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Illumina Body Map 2: averaged replicates

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Results for HNF4A

Z-value: 4.86

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Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
ENSG00000101076.12 HNF4A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg19_v2_chr20_+_42984330_429844450.832.9e-09Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_96698406 28.68 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr17_+_4675175 24.03 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr10_+_96522361 23.86 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr10_-_96829246 23.72 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr10_-_129691195 23.41 ENST00000368671.3
CLRN3
clarin 3
chr5_-_35048047 21.66 ENST00000231420.6
AGXT2
alanine--glyoxylate aminotransferase 2
chr6_+_30130969 21.22 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr3_-_42917363 20.50 ENST00000437102.1
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr20_+_56136136 20.39 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr11_-_116694009 20.31 ENST00000357780.3
APOA4
apolipoprotein A-IV
chr9_+_139839711 19.68 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr17_+_41052808 18.58 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr3_-_120400960 18.25 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr19_+_45449266 18.11 ENST00000592257.1
APOC2
apolipoprotein C-II
chr9_+_139839686 17.98 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr20_-_7921090 17.73 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr6_+_131148538 17.70 ENST00000541421.2
SMLR1
small leucine-rich protein 1
chr19_+_45449228 17.59 ENST00000252490.4
APOC2
apolipoprotein C-II
chr10_+_96443378 17.55 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr6_+_43265992 17.39 ENST00000449231.1
ENST00000372589.3
ENST00000372585.5
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr19_+_45449301 17.24 ENST00000591597.1
APOC2
apolipoprotein C-II
chr1_-_161193349 16.74 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2
apolipoprotein A-II
chr12_+_56075330 16.60 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr1_+_145727681 16.29 ENST00000417171.1
ENST00000451928.2
PDZK1
PDZ domain containing 1
chr17_+_27369918 16.00 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr1_-_155270770 15.91 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr10_+_96443204 15.27 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr1_-_177939041 15.02 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_+_31949801 14.95 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr6_+_31982539 14.59 ENST00000435363.2
ENST00000425700.2
C4B
complement component 4B (Chido blood group)
chr17_-_36105009 14.49 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr1_-_155271213 14.10 ENST00000342741.4
PKLR
pyruvate kinase, liver and RBC
chr3_-_194072019 13.70 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr1_+_196857144 13.58 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr6_+_31950150 13.29 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr3_+_46538981 13.15 ENST00000296142.3
RTP3
receptor (chemosensory) transporter protein 3
chr2_-_21266935 13.02 ENST00000233242.1
APOB
apolipoprotein B
chrX_+_38211777 12.82 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr17_-_7082668 12.05 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr19_-_39303576 11.99 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr12_-_21757774 11.95 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr17_-_7082861 11.67 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr20_-_7238861 11.41 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr1_-_177939348 11.31 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_-_86099898 11.04 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr7_+_45927956 10.98 ENST00000275525.3
ENST00000457280.1
IGFBP1
insulin-like growth factor binding protein 1
chr16_-_16317321 10.93 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr1_-_161207875 10.60 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr19_+_41594377 10.45 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr22_-_42526802 10.31 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
chr19_+_45116921 10.23 ENST00000402988.1
IGSF23
immunoglobulin superfamily, member 23
chr12_+_121416489 10.18 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr12_+_109273806 10.09 ENST00000228476.3
ENST00000547768.1
DAO
D-amino-acid oxidase
chr6_+_43266063 9.95 ENST00000372574.3
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr7_+_45928079 9.83 ENST00000468955.1
IGFBP1
insulin-like growth factor binding protein 1
chr11_-_62997124 9.79 ENST00000306494.6
SLC22A25
solute carrier family 22, member 25
chr19_-_36304201 9.79 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr16_+_8768422 9.71 ENST00000268251.8
ENST00000564714.1
ABAT
4-aminobutyrate aminotransferase
chr17_+_1646130 9.55 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr9_-_136605042 9.47 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH
sarcosine dehydrogenase
chr2_+_44502630 9.34 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr19_+_7660716 9.33 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr11_+_27076764 8.74 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_6508100 8.56 ENST00000461727.1
ESPN
espin
chr5_+_176811431 8.48 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr7_-_15601595 8.47 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr5_-_42812143 8.40 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr1_-_197036364 8.28 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr1_-_60392452 8.21 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr1_-_161208013 8.20 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr5_-_42811986 8.19 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr17_+_77704681 8.10 ENST00000328313.5
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr3_-_53878644 8.08 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr16_+_29690358 7.99 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr2_-_21266816 7.93 ENST00000399256.4
APOB
apolipoprotein B
chr13_+_113777105 7.79 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
F10
coagulation factor X
chr1_-_161207953 7.67 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr3_-_187009798 7.50 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr3_+_46919235 7.47 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr2_-_28113217 7.46 ENST00000444339.2
RBKS
ribokinase
chr6_+_30131318 7.36 ENST00000376688.1
TRIM15
tripartite motif containing 15
chr11_+_63137251 7.24 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr3_-_187009646 6.50 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr17_+_4692230 6.38 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr2_-_31637560 6.28 ENST00000379416.3
XDH
xanthine dehydrogenase
chr1_-_15911510 6.20 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chrX_+_66764375 6.08 ENST00000374690.3
AR
androgen receptor
chr17_-_44896047 5.83 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr1_+_199996733 5.76 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr4_-_88244049 5.74 ENST00000328546.4
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr12_+_121416340 5.72 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr1_-_161207986 5.68 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr2_+_44502597 5.63 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr14_+_38677123 5.57 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr1_+_199996702 5.37 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_-_43019698 5.33 ENST00000431905.1
ENST00000294973.6
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr4_-_88244010 5.30 ENST00000302219.6
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr16_-_87970122 5.29 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr22_+_25003626 5.27 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr3_-_124653579 5.18 ENST00000478191.1
ENST00000311075.3
MUC13
mucin 13, cell surface associated
chr6_+_43028182 5.15 ENST00000394058.1
KLC4
kinesin light chain 4
chr1_+_94883991 5.11 ENST00000370214.4
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr11_+_74870818 4.97 ENST00000525845.1
ENST00000534186.1
ENST00000428359.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr1_+_78511586 4.77 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_+_94883931 4.67 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr17_+_27071002 4.52 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr14_-_23446021 4.47 ENST00000553592.1
AJUBA
ajuba LIM protein
chr12_+_121416437 4.28 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr22_+_25003606 4.17 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr10_+_102106829 4.05 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr16_-_57514277 4.01 ENST00000562008.1
ENST00000567214.1
DOK4
docking protein 4
chr6_+_32146131 3.91 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr1_-_24126892 3.86 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr22_+_25003568 3.73 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr11_-_8816375 3.61 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr4_-_10023095 3.51 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr19_+_10197463 3.50 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr1_+_94884023 3.46 ENST00000315713.5
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr1_-_43751276 3.43 ENST00000423420.1
C1orf210
chromosome 1 open reading frame 210
chr1_+_241695424 3.37 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr13_+_76334567 3.30 ENST00000321797.8
LMO7
LIM domain 7
chr3_-_187009468 3.25 ENST00000425937.1
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr1_+_100435315 3.24 ENST00000370155.3
ENST00000465289.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr8_-_128231299 3.14 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chrX_+_118108571 3.11 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr5_+_133842243 3.09 ENST00000515627.2
AC005355.2
AC005355.2
chr17_-_47786375 3.05 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr6_+_43739697 3.00 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr13_+_76334795 2.91 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr19_+_35630022 2.89 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr7_-_47621229 2.80 ENST00000434451.1
TNS3
tensin 3
chr7_+_192969 2.76 ENST00000313766.5
FAM20C
family with sequence similarity 20, member C
chr14_-_51561784 2.75 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr14_+_39735411 2.45 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chrX_+_118108601 2.45 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr17_-_2614927 2.42 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr11_-_118550346 2.37 ENST00000530256.1
TREH
trehalase (brush-border membrane glycoprotein)
chr1_+_241695670 2.34 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_121163602 2.29 ENST00000411593.2
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr12_-_51422017 2.25 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr9_+_27109133 2.24 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr12_+_121163538 2.22 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr16_+_21244986 2.20 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr14_-_23446003 2.16 ENST00000553911.1
AJUBA
ajuba LIM protein
chr19_+_10196981 2.15 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr1_-_43751230 2.07 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr12_-_7125770 2.07 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr5_+_72469014 2.03 ENST00000296776.5
TMEM174
transmembrane protein 174
chr19_-_10687983 1.98 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr13_+_50656307 1.97 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr13_-_28896641 1.92 ENST00000543394.1
FLT1
fms-related tyrosine kinase 1
chr7_+_33765593 1.91 ENST00000311067.3
RP11-89N17.1
HCG1643653; Uncharacterized protein
chr17_+_4853442 1.90 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr2_+_219135115 1.89 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr13_+_76334498 1.83 ENST00000534657.1
LMO7
LIM domain 7
chr20_+_36661910 1.82 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr9_-_27005686 1.82 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr12_+_56114189 1.79 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr15_-_63448973 1.78 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr9_-_71155783 1.76 ENST00000377311.3
TMEM252
transmembrane protein 252
chr12_+_56114151 1.75 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr4_+_159593271 1.69 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr17_-_17494972 1.67 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT
phosphatidylethanolamine N-methyltransferase
chr3_+_124303539 1.59 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr6_+_30881982 1.59 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr14_-_39572279 1.58 ENST00000536508.1
SEC23A
Sec23 homolog A (S. cerevisiae)
chr7_+_100547156 1.54 ENST00000379458.4
MUC3A
Protein LOC100131514
chr2_+_173724771 1.52 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_79717163 1.48 ENST00000520269.1
IL7
interleukin 7
chr19_+_35629702 1.48 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr17_-_2615031 1.45 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr15_-_41120896 1.41 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr12_+_53497263 1.34 ENST00000551896.1
ENST00000301466.3
SOAT2
sterol O-acyltransferase 2
chr6_+_80341000 1.25 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr16_+_81272287 1.25 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr9_-_116065551 1.22 ENST00000297894.5
RNF183
ring finger protein 183
chr5_+_34757309 1.16 ENST00000397449.1
RAI14
retinoic acid induced 14
chr11_+_119056178 1.15 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr6_+_30882108 1.13 ENST00000541562.1
ENST00000421263.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr19_-_15235906 1.03 ENST00000600984.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr19_-_49339080 1.03 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr18_-_61034743 1.02 ENST00000406396.3
KDSR
3-ketodihydrosphingosine reductase
chr19_+_4639514 1.01 ENST00000327473.4
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_+_113217345 0.98 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr18_-_54318353 0.93 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr1_+_113217043 0.92 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_180601139 0.90 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr2_-_27603582 0.88 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr2_-_62733476 0.88 ENST00000335390.5
TMEM17
transmembrane protein 17
chr11_-_32456891 0.82 ENST00000452863.3
WT1
Wilms tumor 1
chr8_+_96037205 0.80 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_+_113217073 0.79 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_100435535 0.79 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr11_-_63536113 0.78 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr10_+_99349450 0.75 ENST00000370640.3
C10orf62
chromosome 10 open reading frame 62
chr1_+_113217309 0.74 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_+_101142722 0.74 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7
ankyrin repeat and SOCS box containing 7
chr2_+_120303717 0.73 ENST00000594371.1
PCDP1
Primary ciliary dyskinesia protein 1
chr15_-_100273544 0.73 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr11_-_65381643 0.72 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 52.9 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
9.5 28.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
9.0 62.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
8.7 34.7 GO:0035565 regulation of pronephros size(GO:0035565)
7.2 21.7 GO:0009436 glyoxylate catabolic process(GO:0009436)
5.6 16.7 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
5.2 41.3 GO:0034371 chylomicron remodeling(GO:0034371)
5.1 20.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
5.0 10.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
4.7 23.7 GO:0002933 lipid hydroxylation(GO:0002933)
4.3 12.8 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
3.8 30.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
3.7 11.2 GO:0097187 dentinogenesis(GO:0097187)
3.3 13.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
3.2 9.5 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
2.4 42.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.3 51.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
2.3 16.0 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
2.2 17.7 GO:0009441 glycolate metabolic process(GO:0009441)
2.2 2.2 GO:1904106 protein localization to microvillus(GO:1904106)
2.1 19.0 GO:0046874 quinolinate metabolic process(GO:0046874)
2.0 6.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
2.0 18.2 GO:0006572 tyrosine catabolic process(GO:0006572)
2.0 8.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.9 5.8 GO:0060061 Spemann organizer formation(GO:0060061)
1.9 9.7 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
1.9 15.0 GO:0015811 L-cystine transport(GO:0015811)
1.7 37.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.6 6.3 GO:0046110 xanthine metabolic process(GO:0046110)
1.5 18.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.5 7.5 GO:0019303 D-ribose catabolic process(GO:0019303)
1.4 9.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.4 9.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.3 4.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.3 26.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.2 13.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
1.1 5.6 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.1 17.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.1 17.0 GO:0015747 urate transport(GO:0015747)
1.0 3.0 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
1.0 7.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.9 9.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.9 8.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.9 6.2 GO:0008295 spermidine biosynthetic process(GO:0008295) primary amino compound biosynthetic process(GO:1901162)
0.8 8.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.8 32.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.8 4.0 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.8 3.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.7 2.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.7 8.7 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.6 1.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.6 8.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 8.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.6 19.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 4.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5 6.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 2.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 16.3 GO:0015879 carnitine transport(GO:0015879)
0.4 2.2 GO:0015692 lead ion transport(GO:0015692)
0.3 11.0 GO:0034389 lipid particle organization(GO:0034389)
0.3 3.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 13.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 1.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 2.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 7.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3 15.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.3 3.5 GO:0046415 urate metabolic process(GO:0046415)
0.2 23.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 32.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.2 3.9 GO:0019388 galactose catabolic process(GO:0019388)
0.2 27.3 GO:0030449 regulation of complement activation(GO:0030449)
0.2 0.8 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.2 5.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 3.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 1.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.8 GO:0048286 lung alveolus development(GO:0048286)
0.1 11.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.6 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 2.4 GO:0005984 disaccharide metabolic process(GO:0005984) oligosaccharide catabolic process(GO:0009313)
0.1 0.5 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 5.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.9 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.9 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 1.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.3 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 4.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 3.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.0 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 5.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.9 GO:0006735 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.5 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0060395 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) SMAD protein signal transduction(GO:0060395)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 9.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 11.0 GO:0042493 response to drug(GO:0042493)
0.0 1.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 73.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
3.8 37.7 GO:0005579 membrane attack complex(GO:0005579)
1.9 9.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.9 37.0 GO:0042627 chylomicron(GO:0042627)
0.7 55.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 9.6 GO:0005577 fibrinogen complex(GO:0005577)
0.5 8.6 GO:0032426 stereocilium tip(GO:0032426)
0.5 16.3 GO:0031528 microvillus membrane(GO:0031528)
0.4 5.8 GO:1990909 Wnt signalosome(GO:1990909)
0.4 2.2 GO:0070826 paraferritin complex(GO:0070826)
0.4 9.3 GO:0005915 zonula adherens(GO:0005915)
0.3 7.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 21.5 GO:0031526 brush border membrane(GO:0031526)
0.2 6.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 56.5 GO:0072562 blood microparticle(GO:0072562)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 1.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 4.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 227.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 11.0 GO:0005811 lipid particle(GO:0005811)
0.1 8.8 GO:0005902 microvillus(GO:0005902)
0.1 11.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 26.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 46.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.6 GO:0005871 kinesin complex(GO:0005871)
0.0 9.4 GO:0009986 cell surface(GO:0009986)
0.0 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 8.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 17.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 9.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 3.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.5 GO:0055037 recycling endosome(GO:0055037)
0.0 5.3 GO:0043296 apical junction complex(GO:0043296)
0.0 9.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.8 GO:0030425 dendrite(GO:0030425)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 74.5 GO:0070062 extracellular exosome(GO:0070062)
0.0 8.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 26.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 52.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
7.6 52.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
6.8 20.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
6.4 38.2 GO:0004882 androgen receptor activity(GO:0004882)
5.9 17.7 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
5.0 30.0 GO:0004743 pyruvate kinase activity(GO:0004743)
4.6 18.6 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
4.6 37.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
3.6 75.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
3.5 20.9 GO:0035473 lipase binding(GO:0035473)
3.2 9.5 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
3.1 21.7 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
2.8 28.2 GO:0001849 complement component C1q binding(GO:0001849)
2.7 16.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.6 23.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
2.4 9.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.2 8.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
2.0 16.3 GO:0005124 scavenger receptor binding(GO:0005124)
1.9 9.7 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.9 13.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.9 13.2 GO:0031849 olfactory receptor binding(GO:0031849)
1.9 15.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
1.7 52.2 GO:0001848 complement binding(GO:0001848)
1.7 12.0 GO:0016936 galactoside binding(GO:0016936)
1.6 8.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.5 7.5 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
1.5 20.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.3 30.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.2 20.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.1 5.6 GO:0004994 somatostatin receptor activity(GO:0004994)
1.0 3.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.9 11.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.9 32.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.8 4.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.8 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 13.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 8.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.7 6.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.6 1.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.6 8.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.6 23.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.6 12.8 GO:0042301 phosphate ion binding(GO:0042301)
0.6 8.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 10.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.6 1.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.6 1.7 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.5 3.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 15.8 GO:0071949 FAD binding(GO:0071949)
0.5 2.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 4.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.4 1.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.4 2.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 6.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 2.2 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 5.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 12.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 4.5 GO:0031996 thioesterase binding(GO:0031996)
0.3 6.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 4.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 3.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 7.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 9.3 GO:0030507 spectrin binding(GO:0030507)
0.1 14.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 1.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 3.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 22.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 5.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 8.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 13.6 GO:0005319 lipid transporter activity(GO:0005319)
0.1 1.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 9.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 4.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 12.7 GO:0008168 methyltransferase activity(GO:0008168)
0.0 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 13.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 6.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 7.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 11.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 124.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.6 59.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 4.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 32.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 5.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 53.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 15.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 129.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.0 90.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.7 45.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.4 20.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2 21.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.2 50.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.2 37.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.1 20.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.1 22.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.1 27.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.8 16.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 20.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 6.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 11.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.5 13.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 10.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 5.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 34.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 18.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 13.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 9.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 6.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 4.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 4.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 15.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 59.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 5.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 8.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 8.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 5.1 REACTOME KINESINS Genes involved in Kinesins
0.1 13.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 8.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 13.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 8.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 4.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.9 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 3.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation