Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for GMEB2
Z-value: 2.10
Motif logo
Transcription factors associated with GMEB2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB2 | hg19_v2_chr20_-_62258394_62258464 | -0.27 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_65346555 Show fit | 2.11 |
ENST00000542895.1
ENST00000556626.1 |
spectrin, beta, erythrocytic |
|
| chr7_-_19748640 Show fit | 1.82 |
ENST00000222567.5
|
TWIST neighbor |
|
| chr17_-_73975198 Show fit | 1.66 |
ENST00000301608.4
ENST00000588176.1 |
acyl-CoA oxidase 1, palmitoyl |
|
| chr19_+_4791722 Show fit | 1.66 |
ENST00000269856.3
|
fem-1 homolog a (C. elegans) |
|
| chr1_+_207226574 Show fit | 1.60 |
ENST00000367080.3
ENST00000367079.2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
|
| chr3_+_50654550 Show fit | 1.42 |
ENST00000430409.1
ENST00000357955.2 |
mitogen-activated protein kinase-activated protein kinase 3 |
|
| chr17_+_66511540 Show fit | 1.37 |
ENST00000588188.2
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
|
| chr3_+_50654821 Show fit | 1.35 |
ENST00000457064.1
|
mitogen-activated protein kinase-activated protein kinase 3 |
|
| chr8_-_42396185 Show fit | 1.33 |
ENST00000518717.1
|
solute carrier family 20 (phosphate transporter), member 2 |
|
| chr3_+_57261859 Show fit | 1.33 |
ENST00000495803.1
ENST00000444459.1 |
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GMEB2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.2 | 4.4 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 4.1 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.0 | 3.3 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.0 | 3.1 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.2 | 2.8 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.1 | 2.8 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 2.7 | GO:0033108 | mitochondrial respiratory chain complex assembly(GO:0033108) |
| 0.1 | 2.6 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 2.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 9.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 6.4 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 4.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.2 | 4.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 3.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 3.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 3.5 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 3.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 3.2 | GO:0005730 | nucleolus(GO:0005730) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.3 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 3.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 3.0 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.2 | 2.9 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.1 | 2.9 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.6 | 2.8 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.0 | 2.8 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 2.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 2.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.3 | 2.4 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 2.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 2.2 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 2.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.5 | REACTOME TRNA AMINOACYLATION | Genes involved in tRNA Aminoacylation |
| 0.1 | 5.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 4.2 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 4.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 4.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 3.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 3.0 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 2.9 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.1 | 2.8 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 2.8 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |