
chr11_-_10715033 0.88 ENST00000529547.1
ENST00000558540.1
MRVI1
murine retrovirus integration site 1 homolog
chr19_-_12886327 0.88 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr15_-_93199069 0.88 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr5_-_137878887 0.88 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr20_-_982904 0.87 ENST00000217260.4
ENST00000400634.2
RSPO4
R-spondin 4
chr8_+_117950422 0.86 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chrX_+_122318318 0.85 ENST00000371251.1
ENST00000371256.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr8_+_134125727 0.83 ENST00000521107.1
TG
thyroglobulin
chr15_-_30261066 0.83 ENST00000558447.1
TJP1
tight junction protein 1
chr21_+_27011584 0.82 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr11_-_10715117 0.81 ENST00000527509.2
MRVI1
murine retrovirus integration site 1 homolog
chr3_-_50605150 0.80 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr14_+_77647966 0.80 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr14_+_77648167 0.80 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr19_-_55954230 0.80 ENST00000376325.4
SHISA7
shisa family member 7
chr17_-_7123021 0.79 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr20_-_60982330 0.79 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr2_-_220252530 0.78 ENST00000521459.1
DNPEP
aspartyl aminopeptidase
chr14_+_105046021 0.78 ENST00000557649.1
C14orf180
chromosome 14 open reading frame 180
chr11_-_5345582 0.78 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr12_+_15125954 0.77 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr16_-_3350614 0.76 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr9_-_124976185 0.76 ENST00000464484.2
LHX6
LIM homeobox 6
chr15_-_88799384 0.75 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr7_+_116139744 0.74 ENST00000343213.2
CAV2
caveolin 2
chr4_+_95972822 0.74 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr5_-_87980587 0.71 ENST00000509783.1
ENST00000509405.1
ENST00000506978.1
ENST00000509265.1
ENST00000513805.1
LINC00461
long intergenic non-protein coding RNA 461
chr2_+_121493717 0.70 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr5_+_157170703 0.70 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr12_-_48398104 0.69 ENST00000337299.6
ENST00000380518.3
COL2A1
collagen, type II, alpha 1
chr6_-_32077100 0.69 ENST00000375244.3
ENST00000375247.2
TNXB
tenascin XB
chr3_-_50605077 0.69 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr2_-_239140276 0.69 ENST00000334973.4
AC016757.3
Protein LOC151174
chr6_-_142409936 0.69 ENST00000258042.1
NMBR
neuromedin B receptor
chr14_+_27342334 0.69 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
RP11-384J4.1
chr11_-_6341724 0.67 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr11_-_62689046 0.67 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr19_-_51530916 0.67 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr16_-_10276251 0.67 ENST00000330684.3
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr1_+_15272271 0.66 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr1_+_77748756 0.65 ENST00000478407.1
AK5
adenylate kinase 5
chr16_+_24857309 0.65 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr9_-_124976154 0.65 ENST00000482062.1
LHX6
LIM homeobox 6
chr2_+_176995011 0.64 ENST00000548663.1
ENST00000450510.2
HOXD8
homeobox D8
chr17_-_42908155 0.64 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr19_-_55953704 0.63 ENST00000416792.1
SHISA7
shisa family member 7
chr2_+_179059365 0.63 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr14_+_105046094 0.62 ENST00000331952.2
C14orf180
chromosome 14 open reading frame 180
chr2_-_220408430 0.61 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr15_-_48470544 0.59 ENST00000267836.6
MYEF2
myelin expression factor 2
chr11_+_123886282 0.59 ENST00000320891.4
OR10G4
olfactory receptor, family 10, subfamily G, member 4
chr22_-_25335314 0.57 ENST00000382744.1
TMEM211
transmembrane protein 211
chr12_-_16758873 0.57 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_99245957 0.57 ENST00000484675.1
RP11-779P15.2
RP11-779P15.2
chr15_-_48470558 0.57 ENST00000324324.7
MYEF2
myelin expression factor 2
chr16_+_3194211 0.57 ENST00000428155.1
CASP16
caspase 16, apoptosis-related cysteine peptidase (putative)
chrX_+_99839799 0.56 ENST00000373031.4
TNMD
tenomodulin
chr19_+_589893 0.56 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_107729287 0.56 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr8_-_145559943 0.56 ENST00000332135.4
SCRT1
scratch family zinc finger 1
chr2_+_168149569 0.55 ENST00000442316.1
AC074363.1
AC074363.1
chr20_+_18269121 0.55 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
ZNF133
zinc finger protein 133
chr17_-_41738931 0.55 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr11_-_9113137 0.54 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr12_-_16758835 0.54 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_-_10715163 0.53 ENST00000541483.1
MRVI1
murine retrovirus integration site 1 homolog
chr9_-_13279563 0.53 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr15_+_68115895 0.53 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chr14_+_21566980 0.52 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr7_+_150811705 0.52 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_+_639895 0.51 ENST00000586042.2
ENST00000215530.5
FGF22
fibroblast growth factor 22
chr2_-_73053126 0.50 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr2_+_179059188 0.49 ENST00000392505.2
ENST00000359685.3
ENST00000357080.4
ENST00000409045.3
OSBPL6
oxysterol binding protein-like 6
chr17_-_56565736 0.49 ENST00000323777.3
HSF5
heat shock transcription factor family member 5
chr1_+_178062855 0.49 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr5_+_140743859 0.49 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr17_-_10017864 0.48 ENST00000323816.4
GAS7
growth arrest-specific 7
chr15_+_73344911 0.48 ENST00000560262.1
ENST00000558964.1
NEO1
neogenin 1
chr3_-_11762202 0.48 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr6_+_46761118 0.47 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr3_+_126707437 0.47 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr22_-_25335502 0.46 ENST00000423535.1
TMEM211
transmembrane protein 211
chr11_-_10715287 0.46 ENST00000423302.2
MRVI1
murine retrovirus integration site 1 homolog
chr6_-_31864977 0.46 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr19_-_14316980 0.46 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr16_-_755819 0.46 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr7_-_6048702 0.44 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr19_-_51531272 0.44 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr19_-_51531210 0.44 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr19_+_17581253 0.43 ENST00000252595.7
ENST00000598424.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr5_+_113697983 0.43 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr11_-_61197406 0.43 ENST00000541963.1
ENST00000477890.2
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chrX_-_63005405 0.43 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_+_110012462 0.43 ENST00000441478.2
ENST00000230124.3
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chrX_+_128674213 0.43 ENST00000371113.4
ENST00000357121.5
OCRL
oculocerebrorenal syndrome of Lowe

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.9 4.4 GO:0007538 primary sex determination(GO:0007538)
0.8 3.9 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.7 1.4 GO:0072034 renal vesicle induction(GO:0072034)
0.7 2.0 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.6 2.2 GO:0009386 translational attenuation(GO:0009386)
0.5 11.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.5 4.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.5 1.5 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.4 1.9 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.4 5.8 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.4 1.4 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.3 1.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 1.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 1.3 GO:0023016 osmosensory signaling pathway(GO:0007231) signal transduction by trans-phosphorylation(GO:0023016) kidney smooth muscle tissue development(GO:0072194) pattern specification involved in metanephros development(GO:0072268)
0.3 1.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 1.7 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.3 0.6 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.7 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.7 GO:0033058 directional locomotion(GO:0033058)
0.2 1.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 2.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.7 GO:0006173 dADP biosynthetic process(GO:0006173)
0.2 0.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 1.7 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 0.8 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 1.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 0.5 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 0.7 GO:0061056 sclerotome development(GO:0061056)
0.2 3.1 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.2 2.6 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 1.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.7 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 2.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 1.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 1.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.8 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 1.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 2.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 1.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.4 GO:0060539 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.4 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0060174 limb bud formation(GO:0060174)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.1 2.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0001933 negative regulation of protein phosphorylation(GO:0001933) negative regulation of phosphorylation(GO:0042326)
0.1 0.9 GO:0035878 nail development(GO:0035878)
0.0 0.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.4 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.6 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 1.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 1.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 1.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.8 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 2.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 1.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.5 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288) regulation of DNA ligase activity(GO:1904875)
0.0 0.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 3.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.2 GO:0014902 myotube differentiation(GO:0014902)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.8 GO:0042476 odontogenesis(GO:0042476)
0.0 1.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.3 2.1 GO:1990393 3M complex(GO:1990393)
0.2 2.3 GO:0070852 cell body fiber(GO:0070852)
0.2 0.6 GO:0098855 HCN channel complex(GO:0098855)
0.2 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 11.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 5.9 GO:0005921 gap junction(GO:0005921)
0.1 2.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 5.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.7 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.7 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 2.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 3.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 4.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030133 transport vesicle(GO:0030133)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0032093 SAM domain binding(GO:0032093)
0.5 2.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.4 2.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 3.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 5.8 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.7 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.3 2.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 3.9 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.0 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 0.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.7 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.5 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 0.5 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.2 3.9 GO:0019841 retinol binding(GO:0019841)
0.1 10.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.9 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 1.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 2.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.7 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 1.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 2.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.4 GO:0070402 NADPH binding(GO:0070402)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 2.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.0 GO:0031208 POZ domain binding(GO:0031208)
0.0 5.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 2.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 5.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 3.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 5.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 3.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation