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Illumina Body Map 2: averaged replicates

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Results for GGCAGUG

Z-value: 2.07

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miRNA associated with seed GGCAGUG

NamemiRBASE accession
hsa-miR-34a-5p
MIMAT0000255
hsa-miR-34c-5p
MIMAT0000686
hsa-miR-449a
MIMAT0001541
hsa-miR-449b-5p
MIMAT0003327

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_175223313 8.65 ENST00000359546.4
CPLX2
complexin 2
chr10_+_105036909 7.72 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr1_+_205012293 7.14 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr20_+_10199468 6.16 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr12_+_79258547 5.96 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_181452678 4.63 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr16_+_56225248 4.56 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr13_-_25746416 4.53 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr1_-_151688528 4.09 ENST00000290585.4
CELF3
CUGBP, Elav-like family member 3
chr5_+_110559784 4.04 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr18_+_55018044 3.92 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_-_6202291 3.87 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chrX_-_151619746 3.86 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr6_+_96463840 3.83 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr14_+_29234870 3.54 ENST00000382535.3
FOXG1
forkhead box G1
chr10_+_25463951 3.54 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr9_+_34958254 3.47 ENST00000242315.3
KIAA1045
KIAA1045
chr16_+_87636474 3.28 ENST00000284262.2
JPH3
junctophilin 3
chr18_-_70535177 3.25 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr10_+_95517566 3.22 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr20_+_37434329 3.01 ENST00000299824.1
ENST00000373331.2
PPP1R16B
protein phosphatase 1, regulatory subunit 16B
chr12_-_14133053 3.00 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr9_+_126773880 2.99 ENST00000373615.4
LHX2
LIM homeobox 2
chr7_+_94285637 2.99 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr17_-_41977964 2.95 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr4_+_47033345 2.92 ENST00000295454.3
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr2_-_166930131 2.89 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr5_-_11904152 2.86 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr15_+_59730348 2.85 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr12_-_58135903 2.83 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr19_-_55954230 2.82 ENST00000376325.4
SHISA7
shisa family member 7
chr17_-_31620006 2.74 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr16_+_66878814 2.74 ENST00000394069.3
CA7
carbonic anhydrase VII
chr8_-_60031762 2.66 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr3_-_179754706 2.66 ENST00000465751.1
ENST00000467460.1
PEX5L
peroxisomal biogenesis factor 5-like
chr22_+_26825213 2.63 ENST00000215906.5
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr1_+_110693103 2.61 ENST00000331565.4
SLC6A17
solute carrier family 6 (neutral amino acid transporter), member 17
chr3_+_113251143 2.61 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr1_+_162039558 2.56 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr8_-_133493200 2.56 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr9_-_101471479 2.54 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_110500905 2.52 ENST00000392587.2
WASF1
WAS protein family, member 1
chr15_-_44486632 2.47 ENST00000484674.1
FRMD5
FERM domain containing 5
chr11_-_118047376 2.47 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr17_+_29718642 2.47 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_-_41131326 2.47 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr17_-_37382105 2.40 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr5_+_143584814 2.35 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr13_-_27334879 2.33 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr8_+_28174649 2.32 ENST00000301908.3
PNOC
prepronociceptin
chr11_+_7273181 2.29 ENST00000318881.6
SYT9
synaptotagmin IX
chr17_-_37764128 2.29 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr7_+_107110488 2.28 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr2_+_105471969 2.24 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr18_+_67068228 2.23 ENST00000382713.5
DOK6
docking protein 6
chr20_+_42875887 2.23 ENST00000342560.5
GDAP1L1
ganglioside induced differentiation associated protein 1-like 1
chr10_-_62149433 2.21 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_134281812 2.12 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr2_+_16080659 2.08 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr22_-_37099555 2.01 ENST00000300105.6
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr15_+_52043758 2.00 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr11_-_64410787 1.99 ENST00000301894.2
NRXN2
neurexin 2
chr3_+_183948161 1.99 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr7_+_145813453 1.98 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr4_+_99182593 1.97 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1GDS1
RAP1, GTP-GDP dissociation stimulator 1
chr22_+_42372931 1.93 ENST00000328414.8
ENST00000396425.3
SEPT3
septin 3
chr1_+_84543734 1.92 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_11324273 1.91 ENST00000284486.4
FAM167A
family with sequence similarity 167, member A
chr3_+_39851094 1.89 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr17_+_42836329 1.89 ENST00000200557.6
ADAM11
ADAM metallopeptidase domain 11
chr7_+_87563458 1.87 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chrX_+_113818545 1.87 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr17_+_40834580 1.74 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr11_+_107461948 1.72 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr15_+_54305101 1.70 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr17_-_1083078 1.67 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr11_+_56949221 1.66 ENST00000497933.1
LRRC55
leucine rich repeat containing 55
chr9_-_122131696 1.64 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr3_-_172428959 1.62 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
NCEH1
neutral cholesterol ester hydrolase 1
chr10_-_135238076 1.61 ENST00000414069.2
SPRN
shadow of prion protein homolog (zebrafish)
chr2_-_40679186 1.59 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr8_+_11141925 1.53 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr7_+_20370746 1.52 ENST00000222573.4
ITGB8
integrin, beta 8
chr13_-_100624012 1.52 ENST00000267294.4
ZIC5
Zic family member 5
chr11_-_9025541 1.51 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr9_+_103204553 1.51 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_+_107712173 1.50 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr19_-_49015050 1.37 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr11_+_92085262 1.36 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr17_-_8066250 1.34 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr19_-_44143939 1.33 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr11_-_119599794 1.32 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr1_+_31769836 1.31 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17
zinc finger, CCHC domain containing 17
chr14_-_99737565 1.28 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr10_+_134000404 1.27 ENST00000338492.4
ENST00000368629.1
DPYSL4
dihydropyrimidinase-like 4
chr1_-_205326022 1.26 ENST00000367155.3
KLHDC8A
kelch domain containing 8A
chr15_+_43803143 1.26 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr14_-_89259080 1.24 ENST00000554922.1
ENST00000352093.5
EML5
echinoderm microtubule associated protein like 5
chr2_+_73144604 1.21 ENST00000258106.6
EMX1
empty spiracles homeobox 1
chr19_+_18794470 1.17 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr4_+_113970772 1.16 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr3_-_190580404 1.13 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr2_-_70995307 1.12 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2
adducin 2 (beta)
chr7_-_112727774 1.12 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr7_-_71801980 1.11 ENST00000329008.5
CALN1
calneuron 1
chr5_+_63802109 1.11 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr17_+_43971643 1.09 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT
microtubule-associated protein tau
chr1_+_70034081 1.09 ENST00000310961.5
ENST00000370958.1
LRRC7
leucine rich repeat containing 7
chr12_+_108525517 1.08 ENST00000332082.4
WSCD2
WSC domain containing 2
chr9_+_103235365 1.07 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr17_+_61086917 1.06 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_163695128 1.04 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrX_-_119445263 1.03 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chr3_+_105085734 1.03 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr10_+_125425871 1.02 ENST00000284674.1
GPR26
G protein-coupled receptor 26
chr16_+_28303804 1.02 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chrX_-_110655391 1.01 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr16_-_4588822 1.01 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr14_-_77843390 0.97 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chrX_+_64708615 0.97 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr9_-_3525968 0.96 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr8_-_18871159 0.96 ENST00000327040.8
ENST00000440756.2
PSD3
pleckstrin and Sec7 domain containing 3
chr9_-_73736511 0.95 ENST00000377110.3
ENST00000377111.2
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_-_184870751 0.95 ENST00000335012.2
C3orf70
chromosome 3 open reading frame 70
chr9_+_115513003 0.94 ENST00000374232.3
SNX30
sorting nexin family member 30
chr2_+_74881355 0.92 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr15_+_79724858 0.92 ENST00000305428.3
KIAA1024
KIAA1024
chr4_-_175750364 0.91 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr8_+_76452097 0.91 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_240775447 0.90 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr8_-_81083731 0.90 ENST00000379096.5
TPD52
tumor protein D52
chr3_+_6902794 0.89 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
GRM7
glutamate receptor, metabotropic 7
chrX_+_23352133 0.88 ENST00000379361.4
PTCHD1
patched domain containing 1
chr17_-_71640227 0.86 ENST00000388726.3
ENST00000392650.3
SDK2
sidekick cell adhesion molecule 2
chr8_-_4852218 0.85 ENST00000400186.3
ENST00000602723.1
CSMD1
CUB and Sushi multiple domains 1
chr1_+_66797687 0.83 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_-_6007200 0.82 ENST00000244766.2
NRN1
neuritin 1
chr2_+_24272543 0.80 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr8_-_119634141 0.78 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12
sterile alpha motif domain containing 12
chr4_-_109089573 0.78 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr5_+_142149955 0.78 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr12_+_10331605 0.76 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr21_+_45138941 0.74 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr17_-_61777459 0.74 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr11_-_22851367 0.73 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr11_+_35684288 0.73 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr12_+_74931551 0.70 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr1_+_155247207 0.69 ENST00000368358.3
HCN3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr2_+_239335449 0.68 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr3_+_50712672 0.67 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr8_-_92053212 0.67 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr8_-_95908902 0.66 ENST00000520509.1
CCNE2
cyclin E2
chr14_-_68162464 0.64 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr11_+_46354455 0.64 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr20_+_43029911 0.64 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr8_-_96281419 0.63 ENST00000286688.5
C8orf37
chromosome 8 open reading frame 37
chr7_+_28452130 0.63 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr16_+_83841448 0.63 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr16_-_17564738 0.63 ENST00000261381.6
XYLT1
xylosyltransferase I
chr2_-_100721178 0.61 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr7_-_143059845 0.59 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr1_+_219347186 0.58 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr1_-_21978312 0.57 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr3_+_113666748 0.57 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr1_+_160175117 0.57 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr7_-_73133959 0.56 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chr10_+_43572475 0.56 ENST00000355710.3
ENST00000498820.1
ENST00000340058.5
RET
ret proto-oncogene
chr4_+_144257915 0.56 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr10_+_1095416 0.55 ENST00000358220.1
WDR37
WD repeat domain 37
chr3_-_123168551 0.54 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr5_-_149492904 0.54 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr16_+_81069433 0.53 ENST00000299575.4
ATMIN
ATM interactor
chr9_-_104249319 0.53 ENST00000374847.1
TMEM246
transmembrane protein 246
chr1_-_91487013 0.53 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr2_-_200322723 0.51 ENST00000417098.1
SATB2
SATB homeobox 2
chr9_-_123639600 0.50 ENST00000373896.3
PHF19
PHD finger protein 19
chr5_+_180650271 0.50 ENST00000351937.5
ENST00000315073.5
TRIM41
tripartite motif containing 41
chr1_+_160085501 0.49 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr9_-_135996537 0.49 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr9_+_129677039 0.49 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr5_-_60458179 0.48 ENST00000507416.1
ENST00000339020.3
SMIM15
small integral membrane protein 15
chr12_+_49212514 0.48 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr5_-_138210977 0.47 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_+_33448593 0.46 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr10_-_88126224 0.45 ENST00000327946.7
GRID1
glutamate receptor, ionotropic, delta 1
chr15_-_41166414 0.44 ENST00000220507.4
RHOV
ras homolog family member V
chr19_+_7895074 0.43 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr22_-_29784519 0.43 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr21_-_34100244 0.42 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr3_+_11034403 0.41 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr4_+_170541660 0.41 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr7_-_102789629 0.41 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr2_-_68479614 0.40 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr17_+_15902694 0.39 ENST00000261647.5
ENST00000486880.2
TTC19
tetratricopeptide repeat domain 19
chr11_+_66025167 0.38 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2
kinesin light chain 2
chrX_-_118284542 0.37 ENST00000402510.2
KIAA1210
KIAA1210
chr3_+_38495333 0.36 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr12_+_49372251 0.36 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr2_+_191273052 0.36 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6
major facilitator superfamily domain containing 6
chr17_-_1928621 0.36 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0060168 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.5 6.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.3 4.0 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
1.0 3.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.0 6.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.9 2.6 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.8 2.5 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.7 2.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.7 3.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.6 7.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.5 2.7 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.5 1.9 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.5 2.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 2.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 1.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 5.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 2.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 1.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 2.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 2.5 GO:0046684 response to pyrethroid(GO:0046684)
0.3 8.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 2.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 2.6 GO:0015820 leucine transport(GO:0015820)
0.3 3.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.7 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 2.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 1.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 2.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 1.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 2.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 1.0 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 1.9 GO:0097338 response to clozapine(GO:0097338)
0.2 0.2 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.2 0.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.2 0.6 GO:0007497 posterior midgut development(GO:0007497)
0.2 4.1 GO:0030575 nuclear body organization(GO:0030575)
0.2 9.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.2 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 3.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 3.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.2 1.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.2 0.5 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.2 0.6 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 2.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 1.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.1 0.4 GO:0061184 Spemann organizer formation(GO:0060061) positive regulation of dermatome development(GO:0061184)
0.1 1.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.8 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 2.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.4 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 4.5 GO:0007398 ectoderm development(GO:0007398)
0.1 4.9 GO:0035640 exploration behavior(GO:0035640)
0.1 1.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 2.0 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.8 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 4.9 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 2.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 2.9 GO:0046710 GDP metabolic process(GO:0046710)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 2.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 3.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.9 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.7 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.9 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 2.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.5 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.9 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 3.2 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 1.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 2.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.6 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 2.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 2.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.1 10.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7 6.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.6 2.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 2.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 1.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.5 7.7 GO:0005883 neurofilament(GO:0005883)
0.4 5.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.4 14.8 GO:0033268 node of Ranvier(GO:0033268)
0.3 0.9 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.3 3.3 GO:0030314 junctional membrane complex(GO:0030314)
0.2 3.7 GO:0033010 paranodal junction(GO:0033010)
0.2 0.9 GO:0032279 asymmetric synapse(GO:0032279)
0.2 6.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.7 GO:0044305 calyx of Held(GO:0044305)
0.2 4.2 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 1.1 GO:0045298 tubulin complex(GO:0045298)
0.2 2.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.5 GO:0031209 SCAR complex(GO:0031209)
0.1 2.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 3.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:0016938 kinesin I complex(GO:0016938)
0.1 1.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 4.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 2.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0044306 neuron projection terminus(GO:0044306)
0.0 3.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.4 GO:0043679 axon terminus(GO:0043679)
0.0 3.2 GO:0043204 perikaryon(GO:0043204)
0.0 2.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 14.3 GO:0045202 synapse(GO:0045202)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 2.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 2.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.4 2.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 3.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 16.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 3.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 4.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 2.3 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 4.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 2.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 2.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 3.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 1.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.7 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.2 2.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 3.9 GO:0016594 glycine binding(GO:0016594)
0.2 0.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.6 GO:0004771 sterol esterase activity(GO:0004771)
0.2 4.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 4.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 2.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0070905 serine binding(GO:0070905)
0.1 1.9 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 3.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 3.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.5 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 2.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 3.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 7.7 GO:0043621 protein self-association(GO:0043621)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0003682 chromatin binding(GO:0003682)
0.1 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 4.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.4 GO:0016015 morphogen activity(GO:0016015)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 6.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 10.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 1.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855) chloride channel inhibitor activity(GO:0019869)
0.0 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 2.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.3 GO:0070888 E-box binding(GO:0070888)
0.0 4.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 2.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 8.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 2.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 6.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 6.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 3.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 6.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 7.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 11.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 6.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 4.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D