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Illumina Body Map 2: averaged replicates

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Results for GFI1

Z-value: 1.68

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Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
GFI1
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1hg19_v2_chr1_-_92952433_92952489-0.096.3e-01Click!

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_60539422 2.60 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr6_-_49712147 2.05 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr6_-_49712123 2.00 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr1_-_60539405 1.88 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr6_-_49712072 1.83 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr6_-_49712091 1.73 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr11_+_71900703 1.70 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 1.52 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr1_-_109655377 1.45 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr17_+_45908974 1.44 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr1_-_109655355 1.44 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr2_+_11696464 1.38 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr17_+_68071389 1.35 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_-_135805008 1.29 ENST00000414343.1
MAP3K19
mitogen-activated protein kinase kinase kinase 19
chr19_-_9092018 1.25 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr4_-_155533787 1.19 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr5_+_94727048 1.18 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr11_+_34642656 1.17 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr10_+_102505468 1.15 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr17_+_68071458 1.12 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr14_-_22005343 1.10 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr9_+_2158485 1.05 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_136172820 1.05 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr10_+_70980051 1.05 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr9_+_2158443 1.03 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_85397167 1.02 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr10_+_119184702 1.02 ENST00000549104.1
CTA-109P11.4
CTA-109P11.4
chr11_-_8954491 0.99 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr10_-_73497581 0.99 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr5_+_59783540 0.95 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_156338993 0.93 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr14_-_22005197 0.89 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr6_+_152126790 0.88 ENST00000456483.2
ESR1
estrogen receptor 1
chr2_-_114036488 0.87 ENST00000263335.7
ENST00000397647.3
ENST00000348715.5
ENST00000429538.3
PAX8
paired box 8
chr19_-_10687907 0.86 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_+_15668240 0.85 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr8_+_133931648 0.83 ENST00000519178.1
ENST00000542445.1
TG
thyroglobulin
chr6_-_116447283 0.83 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr4_+_9446156 0.82 ENST00000334879.1
DEFB131
defensin, beta 131
chr12_+_100867486 0.82 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_100867694 0.79 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr21_-_36421626 0.79 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr20_+_58179582 0.79 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr14_-_22005018 0.79 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr5_+_55354822 0.77 ENST00000511861.1
CTD-2227I18.1
CTD-2227I18.1
chr3_+_119814070 0.77 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr14_-_22005062 0.77 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr2_-_89160770 0.76 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr8_-_145642203 0.75 ENST00000526658.1
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_+_54495542 0.75 ENST00000252729.2
ENST00000352529.1
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chrX_+_103294483 0.74 ENST00000355016.3
H2BFM
H2B histone family, member M
chr3_-_190580404 0.73 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr2_-_89160425 0.71 ENST00000390239.2
IGKJ4
immunoglobulin kappa joining 4
chr21_-_36421535 0.70 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr19_-_10687948 0.69 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr10_-_82049424 0.69 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr2_-_99485825 0.67 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr5_-_35230649 0.67 ENST00000382002.5
PRLR
prolactin receptor
chr5_-_35230771 0.67 ENST00000342362.5
PRLR
prolactin receptor
chrX_+_49832231 0.66 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr17_+_79495397 0.66 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr2_+_66662249 0.65 ENST00000560281.2
MEIS1
Meis homeobox 1
chr12_-_58212487 0.65 ENST00000549994.1
AVIL
advillin
chr19_-_43969796 0.65 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr14_+_22771851 0.65 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr15_-_51535208 0.64 ENST00000405913.3
ENST00000559878.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr12_-_54758251 0.64 ENST00000267015.3
ENST00000551809.1
GPR84
G protein-coupled receptor 84
chr19_+_54496132 0.64 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr5_-_110062349 0.63 ENST00000511883.2
ENST00000455884.2
TMEM232
transmembrane protein 232
chr2_-_89161064 0.62 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr2_+_66662690 0.60 ENST00000488550.1
MEIS1
Meis homeobox 1
chr2_+_66662510 0.60 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr7_-_38293030 0.59 ENST00000390333.1
TRGJ2
T cell receptor gamma joining 2
chr2_+_120303717 0.59 ENST00000594371.1
PCDP1
Primary ciliary dyskinesia protein 1
chr9_+_2159850 0.59 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_101293687 0.58 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr2_+_202937972 0.57 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr19_-_10687983 0.56 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr5_-_110062384 0.56 ENST00000429839.2
TMEM232
transmembrane protein 232
chr11_+_57310114 0.53 ENST00000527972.1
ENST00000399154.2
SMTNL1
smoothelin-like 1
chrX_+_53449839 0.53 ENST00000457095.1
RIBC1
RIB43A domain with coiled-coils 1
chr16_-_53737795 0.53 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr12_+_8276495 0.52 ENST00000546339.1
CLEC4A
C-type lectin domain family 4, member A
chr2_+_27799389 0.51 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr5_-_90679145 0.51 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chrX_+_53449805 0.50 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr7_+_66800928 0.49 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr6_+_21593972 0.49 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr5_-_35230569 0.49 ENST00000515839.1
PRLR
prolactin receptor
chr17_-_47287928 0.48 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_-_228613026 0.48 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr17_-_73781567 0.48 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr11_+_36397528 0.48 ENST00000311599.5
ENST00000378867.3
PRR5L
proline rich 5 like
chr2_+_1418154 0.48 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr7_+_102553430 0.47 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr1_+_164528866 0.47 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr12_+_100867733 0.46 ENST00000546380.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr17_-_79895097 0.46 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr6_+_45296391 0.46 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr17_-_79481666 0.46 ENST00000575659.1
ACTG1
actin, gamma 1
chr3_-_99833333 0.45 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr2_-_99757606 0.45 ENST00000542655.1
TSGA10
testis specific, 10
chr2_+_233390863 0.44 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr18_+_56532100 0.44 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr17_+_19281787 0.44 ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7
chr8_+_11291429 0.44 ENST00000533578.1
C8orf12
chromosome 8 open reading frame 12
chr7_+_144015218 0.44 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr11_-_5323226 0.44 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chrX_+_133507389 0.44 ENST00000370800.4
PHF6
PHD finger protein 6
chrX_-_133792480 0.43 ENST00000359237.4
PLAC1
placenta-specific 1
chr11_-_10920714 0.42 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr2_+_217082311 0.42 ENST00000597904.1
RP11-566E18.3
RP11-566E18.3
chr10_+_17272608 0.42 ENST00000421459.2
VIM
vimentin
chr19_-_49140692 0.41 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr20_-_43248126 0.41 ENST00000597250.1
Z97053.1
Uncharacterized protein
chr11_-_72432950 0.41 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr16_+_67360712 0.41 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr7_-_17500294 0.41 ENST00000439046.1
AC019117.2
AC019117.2
chrX_+_27608490 0.41 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr9_-_93925369 0.40 ENST00000457976.1
RP11-305L7.3
RP11-305L7.3
chr19_-_49140609 0.40 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr17_-_19281203 0.39 ENST00000487415.2
B9D1
B9 protein domain 1
chr11_-_72433346 0.39 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_+_47448102 0.39 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr1_+_59250815 0.39 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr2_-_61389240 0.39 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr7_+_112063192 0.38 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr1_+_164528616 0.38 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr14_-_64108125 0.38 ENST00000267522.3
WDR89
WD repeat domain 89
chr18_+_56532053 0.38 ENST00000592452.1
ZNF532
zinc finger protein 532
chr6_+_45296048 0.38 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr12_+_71833550 0.38 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chrX_+_84498989 0.38 ENST00000395402.1
ZNF711
zinc finger protein 711
chr14_-_69262916 0.38 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr11_-_64703354 0.37 ENST00000532246.1
ENST00000279168.2
GPHA2
glycoprotein hormone alpha 2
chr21_-_36421401 0.37 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr8_-_145642267 0.37 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_157014865 0.37 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr3_-_48632593 0.37 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chrX_+_53449887 0.37 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chrX_+_84499081 0.36 ENST00000276123.3
ZNF711
zinc finger protein 711
chr12_+_8276433 0.36 ENST00000345999.3
ENST00000352620.3
ENST00000360500.3
CLEC4A
C-type lectin domain family 4, member A
chr9_+_71939488 0.36 ENST00000455972.1
FAM189A2
family with sequence similarity 189, member A2
chr12_-_113658892 0.36 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr15_-_100038578 0.36 ENST00000595415.1
AC015660.1
HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
chr18_+_20494078 0.36 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr3_-_71353892 0.36 ENST00000484350.1
FOXP1
forkhead box P1
chrX_+_133507327 0.36 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHF6
PHD finger protein 6
chr17_-_63557309 0.35 ENST00000580513.1
AXIN2
axin 2
chr1_+_36772691 0.35 ENST00000312808.4
ENST00000505871.1
SH3D21
SH3 domain containing 21
chr5_-_150284532 0.35 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
ZNF300
zinc finger protein 300
chr11_-_8892900 0.35 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5
suppression of tumorigenicity 5
chr17_-_39780634 0.35 ENST00000577817.2
KRT17
keratin 17
chr17_-_63557759 0.35 ENST00000307078.5
AXIN2
axin 2
chr15_+_42131011 0.34 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chrX_+_84499038 0.34 ENST00000373165.3
ZNF711
zinc finger protein 711
chrX_+_133507283 0.34 ENST00000370803.3
PHF6
PHD finger protein 6
chr22_+_31518938 0.34 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr8_-_145641864 0.34 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr5_-_150284351 0.34 ENST00000427179.1
ZNF300
zinc finger protein 300
chr17_+_73780852 0.34 ENST00000589666.1
UNK
unkempt family zinc finger
chr5_-_149465990 0.34 ENST00000543093.1
CSF1R
colony stimulating factor 1 receptor
chr16_+_50308028 0.34 ENST00000566761.2
ADCY7
adenylate cyclase 7
chr2_-_219696511 0.34 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr1_+_104104379 0.34 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr12_+_110011571 0.34 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr15_-_81195510 0.33 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr5_-_111091948 0.33 ENST00000447165.2
NREP
neuronal regeneration related protein
chr11_-_94964354 0.33 ENST00000536441.1
SESN3
sestrin 3
chr12_+_8276224 0.33 ENST00000229332.5
CLEC4A
C-type lectin domain family 4, member A
chr15_-_70994612 0.33 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr15_+_75487984 0.33 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chr6_+_143772060 0.33 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr14_-_64108537 0.32 ENST00000554717.1
ENST00000394942.2
WDR89
WD repeat domain 89
chr4_+_89299994 0.32 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr8_-_49834299 0.32 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr2_-_207078154 0.32 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr6_+_143771934 0.32 ENST00000367592.1
PEX3
peroxisomal biogenesis factor 3
chr1_-_49242553 0.32 ENST00000371833.3
BEND5
BEN domain containing 5
chr11_+_117049910 0.32 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr16_-_71518504 0.32 ENST00000565100.2
ZNF19
zinc finger protein 19
chr1_-_179834311 0.32 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr3_+_108321623 0.32 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr12_-_113658826 0.32 ENST00000546692.1
IQCD
IQ motif containing D
chr21_+_17566643 0.31 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr3_+_149689066 0.31 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr4_-_89951028 0.31 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr7_-_91764108 0.31 ENST00000450723.1
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr1_+_150337144 0.31 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr13_-_30683005 0.31 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr11_+_117049854 0.31 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr2_+_176987088 0.31 ENST00000249499.6
HOXD9
homeobox D9
chr15_+_99433570 0.31 ENST00000558898.1
IGF1R
insulin-like growth factor 1 receptor
chr16_+_4838412 0.31 ENST00000589327.1
SMIM22
small integral membrane protein 22
chr6_-_44400720 0.31 ENST00000595057.1
AL133262.1
AL133262.1
chr12_-_65090329 0.30 ENST00000594966.1
AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
chr2_-_207078086 0.30 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr17_-_46262541 0.30 ENST00000579336.1
SKAP1
src kinase associated phosphoprotein 1
chr14_+_59100774 0.30 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr15_+_84115868 0.30 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 2.1 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.5 1.4 GO:0035566 regulation of metanephros size(GO:0035566)
0.3 0.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 1.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 0.9 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 2.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.3 1.0 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.2 0.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 1.0 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.6 GO:0070377 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.2 0.6 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.5 GO:0048174 negative regulation of short-term neuronal synaptic plasticity(GO:0048174)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.6 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.8 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 0.5 GO:0035910 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 1.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.7 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.4 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.9 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.6 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 1.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.8 GO:0015705 iodide transport(GO:0015705)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.0 1.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 1.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.2 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 1.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 2.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.8 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.3 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 1.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0061198 negative regulation of MHC class II biosynthetic process(GO:0045347) fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:2000468 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 2.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 2.4 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.1 3.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 6.6 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 2.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 1.8 GO:0031904 endosome lumen(GO:0031904)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 2.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 2.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.4 2.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 0.6 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.2 0.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.9 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.0 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 2.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.4 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 8.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 3.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER