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Illumina Body Map 2: averaged replicates

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Results for HMGA2

Z-value: 1.37

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Transcription factors associated with HMGA2

Gene Symbol Gene ID Gene Info
HMGA2
ENSG00000149948.9 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA2hg19_v2_chr12_+_66218903_66218913-0.309.6e-02Click!

Activity profile of HMGA2 motif

Sorted Z-values of HMGA2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_36297632 4.39 ENST00000588266.2
PRODH2
proline dehydrogenase (oxidase) 2
chr8_-_105479270 3.91 ENST00000521573.2
ENST00000351513.2
DPYS
dihydropyrimidinase
chr12_+_18414446 3.78 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr15_+_58702742 3.68 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr6_-_107230334 3.26 ENST00000607090.1
RP1-60O19.1
RP1-60O19.1
chr10_-_129691195 3.18 ENST00000368671.3
CLRN3
clarin 3
chr1_+_196621002 3.16 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr10_-_5046042 3.08 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr14_-_65409502 2.94 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_65409438 2.83 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_94759361 2.54 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759408 2.49 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759595 2.41 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_196621156 2.27 ENST00000359637.2
CFH
complement factor H
chr20_+_38633006 2.24 ENST00000432633.1
ENST00000445606.1
RP11-101E14.2
RP11-101E14.2
chrX_+_2670066 2.19 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr5_-_135290651 2.03 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr12_-_21757774 1.98 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr11_+_69455855 1.95 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr12_+_21207503 1.89 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_-_216257849 1.88 ENST00000456923.1
FN1
fibronectin 1
chr2_+_120436760 1.71 ENST00000445518.1
ENST00000409951.1
TMEM177
transmembrane protein 177
chr2_-_151395525 1.71 ENST00000439275.1
RND3
Rho family GTPase 3
chr14_+_37641012 1.71 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr2_+_120436733 1.68 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
TMEM177
transmembrane protein 177
chr6_+_31887761 1.54 ENST00000413154.1
C2
complement component 2
chr3_+_193853927 1.38 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr6_-_52705641 1.28 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr5_-_135290705 1.26 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_235887329 1.26 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3BP4
SH3-domain binding protein 4
chrX_+_135614293 1.24 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr2_+_1417228 1.23 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr2_-_180610767 1.18 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr4_-_34271356 1.07 ENST00000514877.1
RP11-548L20.1
RP11-548L20.1
chr2_+_108863651 1.07 ENST00000329106.2
ENST00000376700.1
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr15_+_43885252 0.99 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr6_+_123110302 0.97 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr9_+_42704004 0.91 ENST00000457288.1
CBWD7
COBW domain containing 7
chr1_+_55464600 0.87 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr19_-_11456905 0.86 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr15_+_43985084 0.86 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_11457162 0.84 ENST00000590482.1
TMEM205
transmembrane protein 205
chrX_-_7895755 0.81 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr2_-_183387064 0.80 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_-_7895479 0.80 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4
chr15_+_84904525 0.77 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr19_-_11456872 0.77 ENST00000586218.1
TMEM205
transmembrane protein 205
chr2_-_183387283 0.77 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387430 0.77 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_+_184826418 0.76 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr6_-_127664736 0.72 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
ECHDC1
enoyl CoA hydratase domain containing 1
chr19_-_11457082 0.71 ENST00000587948.1
TMEM205
transmembrane protein 205
chrX_-_77150911 0.71 ENST00000373336.3
MAGT1
magnesium transporter 1
chrX_-_77150985 0.68 ENST00000358075.6
MAGT1
magnesium transporter 1
chr12_+_59194154 0.66 ENST00000548969.1
RP11-362K2.2
Protein LOC100506869
chr19_-_11456935 0.64 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr8_-_86162077 0.64 ENST00000551479.1
RP11-219B4.6
Uncharacterized protein
chr6_-_127664683 0.62 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr17_-_30186328 0.60 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chr2_-_114461655 0.59 ENST00000424612.1
AC017074.2
AC017074.2
chr1_-_43638168 0.59 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr19_-_11456722 0.59 ENST00000354882.5
TMEM205
transmembrane protein 205
chr15_-_70994612 0.58 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr19_-_12267524 0.57 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr9_+_108463234 0.57 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr3_+_154801312 0.55 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr14_+_50291993 0.55 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr8_+_9911778 0.50 ENST00000317173.4
ENST00000441698.2
MSRA
methionine sulfoxide reductase A
chr18_+_11851383 0.47 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr2_-_287320 0.46 ENST00000401503.1
FAM150B
family with sequence similarity 150, member B
chr10_-_101673782 0.45 ENST00000422692.1
DNMBP
dynamin binding protein
chr6_+_88106840 0.42 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr15_+_86686953 0.40 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr6_-_132967142 0.36 ENST00000275216.1
TAAR1
trace amine associated receptor 1
chrX_+_2670153 0.35 ENST00000509484.2
XG
Xg blood group
chrX_-_23926004 0.35 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr5_+_150827143 0.34 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr15_-_83018198 0.33 ENST00000557886.1
RP13-996F3.4
golgin A6 family-like 19
chr2_+_177134134 0.32 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
MTX2
metaxin 2
chr2_+_177134201 0.32 ENST00000452865.1
MTX2
metaxin 2
chr3_+_106959530 0.31 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
LINC00883
long intergenic non-protein coding RNA 883
chr15_+_83098710 0.30 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr15_-_74659978 0.30 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr13_+_50656307 0.30 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr1_+_104104379 0.27 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chrX_-_71792477 0.27 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
HDAC8
histone deacetylase 8
chr1_-_226374373 0.26 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr18_-_21017817 0.26 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241
transmembrane protein 241
chr6_+_111580508 0.25 ENST00000368847.4
KIAA1919
KIAA1919
chr2_+_220144052 0.23 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_+_73230799 0.23 ENST00000579838.1
NUP85
nucleoporin 85kDa
chr15_+_82722225 0.22 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr11_+_73661364 0.21 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr2_-_287299 0.20 ENST00000405290.1
FAM150B
family with sequence similarity 150, member B
chr15_+_88120158 0.20 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr12_+_69979113 0.20 ENST00000299300.6
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr20_+_54967663 0.19 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chrX_-_135962923 0.16 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr11_-_130786400 0.15 ENST00000265909.4
SNX19
sorting nexin 19
chr2_+_220143989 0.15 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr12_+_69979210 0.15 ENST00000544368.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr12_+_65996599 0.15 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr17_-_26220366 0.14 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr3_-_157221128 0.12 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr15_+_30375158 0.12 ENST00000341650.6
ENST00000567927.1
GOLGA8J
golgin A8 family, member J
chr2_+_170683979 0.11 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr15_-_82939157 0.11 ENST00000559949.1
RP13-996F3.5
golgin A6 family-like 18
chr9_-_86955598 0.11 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr1_+_197886461 0.10 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chr11_-_130786333 0.10 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr12_+_113587558 0.08 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr2_+_170683942 0.08 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr1_+_144989309 0.08 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr10_-_36813162 0.07 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr1_+_227751231 0.07 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr1_+_28836561 0.07 ENST00000419074.1
RCC1
regulator of chromosome condensation 1
chr2_-_130031335 0.07 ENST00000375987.3
AC079586.1
AC079586.1
chr20_-_31989307 0.07 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
CDK5RAP1
CDK5 regulatory subunit associated protein 1
chr3_+_106959552 0.06 ENST00000473550.1
LINC00883
long intergenic non-protein coding RNA 883
chr10_+_35456444 0.06 ENST00000361599.4
CREM
cAMP responsive element modulator
chrX_-_134186144 0.05 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chrX_-_135962876 0.05 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr9_+_2157655 0.04 ENST00000452193.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_104296122 0.04 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr6_-_160209471 0.04 ENST00000539948.1
TCP1
t-complex 1
chr10_-_62332357 0.03 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_+_36608422 0.03 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_130300585 0.03 ENST00000511332.1
COL6A6
collagen, type VI, alpha 6
chr12_+_8309630 0.01 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr20_+_9966728 0.01 ENST00000449270.1
RP5-839B4.8
RP5-839B4.8

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0008218 bioluminescence(GO:0008218)
1.0 3.9 GO:0019482 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.6 1.9 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.6 4.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 1.4 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.4 3.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 0.8 GO:0001893 maternal placenta development(GO:0001893)
0.2 5.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 3.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.5 GO:0070141 response to UV-A(GO:0070141)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 2.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 3.8 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.3 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.9 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 1.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.3 GO:0043090 amino acid import(GO:0043090)
0.0 0.5 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 4.2 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 2.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 4.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 5.4 GO:0072562 blood microparticle(GO:0072562)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 7.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.8 3.9 GO:0002054 nucleobase binding(GO:0002054) dihydropyrimidinase activity(GO:0004157)
0.4 3.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.3 3.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.3 2.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 1.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 5.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 5.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 3.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 7.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.8 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 7.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 3.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 2.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols