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Illumina Body Map 2: averaged replicates
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Results for GGAAUGU
Z-value: 2.07
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miRNA associated with seed GGAAUGU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_102106829 Show fit | 2.73 |
ENST00000370355.2
|
stearoyl-CoA desaturase (delta-9-desaturase) |
|
| chr15_+_39873268 Show fit | 2.70 |
ENST00000397591.2
ENST00000260356.5 |
thrombospondin 1 |
|
| chr17_-_46657473 Show fit | 2.18 |
ENST00000332503.5
|
homeobox B4 |
|
| chr4_-_111119804 Show fit | 2.08 |
ENST00000394607.3
ENST00000302274.3 |
ELOVL fatty acid elongase 6 |
|
| chr11_+_128563652 Show fit | 1.90 |
ENST00000527786.2
|
Fli-1 proto-oncogene, ETS transcription factor |
|
| chr1_+_26606608 Show fit | 1.89 |
ENST00000319041.6
|
SH3 domain binding glutamic acid-rich protein like 3 |
|
| chr12_+_12764773 Show fit | 1.87 |
ENST00000228865.2
|
cAMP responsive element binding protein-like 2 |
|
| chr14_+_20937538 Show fit | 1.86 |
ENST00000361505.5
ENST00000553591.1 |
purine nucleoside phosphorylase |
|
| chr7_-_5570229 Show fit | 1.84 |
ENST00000331789.5
|
actin, beta |
|
| chr7_+_8008418 Show fit | 1.83 |
ENST00000223145.5
|
glucocorticoid induced transcript 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGAAUGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.2 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 0.0 | 3.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.9 | 2.7 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.9 | 2.7 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) |
| 0.2 | 2.7 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.1 | 2.6 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.0 | 2.4 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.2 | 2.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 2.2 | GO:0046326 | positive regulation of glucose import(GO:0046326) |
| 0.3 | 2.1 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 4.1 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 3.5 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 3.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 2.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 2.4 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 2.3 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 2.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 2.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 2.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.8 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 4.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 3.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 2.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.5 | 2.7 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.3 | 2.7 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 2.3 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.2 | 2.1 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.6 | 1.9 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.1 | 1.9 | GO:0030957 | Tat protein binding(GO:0030957) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.1 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 4.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 3.2 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 2.9 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 2.6 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 2.4 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 2.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 2.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 4.0 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.0 | 3.9 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.0 | 3.2 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 3.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 2.8 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 2.7 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 2.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 2.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 2.4 | REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |