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Illumina Body Map 2: averaged replicates

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Results for GUAACAG

Z-value: 0.70

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miRNA associated with seed GUAACAG

NamemiRBASE accession
hsa-miR-194-5p
MIMAT0000460

Activity profile of GUAACAG motif

Sorted Z-values of GUAACAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_96873921 1.59 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chrX_+_70435044 1.49 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1
gap junction protein, beta 1, 32kDa
chr11_+_12695944 1.29 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_+_55370487 1.25 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chr11_+_101981169 1.19 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr20_-_43977055 1.12 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr13_-_107187462 1.07 ENST00000245323.4
EFNB2
ephrin-B2
chr8_+_102504651 1.05 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr6_+_19837592 1.05 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr16_-_51185149 1.04 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr3_+_37493610 0.95 ENST00000264741.5
ITGA9
integrin, alpha 9
chr3_+_39851094 0.94 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr14_+_85996471 0.93 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr14_-_38064198 0.90 ENST00000250448.2
FOXA1
forkhead box A1
chr18_+_55102917 0.89 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr2_-_208634287 0.87 ENST00000295417.3
FZD5
frizzled family receptor 5
chr12_-_88974236 0.86 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr16_+_86544113 0.84 ENST00000262426.4
FOXF1
forkhead box F1
chr10_-_33623564 0.81 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr1_-_220101944 0.73 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chrX_-_33146477 0.69 ENST00000378677.2
DMD
dystrophin
chr1_+_82266053 0.65 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr5_-_115910630 0.63 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_225840747 0.61 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr11_-_86666427 0.61 ENST00000531380.1
FZD4
frizzled family receptor 4
chr12_+_72666407 0.60 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr7_-_155604967 0.59 ENST00000297261.2
SHH
sonic hedgehog
chr15_+_62853562 0.59 ENST00000561311.1
TLN2
talin 2
chr14_-_35182994 0.57 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr4_+_145567173 0.55 ENST00000296575.3
HHIP
hedgehog interacting protein
chr4_-_23891693 0.52 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_+_107811162 0.52 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr12_+_124069070 0.48 ENST00000262225.3
ENST00000438031.2
TMED2
transmembrane emp24 domain trafficking protein 2
chr7_-_94285511 0.48 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr3_-_98620500 0.48 ENST00000326840.6
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr11_-_115375107 0.47 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr15_-_37390482 0.46 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr12_-_76425368 0.42 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chrX_+_152907913 0.42 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr1_-_156051789 0.42 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr9_-_91793675 0.41 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr4_+_128703295 0.37 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr8_+_77593448 0.37 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr5_+_177019159 0.35 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr16_-_58768177 0.35 ENST00000434819.2
ENST00000245206.5
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial
chr11_-_111175739 0.34 ENST00000532918.1
COLCA1
colorectal cancer associated 1
chr3_+_38495333 0.33 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr6_+_133562472 0.33 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4
eyes absent homolog 4 (Drosophila)
chr7_-_151217001 0.31 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr10_+_102505468 0.30 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr6_-_154831779 0.30 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr3_+_147127142 0.30 ENST00000282928.4
ZIC1
Zic family member 1
chr10_-_27703269 0.28 ENST00000438700.3
PTCHD3
patched domain containing 3
chr8_-_97173020 0.28 ENST00000287020.5
GDF6
growth differentiation factor 6
chr9_-_127533519 0.28 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr5_-_137090028 0.28 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr11_-_64901978 0.27 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr10_+_124895472 0.26 ENST00000357878.5
HMX3
H6 family homeobox 3
chrX_+_49687216 0.26 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr8_+_58907104 0.26 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr16_+_69599861 0.25 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr3_-_149688896 0.25 ENST00000239940.7
PFN2
profilin 2
chr17_-_57784755 0.24 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
PTRH2
peptidyl-tRNA hydrolase 2
chr4_+_166794383 0.23 ENST00000061240.2
ENST00000507499.1
TLL1
tolloid-like 1
chr12_+_93965451 0.23 ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chr8_+_81397876 0.21 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr3_-_57583130 0.21 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr1_+_27248203 0.21 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr7_-_98741642 0.21 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr11_+_74660278 0.21 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr5_-_41510656 0.21 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_-_100070363 0.20 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr2_-_213403565 0.19 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr2_-_190445499 0.19 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chrX_-_71933888 0.18 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)
chr17_+_35294075 0.18 ENST00000254457.5
LHX1
LIM homeobox 1
chr14_+_55034599 0.17 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr19_-_40791302 0.16 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr11_+_61520075 0.16 ENST00000278836.5
MYRF
myelin regulatory factor
chr1_-_153958805 0.16 ENST00000368575.3
RAB13
RAB13, member RAS oncogene family
chr22_-_30642728 0.16 ENST00000403987.3
LIF
leukemia inhibitory factor
chr20_-_60640866 0.15 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr16_-_73082274 0.14 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr4_+_87856129 0.14 ENST00000395146.4
ENST00000507468.1
AFF1
AF4/FMR2 family, member 1
chr9_+_4679555 0.14 ENST00000381858.1
ENST00000381854.3
CDC37L1
cell division cycle 37-like 1
chr10_-_72648541 0.14 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr21_-_16437255 0.14 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr9_-_74980113 0.14 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr1_+_52682052 0.13 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr3_-_122233723 0.13 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr20_-_50419055 0.13 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr16_+_22825475 0.13 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_2151523 0.13 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr5_-_83680603 0.12 ENST00000296591.5
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr1_-_205719295 0.12 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_174830430 0.12 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr16_-_31100284 0.11 ENST00000280606.6
PRSS53
protease, serine, 53
chr12_+_93771659 0.11 ENST00000337179.5
ENST00000415493.2
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr2_-_11484710 0.10 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr7_-_27219632 0.10 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr15_+_64443905 0.10 ENST00000325881.4
SNX22
sorting nexin 22
chr10_+_114709999 0.10 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_232329186 0.10 ENST00000322723.4
NCL
nucleolin
chr10_-_13390270 0.09 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr9_-_124989804 0.09 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr1_-_52456352 0.08 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr5_-_59189545 0.08 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_135333722 0.08 ENST00000316077.9
MAP7D3
MAP7 domain containing 3
chr14_-_93799360 0.08 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7
BTB (POZ) domain containing 7
chr13_-_44361025 0.08 ENST00000261488.6
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr2_-_176948641 0.08 ENST00000308618.4
EVX2
even-skipped homeobox 2
chr8_+_125551338 0.08 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NDUFB9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr1_+_63788730 0.08 ENST00000371116.2
FOXD3
forkhead box D3
chr22_+_40390930 0.08 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr5_-_139726181 0.08 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr7_-_558876 0.07 ENST00000354513.5
ENST00000402802.3
PDGFA
platelet-derived growth factor alpha polypeptide
chr2_-_122407097 0.07 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr4_+_52709229 0.07 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chr1_+_184356188 0.07 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr16_-_12009735 0.07 ENST00000439887.2
ENST00000434724.2
GSPT1
G1 to S phase transition 1
chr3_+_69812877 0.06 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr21_-_34960948 0.06 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
DONSON
downstream neighbor of SON
chr20_-_524455 0.06 ENST00000349736.5
ENST00000217244.3
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr12_-_29534074 0.06 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC2
ERGIC and golgi 2
chr1_-_93645818 0.06 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr3_+_9439400 0.05 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SETD5
SET domain containing 5
chr8_+_117963190 0.05 ENST00000427715.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr3_+_197476621 0.05 ENST00000241502.4
FYTTD1
forty-two-three domain containing 1
chr14_-_57735528 0.05 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr17_-_33416231 0.05 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr19_+_41882598 0.04 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
TMEM91
CTC-435M10.3
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr5_+_56469775 0.04 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr2_+_210444142 0.04 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr14_+_39736299 0.04 ENST00000341502.5
ENST00000396158.2
ENST00000280083.3
CTAGE5
CTAGE family, member 5
chr18_+_9913977 0.04 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr7_-_152133059 0.03 ENST00000262189.6
ENST00000355193.2
KMT2C
lysine (K)-specific methyltransferase 2C
chr8_+_42752053 0.03 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr1_-_211752073 0.03 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr14_-_91282726 0.03 ENST00000328459.6
ENST00000357056.2
TTC7B
tetratricopeptide repeat domain 7B
chr9_+_108006880 0.03 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
SLC44A1
solute carrier family 44 (choline transporter), member 1
chr17_-_80231557 0.03 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr12_-_6716534 0.02 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4
chromodomain helicase DNA binding protein 4
chr17_+_40985407 0.02 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr18_-_23670546 0.02 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr7_+_119913688 0.02 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr20_+_36661910 0.02 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr16_+_53088885 0.02 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr3_+_37903432 0.02 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_2985760 0.02 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr12_-_31744031 0.01 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr22_+_41347363 0.01 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr12_+_123868320 0.01 ENST00000402868.3
ENST00000330479.4
SETD8
SET domain containing (lysine methyltransferase) 8
chr3_-_114790179 0.01 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_102962929 0.01 ENST00000260247.5
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr19_-_14606900 0.00 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr3_+_14166440 0.00 ENST00000306077.4
TMEM43
transmembrane protein 43
chr1_+_52521928 0.00 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr10_+_116581503 0.00 ENST00000369248.4
ENST00000369250.3
ENST00000369246.1
FAM160B1
family with sequence similarity 160, member B1
chr1_-_11120057 0.00 ENST00000376957.2
SRM
spermidine synthase
chr15_-_72410109 0.00 ENST00000564571.1
MYO9A
myosin IXA

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAACAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 GO:0060458 right lung development(GO:0060458)
0.5 1.5 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.4 1.3 GO:0061010 endodermal cell fate determination(GO:0007493) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.3 0.9 GO:0060061 Spemann organizer formation(GO:0060061)
0.3 0.9 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3 1.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 1.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.8 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 1.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.8 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 1.2 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1 0.4 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0035566 regulation of metanephros size(GO:0035566)
0.1 1.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.2 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.1 0.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.2 GO:0021551 central nervous system morphogenesis(GO:0021551) cardiac muscle tissue regeneration(GO:0061026)
0.1 0.2 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.4 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 1.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.6 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.1 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0060136 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 1.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 0.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 1.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 2.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network