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Illumina Body Map 2: averaged replicates

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Results for GFI1B

Z-value: 2.14

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Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
ENSG00000165702.8 growth factor independent 1B transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1Bhg19_v2_chr9_+_135854091_135854159-0.648.9e-05Click!

Activity profile of GFI1B motif

Sorted Z-values of GFI1B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_119184702 5.40 ENST00000549104.1
CTA-109P11.4
chr3_-_149688971 4.89 ENST00000498307.1
ENST00000489155.1
profilin 2
chr18_-_24445729 4.76 ENST00000383168.4
aquaporin 4
chr14_-_80677970 4.39 ENST00000438257.4
deiodinase, iodothyronine, type II
chr5_+_36608422 4.32 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_149689066 3.70 ENST00000593416.1
LOC646903 protein; Uncharacterized protein
chr17_+_70117153 3.59 ENST00000245479.2
SRY (sex determining region Y)-box 9
chr11_+_27076764 3.46 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_176828307 3.46 ENST00000513365.1
ENST00000513667.1
ENST00000503563.1
glycoprotein M6A
chr10_+_60936921 3.02 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr14_-_80677815 2.99 ENST00000557125.1
ENST00000555750.1
deiodinase, iodothyronine, type II
chr5_-_96478466 2.87 ENST00000274382.4
Lix1 homolog (chicken)
chr5_-_142077569 2.81 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr5_-_125930877 2.81 ENST00000510111.2
ENST00000509270.1
aldehyde dehydrogenase 7 family, member A1
chr5_+_36608280 2.73 ENST00000513646.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_220701740 2.63 ENST00000366917.4
MAP/microtubule affinity-regulating kinase 1
chr7_+_107110488 2.59 ENST00000304402.4
G protein-coupled receptor 22
chr1_+_220701456 2.56 ENST00000366918.4
ENST00000402574.1
MAP/microtubule affinity-regulating kinase 1
chr5_-_137475071 2.56 ENST00000265191.2
NME/NM23 family member 5
chr3_-_149688655 2.48 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr8_+_133931648 2.45 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr1_+_162602244 2.44 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr4_-_186696561 2.40 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
sorbin and SH3 domain containing 2
chr7_+_79765071 2.38 ENST00000457358.2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_+_123100620 2.30 ENST00000368444.3
fatty acid binding protein 7, brain
chr5_-_125930929 2.28 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr13_+_113623509 2.24 ENST00000535094.2
MCF.2 cell line derived transforming sequence-like
chr15_-_27184664 2.21 ENST00000541819.2
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr4_+_154125565 2.21 ENST00000338700.5
tripartite motif containing 2
chr6_-_56707943 2.18 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
dystonin
chr2_+_1418154 2.16 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr1_-_230513367 2.13 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr13_+_76413852 2.12 ENST00000533809.2
LIM domain 7
chr3_-_149688896 2.08 ENST00000239940.7
profilin 2
chr14_-_80678512 2.08 ENST00000553968.1
deiodinase, iodothyronine, type II
chr11_-_26743546 2.03 ENST00000280467.6
ENST00000396005.3
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_+_41362796 1.99 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr5_+_140261703 1.98 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr14_-_53417732 1.96 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
fermitin family member 2
chr19_+_18726786 1.96 ENST00000594709.1
transmembrane protein 59-like
chr19_-_55660561 1.94 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
troponin T type 1 (skeletal, slow)
chr9_+_12693336 1.89 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr3_-_179691866 1.85 ENST00000464614.1
ENST00000476138.1
ENST00000463761.1
peroxisomal biogenesis factor 5-like
chr19_-_35417716 1.83 ENST00000604333.1
CTC-523E23.8
chr6_-_56708459 1.81 ENST00000370788.2
dystonin
chr15_-_29745003 1.81 ENST00000560082.1
family with sequence similarity 189, member A1
chr19_-_44124019 1.77 ENST00000300811.3
zinc finger protein 428
chr3_+_35681728 1.77 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
cAMP-regulated phosphoprotein, 21kDa
chr12_-_28124903 1.76 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr12_-_82153087 1.75 ENST00000547623.1
ENST00000549396.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_+_62009653 1.75 ENST00000244926.3
secretoglobin, family 1D, member 2
chr4_+_76995855 1.75 ENST00000355810.4
ENST00000349321.3
ADP-ribosyltransferase 3
chr13_-_67802549 1.74 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr21_-_22175450 1.70 ENST00000435279.2
long intergenic non-protein coding RNA 320
chr19_+_3933085 1.69 ENST00000168977.2
ENST00000599576.1
nicotinamide riboside kinase 2
chr1_+_226736446 1.68 ENST00000366788.3
ENST00000366789.4
chromosome 1 open reading frame 95
chr12_+_48513009 1.67 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
phosphofructokinase, muscle
chr8_+_11291429 1.66 ENST00000533578.1
chromosome 8 open reading frame 12
chr6_+_12290586 1.66 ENST00000379375.5
endothelin 1
chr12_+_48513570 1.65 ENST00000551804.1
phosphofructokinase, muscle
chr5_-_96478457 1.64 ENST00000512378.1
Lix1 homolog (chicken)
chr4_-_186697044 1.63 ENST00000437304.2
sorbin and SH3 domain containing 2
chr12_+_124155652 1.62 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr6_+_46620676 1.60 ENST00000371347.5
ENST00000411689.2
solute carrier family 25, member 27
chr15_+_71228826 1.59 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr4_-_186732892 1.57 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
sorbin and SH3 domain containing 2
chr16_+_7560114 1.57 ENST00000570626.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_+_84499081 1.51 ENST00000276123.3
zinc finger protein 711
chr18_+_77905894 1.51 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
Uncharacterized protein
chr9_-_73736511 1.50 ENST00000377110.3
ENST00000377111.2
transient receptor potential cation channel, subfamily M, member 3
chr2_+_166326157 1.50 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr5_+_57878859 1.50 ENST00000282878.4
RAB3C, member RAS oncogene family
chr3_+_173116225 1.50 ENST00000457714.1
neuroligin 1
chr4_+_48807155 1.48 ENST00000504654.1
OCIA domain containing 1
chr3_+_159481791 1.47 ENST00000460298.1
IQCJ-SCHIP1 readthrough
chr7_-_14029515 1.47 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr14_-_93214988 1.47 ENST00000557434.1
ENST00000393218.2
ENST00000334869.4
legumain
chr21_-_22175341 1.46 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
long intergenic non-protein coding RNA 320
chr1_+_204839959 1.45 ENST00000404076.1
neurofascin
chr6_-_123958141 1.44 ENST00000334268.4
triadin
chr14_-_93214915 1.44 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
legumain
chr19_-_44123734 1.44 ENST00000598676.1
zinc finger protein 428
chrX_+_84498989 1.43 ENST00000395402.1
zinc finger protein 711
chr1_+_202091980 1.43 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr15_+_48051920 1.43 ENST00000559196.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr4_-_186696636 1.42 ENST00000444771.1
sorbin and SH3 domain containing 2
chr12_+_117176090 1.42 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
ring finger protein, transmembrane 2
chrX_+_84499038 1.41 ENST00000373165.3
zinc finger protein 711
chr16_-_75301886 1.40 ENST00000393422.2
breast cancer anti-estrogen resistance 1
chr7_-_108097144 1.39 ENST00000418239.1
neuronal cell adhesion molecule
chr18_+_11857439 1.39 ENST00000602628.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr3_+_121311966 1.39 ENST00000338040.4
F-box protein 40
chr5_-_124080203 1.37 ENST00000504926.1
zinc finger protein 608
chr1_+_210406121 1.37 ENST00000367012.3
SERTA domain containing 4
chr12_+_117176113 1.36 ENST00000319176.7
ring finger protein, transmembrane 2
chr10_+_24498060 1.36 ENST00000376454.3
ENST00000376452.3
KIAA1217
chr2_+_105050794 1.35 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr6_+_46620705 1.35 ENST00000452689.2
solute carrier family 25, member 27
chr2_-_77749474 1.35 ENST00000409093.1
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr1_+_176432298 1.34 ENST00000367661.3
ENST00000367662.3
pappalysin 2
chr1_+_15272271 1.34 ENST00000400797.3
kazrin, periplakin interacting protein
chr1_+_162601774 1.32 ENST00000415555.1
discoidin domain receptor tyrosine kinase 2
chr2_-_77749446 1.32 ENST00000409911.1
leucine rich repeat transmembrane neuronal 4
chr7_-_108096765 1.31 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr20_+_58179582 1.30 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr15_-_83378638 1.29 ENST00000261722.3
adaptor-related protein complex 3, beta 2 subunit
chr17_+_46131843 1.29 ENST00000577411.1
nuclear factor, erythroid 2-like 1
chr12_-_118406028 1.28 ENST00000425217.1
kinase suppressor of ras 2
chrX_-_71933888 1.28 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
phosphorylase kinase, alpha 1 (muscle)
chr1_+_164528866 1.28 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr2_+_86116396 1.26 ENST00000455121.3
AC105053.4
chr15_+_48413169 1.26 ENST00000341459.3
ENST00000482911.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr15_+_48413211 1.25 ENST00000449382.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr6_-_123957942 1.25 ENST00000398178.3
triadin
chr6_-_123958051 1.25 ENST00000546248.1
triadin
chr7_-_108096822 1.24 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr18_-_30050395 1.24 ENST00000269209.6
ENST00000399218.4
GRB2 associated, regulator of MAPK1
chr4_-_186696425 1.23 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr4_-_186696515 1.22 ENST00000456596.1
ENST00000414724.1
sorbin and SH3 domain containing 2
chr14_+_29236269 1.22 ENST00000313071.4
forkhead box G1
chr18_+_56532053 1.22 ENST00000592452.1
zinc finger protein 532
chr6_+_146348782 1.21 ENST00000361719.2
ENST00000392299.2
glutamate receptor, metabotropic 1
chr2_+_158733088 1.18 ENST00000605860.1
uridine phosphorylase 2
chr3_-_100551141 1.18 ENST00000478235.1
ENST00000471901.1
ABI family, member 3 (NESH) binding protein
chr1_+_202385953 1.17 ENST00000466968.1
protein phosphatase 1, regulatory subunit 12B
chr7_-_37382360 1.17 ENST00000455119.1
engulfment and cell motility 1
chr6_-_123958111 1.16 ENST00000542443.1
triadin
chr1_-_49242553 1.16 ENST00000371833.3
BEN domain containing 5
chr8_+_75736761 1.15 ENST00000260113.2
peptidase inhibitor 15
chr18_+_56532100 1.15 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr12_+_72667203 1.14 ENST00000547300.1
thyrotropin-releasing hormone degrading enzyme
chr7_-_142630820 1.14 ENST00000442623.1
ENST00000265310.1
transient receptor potential cation channel, subfamily V, member 5
chr10_+_52152766 1.14 ENST00000596442.1
Uncharacterized protein
chr22_+_38864041 1.13 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_-_176733377 1.13 ENST00000505375.1
glycoprotein M6A
chr21_+_35014706 1.12 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
intersectin 1 (SH3 domain protein)
chr1_+_45792541 1.12 ENST00000334815.3
4-hydroxyphenylpyruvate dioxygenase-like
chr1_-_19615744 1.12 ENST00000361640.4
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr7_-_86595190 1.11 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr1_+_156611960 1.09 ENST00000361588.5
brevican
chr3_+_119814070 1.09 ENST00000469070.1
RP11-18H7.1
chr2_+_176987088 1.08 ENST00000249499.6
homeobox D9
chr5_+_140529630 1.08 ENST00000543635.1
protocadherin beta 6
chr12_-_59314246 1.07 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr3_+_184055240 1.06 ENST00000383847.2
family with sequence similarity 131, member A
chr11_+_119056178 1.06 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZ domain containing 3
chr11_-_40315640 1.06 ENST00000278198.2
leucine rich repeat containing 4C
chr1_-_190443931 1.05 ENST00000445957.2
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_186733119 1.04 ENST00000419063.1
sorbin and SH3 domain containing 2
chr11_+_5618029 1.03 ENST00000515022.1
ENST00000506134.1
tripartite motif containing 6
chr3_-_49466686 1.03 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr2_+_162272605 1.03 ENST00000389554.3
T-box, brain, 1
chr10_+_124221036 1.03 ENST00000368984.3
HtrA serine peptidase 1
chr15_+_32933866 1.01 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
secretogranin V (7B2 protein)
chr4_-_100575781 1.01 ENST00000511828.1
Protein LOC285556
chr13_+_98795664 1.00 ENST00000376581.5
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_164528616 1.00 ENST00000340699.3
pre-B-cell leukemia homeobox 1
chr10_+_71211212 1.00 ENST00000373290.2
tetraspanin 15
chr17_-_79895154 0.99 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
pyrroline-5-carboxylate reductase 1
chr6_-_93433538 0.99 ENST00000404689.2
RP11-127B16.1
chr3_-_158450231 0.98 ENST00000479756.1
retinoic acid receptor responder (tazarotene induced) 1
chr4_-_104640973 0.98 ENST00000304883.2
tachykinin receptor 3
chr18_-_35145728 0.98 ENST00000361795.5
ENST00000603232.1
CUGBP, Elav-like family member 4
chr19_-_51141196 0.97 ENST00000338916.4
synaptotagmin III
chr10_+_45455207 0.97 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
Ras association (RalGDS/AF-6) domain family member 4
chr12_+_32638897 0.96 ENST00000531134.1
FYVE, RhoGEF and PH domain containing 4
chr7_+_55086794 0.96 ENST00000275493.2
ENST00000442591.1
epidermal growth factor receptor
chr2_+_35056422 0.96 ENST00000592523.1
ENST00000588944.1
ENST00000585391.1
ENST00000591221.1
ENST00000586769.1
ENST00000588650.1
AC012593.1
chr17_-_57604227 0.96 ENST00000584262.1
RP11-567L7.6
chr19_+_2867325 0.96 ENST00000307635.2
ENST00000586426.1
zinc finger protein 556
chr9_-_14180778 0.95 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr19_+_3880581 0.95 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ataxia, cerebellar, Cayman type
chr17_-_37764128 0.94 ENST00000302584.4
neuronal differentiation 2
chr20_+_36974759 0.94 ENST00000217407.2
lipopolysaccharide binding protein
chr8_+_62200509 0.94 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
clavesin 1
chr11_-_33774944 0.94 ENST00000532057.1
ENST00000531080.1
F-box protein 3
chr6_-_116601044 0.93 ENST00000368608.3
TSPY-like 1
chr6_+_146348810 0.91 ENST00000492807.2
glutamate receptor, metabotropic 1
chr17_+_46131912 0.91 ENST00000584634.1
ENST00000580050.1
nuclear factor, erythroid 2-like 1
chr10_-_49813090 0.90 ENST00000249601.4
Rho GTPase activating protein 22
chr5_+_3596168 0.90 ENST00000302006.3
iroquois homeobox 1
chr17_-_79895097 0.89 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr2_+_11752379 0.89 ENST00000396123.1
growth regulation by estrogen in breast cancer 1
chr5_+_15500280 0.88 ENST00000504595.1
F-box and leucine-rich repeat protein 7
chr11_+_101785727 0.88 ENST00000263468.8
KIAA1377
chr12_-_21910775 0.87 ENST00000539782.1
lactate dehydrogenase B
chr5_-_87974254 0.87 ENST00000506014.1
ENST00000502301.1
ENST00000513026.1
long intergenic non-protein coding RNA 461
chr6_+_26225354 0.87 ENST00000360408.1
histone cluster 1, H3e
chr19_-_10687907 0.87 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr15_+_69857515 0.86 ENST00000559477.1
RP11-279F6.1
chr17_-_57604200 0.86 ENST00000577478.1
RP11-567L7.6
chr17_-_50236039 0.85 ENST00000451037.2
carbonic anhydrase X
chr6_+_90192974 0.85 ENST00000520458.1
ankyrin repeat domain 6
chr3_-_165555200 0.85 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr7_-_100808394 0.84 ENST00000445482.2
VGF nerve growth factor inducible
chr14_-_103434869 0.84 ENST00000559043.1
CDC42 binding protein kinase beta (DMPK-like)
chr12_+_109273806 0.84 ENST00000228476.3
ENST00000547768.1
D-amino-acid oxidase
chr1_+_10290822 0.83 ENST00000377083.1
kinesin family member 1B
chr12_-_28125638 0.82 ENST00000545234.1
parathyroid hormone-like hormone
chr22_-_21360736 0.82 ENST00000547793.2
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
1.3 5.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.2 3.6 GO:0072034 primary prostatic bud elongation(GO:0060516) bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) renal vesicle induction(GO:0072034)
1.0 2.9 GO:0006624 vacuolar protein processing(GO:0006624)
0.6 7.0 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 1.9 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.6 9.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.6 2.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.6 3.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.6 1.7 GO:1902722 positive regulation of prolactin secretion(GO:1902722)
0.5 9.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 1.7 GO:0060584 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 1.5 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.4 1.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.0 GO:0097187 dentinogenesis(GO:0097187)
0.3 0.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.3 1.8 GO:0021764 amygdala development(GO:0021764)
0.3 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 0.8 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.3 5.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 4.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.3 1.9 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.3 3.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.3 1.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 1.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.2 0.7 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.2 1.2 GO:0046108 uridine metabolic process(GO:0046108)
0.2 4.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.9 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.2 0.7 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 0.9 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 3.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.2 1.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 2.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 0.8 GO:1904647 response to rotenone(GO:1904647)
0.2 10.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.2 0.9 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 2.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2 2.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 2.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 0.5 GO:0061055 myotome development(GO:0061055)
0.2 2.4 GO:0015705 iodide transport(GO:0015705)
0.2 1.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 5.5 GO:0006833 water transport(GO:0006833)
0.2 1.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.2 1.6 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.6 GO:2000410 tolerance induction dependent upon immune response(GO:0002461) regulation of thymocyte migration(GO:2000410)
0.1 2.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.6 GO:0090290 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 5.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 1.7 GO:0051451 myoblast migration(GO:0051451)
0.1 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.7 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217) hyperosmotic salinity response(GO:0042538)
0.1 2.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.9 GO:0010265 SCF complex assembly(GO:0010265)
0.1 2.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 2.7 GO:0060134 prepulse inhibition(GO:0060134)
0.1 4.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 2.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.6 GO:0072554 blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.4 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.2 GO:0003186 tricuspid valve morphogenesis(GO:0003186)
0.1 0.7 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.5 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 4.5 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 2.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.7 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.1 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.1 GO:0035809 regulation of urine volume(GO:0035809)
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 4.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 1.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.9 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.8 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 1.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.4 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.9 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 2.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 6.0 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 1.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.7 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 4.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.0 0.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 1.9 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 2.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.3 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0031673 H zone(GO:0031673)
0.6 1.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.5 2.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 2.9 GO:0036021 endolysosome lumen(GO:0036021)
0.4 3.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 5.1 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 0.6 GO:0032302 MutSbeta complex(GO:0032302)
0.2 4.6 GO:0043194 axon initial segment(GO:0043194)
0.1 0.6 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 3.0 GO:0036038 MKS complex(GO:0036038)
0.1 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.9 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.5 GO:0097386 glial cell projection(GO:0097386)
0.1 1.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 9.5 GO:0043195 terminal bouton(GO:0043195)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 4.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 4.0 GO:0099738 cell cortex region(GO:0099738)
0.0 2.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 11.3 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.6 GO:0042641 actomyosin(GO:0042641)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 3.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.7 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 13.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.1 GO:0005874 microtubule(GO:0005874)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 2.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0030120 vesicle coat(GO:0030120)
0.0 4.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 8.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.3 GO:0098793 presynapse(GO:0098793)
0.0 0.6 GO:0030118 clathrin coat(GO:0030118)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.9 3.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.7 7.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.9 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.4 1.7 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.4 1.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 3.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 1.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 2.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 3.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 4.8 GO:0015250 water channel activity(GO:0015250)
0.3 1.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 3.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 10.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 1.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 2.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 0.6 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 0.6 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2 1.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 5.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 4.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.8 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.2 1.4 GO:0042835 BRE binding(GO:0042835)
0.2 0.5 GO:0032090 Pyrin domain binding(GO:0032090)
0.2 2.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.8 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 2.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 9.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 5.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 1.9 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 2.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.7 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 2.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 4.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.7 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.2 GO:0042731 PH domain binding(GO:0042731)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 2.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.3 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.5 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.9 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.5 GO:0031489 myosin V binding(GO:0031489)
0.0 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 7.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0003682 chromatin binding(GO:0003682)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 2.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 3.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 5.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 4.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 5.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 1.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 8.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 4.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 3.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.6 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 4.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 2.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 9.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 3.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 4.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 7.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 7.7 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion