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Illumina Body Map 2: averaged replicates
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Results for GFI1
Z-value: 1.68
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Transcription factors associated with GFI1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GFI1 | hg19_v2_chr1_-_92952433_92952489 | -0.09 | 6.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_60539422 Show fit | 2.60 |
ENST00000371201.3
|
chromosome 1 open reading frame 87 |
|
| chr6_-_49712147 Show fit | 2.05 |
ENST00000433368.2
ENST00000354620.4 |
cysteine-rich secretory protein 3 |
|
| chr6_-_49712123 Show fit | 2.00 |
ENST00000263045.4
|
cysteine-rich secretory protein 3 |
|
| chr1_-_60539405 Show fit | 1.88 |
ENST00000450089.2
|
chromosome 1 open reading frame 87 |
|
| chr6_-_49712072 Show fit | 1.83 |
ENST00000423399.2
|
cysteine-rich secretory protein 3 |
|
| chr6_-_49712091 Show fit | 1.73 |
ENST00000371159.4
|
cysteine-rich secretory protein 3 |
|
| chr11_+_71900703 Show fit | 1.70 |
ENST00000393681.2
|
folate receptor 1 (adult) |
|
| chr11_+_71900572 Show fit | 1.52 |
ENST00000312293.4
|
folate receptor 1 (adult) |
|
| chr1_-_109655377 Show fit | 1.45 |
ENST00000369948.3
|
chromosome 1 open reading frame 194 |
|
| chr17_+_45908974 Show fit | 1.44 |
ENST00000269025.4
|
leucine rich repeat containing 46 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GFI1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0003147 | neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) |
| 0.0 | 2.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 2.4 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.5 | 2.1 | GO:0090293 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.3 | 2.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.0 | 2.1 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.1 | 1.9 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 1.9 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 1.7 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.3 | 1.5 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 3.7 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 3.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 2.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 2.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 2.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 2.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.8 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 1.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.7 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.8 | 3.2 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.1 | 2.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.5 | 2.1 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.4 | 2.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 2.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 1.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 1.0 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.0 | 1.0 | GO:0035198 | miRNA binding(GO:0035198) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.5 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 3.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 2.8 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 2.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 2.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 2.2 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.5 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 1.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 1.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.7 | PID CONE PATHWAY | Visual signal transduction: Cones |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 2.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.9 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 1.3 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 1.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 1.3 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 1.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.0 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 1.0 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |