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Illumina Body Map 2: averaged replicates

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Results for HIF1A

Z-value: 0.86

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
HIF1A
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62162258_62162269-0.402.3e-02Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_220101944 1.86 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr11_-_35440579 1.49 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_-_35440796 1.45 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_11034403 1.41 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr7_+_100318423 1.32 ENST00000252723.2
EPO
erythropoietin
chr7_+_26331541 1.26 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr12_+_6977323 1.17 ENST00000462761.1
TPI1
triosephosphate isomerase 1
chr11_+_75479763 1.11 ENST00000228027.7
DGAT2
diacylglycerol O-acyltransferase 2
chr7_+_26331678 1.10 ENST00000446848.2
SNX10
sorting nexin 10
chr11_+_75479850 1.09 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr12_+_6977258 1.00 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
TPI1
triosephosphate isomerase 1
chr11_-_118901559 0.93 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr9_+_4490394 0.91 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr16_-_81129845 0.90 ENST00000569885.1
ENST00000566566.1
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr5_+_70883117 0.88 ENST00000340941.6
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr5_+_70883178 0.88 ENST00000323375.8
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr5_+_70883154 0.86 ENST00000509358.2
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr3_+_25831567 0.81 ENST00000280701.3
ENST00000420173.2
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr2_-_216946500 0.81 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr7_+_65540853 0.75 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr10_+_75910960 0.75 ENST00000539909.1
ENST00000286621.2
ADK
adenosine kinase
chr7_-_95951310 0.74 ENST00000542654.1
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr7_+_65540780 0.74 ENST00000304874.9
ASL
argininosuccinate lyase
chrX_+_77359726 0.74 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chrX_+_77359671 0.74 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr7_-_95951334 0.73 ENST00000265631.5
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr5_+_174905532 0.72 ENST00000502393.1
ENST00000506963.1
SFXN1
sideroflexin 1
chr14_+_92789498 0.71 ENST00000531433.1
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_95951432 0.71 ENST00000416240.2
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr2_+_173420697 0.70 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr1_+_65613852 0.69 ENST00000327299.7
AK4
adenylate kinase 4
chr12_-_49318715 0.68 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr9_+_115983808 0.68 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1
chr15_-_60884706 0.67 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr16_-_81129951 0.65 ENST00000315467.3
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chrX_+_105969893 0.64 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr11_+_14665263 0.62 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr15_+_41056255 0.61 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr4_-_39529049 0.61 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH
UDP-glucose 6-dehydrogenase
chr11_-_47664072 0.61 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
MTCH2
mitochondrial carrier 2
chr15_+_41056218 0.60 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr11_+_14665373 0.60 ENST00000455098.2
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr14_+_64970662 0.60 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chr8_+_95908041 0.59 ENST00000396113.1
ENST00000519136.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_-_18343669 0.59 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr12_+_56862301 0.59 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr7_+_96747030 0.59 ENST00000360382.4
ACN9
ACN9 homolog (S. cerevisiae)
chr6_+_108487245 0.58 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr14_+_64970427 0.57 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_+_230203010 0.56 ENST00000541865.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr1_-_231376836 0.55 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr20_+_44657845 0.55 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr8_+_97274119 0.54 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr5_+_49962495 0.53 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_-_8939265 0.53 ENST00000489867.1
ENO1
enolase 1, (alpha)
chr2_-_119916459 0.52 ENST00000272520.3
C1QL2
complement component 1, q subcomponent-like 2
chr5_+_159343688 0.51 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr13_-_52027134 0.50 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr6_-_33679452 0.48 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr9_-_139922726 0.48 ENST00000265662.5
ENST00000371605.3
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_231376867 0.48 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
C1orf131
chromosome 1 open reading frame 131
chr1_-_6269448 0.48 ENST00000465335.1
RPL22
ribosomal protein L22
chr9_-_123476612 0.47 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr20_+_44657807 0.47 ENST00000372315.1
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr11_-_74204742 0.46 ENST00000310109.4
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr4_-_39529180 0.46 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH
UDP-glucose 6-dehydrogenase
chr14_-_53162361 0.46 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr8_+_95907993 0.45 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr14_-_64970494 0.45 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr12_-_121734489 0.45 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_-_52719546 0.45 ENST00000439181.1
ENST00000449505.1
PBRM1
polybromo 1
chr17_-_67323232 0.44 ENST00000592568.1
ENST00000392676.3
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr1_+_230202936 0.44 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr22_+_19702069 0.44 ENST00000412544.1
SEPT5
septin 5
chr20_+_56964253 0.43 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr2_-_220118631 0.43 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr1_+_214454492 0.43 ENST00000366957.5
ENST00000415093.2
SMYD2
SET and MYND domain containing 2
chr9_+_133569108 0.43 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2
exosome component 2
chr9_-_139922631 0.42 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_136857403 0.42 ENST00000406606.3
ENST00000371850.3
VAV2
vav 2 guanine nucleotide exchange factor
chr1_+_74663994 0.42 ENST00000472069.1
FPGT
fucose-1-phosphate guanylyltransferase
chr12_-_64616019 0.42 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr1_+_100436065 0.42 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr17_-_67323305 0.42 ENST00000392677.2
ENST00000593153.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr9_-_123476719 0.41 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr20_+_33464407 0.41 ENST00000253382.5
ACSS2
acyl-CoA synthetase short-chain family member 2
chr11_-_18343725 0.41 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr20_+_33464238 0.40 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr3_-_58419537 0.40 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr1_+_74663896 0.40 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chrX_+_24483338 0.40 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr11_+_12132117 0.40 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr17_+_34890807 0.40 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr19_-_5720123 0.40 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1
lon peptidase 1, mitochondrial
chr16_+_447226 0.40 ENST00000433358.1
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr11_+_18720316 0.39 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr11_-_57283159 0.39 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr15_+_52311398 0.39 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr11_-_73471655 0.39 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr6_+_64282447 0.39 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_228353495 0.38 ENST00000366711.3
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr17_+_27052892 0.38 ENST00000579671.1
ENST00000579060.1
NEK8
NIMA-related kinase 8
chr12_+_46777450 0.38 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr17_-_17942473 0.37 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
chr16_+_447209 0.37 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr8_-_97273807 0.37 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chr2_-_220083076 0.37 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr12_+_6643676 0.37 ENST00000396856.1
ENST00000396861.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr2_-_73460334 0.37 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr9_-_115983568 0.36 ENST00000446284.1
ENST00000414250.1
FKBP15
FK506 binding protein 15, 133kDa
chr10_+_101419187 0.36 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr2_+_170683979 0.36 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr3_+_39851170 0.36 ENST00000425621.1
ENST00000396217.3
MYRIP
myosin VIIA and Rab interacting protein
chr6_+_64281906 0.36 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr14_-_54908043 0.35 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr8_+_98656336 0.35 ENST00000336273.3
MTDH
metadherin
chrX_-_84363974 0.35 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr17_-_2615031 0.35 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr11_+_126225789 0.35 ENST00000530591.1
ENST00000534083.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr3_-_183543301 0.35 ENST00000318631.3
ENST00000431348.1
MAP6D1
MAP6 domain containing 1
chr1_-_113498943 0.35 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr20_+_33464368 0.34 ENST00000484354.1
ENST00000493805.2
ENST00000473172.1
ACSS2
acyl-CoA synthetase short-chain family member 2
chr1_-_166136187 0.34 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr8_-_102218292 0.34 ENST00000518336.1
ENST00000520454.1
ZNF706
zinc finger protein 706
chr3_-_127541679 0.34 ENST00000265052.5
MGLL
monoglyceride lipase
chr3_-_167813672 0.34 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr11_-_14665163 0.33 ENST00000418988.2
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr1_+_171750776 0.33 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr1_-_113498616 0.33 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr19_-_5719860 0.33 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr8_-_9760839 0.33 ENST00000519461.1
ENST00000517675.1
LINC00599
long intergenic non-protein coding RNA 599
chr8_+_98656693 0.33 ENST00000519934.1
MTDH
metadherin
chr17_-_36831156 0.33 ENST00000325814.5
C17orf96
chromosome 17 open reading frame 96
chr18_+_43913919 0.33 ENST00000587853.1
RNF165
ring finger protein 165
chr11_+_126225529 0.33 ENST00000227495.6
ENST00000444328.2
ENST00000356132.4
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr20_+_36661910 0.32 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr4_+_83351715 0.32 ENST00000273920.3
ENOPH1
enolase-phosphatase 1
chr2_+_68384976 0.32 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr4_-_25162188 0.32 ENST00000302922.3
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr3_+_19988566 0.32 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr7_-_127032114 0.32 ENST00000436992.1
ZNF800
zinc finger protein 800
chr1_-_8938736 0.31 ENST00000234590.4
ENO1
enolase 1, (alpha)
chr1_+_39571026 0.31 ENST00000524432.1
MACF1
microtubule-actin crosslinking factor 1
chr3_+_19988885 0.31 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr2_+_170683942 0.31 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr15_-_43622736 0.31 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr13_+_103451548 0.31 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr6_+_89791507 0.31 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr16_+_53164956 0.31 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr16_-_30022293 0.30 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr19_+_41903709 0.30 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr8_+_125551338 0.30 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NDUFB9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr19_-_5720248 0.30 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr1_-_167522982 0.29 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr7_-_92465868 0.29 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chrX_-_47509994 0.29 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr17_-_2614927 0.29 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr20_-_3065362 0.29 ENST00000380293.3
AVP
arginine vasopressin
chr15_+_43622843 0.29 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
ADAL
adenosine deaminase-like
chr14_-_53162215 0.28 ENST00000554251.1
ERO1L
ERO1-like (S. cerevisiae)
chrX_-_69509738 0.28 ENST00000374454.1
ENST00000239666.4
PDZD11
PDZ domain containing 11
chr3_+_19988736 0.28 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr11_-_65548265 0.28 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr16_+_29466426 0.28 ENST00000567248.1
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr16_-_23568651 0.28 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
EARS2
glutamyl-tRNA synthetase 2, mitochondrial
chr17_+_40719073 0.28 ENST00000435881.2
ENST00000246912.4
ENST00000346833.4
ENST00000591024.1
MLX
MLX, MAX dimerization protein
chr1_-_166135952 0.27 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr14_+_77787227 0.27 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr8_+_55047763 0.27 ENST00000260102.4
ENST00000519831.1
MRPL15
mitochondrial ribosomal protein L15
chr1_-_1709845 0.27 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr1_-_1710229 0.26 ENST00000341991.3
NADK
NAD kinase
chr7_+_43152191 0.26 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr10_-_101945771 0.26 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr19_-_663147 0.26 ENST00000606702.1
RNF126
ring finger protein 126
chr3_+_52719936 0.26 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_+_216946589 0.26 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr19_-_663171 0.26 ENST00000606896.1
ENST00000589762.2
RNF126
ring finger protein 126
chr17_-_5342380 0.25 ENST00000225698.4
C1QBP
complement component 1, q subcomponent binding protein
chr1_-_166944652 0.25 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
ILDR2
immunoglobulin-like domain containing receptor 2
chr11_-_62414070 0.25 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr4_+_25162253 0.25 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr2_-_220083692 0.24 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr20_+_56964169 0.24 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr17_-_34890759 0.23 ENST00000431794.3
MYO19
myosin XIX
chr2_-_28113217 0.23 ENST00000444339.2
RBKS
ribokinase
chr13_+_27998681 0.23 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr16_-_4466565 0.23 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr20_+_42086525 0.23 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr16_+_24621546 0.23 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr11_+_73498973 0.23 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr16_-_4897266 0.22 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr3_-_71834207 0.22 ENST00000295619.3
PROK2
prokineticin 2
chr18_+_43913973 0.22 ENST00000590330.1
RNF165
ring finger protein 165
chr14_-_88459182 0.22 ENST00000544807.2
GALC
galactosylceramidase
chr6_-_153304148 0.22 ENST00000229758.3
FBXO5
F-box protein 5
chr8_+_67341239 0.22 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr11_-_6624801 0.22 ENST00000534343.1
ENST00000254605.6
RRP8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr3_+_49507559 0.22 ENST00000421560.1
ENST00000308775.2
ENST00000545947.1
ENST00000541308.1
ENST00000539901.1
ENST00000538711.1
ENST00000418588.1
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr1_-_43833628 0.22 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr3_-_156272924 0.22 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 2.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.4 1.3 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.4 2.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.4 1.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.4 3.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.3 1.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.3 1.0 GO:0040040 thermosensory behavior(GO:0040040)
0.3 1.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 1.2 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.3 2.6 GO:0006552 leucine catabolic process(GO:0006552)
0.2 0.7 GO:0044209 AMP salvage(GO:0044209)
0.2 0.7 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.2 0.7 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 2.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.2 2.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.2 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 1.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.1 0.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 1.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 1.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.3 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.6 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.5 GO:0031639 plasminogen activation(GO:0031639)
0.1 2.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.7 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.8 GO:0015886 heme transport(GO:0015886)
0.0 0.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.8 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.9 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0072599 SRP-dependent cotranslational protein targeting to membrane(GO:0006614) protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.5 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.7 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 1.5 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.4 2.6 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 2.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 1.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.0 1.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.5 1.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.4 1.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 2.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.4 2.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.4 1.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.4 1.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.4 1.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.4 3.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.0 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 0.8 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.3 0.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 0.8 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.7 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.2 1.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 2.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.9 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.6 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.3 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.7 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.3 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0030984 kininogen binding(GO:0030984)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 7.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 4.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 2.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription