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Illumina Body Map 2: averaged replicates

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Results for HMX3

Z-value: 1.69

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Transcription factors associated with HMX3

Gene Symbol Gene ID Gene Info
ENSG00000188620.9 H6 family homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX3hg19_v2_chr10_+_124895472_1248955080.336.1e-02Click!

Activity profile of HMX3 motif

Sorted Z-values of HMX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_140227048 3.90 ENST00000532602.1
protocadherin alpha 9
chr1_+_87012753 3.42 ENST00000370563.3
chloride channel accessory 4
chr21_+_41239243 2.97 ENST00000328619.5
Purkinje cell protein 4
chr18_+_29171689 2.69 ENST00000237014.3
transthyretin
chr1_+_87012922 2.65 ENST00000263723.5
chloride channel accessory 4
chr4_-_69817481 2.56 ENST00000251566.4
UDP glucuronosyltransferase 2 family, polypeptide A3
chr3_-_165555200 2.53 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr5_+_175288631 2.50 ENST00000509837.1
complexin 2
chr8_-_86290333 2.37 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr11_-_128894053 2.30 ENST00000392657.3
Rho GTPase activating protein 32
chr5_+_17404147 2.29 ENST00000507730.1
RP11-321E2.3
chr9_+_103947311 2.28 ENST00000395056.2
Lipid phosphate phosphatase-related protein type 1
chr2_+_108994633 2.25 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr6_-_52628271 2.15 ENST00000493422.1
glutathione S-transferase alpha 2
chr8_-_112039621 2.11 ENST00000523557.1
RP11-946L20.2
chr2_-_224467093 2.09 ENST00000305409.2
secretogranin II
chr17_-_42992856 2.06 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr5_-_35938674 2.06 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr14_+_24540046 2.06 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chr8_+_91803695 2.02 ENST00000417640.2
N-terminal EF-hand calcium binding protein 1
chr5_-_142077569 1.98 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr17_-_38821373 1.98 ENST00000394052.3
keratin 222
chr2_+_200472779 1.91 ENST00000427045.1
ENST00000419243.1
AC093590.1
chr4_-_88450244 1.91 ENST00000503414.1
SPARC-like 1 (hevin)
chr4_-_185139062 1.91 ENST00000296741.2
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr2_+_102953608 1.90 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr2_+_173686303 1.87 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_122854612 1.85 ENST00000264811.5
transient receptor potential cation channel, subfamily C, member 3
chr4_-_88449771 1.82 ENST00000535835.1
SPARC-like 1 (hevin)
chr12_+_107078474 1.82 ENST00000552866.1
ENST00000229387.5
regulatory factor X, 4 (influences HLA class II expression)
chr8_+_35649365 1.80 ENST00000437887.1
Uncharacterized protein
chrX_+_38420623 1.78 ENST00000378482.2
tetraspanin 7
chr4_+_41258786 1.77 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_-_94129244 1.74 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr6_-_84419101 1.74 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr18_-_24765248 1.73 ENST00000580774.1
ENST00000284224.8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr13_-_47471155 1.68 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr7_-_107883678 1.65 ENST00000417701.1
neuronal cell adhesion molecule
chr4_-_88450372 1.65 ENST00000543631.1
SPARC-like 1 (hevin)
chr2_+_155555201 1.65 ENST00000544049.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr2_-_209054709 1.65 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
chromosome 2 open reading frame 80
chrX_-_15511438 1.65 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr2_+_27071045 1.63 ENST00000401478.1
dihydropyrimidinase-like 5
chr1_+_77333117 1.62 ENST00000477717.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr4_-_90759440 1.59 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_224467002 1.58 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr15_+_54305101 1.57 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr2_+_27071292 1.56 ENST00000431402.1
ENST00000434719.1
dihydropyrimidinase-like 5
chr19_-_3478477 1.55 ENST00000591708.1
chromosome 19 open reading frame 77
chr18_+_50278430 1.54 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
deleted in colorectal carcinoma
chr3_-_187009646 1.52 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr4_-_16675930 1.49 ENST00000503178.2
LIM domain binding 2
chr3_+_26735991 1.48 ENST00000456208.2
leucine rich repeat containing 3B
chr7_+_97361218 1.48 ENST00000319273.5
tachykinin, precursor 1
chrX_+_38420783 1.48 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr4_+_69962185 1.47 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr15_+_51669513 1.46 ENST00000558426.1
gliomedin
chr1_+_99127225 1.44 ENST00000370189.5
ENST00000529992.1
sorting nexin 7
chr15_+_69857515 1.43 ENST00000559477.1
RP11-279F6.1
chr1_+_197237352 1.42 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr5_+_17404114 1.42 ENST00000508677.1
RP11-321E2.3
chr9_+_27109392 1.39 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr4_-_168155169 1.37 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_+_27070964 1.37 ENST00000288699.6
dihydropyrimidinase-like 5
chr7_-_16921601 1.37 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
anterior gradient 3
chr6_-_52668605 1.36 ENST00000334575.5
glutathione S-transferase alpha 1
chr6_+_29624758 1.35 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
myelin oligodendrocyte glycoprotein
chr6_-_169654139 1.35 ENST00000366787.3
thrombospondin 2
chr3_+_121613265 1.35 ENST00000295605.2
solute carrier family 15 (oligopeptide transporter), member 2
chr3_-_107099454 1.35 ENST00000593837.1
ENST00000599431.1
RP11-446H18.5
chr2_+_234621551 1.33 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr19_-_47975417 1.33 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_151693984 1.33 ENST00000479191.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr8_+_101349823 1.33 ENST00000519566.1
KB-1991G8.1
chr14_+_32798547 1.32 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr16_-_20364030 1.32 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
uromodulin
chr4_-_10686475 1.31 ENST00000226951.6
cytokine-dependent hematopoietic cell linker
chr6_+_12290586 1.31 ENST00000379375.5
endothelin 1
chrX_-_43741594 1.30 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chrX_-_92928557 1.30 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr18_-_61311485 1.30 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr18_-_24722995 1.30 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr10_-_7513904 1.29 ENST00000420395.1
RP5-1031D4.2
chr10_-_61900762 1.29 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr15_+_73976545 1.27 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276 molecule
chr15_-_56757329 1.26 ENST00000260453.3
meiosis-specific nuclear structural 1
chr1_-_110933611 1.25 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr4_-_46126093 1.24 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr16_-_19897455 1.23 ENST00000568214.1
ENST00000569479.1
G protein-coupled receptor, family C, group 5, member B
chr1_+_201979645 1.22 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_-_46293378 1.22 ENST00000330430.6
regulator of calcineurin 2
chr6_+_73076432 1.22 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr7_+_29603394 1.22 ENST00000319694.2
proline rich 15
chr5_-_11588907 1.21 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr1_+_156308403 1.20 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSSK6 activating co-chaperone
chr18_+_43304137 1.19 ENST00000502059.2
ENST00000586951.1
ENST00000589322.2
ENST00000415427.3
ENST00000535474.1
ENST00000402943.2
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr4_+_69962212 1.19 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_75174180 1.19 ENST00000413830.1
epithelial mitogen
chr1_+_15250596 1.18 ENST00000361144.5
kazrin, periplakin interacting protein
chr8_-_13134045 1.18 ENST00000512044.2
deleted in liver cancer 1
chr10_-_124459284 1.18 ENST00000432000.1
ENST00000329446.4
chromosome 10 open reading frame 120
chr8_-_112039643 1.18 ENST00000524283.1
RP11-946L20.2
chr4_-_90756769 1.17 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr2_+_166095898 1.17 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr15_-_30261066 1.17 ENST00000558447.1
tight junction protein 1
chr14_-_37642016 1.17 ENST00000331299.5
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr9_+_6215799 1.16 ENST00000417746.2
ENST00000456383.2
interleukin 33
chr12_-_15374343 1.16 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr6_+_88757507 1.15 ENST00000237201.1
sperm acrosome associated 1
chr15_+_101417919 1.15 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chrX_+_17755696 1.14 ENST00000419185.1
sex comb on midleg-like 1 (Drosophila)
chr18_-_24443151 1.14 ENST00000440832.3
aquaporin 4
chr15_-_78913521 1.14 ENST00000326828.5
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr6_-_26027480 1.14 ENST00000377364.3
histone cluster 1, H4b
chr19_-_51192661 1.14 ENST00000391813.1
SH3 and multiple ankyrin repeat domains 1
chr4_-_177116772 1.14 ENST00000280191.2
spermatogenesis associated 4
chr1_-_72566613 1.13 ENST00000306821.3
neuronal growth regulator 1
chr19_+_54466179 1.13 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr19_-_41985048 1.12 ENST00000599801.1
ENST00000595063.1
ENST00000598215.1
AC011526.1
chr8_+_67405794 1.12 ENST00000522977.1
ENST00000480005.1
chromosome 8 open reading frame 46
chr6_+_25652432 1.12 ENST00000377961.2
secretagogin, EF-hand calcium binding protein
chr5_-_102898465 1.10 ENST00000507423.1
ENST00000230792.2
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr15_-_78913628 1.10 ENST00000348639.3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr10_+_18240814 1.10 ENST00000377374.4
solute carrier family 39 (zinc transporter), member 12
chr5_-_9630463 1.09 ENST00000382492.2
taste receptor, type 2, member 1
chr16_-_20364122 1.09 ENST00000396138.4
ENST00000577168.1
uromodulin
chr12_-_123450986 1.09 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_-_67266939 1.08 ENST00000304526.2
insulin-like 5
chr7_+_95401877 1.08 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr11_+_64685026 1.07 ENST00000526559.1
protein phosphatase 2, regulatory subunit B', beta
chr5_+_140588269 1.07 ENST00000541609.1
ENST00000239450.2
protocadherin beta 12
chr6_+_26204825 1.07 ENST00000360441.4
histone cluster 1, H4e
chr3_+_159557637 1.06 ENST00000445224.2
schwannomin interacting protein 1
chr3_-_98235962 1.06 ENST00000513873.1
claudin domain containing 1
chr1_-_111174054 1.05 ENST00000369770.3
potassium voltage-gated channel, shaker-related subfamily, member 2
chr3_+_75955817 1.05 ENST00000487694.3
ENST00000602589.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chrX_+_36053908 1.05 ENST00000378660.2
calponin homology domain containing 2
chr5_+_140220769 1.05 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr14_+_24540154 1.05 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
copine VI (neuronal)
chr22_-_30814469 1.05 ENST00000598426.1
KIAA1658
chr6_+_112408768 1.04 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr6_+_29624898 1.03 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
myelin oligodendrocyte glycoprotein
chr14_-_47812321 1.03 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_+_108994466 1.03 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr11_-_7698453 1.02 ENST00000524608.1
cytochrome b5 reductase 2
chr5_-_142065612 1.02 ENST00000360966.5
ENST00000411960.1
fibroblast growth factor 1 (acidic)
chr12_+_26164645 1.02 ENST00000542004.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr13_-_49987885 1.02 ENST00000409082.1
calcium binding protein 39-like
chr1_-_211307404 1.02 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr18_+_68002675 1.02 ENST00000584919.1
Uncharacterized protein
chr19_-_51531210 1.01 ENST00000391804.3
kallikrein-related peptidase 11
chr14_-_80697396 1.00 ENST00000557010.1
deiodinase, iodothyronine, type II
chr8_-_30706608 1.00 ENST00000256246.2
testis expressed 15
chr21_-_22175341 1.00 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
long intergenic non-protein coding RNA 320
chr17_-_55911970 0.99 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
chrX_+_71996972 0.99 ENST00000334036.5
DMRT-like family C1B
chr3_+_38537960 0.99 ENST00000453767.1
endo/exonuclease (5'-3'), endonuclease G-like
chr21_+_44073916 0.98 ENST00000349112.3
ENST00000398224.3
phosphodiesterase 9A
chr2_-_134326009 0.98 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr5_+_140201183 0.96 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
protocadherin alpha 5
chr11_+_62104897 0.96 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
asparaginase like 1
chr17_-_29624343 0.95 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr5_+_175490540 0.95 ENST00000515817.1
family with sequence similarity 153, member B
chr8_-_124749609 0.95 ENST00000262219.6
ENST00000419625.1
annexin A13
chr11_-_101000445 0.95 ENST00000534013.1
progesterone receptor
chr19_-_51531272 0.94 ENST00000319720.7
kallikrein-related peptidase 11
chr15_+_35838396 0.94 ENST00000501169.2
DPH6 antisense RNA 1 (head to head)
chr5_+_150404904 0.93 ENST00000521632.1
glutathione peroxidase 3 (plasma)
chr7_+_151653464 0.93 ENST00000431418.2
ENST00000392800.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr5_+_146614579 0.93 ENST00000541094.1
ENST00000398521.3
serine/threonine kinase 32A
chr9_+_71357171 0.93 ENST00000440050.1
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr14_+_60386853 0.91 ENST00000570145.1
leucine rich repeat containing 9
chr8_+_95565947 0.91 ENST00000523011.1
RP11-267M23.4
chr7_+_147830776 0.91 ENST00000538075.1
contactin associated protein-like 2
chr6_+_72922590 0.91 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr9_+_27109440 0.90 ENST00000519080.1
TEK tyrosine kinase, endothelial
chr2_+_108863651 0.90 ENST00000329106.2
ENST00000376700.1
sulfotransferase family, cytosolic, 1C, member 3
chr8_+_39442097 0.90 ENST00000265707.5
ENST00000379866.1
ENST00000520772.1
ENST00000541111.1
ADAM metallopeptidase domain 18
chr6_-_135271219 0.90 ENST00000367847.2
ENST00000367845.2
aldehyde dehydrogenase 8 family, member A1
chr18_+_10526008 0.90 ENST00000542979.1
ENST00000322897.6
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr14_+_32798462 0.89 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr15_-_99791413 0.89 ENST00000394129.2
ENST00000558663.1
ENST00000394135.3
ENST00000561365.1
ENST00000560279.1
tetratricopeptide repeat domain 23
chr14_-_105420241 0.89 ENST00000557457.1
AHNAK nucleoprotein 2
chr5_-_74162605 0.88 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr6_+_151561085 0.88 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr2_+_149974684 0.88 ENST00000450639.1
LY6/PLAUR domain containing 6B
chr3_-_151034734 0.88 ENST00000260843.4
G protein-coupled receptor 87
chr21_+_44073860 0.87 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
phosphodiesterase 9A
chr8_+_67405755 0.87 ENST00000521495.1
chromosome 8 open reading frame 46
chr9_-_104198042 0.86 ENST00000374855.4
aldolase B, fructose-bisphosphate
chr7_+_54398390 0.86 ENST00000458615.1
ENST00000426205.1
RP11-436F9.1
chr1_+_160097462 0.86 ENST00000447527.1
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr5_+_140557371 0.86 ENST00000239444.2
protocadherin beta 8
chr4_+_139230865 0.85 ENST00000502757.1
ENST00000507145.1
ENST00000515282.1
ENST00000510736.1
long intergenic non-protein coding RNA 499
chr18_+_5748793 0.85 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr21_-_34185944 0.85 ENST00000479548.1
chromosome 21 open reading frame 62
chr7_-_107968921 0.85 ENST00000442580.1
neuronal cell adhesion molecule
chr10_+_18689637 0.84 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_123010 0.84 ENST00000382398.3
defensin, beta 126
chr10_+_18240753 0.84 ENST00000377369.2
solute carrier family 39 (zinc transporter), member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.6 1.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.6 1.8 GO:0007412 axon target recognition(GO:0007412)
0.6 1.7 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.6 2.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.5 1.5 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.5 2.4 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 1.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 1.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.4 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.4 1.1 GO:0050894 determination of affect(GO:0050894)
0.4 1.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.4 2.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 1.3 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 7.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 0.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 1.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.3 0.9 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.3 2.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.9 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 3.7 GO:0035766 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.3 1.6 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.5 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.9 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 0.7 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.2 1.9 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 4.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 3.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.8 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.2 2.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 2.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.3 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.2 1.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.6 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.2 0.8 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 1.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 2.4 GO:0006857 oligopeptide transport(GO:0006857)
0.2 0.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.6 GO:0034059 response to anoxia(GO:0034059)
0.2 0.8 GO:0098942 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.2 2.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.9 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.7 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963)
0.2 0.7 GO:0033504 floor plate development(GO:0033504)
0.2 0.5 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 1.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.7 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 1.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.2 3.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 1.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.5 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.2 0.6 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.2 0.9 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.4 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 1.9 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.2 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.1 1.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 2.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.6 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 1.1 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 2.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.6 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.4 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.6 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.6 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.1 2.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.7 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.4 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 3.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.8 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.9 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 2.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.7 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 1.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 2.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 1.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.3 GO:2001303 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 3.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.6 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.2 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 1.2 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 1.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.3 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 2.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 0.3 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) axon midline choice point recognition(GO:0016199) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.0 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.9 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 4.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.4 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.7 GO:0048863 stem cell differentiation(GO:0048863)
0.0 7.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0060459 left lung development(GO:0060459) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 1.1 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.5 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.3 GO:0061141 lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 7.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.5 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.1 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.0 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0009308 amine metabolic process(GO:0009308)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0043473 pigmentation(GO:0043473)
0.0 2.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 1.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0052041 suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.4 GO:0006605 protein targeting(GO:0006605)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 1.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0050808 synapse organization(GO:0050808)
0.0 0.1 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 3.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.8 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 4.2 GO:0007411 axon guidance(GO:0007411)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.4 GO:0014002 astrocyte development(GO:0014002)
0.0 0.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 0.6 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 0.8 GO:0043159 acrosomal matrix(GO:0043159)
0.3 2.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 2.2 GO:0044305 calyx of Held(GO:0044305)
0.2 1.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 2.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 4.7 GO:0043194 axon initial segment(GO:0043194)
0.2 1.7 GO:0070852 cell body fiber(GO:0070852)
0.1 1.2 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 2.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.0 GO:0033010 paranodal junction(GO:0033010)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 3.7 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 0.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 2.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 3.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 3.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.0 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 7.8 GO:0043204 perikaryon(GO:0043204)
0.0 5.5 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 9.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 9.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 4.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 11.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 4.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 1.9 GO:0002113 interleukin-33 binding(GO:0002113)
0.6 1.7 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.5 2.5 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.5 1.5 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.4 1.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 3.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.4 1.5 GO:0005042 netrin receptor activity(GO:0005042)
0.4 3.1 GO:0004064 arylesterase activity(GO:0004064)
0.4 1.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.4 3.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.4 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.3 1.9 GO:0015265 urea channel activity(GO:0015265)
0.3 1.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 3.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 1.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.9 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 0.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.6 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.2 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 6.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 2.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 4.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.6 GO:0004040 amidase activity(GO:0004040)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 3.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 0.5 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2 1.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 7.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.7 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 3.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.3 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.7 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.8 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.7 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.1 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 1.6 GO:0019864 IgG binding(GO:0019864)
0.1 4.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 3.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 1.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 2.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.4 GO:0043295 glutathione binding(GO:0043295)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 4.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 3.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0019841 retinol binding(GO:0019841)
0.0 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 2.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.6 GO:0005549 odorant binding(GO:0005549)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0099589 serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 6.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.2 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0070990 snRNP binding(GO:0070990)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 4.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 13.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.4 PID AURORA B PATHWAY Aurora B signaling
0.0 2.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 3.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 5.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 2.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 4.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 5.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 2.5 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis