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Illumina Body Map 2: averaged replicates

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Results for GLIS1

Z-value: 0.28

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Transcription factors associated with GLIS1

Gene Symbol Gene ID Gene Info
GLIS1
ENSG00000174332.3 GLIS family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS1hg19_v2_chr1_-_54199877_541998770.125.2e-01Click!

Activity profile of GLIS1 motif

Sorted Z-values of GLIS1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_68671310 0.38 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr18_+_11752040 0.32 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_59250815 0.30 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr19_-_38397228 0.30 ENST00000447313.2
WDR87
WD repeat domain 87
chr18_+_11751493 0.25 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr18_+_11751466 0.25 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr15_-_43882140 0.23 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr17_-_79917645 0.21 ENST00000477214.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr17_+_80332153 0.17 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr19_+_40697514 0.13 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr11_-_68671264 0.11 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr16_+_58059470 0.10 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr19_+_1495362 0.06 ENST00000395479.4
REEP6
receptor accessory protein 6
chr4_+_190992087 0.05 ENST00000553598.1
DUX4L7
double homeobox 4 like 7
chr11_-_299519 0.03 ENST00000382614.2
IFITM5
interferon induced transmembrane protein 5
chr19_-_49828438 0.02 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
SLC6A16
solute carrier family 6, member 16
chr4_+_191001979 0.00 ENST00000538692.1
DUX4L4
double homeobox 4 like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway