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Illumina Body Map 2: averaged replicates

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Results for GGCUCAG

Z-value: 0.98

Motif logo

miRNA associated with seed GGCUCAG

NamemiRBASE accession
MIMAT0000080

Activity profile of GGCUCAG motif

Sorted Z-values of GGCUCAG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_61788429 1.28 ENST00000332981.5
protein kinase C, eta
chr17_-_61777459 0.96 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr12_-_12674032 0.89 ENST00000298573.4
dual specificity phosphatase 16
chr12_+_54348618 0.89 ENST00000243103.3
homeobox C12
chr5_-_171615315 0.89 ENST00000176763.5
serine/threonine kinase 10
chr3_+_45636219 0.88 ENST00000273317.4
LIM domains containing 1
chr1_+_101702417 0.87 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr10_+_63661053 0.84 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr20_-_52210368 0.82 ENST00000371471.2
zinc finger protein 217
chr9_+_114659046 0.82 ENST00000374279.3
UDP-glucose ceramide glucosyltransferase
chr14_+_23305760 0.76 ENST00000311852.6
matrix metallopeptidase 14 (membrane-inserted)
chr5_-_140998616 0.76 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
diaphanous-related formin 1
chr15_+_91411810 0.75 ENST00000268171.3
furin (paired basic amino acid cleaving enzyme)
chr12_+_57916466 0.74 ENST00000355673.3
methyl-CpG binding domain protein 6
chr17_+_1958388 0.72 ENST00000399849.3
hypermethylated in cancer 1
chr5_-_131826457 0.69 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr11_-_6677018 0.69 ENST00000299441.3
dachsous cadherin-related 1
chr5_-_157002775 0.69 ENST00000257527.4
ADAM metallopeptidase domain 19
chr10_+_82213904 0.67 ENST00000429989.3
tetraspanin 14
chr10_-_33623564 0.66 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr12_+_53774423 0.64 ENST00000426431.2
Sp1 transcription factor
chr5_+_149887672 0.59 ENST00000261797.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_+_34431212 0.59 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr1_+_26126667 0.59 ENST00000361547.2
ENST00000354177.4
ENST00000374315.1
selenoprotein N, 1
chr3_-_197476560 0.57 ENST00000273582.5
KIAA0226
chr17_-_41739283 0.57 ENST00000393661.2
ENST00000318579.4
mesenchyme homeobox 1
chr1_-_200992827 0.57 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr3_-_87040233 0.57 ENST00000398399.2
vestigial like 3 (Drosophila)
chrX_-_48776292 0.57 ENST00000376509.4
pim-2 oncogene
chr1_-_236228403 0.56 ENST00000366595.3
nidogen 1
chr3_-_39195037 0.55 ENST00000273153.5
cysteine-serine-rich nuclear protein 1
chr9_-_117692697 0.54 ENST00000223795.2
tumor necrosis factor (ligand) superfamily, member 8
chr2_+_204571198 0.54 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28 molecule
chr22_-_37545972 0.53 ENST00000216223.5
interleukin 2 receptor, beta
chr19_+_1249869 0.52 ENST00000591446.2
midnolin
chr20_+_1875110 0.51 ENST00000400068.3
signal-regulatory protein alpha
chr10_-_76995769 0.51 ENST00000372538.3
catechol-O-methyltransferase domain containing 1
chr11_+_118754475 0.51 ENST00000292174.4
chemokine (C-X-C motif) receptor 5
chr12_-_68553512 0.49 ENST00000229135.3
interferon, gamma
chr15_+_65134088 0.48 ENST00000323544.4
ENST00000437723.1
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr5_-_149535421 0.47 ENST00000261799.4
platelet-derived growth factor receptor, beta polypeptide
chr10_-_95360983 0.46 ENST00000371464.3
retinol binding protein 4, plasma
chr20_+_34894247 0.46 ENST00000373913.3
discs, large (Drosophila) homolog-associated protein 4
chr10_+_20105157 0.46 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr1_+_165796753 0.46 ENST00000367879.4
uridine-cytidine kinase 2
chr17_-_42345487 0.45 ENST00000262418.6
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr8_-_10588010 0.45 ENST00000304501.1
SRY (sex determining region Y)-box 7
chr1_+_45265897 0.45 ENST00000372201.4
polo-like kinase 3
chr12_+_12870055 0.45 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr6_-_20212630 0.44 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
membrane bound O-acyltransferase domain containing 1
chr11_-_78052923 0.44 ENST00000340149.2
GRB2-associated binding protein 2
chr11_-_10590238 0.44 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr17_+_72733350 0.44 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37, member RAS oncogene family
chr12_+_68042495 0.44 ENST00000344096.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr11_+_75273101 0.43 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr2_-_69614373 0.43 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr16_-_67840442 0.42 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RAN binding protein 10
chr19_+_38810447 0.42 ENST00000263372.3
potassium channel, subfamily K, member 6
chrX_+_56259316 0.42 ENST00000468660.1
Kruppel-like factor 8
chr8_+_23104130 0.41 ENST00000313219.7
ENST00000519984.1
charged multivesicular body protein 7
chr2_+_201170703 0.41 ENST00000358677.5
spermatogenesis associated, serine-rich 2-like
chr17_+_19281034 0.41 ENST00000308406.5
ENST00000299612.7
mitogen-activated protein kinase 7
chr8_+_145064215 0.41 ENST00000313269.5
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr5_+_40679584 0.40 ENST00000302472.3
prostaglandin E receptor 4 (subtype EP4)
chr19_-_18632861 0.40 ENST00000262809.4
elongation factor RNA polymerase II
chr17_-_8055747 0.40 ENST00000317276.4
ENST00000581703.1
period circadian clock 1
chrX_+_57618269 0.40 ENST00000374888.1
zinc finger, X-linked, duplicated B
chr15_+_75074385 0.40 ENST00000220003.9
c-src tyrosine kinase
chr8_-_10697281 0.39 ENST00000524114.1
ENST00000553390.1
ENST00000554914.1
PIN2/TERF1 interacting, telomerase inhibitor 1
SRY (sex determining region Y)-box 7
Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7
chr5_-_149492904 0.39 ENST00000286301.3
ENST00000511344.1
colony stimulating factor 1 receptor
chr11_+_65837907 0.39 ENST00000320580.4
phosphofurin acidic cluster sorting protein 1
chr1_+_182992545 0.39 ENST00000258341.4
laminin, gamma 1 (formerly LAMB2)
chr7_+_138916231 0.39 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr19_-_15560730 0.38 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr12_+_121124599 0.38 ENST00000228506.3
malectin
chr7_+_5632436 0.38 ENST00000340250.6
ENST00000382361.3
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr17_-_27418537 0.38 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr12_+_69004619 0.38 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr20_-_36793774 0.37 ENST00000361475.2
transglutaminase 2
chr22_-_42466782 0.37 ENST00000396398.3
ENST00000403363.1
ENST00000402937.1
N-acetylgalactosaminidase, alpha-
chr6_+_35420091 0.36 ENST00000229769.2
Fanconi anemia, complementation group E
chr10_-_3827417 0.36 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr12_-_49504655 0.36 ENST00000551782.1
ENST00000267102.8
limb development membrane protein 1-like
chr4_+_55095264 0.36 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_130184555 0.36 ENST00000525842.1
zinc finger and BTB domain containing 44
chr1_+_185014496 0.36 ENST00000367510.3
ring finger protein 2
chr4_+_84457250 0.36 ENST00000395226.2
1-acylglycerol-3-phosphate O-acyltransferase 9
chr4_+_8271471 0.35 ENST00000307358.2
ENST00000382512.3
HtrA serine peptidase 3
chr12_-_125348448 0.35 ENST00000339570.5
scavenger receptor class B, member 1
chr19_-_47735918 0.35 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BCL2 binding component 3
chr1_-_120190396 0.33 ENST00000421812.2
zinc finger protein 697
chr7_-_74867509 0.33 ENST00000426327.3
GATS protein-like 2
chr12_+_53848505 0.33 ENST00000552819.1
ENST00000455667.3
poly(rC) binding protein 2
chr16_+_11762270 0.32 ENST00000329565.5
stannin
chr17_-_79885576 0.32 ENST00000574686.1
ENST00000357736.4
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chrX_+_70752917 0.32 ENST00000373719.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr8_-_28243934 0.32 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr2_+_206547215 0.32 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
neuropilin 2
chr18_+_72922710 0.32 ENST00000322038.5
teashirt zinc finger homeobox 1
chr6_+_106546808 0.30 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr1_+_156124162 0.30 ENST00000368282.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_50396978 0.30 ENST00000266025.3
transmembrane protein 115
chr1_-_180991978 0.29 ENST00000542060.1
ENST00000258301.5
syntaxin 6
chr5_-_112630598 0.29 ENST00000302475.4
mutated in colorectal cancers
chr9_-_130829588 0.29 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr20_+_51588873 0.29 ENST00000371497.5
teashirt zinc finger homeobox 2
chr19_-_46476791 0.29 ENST00000263257.5
neuro-oncological ventral antigen 2
chr16_-_68344830 0.28 ENST00000263997.6
solute carrier family 7, member 6 opposite strand
chr17_-_27507395 0.28 ENST00000354329.4
ENST00000527372.1
myosin XVIIIA
chr22_-_51066521 0.27 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
arylsulfatase A
chr5_+_65018017 0.27 ENST00000380985.5
ENST00000502464.1
neurolysin (metallopeptidase M3 family)
chr9_-_36276966 0.26 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr10_-_74114714 0.26 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DnaJ (Hsp40) homolog, subfamily B, member 12
chrX_+_107334895 0.26 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr16_+_67927147 0.26 ENST00000291041.5
protein serine kinase H1
chr19_+_45681997 0.26 ENST00000433642.2
biogenesis of lysosomal organelles complex-1, subunit 3
chr11_+_61447845 0.25 ENST00000257215.5
diacylglycerol lipase, alpha
chr8_-_95961578 0.25 ENST00000448464.2
ENST00000342697.4
tumor protein p53 inducible nuclear protein 1
chr6_+_35995488 0.25 ENST00000229795.3
mitogen-activated protein kinase 14
chr19_-_2456922 0.25 ENST00000582871.1
ENST00000325327.3
lamin B2
chr2_+_111878483 0.25 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2-like 11 (apoptosis facilitator)
chr22_+_39101728 0.25 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr5_+_154092396 0.25 ENST00000336314.4
La ribonucleoprotein domain family, member 1
chr2_+_43864387 0.24 ENST00000282406.4
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr11_-_118966167 0.24 ENST00000530167.1
H2A histone family, member X
chr22_+_21771656 0.24 ENST00000407464.2
hypermethylated in cancer 2
chr19_+_1026298 0.24 ENST00000263097.4
calponin 2
chr5_-_140053152 0.24 ENST00000542735.1
DND microRNA-mediated repression inhibitor 1
chr1_+_210001309 0.24 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chrX_+_49687216 0.24 ENST00000376088.3
chloride channel, voltage-sensitive 5
chr17_+_68165657 0.24 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_-_109605663 0.24 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr15_+_89631381 0.24 ENST00000352732.5
abhydrolase domain containing 2
chr12_+_124196865 0.23 ENST00000330342.3
ATPase, H+ transporting, lysosomal V0 subunit a2
chr6_+_37137939 0.23 ENST00000373509.5
pim-1 oncogene
chr7_+_155089486 0.22 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
insulin induced gene 1
chr11_+_62495997 0.22 ENST00000316461.4
tetratricopeptide repeat domain 9C
chr6_+_37225540 0.22 ENST00000373491.3
TBC1 domain family, member 22B
chr22_+_30279144 0.22 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
myotubularin related protein 3
chr3_-_122102065 0.22 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr1_+_118148556 0.22 ENST00000369448.3
family with sequence similarity 46, member C
chr3_+_88188254 0.22 ENST00000309495.5
zinc finger protein 654
chr14_-_75330537 0.22 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
prospero homeobox 2
chr1_-_47082495 0.21 ENST00000545730.1
ENST00000531769.1
ENST00000319928.3
MAP kinase interacting serine/threonine kinase 1
MOB kinase activator 3C
chr2_-_24149977 0.21 ENST00000238789.5
ATPase family, AAA domain containing 2B
chr1_-_153919128 0.21 ENST00000361217.4
DENN/MADD domain containing 4B
chr2_+_113931513 0.21 ENST00000245796.6
ENST00000441564.3
pleckstrin and Sec7 domain containing 4
chr15_+_42066632 0.21 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
mitogen-activated protein kinase binding protein 1
chr9_-_34589700 0.21 ENST00000351266.4
ciliary neurotrophic factor receptor
chr5_-_78281603 0.21 ENST00000264914.4
arylsulfatase B
chr5_-_172756506 0.21 ENST00000265087.4
stanniocalcin 2
chr16_-_4166186 0.21 ENST00000294016.3
adenylate cyclase 9
chr20_-_31071239 0.20 ENST00000359676.5
chromosome 20 open reading frame 112
chr12_-_498620 0.20 ENST00000399788.2
ENST00000382815.4
lysine (K)-specific demethylase 5A
chr10_-_128077024 0.20 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM metallopeptidase domain 12
chr1_+_27561007 0.19 ENST00000319394.3
WD and tetratricopeptide repeats 1
chr1_+_15943995 0.19 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr5_+_179921430 0.19 ENST00000393356.1
CCR4-NOT transcription complex, subunit 6
chr11_-_6624801 0.19 ENST00000534343.1
ENST00000254605.6
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr1_+_36348790 0.19 ENST00000373204.4
argonaute RISC catalytic component 1
chr2_+_102759199 0.19 ENST00000409288.1
ENST00000410023.1
interleukin 1 receptor, type I
chr6_-_44281043 0.19 ENST00000244571.4
alanyl-tRNA synthetase 2, mitochondrial
chr2_+_178257372 0.19 ENST00000264167.4
ENST00000409888.1
alkylglycerone phosphate synthase
chr4_+_39699664 0.19 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr3_+_51575596 0.19 ENST00000409535.2
RAD54-like 2 (S. cerevisiae)
chr12_-_53625958 0.19 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
retinoic acid receptor, gamma
chr1_-_169455169 0.19 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr1_+_172628154 0.19 ENST00000340030.3
ENST00000367721.2
Fas ligand (TNF superfamily, member 6)
chr8_-_134584152 0.19 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr10_-_60027642 0.18 ENST00000373935.3
inositol polyphosphate multikinase
chr7_-_100287071 0.18 ENST00000275732.5
GRB10 interacting GYF protein 1
chr22_+_42196666 0.18 ENST00000402061.3
ENST00000255784.5
coiled-coil domain containing 134
chr7_+_128784712 0.18 ENST00000289407.4
tetraspanin 33
chr8_+_22102626 0.18 ENST00000519237.1
ENST00000397802.4
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr19_-_40931891 0.17 ENST00000357949.4
SERTA domain containing 1
chr1_-_2145620 0.17 ENST00000545087.1
Uncharacterized protein
chr2_+_201676256 0.17 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
basic leucine zipper and W2 domains 1
chr20_-_896960 0.17 ENST00000381922.3
ENST00000546022.1
angiopoietin 4
chrX_-_153775426 0.17 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr5_+_135468516 0.16 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD family member 5
chr13_-_50367057 0.16 ENST00000261667.3
karyopherin alpha 3 (importin alpha 4)
chr14_-_77279153 0.16 ENST00000251089.2
angel homolog 1 (Drosophila)
chr17_-_40306934 0.16 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
Uncharacterized protein
RAB5C, member RAS oncogene family
chrX_+_73641286 0.16 ENST00000587091.1
solute carrier family 16, member 2 (thyroid hormone transporter)
chr13_+_98086445 0.16 ENST00000245304.4
RAP2A, member of RAS oncogene family
chr19_+_55851221 0.16 ENST00000255613.3
ENST00000539076.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr8_-_37756972 0.16 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11 family interacting protein 1 (class I)
chr1_+_214161272 0.15 ENST00000498508.2
ENST00000366958.4
prospero homeobox 1
chr1_-_19283163 0.15 ENST00000455833.2
intermediate filament family orphan 2
chr10_+_111967345 0.15 ENST00000332674.5
ENST00000453116.1
MAX interactor 1, dimerization protein
chr19_-_11450249 0.15 ENST00000222120.3
RAB3D, member RAS oncogene family
chr14_+_24583836 0.15 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr16_-_4987065 0.15 ENST00000590782.2
ENST00000345988.2
periplakin
chr11_+_76494253 0.15 ENST00000333090.4
tsukushi, small leucine rich proteoglycan
chr11_-_61684962 0.14 ENST00000394836.2
RAB3A interacting protein (rabin3)-like 1
chrX_-_57937067 0.14 ENST00000358697.4
zinc finger, X-linked, duplicated A
chr2_+_42275153 0.14 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chrX_-_119077695 0.14 ENST00000371410.3
NFKB activating protein
chr15_-_34628951 0.14 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_-_50222187 0.14 ENST00000335999.6
NCK-associated protein 5-like

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCUCAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 0.8 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.3 0.8 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 0.7 GO:0003192 mitral valve formation(GO:0003192)
0.2 0.9 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 0.5 GO:2000309 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.2 0.5 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.4 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.4 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.8 GO:0097102 endothelial tip cell fate specification(GO:0097102)
0.1 1.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.6 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.6 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 0.5 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.8 GO:1990834 response to odorant(GO:1990834)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.4 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.3 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.4 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.6 GO:0006477 protein sulfation(GO:0006477)
0.0 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.3 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.2 GO:0097527 retinal cell programmed cell death(GO:0046666) endosomal lumen acidification(GO:0048388) necroptotic signaling pathway(GO:0097527)
0.0 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.4 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.5 GO:0048535 lymph node development(GO:0048535)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0051604 protein maturation(GO:0051604)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.9 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.8 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043260 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.1 0.4 GO:0044393 microspike(GO:0044393)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 0.5 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.5 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation